The DOI matches its Crossref record; 156 of the 156 references it cites were found in a registry or an index.
Exosomes: biogenesis, biologic function and clinical potential
Open accessAbstract
Exosomes are nano-sized biovesicles released into surrounding body fluids upon fusion of multivesicular bodies and the plasma membrane. They were shown to carry cell-specific cargos of proteins, lipids, and genetic materials, and can be selectively taken up by neighboring or distant cells far from their release, reprogramming the recipient cells upon their bioactive compounds. Therefore, the regulated formation of exosomes, specific makeup of their cargo, cell-targeting specificity are of immense biological interest considering extremely high potential of exosomes as non-invasive diagnostic biomarkers, as well as therapeutic nanocarriers. In present review, we outline and discuss recent progress in the elucidation of the regulatory mechanisms of exosome biogenesis, the molecular composition of exosomes, and technologies used in exosome research. Furthermore, we focus on the potential use of exosomes as valuable diagnostic and prognostic biomarkers for their cell-lineage and state-specific contents, and possibilities as therapeutic vehicles for drug and gene delivery. Exosome research is now in its infancy, in-depth understanding of subcellular components and mechanisms involved in exosome formation and specific cell-targeting will bring light on their physiological activities.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Figures
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Exosomes originate from the endosomal pathway and are released by fusion of multivesicular bodies (MVBs) and plasma membranes, with sizes ranging from 30 to 150 nm [120, 121].”
From Extracellular vesicles as nanotheranostic platforms for targeted neurological disorder interventions (2024) · cites this paper as [120]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Zhang et al. reported that exosomes were crucial not only for cell-to-cell communications, but also for metabolic and cellular processes, and the regulation of biological processes [67].”
From Exosome-functionalized magnesium-organic framework-based scaffolds with osteogenic, angiogenic and anti-inflammatory properties for accelerated bone regeneration. (2022) · cites this paper as [67]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
2 retracted
Zhao, Y., Haney, M. J., Gupta, R., Bohnsack, J. P., He, Z., Kabanov, A. V., & Batrakova, E. V. (2014) · PLoS ONE · doi:10.1371/journal.pone.0106867 · Cited by 144
RetractedHaney, M. J., Zhao, Y., Harrison, E. B., Mahajan, V., Ahmed, S., He, Z., Suresh, P., Hingtgen, S., Klyachko, N. L., Mosley, R. L., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0061852 · Cited by 144
RetractedRepertoires of Autophagy in the Pathogenesis of Ocular Diseases
Li, Y., Jiang, Q. L., Cao, G.-F., Yao, J., & Yan, B. (2015) · Cellular Physiology and Biochemistry · doi:10.1159/000373980 · Cited by 16,351
Valadi, H., Ekström, K., Bossios, A., Sjöstrand, M., Lee, J. J., & Lötvall, J. O. (2007) · Nature Cell Biology · doi:10.1038/ncb1596 · Cited by 12,834
Isolation and Characterization of Exosomes from Cell Culture Supernatants and Biological Fluids
Théry, C., Amigorena, S., Raposo, G., & Clayton, A. (2006) · Current Protocols in Cell Biology · doi:10.1002/0471143030.cb0322s30 · Cited by 5,766
Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
Alvarez-Erviti, L., Seow, Y., Yin, H., Betts, C., Lakhal, S., & Wood, M. J. A. (2011) · Nature Biotechnology · doi:10.1038/nbt.1807 · Cited by 4,930
The future of immune checkpoint therapy
Sharma, P., & Allison, J. P. (2015) · Science · doi:10.1126/science.aaa8172 · Cited by 4,878
Evidence for the Formation of Symmetric and Asymmetric DLPC-DAPC Lipid Bilayer Domains
Ritter, M., Schmidt, S., Jakab, M., Paulmichl, M., & Henderson, R. M. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350122 · Cited by 3,923
Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes
Trajković, K., Hsu, C., Chiantia, S., Rajendran, L., Wenzel, D., Wieland, F., Schwille, P., Brügger, B., & Simons, M. (2008) · Science · doi:10.1126/science.1153124 · Cited by 3,760
B lymphocytes secrete antigen-presenting vesicles.
