International evidence-based guidelines on point of care ultrasound (POCUS) for critically ill neonates and children issued by the POCUS working group of the European society of paediatric and neonatal intensive care (ESPNIC)
Open accessAbstract
BACKGROUND: Point-of-care ultrasound (POCUS) is nowadays an essential tool in critical care. Its role seems more important in neonates and children where other monitoring techniques may be unavailable. POCUS Working Group of the European Society of Paediatric and Neonatal Intensive Care (ESPNIC) aimed to provide evidence-based clinical guidelines for the use of POCUS in critically ill neonates and children. METHODS: Creation of an international Euro-American panel of paediatric and neonatal intensivists expert in POCUS and systematic review of relevant literature. A literature search was performed, and the level of evidence was assessed according to a GRADE method. Recommendations were developed through discussions managed following a Quaker-based consensus technique and evaluating appropriateness using a modified blind RAND/UCLA voting method. AGREE statement was followed to prepare this document. RESULTS: Panellists agreed on 39 out of 41 recommendations for the use of cardiac, lung, vascular, cerebral and abdominal POCUS in critically ill neonates and children. Recommendations were mostly (28 out of 39) based on moderate quality of evidence (B and C). CONCLUSIONS: Evidence-based guidelines for the use of POCUS in critically ill neonates and children are now available. They will be useful to optimise the use of POCUS, training programs and further research, which are urgently needed given the weak quality of evidence available.
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Echocardiography can easily and rapidly quantify ventricular function and size to guide circulation management.
“Echocardiography can easily and rapidly quantify ventricular function and size to guide circulation management (2)”
From Innovative wearable technology for continuous echocardiographic monitoring: first-in-neonate case report (2025) · cites this paper as [2]
The Results section says cardiac POCUS can assess ventricular function semi-quantitatively in critically ill neonates and children and describes measures of ventricular dimensions. It does not establish that function and size can be easily and rapidly quantified; it specifies that detailed functional assessment requires advanced echocardiography training. Its discussion of filling and fluid responsiveness supports a role in circulation assessment, but is narrower than the claim. (LLM, conf=0.86)
Experimental — accuracy not yet measuredEchocardiography is widely used in the cardiac evaluation of critically ill neonates.
“which is widely used in the cardiac evaluation of critically ill neonates”
From Innovative wearable technology for continuous echocardiographic monitoring: first-in-neonate case report (2025) · cites this paper as [2]
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Transplacental transmission of SARS-CoV-2 infection
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Ultrasound Guided Catheter Tip Location in Neonates: A Prospective Cohort Study
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Life-threatening PPHN refractory to nitric oxide: proposal for a rational therapeutic algorithm
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Lung Ultrasound in Neonatal Respiratory Distress Syndrome: A Narrative Review of the Last 10 Years
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Characteristics of scores used for quantitative lung ultrasound in neonates: a systematic review
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Multisystem inflammatory syndrome in neonates (MIS-N): a systematic review
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How to recognize a trustworthy clinical practice guideline
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Point-of-Care Ultrasound for the Diagnosis of Frequent Cardiovascular Diseases: A Review
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- Authors
- Singh, Y., Tissot, C., Fraga, M. V., Yousef, N., Cortes, R. G., Lopez, J., Sanchez-de-Toledo, J., Brierley, J., Colunga, J. M., Raffaj, D., Da Cruz, E., Durand, P., Kenderessy, P., Lang, H.-J., Nishisaki, A., Kneyber, M. C., Tissieres, P., Conlon, T. W., & De Luca, D.
- Affiliations
- University of Cambridge (GB)
- Assistance Publique – Hôpitaux de Paris (FR)
- Great Ormond Street Hospital (GB)
- Instituto de Salud Carlos III (ES)
- Nottingham University Hospitals NHS Trust (GB)
- Médecins Sans Frontières (CH)
- Children's Hospital of Philadelphia (US)
- University Medical Center Groningen (NL)
- Corresponding author
- Singh, Yogen
- ORCID
- Venue
- Critical Care
- Published
- 2020-02-24
- Volume
- 24
- Issue
- 1
- Pages
- 65-65
- ISSN
- 1364-8535 (ISSN-L)
- PMC
- PMC7041196
- OpenAlex
- W3007973847
- Cited by
- 659
- References
- 176
- Citations by year
- 2026: 105 · 2025: 107 · 2024: 80 · 2023: 115 · 2022: 124 · 2021: 81 · 2020: 43 · 2019: 1 · 2015: 1
- FWCI
- 57.62
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Critical Care (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (publishedVersion, cc-by)
- Apollo (University of Cambridge) (submittedVersion, cc-by)
- HAL (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion, cc-by)
- Apollo (cc-by)
- Topics
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Ultrasound in Clinical Applications
- Health Sciences › Medicine › Epidemiology › Sepsis Diagnosis and Treatment
- Health Sciences › Medicine › Surgery › Hemodynamic Monitoring and Therapy
- Keywords
- point-of-care ultrasound, critically ill neonates, critically ill children, echocardiography, lung ultrasound, vascular ultrasound, cerebral ultrasound, abdominal ultrasound, pediatric intensive care, neonatal intensive care, ultrasound training
- MeSH terms
- Systematic Reviews as Topic, Critical Care, Humans, Infant, Newborn, Intensive Care Units, Neonatal, Ultrasonography, Intensive Care, Neonatal, Critical Illness, Point-of-Care Systems
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