DNA methylation changes of whole blood cells in response to active smoking exposure in adults: a systematic review of DNA methylation studies

Aspirin plus Clopidogrel as Secondary Prevention after Stroke or Transient Ischemic Attack: A Systematic Review and Meta-Analysis

Zhang, Q., Wang, C., Zheng, M., Li, Y., Li, J., Zhang, L., Shang, X., & Yan, C. (2014) · Cerebrovascular Diseases · doi:10.1159/000369778 · Cited by 11,609

Projections of Global Mortality and Burden of Disease from 2002 to 2030

Mathers, C. D., & Loncar, D. (2006) · PLoS Medicine · doi:10.1371/journal.pmed.0030442 · Cited by 11,386

DNA methylation arrays as surrogate measures of cell mixture distribution

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Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

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Evaluation of the endorsement of the preferred reporting items for systematic reviews and meta-analysis (PRISMA) statement on the quality of published systematic review and meta-analyses

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Tobacco smoking leads to extensive genome-wide changes in DNA methylation

Zeilinger, S., Kühnel, B., Klopp, N., Baurecht, H., Kleinschmidt, A., Gieger, C., Weidinger, S., Lattka, E., Adamski, J., Peters, A., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0063812 · Cited by 824

Tobacco-smoking-related differential DNA methylation: 27K discovery and replication

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Epigenome-wide association study in the European Prospective Investigation into Cancer and Nutrition (EPIC-Turin) identifies novel genetic loci associated with smoking

Shenker, N. S., Polidoro, S., van Veldhoven, K., Sacerdote, C., Ricceri, F., Birrell, M. A., Belvisi, M. G., Brown, R., Vineis, P., & Flanagan, J. M. (2013) · Human Molecular Genetics · doi:10.1093/hmg/dds488 · Cited by 396

Cigarette smoking and DNA methylation

Lee, K. W. K., & Pausová, Z. (2013) · Frontiers in Genetics · doi:10.3389/fgene.2013.00132 · Cited by 384

Dynamics of smoking-induced genome-wide methylation changes with time since smoking cessation

Guida, F., Sandanger, T. M., Castagné, R., Campanella, G., Polidoro, S., Palli, D., Krogh, V., Tumino, R., Sacerdote, C., Panico, S., et al. (2015) · Human Molecular Genetics · doi:10.1093/hmg/ddu751 · Cited by 331

High-dimensional mediation analysis for continuous outcome with confounders using overlap weighting method in observational epigenetic study

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Normal bronchial field basal cells show persistent methylome-wide impact of tobacco smoking, including in known cancer genes

Khulan, B., Ye, K. Q., Shi, M. K., Waldman, S., Marsh, A., Siddiqui, T., Okorozo, A., Desai, A., Patel, D. M., Dobkin, J. B., et al. (2025) · Epigenetics · doi:10.1080/15592294.2025.2466382 · Cited by 3

Smoking May Affect Pulmonary Function through DNA Methylation: an Epigenome-Wide Association Study in Korean Men

Kwak, S., Park, C. Y., & Shin, M. (2020) · Clinical Nutrition Research · doi:10.7762/cnr.2020.9.2.134 · Cited by 3

Cell-Type Heterogeneity in DNA Methylation Studies: Statistical Methods and Guidelines

Teschendorff, A. E. (2022) · Springer eBooks · doi:10.1007/978-3-030-94475-9_4 · Cited by 2

The association between DNA methylation of 6p21.33 and AHRR in blood and coronary heart disease in Chinese population

Zhu, L., Zhu, C., Wang, J., Yang, R., & Zhao, X. (2022) · BMC Cardiovascular Disorders · doi:10.1186/s12872-022-02766-8 · Cited by 3

Cigarette smoke exposure accelerates AML progression in FLT3-ITD models

Figueroa, M., Ma, H., Alfayez, M., Morales-Mantilla, D. E., Wang, F., Lu, Y., Estecio, M. R., King, K. Y., Kleinerman, E. S., Moghaddam, S. J., et al. (2023) · Blood Advances · doi:10.1182/bloodadvances.2023010111 · Cited by 3

Impact of smoking hookah and bidi on global DNA methylation: a community-based study from Haryana, North India

Tyagi, S., Kaushik, A., Jain, S. G., Chaudhary, V., & Saraswathy, K. N. (2024) · Discover Medicine · doi:10.1007/s44337-024-00064-0 · Cited by 3

DNA Methylation and Smoking: Implications for Understanding Effects of Electronic Cigarettes