Raposo, G., Nijman, H. W., Stoorvogel, W., Liejendekker, R., Harding, C. V., Melief, C. J., & Geuze, H. J. (1996) · The Journal of experimental medicine · doi:10.1084/jem.183.3.1161 · Cited by 3,546
Cited by
Sorted by citations
Items 801–900 of 1,001
Critical Challenges and Future Direction in Extracellular Vesicle Research and Commercialization
Park, S. J., & Jung, H. (2025) · BioChip Journal · doi:10.1007/s13206-025-00232-z · Cited by 21
Li, S., Han, H., Yang, K., Li, X., Ma, L., Yang, Z. R., & Zhao, Y. (2025) · Molecular Cancer · doi:10.1186/s12943-025-02470-z · Cited by 21
Giannecchini, S. (2020) · Viruses · doi:10.3390/v12060585 · Cited by 21
Liu, Y., Su, C., Yan, Y., Wang, J., Li, J., Fu, J., Wang, Y., & Zhang, J. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.926769 · Cited by 21
Self-citationExosomes as Novel Delivery Systems for Application in Traditional Chinese Medicine
Chen, Q., Wu, D., Wang, Y., & Chen, Z. (2022) · Molecules · doi:10.3390/molecules27227789 · Cited by 21
Exosomes in chronic liver disease
Mohan, P. B., Rajpurohit, S., Musunuri, B., Bhat, G., Lochan, R., & Shetty, S. (2023) · Clinica Chimica Acta · doi:10.1016/j.cca.2022.117215 · Cited by 21
Xie, L., Zhang, K., You, B., Yin, H., Zhang, P., Shan, Y., Gu, Z., & Zhang, Q. (2023) · Molecular Carcinogenesis · doi:10.1002/mc.23525 · Cited by 21
Han, J. M., Song, H.-Y., Jung, J., Lim, S., Seo, H. S., Kim, W. S., Lim, S.-T., & Byun, E. (2023) · Biological Procedures Online · doi:10.1186/s12575-023-00211-4 · Cited by 21
Ribeiro, J., Lopes, I., & Gomes, A. C. (2023) · Molecules · doi:10.3390/molecules28166015 · Cited by 21
Zhou, Y. L., Dong, Y., Zhang, A., Wu, J., & Sun, Q. (2023) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2023.1214190 · Cited by 21
Current progress and prospect of microfluidic-based exosome investigation
Wang, Y., Bao, Y., Liang, Y.-X., Chen, Y.-J., Huang, W., & Xie, M. (2023) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2023.117310 · Cited by 21
Zhuang, M., Rao, L., Chen, Y., Xiao, S., Xia, H., Yang, J., Lv, X., Qin, D., & Zhu, C. (2023) · International Journal of Nanomedicine · doi:10.2147/ijn.s422416 · Cited by 21
Mesenchymal Stem Cell-Derived Exosomes and Their MicroRNAs in Heart Repair and Regeneration
Akbar, N., Razzaq, S. S., Salim, A., & Haneef, K. (2023) · Journal of Cardiovascular Translational Research · doi:10.1007/s12265-023-10449-8 · Cited by 21
Zhang, Z., Shi, C., & Wang, Z. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1279469 · Cited by 21
Multi-Omics Analysis of Circulating Exosomes in Adherent Long-Term Treated OSA Patients
Khalyfa, A., Marín, J. M., Sánz-Rubio, D., Lyu, Z., Joshi, T., & Gozal, D. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242216074 · Cited by 21
Exosomes as new generation vehicles for drug delivery systems
Dilsiz, N. (2024) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2024.105562 · Cited by 21
Fluorescent Chiral Quantum Dots to Unveil Origin-Dependent Exosome Uptake and Cargo Release
Kim, G., Zhu, R., Zhang, Y., Jeon, H., Shirinichi, F., & Wang, Y. (2024) · ACS Applied Bio Materials · doi:10.1021/acsabm.4c00296 · Cited by 22
Self-citationYi, S., Kim, M. J., Kim, M. J., Yae, C. G., Kim, K. H., & Kim, H. K. (2024) · The Ocular Surface · doi:10.1016/j.jtos.2024.09.006 · Cited by 21
Wang, X., Wang, J., Mao, L., & Yao, Y. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1512935 · Cited by 21
Recent theranostic paradigms for the management of Age-related macular degeneration
Suri, R., Neupane, Y. R., Jain, G. K., & Kohli, K. (2020) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2020.105489 · Cited by 21
The Role(s) of Eicosanoids and Exosomes in Human Parturition
Mosaad, E. M. O., Peiris, H. N., Holland, O. J., Garcia, I. M., & Mitchell, M. D. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.594313 · Cited by 21
Atipimonpat, A., Siwaponanan, P., Khuhapinant, A., Svasti, S., Sukapirom, K., Khowawisetsut, L., & Pattanapanyasat, K. (2021) · Annals of Hematology · doi:10.1007/s00277-021-04567-z · Cited by 21
Pro-angiogenic effect of PC-3 exosomes in endothelial cells in vitro
Prigol, A. N., Rode, M. P., Silva, A. H., Cisilotto, J., & Creczynski‐Pasa, T. B. (2021) · Cellular Signalling · doi:10.1016/j.cellsig.2021.110126 · Cited by 21
Current perspectives on clinical use of exosomes as novel biomarkers for cancer diagnosis
Yi, X., Chen, J., Huang, D., Feng, S., Yang, T., Li, Z., Wang, X., Zhao, M., Wu, J., & Zhong, T. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.966981 · Cited by 21
Exosomes in bone remodeling and breast cancer bone metastasis
Murari, L. S. S., Krishnan, R., Akshaya, R. L., Das, U. R., Satishkumar, S., & Selvamurugan, N. (2022) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2022.09.008 · Cited by 21
Development and Characterization of Bioinspired Lipid Raft Nanovesicles for Therapeutic Applications
Ramasubramanian, L., Jyothi, H., Goldbloom‐Helzner, L., Light, B. M., Kumar, P., Carney, R. P., Farmer, D. L., & Wang, A. (2022) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.2c13868 · Cited by 21
Han, J., Chang, H., Yang, J., Choi, H., Park, H., Jun, H., Choi, J., Paik, S.-S., Chung, K., Shin, H., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241512068 · Cited by 20
Conkright, W. R., Beckner, M. E., Sahu, A., Mi, Q., Clemens, Z. J., Lovalekar, M. T., Flanagan, S. D., Martin, B. J., Ferrarelli, F., Ambrosio, F., et al. (2022) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00664.2021 · Cited by 20
Mousavi, S. M., Hashemi, S. A., Gholami, A., Kalashgrani, M. Y., Rao, N. V., Omidifar, N., Hsiao, W. W., Lai, C. W., & Chiang, W. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14051054 · Cited by 20
Hoang, V. T., Nguyen, H.-P., Nguyen, V. N., Hoang, D. M., Nguyen, T.-S. T., & Thanh, L. N. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.956274 · Cited by 20
Integrins are enriched on aberrantly fucosylated tumour‐derived urinary extracellular vesicles
Islam, M. K., Dhondt, B., Syed, P., Khan, M., Gidwani, K., Webber, J. P., Hendrix, A., Jenster, G. W., Lamminen, T., Boström, P. J., et al. (2022) · Journal of Extracellular Biology · doi:10.1002/jex2.64 · Cited by 20
Extracellular Vesicles’ Role in the Pathophysiology and as Biomarkers in Cystic Fibrosis and COPD
Gioia, S. D., Daniello, V., & Conese, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms24010228 · Cited by 20
Exosomes: from biology to immunotherapy in infectious diseases
Rangel-Ramírez, V. V., González-Sánchez, H. M., & Lucio-García, C. (2022) · Scandinavian Journal of Infectious Diseases · doi:10.1080/23744235.2022.2149852 · Cited by 20
Chen, P., Gu, M., Wan, S., Jiang, X., Zhang, F., Li, Y., Zhou, Q., Lu, Y., Li, L., & Wang, X. (2023) · International Journal of Nanomedicine · doi:10.2147/ijn.s396194 · Cited by 20
Senescence-associated exosomes transfer miRNA-induced fibrosis to neighboring cells
Lee, A. H., Ghosh, D., Koh, I. L., & Dawson, M. (2023) · Aging · doi:10.18632/aging.204539 · Cited by 20
Lee, E. S., Ko, H., Kim, C. H., Kim, H.-C., Choi, S., Jeong, S. W., Lee, S.-G., Lee, S., Na, H., Park, J. H., et al. (2023) · Biomaterials Research · doi:10.1186/s40824-023-00418-2 · Cited by 20
Xue, C., Ma, X., Guan, X., Feng, H., Zheng, M., & Yang, X. (2023) · PeerJ · doi:10.7717/peerj.16311 · Cited by 20