Freudenheim, J. L., Shields, P. G., Song, M., & Smiraglia, D. J. (2019) · Current Epidemiology Reports · doi:10.1007/s40471-019-00191-8 · Cited by 4

Comprehensive analysis reveals common DNA methylation patterns of tobacco-associated cancers: A pan-cancer analysis

Liu, X., Chen, J., Li, J., Zeng, Z., Jiang, X., Gao, Y., Huang, Z., Wu, Q., Gong, Y. Q., & Xie, C. (2021) · Gene · doi:10.1016/j.gene.2021.145900 · Cited by 3

A DNA Methylation Marker, cg05575921 ( AHRR ), Outperforms Self-Reported Smoking Exposure for Its Association With Cardiovascular Disease Prevalence

Jones, G. T., Williams, M. J. A., Khashram, M., Fitzgerald, S. J., Lyons, O., Griffin, C. L., Lesche, S., Krysa, J., & Coffey, S. (2025) · Nicotine & Tobacco Research · doi:10.1093/ntr/ntaf165 · Cited by 2

Epigenetics and multiple sclerosis

Kular, L., Castelo‐Branco, G., & Jagodic, M. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800226-1.00010-1 · Cited by 2

Cognition, Aryl Hydrocarbon Receptor Repressor Methylation, and Abstinence Duration-Associated Multimodal Brain Networks in Smoking and Long-Term Smoking Cessation

Qi, S., Fu, Z., Wu, L., Calhoun, V. D., Zhang, D., Daughters, S. B., Hsu, P.-C., Jiang, R., Vergara, V. M., Jing Sui （Beijing Normal University）， my correct affiliation is beijing normal university, N. Q. U. O. S. A. T., et al. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.923065 · Cited by 2

DNA Methylation in Multiple Sclerosis

Kular, L., & Jagodic, M. (2019) · RNA technologies · doi:10.1007/978-3-030-14792-1_8 · Cited by 2

Effect of hubble-bubble smoking on global DNA methylation and transcription levels of protamine and histone genes in human spermatozoa

Laqqan, M. M., & Yassin, M. M. (2023) · Journal of Environmental Science and Health Part A · doi:10.1080/10934529.2023.2174326 · Cited by 2

Impact of waterpipe and tobacco cigarette smoking on global DNA methylation and nuclear proteins genes transcription in spermatozoa: a comparative investigation

Laqqan, M. M., Alghora, S. S., & Yassin, M. M. (2023) · Inhalation Toxicology · doi:10.1080/08958378.2023.2208608 · Cited by 2

Testing for the causal mediation effects of multiple mediators using the kernel machine difference method in genome-wide epigenetic studies

Shen, J., Schwartz, J. D., Baccarelli, A., & Lin, X. (2024) · The Annals of Applied Statistics · doi:10.1214/23-aoas1814 · Cited by 2

Epigenetics and cerebrovascular diseases

Soriano‐Tárraga, C., Jiménez-Conde, J., & Roquer, J. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800226-1.00014-9 · Cited by 2

Effects of Centrifugation at Different Levels of Freeze-Thawed Blood on DNA Isolation

Arslan, M. (2022) · Yüzüncü Yıl Üniversitesi Fen Bilimleri Enstitüsü Dergisi · doi:10.53433/yyufbed.1130525 · Cited by 1

An Emerging Approach of Age‐Related Hearing Loss Research: Application of Integrated Multi‐Omics Analysis

Liu, Y., Zeng, X., & Zhang, H. (2024) · Advanced Biology · doi:10.1002/adbi.202300613 · Cited by 2

Smoking‐independent DNA methylation markers for lung cancer risk: External validation in a large population‐based cohort study

Zhao, Z., Bhardwaj, M., Fan, Z., Li, X., Schrotz‐King, P., & Brenner, H. (2024) · Cancer Science · doi:10.1111/cas.16414 · Cited by 2

EWAS in COPD by biomass-burning smoke exposure identifies low levels of endothelin-1 by hypermethylation of EDN1

García-Carmona, S., Falfán‐Valencia, R., Fernández-López, J. C., Ramírez‐Venegas, A., Morales‐González, F., Ramírez-Díaz, M. E., Cruz-Vicente, F., Martínez-Gómez, M. D. L., Hernández-Zenteno, R. D. J., Fricke-Galindo, I., et al. (2025) · Epigenomics · doi:10.1080/17501911.2025.2535966 · Cited by 1

AHRR DNA Methylation Levels in Leukocytes Identify People at Risk for Cancer Mortality Overlooked by Questionnaire-Based Smoking Indices