Marassi, V., Giordani, S., Placci, A., Punzo, A., Caliceti, C., Zattoni, A., Reschiglian, P., Roda, B., & Roda, A. (2023) · Sensors · doi:10.3390/s23239432 · Cited by 20
Macrophages polarization in renal inflammation and fibrosis animal models (Review)
Zeng, J., Zhang, Y., & Huang, C. (2023) · Molecular Medicine Reports · doi:10.3892/mmr.2023.13152 · Cited by 22
Self-citationThe plasma derived exosomal miRNA-483-5p/502-5p serve as potential MCI biomarkers in aging
Liu, T., Li, N., Pu, J., Zhang, C., Xu, K., Wang, W., Liu, L., Gao, L., Xu, X., & Tan, J. (2024) · Experimental Gerontology · doi:10.1016/j.exger.2023.112355 · Cited by 20
Li, Y., Zhou, C., Liu, H., Cai, T., & Fan, H. (2024) · Biomolecules · doi:10.3390/biom14030312 · Cited by 20
Self-citationMorales-Primo, A. U., Becker, I., Zamora, C., & Zamora‐Chimal, J. (2024) · Immune Network · doi:10.4110/in.2024.24.e14 · Cited by 20
Current strategies using 3D organoids to establish in vitro maternal-embryonic interaction
Saadeldin, I. M., Ehab, S., Noreldin, A. E., Swelum, A. A., Bang, S., Kim, H. J., Yoon, K.-Y., Lee, S., & Cho, J. (2024) · Journal of Veterinary Science · doi:10.4142/jvs.24004 · Cited by 20
Ali, H., Malik, M. Z., Abu‐Farha, M., Abubaker, J. A., Cherian, P., Al‐Khairi, I., Nizam, R., Jacob, S. P., Bahbahani, Y., Alattar, A., et al. (2024) · Journal of the Endocrine Society · doi:10.1210/jendso/bvae114 · Cited by 20
Therapeutic and diagnostic applications of exosomes in colorectal cancer
Shakerian, N., Eslam, E. D., Afsharnoori, F., Bana, N., ghahroodi, F. N., Tarin, M., Mard‐Soltani, M., Khalesi, B., Hashemi, Z. S., & Khalili, S. (2024) · Medical Oncology · doi:10.1007/s12032-024-02440-3 · Cited by 21
Yun, J. H., Lee, H., Yeou, S. H., Jang, J. Y., Kim, C.-H., Shin, Y. S., & DʼLima, D. D. (2024) · Materials Today Bio · doi:10.1016/j.mtbio.2024.101283 · Cited by 20
Dhiman, A., Rana, D., Benival, D. M., & Garkhal, K. (2024) · Therapeutic Delivery · doi:10.1080/20415990.2024.2415281 · Cited by 20
Shi, Y., Wei, J., Nie, Y., Luo, J., Chen, T., Xi, Q., Zhang, Y., & Sun, J. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.138470 · Cited by 20
Self-citationSmall Extracellular Vesicles and Metastasis—Blame the Messenger
Seibold, T., Waldenmaier, M., Seufferlein, T. T. W., & Eiseler, T. (2021) · Cancers · doi:10.3390/cancers13174380 · Cited by 20
Adenosinergic Signaling as a Key Modulator of the Glioma Microenvironment and Reactive Astrocytes
Debom, G. N., Rubenich, D. S., & Braganhol, E. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.648476 · Cited by 20
Zavala, G., Ramos, M.-P., Figueroa‐Valdés, A. I., Cisternas, P., Wyneken, Ú., Hernández, M., Toa, P., Salmons, B., Dangerfield, J. A., Günzburg, W. H., et al. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00679 · Cited by 20
Alharbi, M. G., Lai, A., Godbole, N., Guanzon, D., Nair, S., Zuñiga, F. A., Quinn, A., Yang, M., Wu, S. Y., & Salomón, C. (2024) · International Journal of Cancer · doi:10.1002/ijc.35055 · Cited by 19
Metabolic features of tumor-derived extracellular vesicles: challenges and opportunities
Espiau-Romera, P., Gordo-Ortiz, A., Ortiz-de-Solórzano, I., & Sancho, P. (2024) · Extracellular Vesicles and Circulating Nucleic Acids · doi:10.20517/evcna.2024.12 · Cited by 19
Engineered exosomes: a promising approach for overcoming challenges in pancreatic cancer therapy
Sha, M., Gao, Y., Xu, Y., Li, X., Liu, C., & Li, S. (2025) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-03697-0 · Cited by 19
Pulmonary involvement in systemic sclerosis: exploring cellular, genetic and epigenetic mechanisms
Doskaliuk, B., Zaiats, L., Yatsyshyn, R., Gerych, P., Cherniuk, N., & Zimba, O. (2020) · Rheumatology International · doi:10.1007/s00296-020-04658-6 · Cited by 19