Tsuboi, Y., Yamada, H., Fujii, R., Yamazaki, M., Munetsuna, E., Ando, Y., Mizuno, G., Hattori, Y., Okumiyama, H., Murakami, K., et al. (2025) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-25-0625 · Cited by 1

Understanding the Roles of Genetic and Environmental Influences on the Neurobiology of Nicotine Use

Prom‐Wormley, E. C., Langi, G. G., Clifford, J. S., & Real, J. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-805373-7.00023-2 · Cited by 1

An Overview of Epigenetic Correlates of Human Chronic Pain Conditions

Ren, K., & Bai, G. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-814070-3.00011-9 · Cited by 1

Correcting for cell-type heterogeneity in epigenome-wide association studies: premature analyses and conclusionsPreprint

Zheng, S., Beck, S., Jaffe, A. E., Koestler, D. C., Hansen, K. D., Houseman, E. A., Irizarry, R. A., Widschwendter, M., & Teschendorff, A. E. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/121533 · Cited by 1

Tensorial blind source separation for improved analysis of multi-omic dataPreprint

Teschendorff, A. E., Han, J. Y., Paul, D. S., Virta, J., & Nordhausen, K. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/300277 · Cited by 1

Inferring metabolite interactomes via molecular structure informed Bayesian graphical model selection with an application to coronary artery diseasePreprint

Trainor, P. J., Mitchell, J. M., Carlisle, S. M., Moseley, H., DeFilippis, A. P., & Rai, S. N. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/386409 · Cited by 1

Calling differential DNA methylation at cell-type resolution: avoiding misconceptions and promoting best practicesPreprint

Han, J., Zheng, S., Breeze, C. E., Beck, S., & Teschendorff, A. E. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.02.28.433245 · Cited by 1

The Association Between DNA Methylation of 6p21.33 and AHRR in Blood and Coronary Heart Disease in Chinese PopulationPreprint

Zhu, L., Zhu, C., Wang, J., Yang, R., & Zhao, X. (2022) · Research Square · doi:10.21203/rs.3.rs-839939/v1 · Cited by 1

A validated restriction enzyme ddPCR cg05575921 (AHRR) assay to accurately assess smoking exposurePreprint

Fitzgerald, S. J., Bhat, B. A., Print, C. G., & Jones, G. T. (2023) · Research Square · doi:10.21203/rs.3.rs-3350202/v1 · Cited by 1

Smoking drives an epigenetic memory of aberrant hematopoiesisPreprint

Breeze, C. E., Goodney, G. A., Wang, H., Hubbard, A. K., Lim, J., Machiela, M. J., Hoang, T. T., Richards-Barber, M., Tran, C., Tolentino, M., et al. (2026) · medRxiv · doi:10.64898/2026.05.14.26353250 · Cited by 1

An epigenome-wide association study of educational attainment ( n = 10,767)Preprint

Linnér, R. K., Marioni, R. E., Rietveld, C. A., Simpkin, A. J., Davies, N. M., Watanabe, K., Armstrong, N. J., Auro, K. M., Baumbach, C., Bonder, M. J., et al. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/114637 · Cited by 1

DNA Methylation Analysis Reveals a Strong Connection Between Tobacco Smoking and Cancer Pathogenesis

Li, M. D. (2018) · Springer eBooks · doi:10.1007/978-981-10-7530-8_17

Association and interplay of genetic and epigenetic variants in smoking behavior

Gupta, R. (2018) · Työväentutkimus Vuosikirja

Bayesian analytical approaches for metabolomics : a novel method for molecular structure-informed metabolite interaction modeling, a novel diagnostic model for differentiating myocardial infarction type, and approaches for compound identification given mass spectrometry data.

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À la recherche du temps perdu: Smoking and Genomic Imprinting.

Eissenberg, J. C. (2017) · Europe PMC (PubMed Central)

Substance Dependence: Overview of the Environmental, Genetic, Epigenetic, and Imaging Studies

Gupta, R., & Sharma, A. (2019) · Springer eBooks · doi:10.1007/978-981-13-7142-4_6

From tobacco smoking to mutational signature: the role of epigenetic changes in human cancersPreprint

Chen, Z., Wen, W., Cai, Q., Long, J., Wang, Y., Lin, W., Shu, X., Zheng, W., & Guo, X. (2020) · doi:10.21203/rs.2.21105/v1

Revealing the biological basis of mental illness: epigenetic research as a new direction in diagnosis and treatment

Егорович, Х. С., Ivanov, M. V., Sogoyan, M. V., Yanushko, M. G., Tumova, M. A., Муслимова, Л. М., Stanovaya, V. V., Khutoryanskaya, Y. V., & Vissarionov, S. V. (2021) · V M BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY · doi:10.31363/2313-7053-2021-56-3-19-31

Epigenetics in COPD: An Epidemiological Point of View

de Vries, M., & Boezen, H. M. (2020) · Elsevier eBooks · doi:10.1016/b978-0-08-102723-3.00042-1

Overexpression of Cancer- and Neurotransmitter-Associated Genes in the Nucleus Accumbens of SmokersPreprint

Stein, R., Mamdani, F., Bunney, B. G., Cartagena, P. M., Vawter, M. P., Schatzberg, A. F., Barchas, J. D., Lee, F. S., Myers, R., Watson, S. J., et al. (2022) · medRxiv · doi:10.1101/2022.09.30.22280587

The Scenario of Recurrence of Cervical Cancer by Epigenetics

Gaikwad, S. (2023) · International Journal for Research in Applied Science and Engineering Technology · doi:10.22214/ijraset.2023.57250

A validated restriction enzyme ddPCR cg05575921 (AHRR) assay to accurately assess smoking exposure.Preprint

Fitzgerald, S. J., Bhat, B. A., Print, C. G., & Jones, G. T. (2024) · Research Square · doi:10.21203/rs.3.rs-3350202/v2

Pathobiology of Non-neovascular Age-Related Macular Degeneration

Handa, J. T. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13820-1.00030-x

Additional file 3 of Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR

Scherer, M., Gasparoni, G., Rahmouni, S., Shashkova, T., Arnoux, M., Louis, E. J., Nostaeva, A. V., Avalos, D., Dermitzakis, E. T., Aulchenko, Y. S., et al. (2021) · Figshare · doi:10.6084/m9.figshare.16632882

Additional file 4 of A variability in response of osteoclasts to zoledronic acid is mediated by smoking-associated modification in the DNA methylome

Tan, Q., Møller, A. M. J., Qiu, C., Madsen, J. S., Shen, H., Bechmann, T., Delaissé, J., Kristensen, B. W., Deng, H., Karasik, D., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22619378

Additional file 5 of A variability in response of osteoclasts to zoledronic acid is mediated by smoking-associated modification in the DNA methylome

Tan, Q., Møller, A. M. J., Qiu, C., Madsen, J. S., Shen, H., Bechmann, T., Delaissé, J., Kristensen, B. W., Deng, H., Karasik, D., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22619381

Additional file 7 of A variability in response of osteoclasts to zoledronic acid is mediated by smoking-associated modification in the DNA methylome

Tan, Q., Møller, A. M. J., Qiu, C., Madsen, J. S., Shen, H., Bechmann, T., Delaissé, J., Kristensen, B. W., Deng, H., Karasik, D., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22619387

Additional file 3 of Leveraging biological and statistical covariates improves the detection power in epigenome-wide association testing

Huang, J., Bai, L., Cui, B., Wu, L. L., Wang, L., An, Z., Ruan, S., Yu, Y., Zhang, X., & Chen, J. (2020) · Figshare · doi:10.6084/m9.figshare.12097344

Additional file 2 of Leveraging biological and statistical covariates improves the detection power in epigenome-wide association testing

Huang, J., Bai, L., Cui, B., Wu, L. L., Wang, L., An, Z., Ruan, S., Yu, Y., Zhang, X., & Chen, J. (2020) · Figshare · doi:10.6084/m9.figshare.12097338

Additional file 8 of Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR

Scherer, M., Gasparoni, G., Rahmouni, S., Shashkova, T., Arnoux, M., Louis, E. J., Nostaeva, A. V., Avalos, D., Dermitzakis, E. T., Aulchenko, Y. S., et al. (2021) · Figshare · doi:10.6084/m9.figshare.16632900

Additional file 5 of Leveraging biological and statistical covariates improves the detection power in epigenome-wide association testing

Huang, J., Bai, L., Cui, B., Wu, L. L., Wang, L., An, Z., Ruan, S., Yu, Y., Zhang, X., & Chen, J. (2020) · Figshare · doi:10.6084/m9.figshare.12097356

Additional file 2 of Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR

Scherer, M., Gasparoni, G., Rahmouni, S., Shashkova, T., Arnoux, M., Louis, E. J., Nostaeva, A. V., Avalos, D., Dermitzakis, E. T., Aulchenko, Y. S., et al. (2021) · Figshare · doi:10.6084/m9.figshare.16632879

Additional file 1 of From tobacco smoking to cancer mutational signature: a mediation analysis strategy to explore the role of epigenetic changes