Sanaee, M., Sandberg, E., Ronquist, G. K., Morrell, J. M., Widengren, J., & Gallo, K. (2022) · Small · doi:10.1002/smll.202106241 · Cited by 19
Concise review: Current understanding of extracellular vesicles to treat neuropathic pain
Zhang, K., Li, P., Jia, Y., Liu, M., & Jiang, J. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2023.1131536 · Cited by 19
Ferlizza, E., Romaniello, D., Borrelli, F., Pagano, F., Girone, C., Gelfo, V., Kuhre, R. S., Morselli, A., Mazzeschi, M., Sgarzi, M., et al. (2023) · Cancers · doi:10.3390/cancers15112970 · Cited by 19
Exosome-mediated renal protection: Halting the progression of fibrosis
Liu, C., Li, Q., Ma, J., Lu, B., Criswell, T. L., & Zhang, Y. (2023) · Genes & Diseases · doi:10.1016/j.gendis.2023.101117 · Cited by 19
Self-citationMendes, M., Monteiro, A. C., Neto, E., Barrias, C. C., Simões, M. S., Duarte, D., & Caires, H. R. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25084430 · Cited by 19
Alshahrani, M. Y., Jasim, S. A., Altalbawy, F. M. A., Bansal, P., Kaur, H., Al‐Hamdani, M. M., Deorari, M., Abosaoda, M. K., Hamzah, H. F., & Mohammed, B. A. (2024) · Cell Biochemistry and Function · doi:10.1002/cbf.4029 · Cited by 19
Therapeutic potential of mesenchymal stem cell-derived exosomes in skeletal diseases
Yang, X., Zhang, S., Lu, J., Chen, X., Zheng, T., He, R., Ye, C., & Xu, J. (2024) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2024.1268019 · Cited by 19
Cheng, W., Ren, W., Ye, P., Li, H., Bao, D., Yue, T., Lai, J., Wu, Y., Wei, Y., Wu, Z., et al. (2024) · Biomaterials · doi:10.1016/j.biomaterials.2024.122702 · Cited by 19
Stress-Related Roles of Exosomes and Exosomal miRNAs in Common Neuropsychiatric Disorders
Chamakioti, M., Chrousos, G. P., Kassi, E. N., Vlachakis, D., & Yapijakis, C. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25158256 · Cited by 19
Grenhas, M., Lopes, R., Ferreira, B. V., Barahona, F., Joao, C. M., & Carneiro, E. A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25158496 · Cited by 19
Sechi, G., & Sechi, M. M. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252011198 · Cited by 19
New insights into the immunomodulatory role of exosomes in cardiovascular disease
Jiang, W., & Wang, M. (2019) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm.2019.03.528 · Cited by 19
Differential proteomics analysis of serum exosomein burn patients
Qin, D., Yang, W., Pan, Z., Zhang, Y., Li, X., & Lakshmanan, S. (2020) · Saudi Journal of Biological Sciences · doi:10.1016/j.sjbs.2020.06.024 · Cited by 19
Self-citationExosomal MicroRNAs in Pregnancy Provides Insight into a Possible Cure for Cancer
Pillay, P., Moodley, K., Vatish, M., & Moodley, J. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21155384 · Cited by 19
An Overview of Exosomes in Cancer Therapy: A Small Solution to a Big Problem
Rodrigues, P., Melim, C., Veiga, F., & Figueiras, A. (2020) · Processes · doi:10.3390/pr8121561 · Cited by 19
Schönleinstrasse 2, 8. Z., Ivica, A., Zehnder, M., & Weber, F. E. (2021) · European Cells and Materials · doi:10.22203/ecm.v041a17 · Cited by 19
Evaluation of exosome derivatives as bio-informational reprogramming therapy for cancer
González, M. J., Kweh, M. F., Biava, P. M., Olalde, J., Toro, A. P., Goldschmidt‐Clermont, P. J., & White, I. A. (2021) · Journal of Translational Medicine · doi:10.1186/s12967-021-02768-8 · Cited by 19
Anand, K., Vadivalagan, C., Joseph, J. S., Singh, S. K., Gulati, M., Shahbaaz, M., Abdellattif, M. H., Prasher, P., Gupta, G., Chellappan, D. K., et al. (2021) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2021.109497 · Cited by 19
Ayala‐Ramírez, P., Machuca-Acevedo, C., Gámez, T., Quijano, S., Barreto, A., Silva, J. L., Olaya, M., & García‐Robles, R. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.708824 · Cited by 19