Chen, Z., Wen, W., Cai, Q., Long, J., Wang, Y., Lin, W., Shu, X., Zheng, W., & Guo, X. (2020) · Figshare · doi:10.6084/m9.figshare.12955300

Additional file 6 of Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR

Scherer, M., Gasparoni, G., Rahmouni, S., Shashkova, T., Arnoux, M., Louis, E. J., Nostaeva, A. V., Avalos, D., Dermitzakis, E. T., Aulchenko, Y. S., et al. (2021) · Figshare · doi:10.6084/m9.figshare.16632891

Additional file 5 of Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR

Scherer, M., Gasparoni, G., Rahmouni, S., Shashkova, T., Arnoux, M., Louis, E. J., Nostaeva, A. V., Avalos, D., Dermitzakis, E. T., Aulchenko, Y. S., et al. (2021) · Figshare · doi:10.6084/m9.figshare.16632888

Additional file 3 of A variability in response of osteoclasts to zoledronic acid is mediated by smoking-associated modification in the DNA methylome

Tan, Q., Møller, A. M. J., Qiu, C., Madsen, J. S., Shen, H., Bechmann, T., Delaissé, J., Kristensen, B. W., Deng, H., Karasik, D., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22619375

Additional file 7 of Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR

Scherer, M., Gasparoni, G., Rahmouni, S., Shashkova, T., Arnoux, M., Louis, E. J., Nostaeva, A. V., Avalos, D., Dermitzakis, E. T., Aulchenko, Y. S., et al. (2021) · Figshare · doi:10.6084/m9.figshare.16632894

Additional file 2 of DNA methylation biomarkers of myocardial infarction and cardiovascular disease

Fernández‐Sanlés, A., Sayols-Baixeras, S., Subirana, I., Sentı́, M., Pérez-Fernández, S., Moura, M. D. C., Esteller, M., Marrugat, J., & Elosúa, R. (2021) · Figshare · doi:10.6084/m9.figshare.14462550

Additional file 4 of Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR

Scherer, M., Gasparoni, G., Rahmouni, S., Shashkova, T., Arnoux, M., Louis, E. J., Nostaeva, A. V., Avalos, D., Dermitzakis, E. T., Aulchenko, Y. S., et al. (2021) · Figshare · doi:10.6084/m9.figshare.16632885

Additional file 1 of Leveraging biological and statistical covariates improves the detection power in epigenome-wide association testing

Huang, J., Bai, L., Cui, B., Wu, L. L., Wang, L., An, Z., Ruan, S., Yu, Y., Zhang, X., & Chen, J. (2020) · Figshare · doi:10.6084/m9.figshare.12097329

Additional file 4 of Leveraging biological and statistical covariates improves the detection power in epigenome-wide association testing

Huang, J., Bai, L., Cui, B., Wu, L. L., Wang, L., An, Z., Ruan, S., Yu, Y., Zhang, X., & Chen, J. (2020) · Figshare · doi:10.6084/m9.figshare.12097353

Additional file 6 of A variability in response of osteoclasts to zoledronic acid is mediated by smoking-associated modification in the DNA methylome

Tan, Q., Møller, A. M. J., Qiu, C., Madsen, J. S., Shen, H., Bechmann, T., Delaissé, J., Kristensen, B. W., Deng, H., Karasik, D., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22619384

Addressing Breast Cancer Disparities in Advancements for Conquering Drug Resistance

Marima, R. M., Fadebi, O. O., Mosoane, B., Basera, A., Gabada, L., Mphahlele, L., Nyalambisa, A., Sambo, E., Dumakude, T. P., Davis, M. B., et al. (2024) · Springer eBooks · doi:10.1007/978-3-031-52860-6_15

Heterogeneity of thymic output in elderly and its association with sex and smokingPreprint

Longhi, M. P., Sandhar, B. S., Vyas, V. S., Harding, D., Ragazzini, R., Bonfanti, P., Marelli‐Berg, F. M., Bell, C. G., & Chain, B. (2024) · Research Square · doi:10.21203/rs.3.rs-3559323/v1

Smoking, Epigenetic DNA Methylation, and Pancreatic Ductal Adenocarcinoma Risk: A Prospective Cohort and Mendelian Randomization StudyPreprint

Zhan, Y., Li, T., Hui, M., Bai, H., Dong, W., Wu, J., Li, X., & Xu, H. (2025) · SSRN Electronic Journal · doi:10.2139/ssrn.5363069

DNA methylation differences stratified by normalized fetal/placental weight ratios suggest neurodevelopmental deficits in neonates with congenital heart disease

Jacobwitz, M., Xie, H. M., Catalano, J. L., Helbig, I., Gaynor, J. W., Burnham, N. B., Linn, R. L., Gebb, J. S., Russell, M. W. W., Hakonarson, H. H., et al. (2025) · PLoS ONE · doi:10.1371/journal.pone.0317944

DNA Methylation Status of Regulatory Regions of Apoptosis-Associated Genes in Dystropy «Huntington’s Disease—Non-Small Cell Lung Cancer»

Бабушкина, Н. П., Bragina, E. Y., Gomboeva, D. E., Koroleva, I. A., Illarioshkin, S. N., Klyushnikov, S. A., Abramycheva, N. Y., Никитина, М. А., Alifirova, V. M., Литвяков, Н. В., et al. (2025) · Epigenomes · doi:10.3390/epigenomes9030028

Differential diagnostics of non-small-cell and small-cell lung cancer: modern approaches and promising technologies

Konoshenko, M. Y., Shutko, E. V., Bryzgunova, O. E., Ilyushchenko, A. A., Danilova, Y. M., Gorbunkov, S. D., Zykov, K. A., & Laktionov, P. P. (2025) · Journal of clinical practice · doi:10.17816/clinpract688161

Exercise and Epigenetic Regulation in COPD: Current Evidence and Potential Mechanistic Pathways

Zhong, Y., Xu, J.-H., Chen, X., Lv, Y., & Zheng, X. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262311392 · Cited by 2

Considerations for study design and analysis for ethically and culturally safe DNA methylation research in Aotearoa New Zealand

Rolleston, A. K., Jones, G. T., Earle, N. J., Gibbs, S., Pilbrow, A. P., Faatoese, A. F., Poppe, K., Henare, K. L., Cameron, V. A., Macartney-Coxson, D. P., et al. (2025) · SSM - Population Health · doi:10.1016/j.ssmph.2025.101889

A timeless chronicle: Effects of cigarette smoke on GPR15 receptor and its oncogenic potential

Mathivanan, P., Raut, P., Gayen, N., Ganti, A. K., Ponnusamy, M. P., & Batra, S. K. (2025) · Cancer Letters · doi:10.1016/j.canlet.2025.218224

Additional file 7 of Leveraging biological and statistical covariates improves the detection power in epigenome-wide association testing

Huang, J., Bai, L., Cui, B., Wu, L., Wang, L., An, Z., Ruan, S., Yu, Y., Zhang, X., & Chen, J. (2020) · Figshare · doi:10.6084/m9.figshare.12097371

Additional file 1 of An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci

Logue, M. W., Miller, M. W., Wolf, E. J., Huber, B. R., Morrison, F. G., Zhou, Z., Zheng, Y., Smith, A. K., Daskalakis, N. P., Ratanatharathorn, A. D., et al. (2020) · Figshare · doi:10.6084/m9.figshare.11986023

Additional file 2 of A validated restriction enzyme ddPCR cg05575921 (AHRR) assay to accurately assess smoking exposure

Fitzgerald, S. J., Bhat, B., Print, C., & Jones, G. T. (2024) · Figshare · doi:10.6084/m9.figshare.25479074

Additional file 6 of No association between peripheral serotonin-gene-related DNA methylation and brain serotonin neurotransmission in the healthy and depressed state

Bruzzone, S. E. P., Ozenne, B., Fisher, P. M., Ortega, G., Jensen, P. S., Dam, V. H., Svarer, C., Knudsen, G. M., Lesch, K., & Frokjaer, V. G. (2024) · Figshare · doi:10.6084/m9.figshare.26726351

Additional file 8 of No association between peripheral serotonin-gene-related DNA methylation and brain serotonin neurotransmission in the healthy and depressed state

Bruzzone, S. E. P., Ozenne, B., Fisher, P. M., Ortega, G., Jensen, P. S., Dam, V. H., Svarer, C., Knudsen, G. M., Lesch, K., & Frokjaer, V. G. (2024) · Figshare · doi:10.6084/m9.figshare.26726357

Additional file 7 of No association between peripheral serotonin-gene-related DNA methylation and brain serotonin neurotransmission in the healthy and depressed state

Bruzzone, S. E. P., Ozenne, B., Fisher, P. M., Ortega, G., Jensen, P. S., Dam, V. H., Svarer, C., Knudsen, G. M., Lesch, K., & Frokjaer, V. G. (2024) · Figshare · doi:10.6084/m9.figshare.26726354

Additional file 3 of No association between peripheral serotonin-gene-related DNA methylation and brain serotonin neurotransmission in the healthy and depressed state

Bruzzone, S. E. P., Ozenne, B., Fisher, P. M., Ortega, G., Jensen, P. S., Dam, V. H., Svarer, C., Knudsen, G. M., Lesch, K., & Frokjaer, V. G. (2024) · Figshare · doi:10.6084/m9.figshare.26726342

Additional file 2 of From tobacco smoking to cancer mutational signature: a mediation analysis strategy to explore the role of epigenetic changes

Chen, Z., Wanqing, W., Cai, Q., Long, J., Wang, Y., Lin, W., Shu, X.-O., Zheng, W., & Guo, X. (2020) · Figshare · doi:10.6084/m9.figshare.12955303

Additional file 3 of From tobacco smoking to cancer mutational signature: a mediation analysis strategy to explore the role of epigenetic changes

Chen, Z., Wanqing, W., Cai, Q., Long, J., Wang, Y., Lin, W., Shu, X.-O., Zheng, W., & Guo, X. (2020) · Figshare · doi:10.6084/m9.figshare.12955306

Additional file 4 of From tobacco smoking to cancer mutational signature: a mediation analysis strategy to explore the role of epigenetic changes

Chen, Z., Wanqing, W., Cai, Q., Long, J., Wang, Y., Lin, W., Shu, X.-O., Zheng, W., & Guo, X. (2020) · Figshare · doi:10.6084/m9.figshare.12955309

Additional file 2 of Accelerated epigenetic age, inflammation, and gene expression in lung: comparisons of smokers and vapers with non-smokers

Song, M.-A., Mori, K. M., McElroy, J. P., Freudenheim, J. L., Weng, D. Y., Reisinger, S. A., Brasky, T. M., Wewers, M. D., & Shields, P. G. (2024) · Figshare · doi:10.6084/m9.figshare.24295767

Additional file 1 of The association between DNA methylation of 6p21.33 and AHRR in blood and coronary heart disease in Chinese population

Zhu, L., Zhu, C., Wang, J., Yang, R., & Zhao, X. (2022) · Figshare · doi:10.6084/m9.figshare.20486684

Additional file 5 of No association between peripheral serotonin-gene-related DNA methylation and brain serotonin neurotransmission in the healthy and depressed state

Bruzzone, S. E. P., Ozenne, B., Fisher, P. M., Ortega, G., Jensen, P. S., Dam, V. H., Svarer, C., Knudsen, G. M., Lesch, K., & Frokjaer, V. G. (2024) · Figshare · doi:10.6084/m9.figshare.26726348

Additional file 4 of No association between peripheral serotonin-gene-related DNA methylation and brain serotonin neurotransmission in the healthy and depressed state

Bruzzone, S. E. P., Ozenne, B., Fisher, P. M., Ortega, G., Jensen, P. S., Dam, V. H., Svarer, C., Knudsen, G. M., Lesch, K., & Frokjaer, V. G. (2024) · Figshare · doi:10.6084/m9.figshare.26726345

Additional file 1 of A variability in response of osteoclasts to zoledronic acid is mediated by smoking-associated modification in the DNA methylome

Tan, Q., Møller, A. M. J., Qiu, C., Madsen, J. S., Shen, H., Bechmann, T., Delaisse, J.-M., Kristensen, B. W., HongWen, D., Karasik, D., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22619369

Additional file 2 of No association between peripheral serotonin-gene-related DNA methylation and brain serotonin neurotransmission in the healthy and depressed state

Bruzzone, S. E. P., Ozenne, B., Fisher, P. M., Ortega, G., Jensen, P. S., Dam, V. H., Svarer, C., Knudsen, G. M., Lesch, K., & Frokjaer, V. G. (2024) · Figshare · doi:10.6084/m9.figshare.26726339

Additional file 1 of No association between peripheral serotonin-gene-related DNA methylation and brain serotonin neurotransmission in the healthy and depressed state

Bruzzone, S. E. P., Ozenne, B., Fisher, P. M., Ortega, G., Jensen, P. S., Dam, V. H., Svarer, C., Knudsen, G. M., Lesch, K., & Frokjaer, V. G. (2024) · Figshare · doi:10.6084/m9.figshare.26726336

Additional file 5 of From tobacco smoking to cancer mutational signature: a mediation analysis strategy to explore the role of epigenetic changes

Chen, Z., Wanqing, W., Cai, Q., Long, J., Wang, Y., Lin, W., Shu, X.-O., Zheng, W., & Guo, X. (2020) · Figshare · doi:10.6084/m9.figshare.12955312

Additional file 9 of No association between peripheral serotonin-gene-related DNA methylation and brain serotonin neurotransmission in the healthy and depressed state

Bruzzone, S. E. P., Ozenne, B., Fisher, P. M., Ortega, G., Jensen, P. S., Dam, V. H., Svarer, C., Knudsen, G. M., Lesch, K., & Frokjaer, V. G. (2024) · Figshare · doi:10.6084/m9.figshare.26726360

Additional file 6 of Leveraging biological and statistical covariates improves the detection power in epigenome-wide association testing

Huang, J., Bai, L., Cui, B., Wu, L., Wang, L., An, Z., Ruan, S., Yu, Y., Zhang, X., & Chen, J. (2020) · Figshare · doi:10.6084/m9.figshare.12097362

Additional file 1 of Refining epigenetic prediction of chronological and biological age

Bernabeu, E., McCartney, D. L., Gadd, D. A., Hillary, R. F., Lu, A. T., Murphy, L., Wrobel, N., Campbell, A., Harris, S. E., Liewald, D. C. M., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26571940

Additional file 2 of Refining epigenetic prediction of chronological and biological age

Bernabeu, E., McCartney, D. L., Gadd, D. A., Hillary, R. F., Lu, A. T., Murphy, L., Wrobel, N., Campbell, A., Harris, S. E., Liewald, D. C. M., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26571943

Additional file 3 of Refining epigenetic prediction of chronological and biological age

Bernabeu, E., McCartney, D. L., Gadd, D. A., Hillary, R. F., Lu, A. T., Murphy, L., Wrobel, N., Campbell, A., Harris, S. E., Liewald, D. C. M., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26571946

Additional file 1 of High-dimensional mediation analysis for continuous outcome with confounders using overlap weighting method in observational epigenetic study

Hu, W., Chen, S., Cai, J., Yang, Y., Yan, H., & Chen, F. (2024) · Figshare · doi:10.6084/m9.figshare.26728942

Additional file 1 of Accelerated epigenetic age, inflammation, and gene expression in lung: comparisons of smokers and vapers with non-smokers

Song, M.-A., Mori, K. M., McElroy, J. P., Freudenheim, J. L., Weng, D. Y., Reisinger, S. A., Brasky, T. M., Wewers, M. D., & Shields, P. G. (2023) · Figshare · doi:10.6084/m9.figshare.24295676

Additional file 1 of Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR

Scherer, M., Gasparoni, G., Rahmouni, S., Shashkova, T., Arnoux, M., Louis, E., Nostaeva, A., Avalos, D., Dermitzakis, E. T., Aulchenko, Y. S., et al. (2021) · Figshare · doi:10.6084/m9.figshare.16632876

Additional file 1 of Epigenetic prediction of complex traits and mortality in a cohort of individuals with oropharyngeal cancer

Langdon, R., Beynon, R. A., Ingarfield, K., Marioni, R. E., McCartney, D. L., Martin, R. M., Ness, A., Pawlita, M., Waterboer, T., Relton, C. L., et al. (2020) · Figshare · doi:10.6084/m9.figshare.12177885

Additional file 1: Table S1. of DNA methylation changes of whole blood cells in response to active smoking exposure in adults: a systematic review of DNA methylation studies

Gao, X., Jia, M., Zhang, Y., Breitling, L. P., & Brenner, H. (2015) · Figshare · doi:10.6084/m9.figshare.c.3626948_d1

REVIEW

(2016)

DNA methylation and smoking in Korean adults: epigenome-wide association study

Lee, M. K., Hong, Y., Kim, S., London, S. J., & Kim, W. J. (2016) · Clinical Epigenetics · doi:10.1186/s13148-016-0266-6 · Cited by 51

Abstract 3647: Dose-dependent alteration of CpG methylation in AHRR and GFI1 in mononuclear cell DNA of smokers.

Wang, X., Pittman, G. S., Su, D., Adamski, K. N., Campbell, M. R., Joubert, B. R., Huang, Z. Y., Hoyo, C., Murphy, S. K., London, S., et al. (2013) · Cancer Research · doi:10.1158/1538-7445.am2013-3647 · Cited by 1

Epigenome-450K-wide methylation signatures of active cigarette smoking: The Young Finns Study

Mishra, P. P., Hanninen, I., Raitoharju, E., Marttila, S., Mishra, B. H., Mononen, N., Kahonen, M., Hurme, M., Raitakari, O. T., Toronen, P., et al. (2022) · UTUPub (University of Turku)