Roles of Non-Coding RNAs as Novel Diagnostic Biomarkers in Parkinson’s Disease
Manna, I., Quattrone, A., Benedittis, S. D., Iaccino, E., & Quattrone, A. (2021) · Journal of Parkinson s Disease · doi:10.3233/jpd-212726 · Cited by 19
Desai, C. S., Khan, A., Bellio, M. A., Willis, M. L., Mahung, C., Ma, X., Baldwin, X. L., Williams, B. M., Baron, T. H., Coleman, L. G., et al. (2021) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-021-04248-5 · Cited by 19
The Role of Non-Immune Cell-Derived Extracellular Vesicles in Allergy
Hovhannisyan, L. P., Czechowska, E., & Gutowska‐Owsiak, D. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.702381 · Cited by 20
Dubey, A., Lobo, C. L., gs, R., Shetty, A., Hebbar, S., & El‐Zahaby, S. A. (2021) · Asian Journal of Pharmaceutical Sciences · doi:10.1016/j.ajps.2021.08.004 · Cited by 19
Immunomodulatory Actions of Mesenchymal Stromal Cells (MSCs) in Osteoarthritis of the Knee
Babu, G. S., Badrish, Y., Oswal, V. M., Jeyaraman, N., Prajwal, G. S., Jeyaraman, M., Muthu, S., & Khanna, M. (2021) · Osteology · doi:10.3390/osteology1040020 · Cited by 19
Strohmeier, K., Hofmann, M., Hauser, F., Sivun, D., Puthukodan, S., Karner, A., Sandner, G., Renard, P. L., Jacak, J., & Mairhofer, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms23010282 · Cited by 19
Therapeutic properties of stem cell-derived exosomes in ischemic heart disease
Raissi-Dehkordi, N., Raissi-Dehkordi, N., & Farjoo, M. H. (2022) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2022.174839 · Cited by 19
Stem Cell Homing in Intrathecal Applications and Inspirations for Improvement Paths
Maric, D. M., Velikic, G. S., Marić, D., Šupić, G., Vojvodić, D., Petrić, V., & Abazović, D. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23084290 · Cited by 19
Kumar, S. K., & Manda, S. V. (2023) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.3c00363 · Cited by 19
Liposomes embedded in layer by layer constructs as simplistic extracellular vesicles transfer model
Domínguez-Arca, V., Costa, R. R., Carvalho, A. M., Taboada, P., Reis, R. L., Prieto, G., & Pashkuleva, I. (2020) · Materials Science and Engineering C · doi:10.1016/j.msec.2020.111813 · Cited by 19
Li, H., Yang, Y., Gao, Y., Li, B., Yang, J., Liu, P., Zhang, M., & Ning, G. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-06808-5 · Cited by 18
Cancer-derived exosomes: mediators of immune crosstalk and emerging targets for immunotherapy
Mahamed, R., Monchusi, B. A., Penny, C. B., & Mirza, S. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1679934 · Cited by 18
Babaei, G., Vostakolaei, M. A., Bazl, M. R., Aziz, S. G., Gholipour, E., & Nejati‐Koshki, K. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.121103 · Cited by 18
Noori, L., Filip, K., Nazmara, Z., Mahakizadeh, S., Hassanzadeh, G., Bavisotto, C. C., Bucchieri, F., Marino, A., Cappello, F., Wnuk, M., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24020927 · Cited by 18
Karagür, E. R., Demiray, A., Karagenç, N., Elver, E., Tokgün, O., Yaren, A., Doğu, G. G., & Akça, H. (2023) · Genetika · doi:10.2298/gensr2301083k · Cited by 18
Peng, X., Zhang, T., Liu, R., & Jin, X. (2023) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-023-04798-w · Cited by 18
Moghaddam, M. M., Fazel, P., Fallah, A., Sedighian, H., Kachuei, R., Behzadi, E., & Fooladi, A. A. I. (2023) · Stem Cell Reviews and Reports · doi:10.1007/s12015-023-10594-2 · Cited by 18
Exosome-biomimetic nanocarriers for oral drug delivery
Liu, F., Meng, F., Yang, Z., Wang, H., Ren, Y., Cai, Y., & Zhang, X. (2023) · Chinese Chemical Letters · doi:10.1016/j.cclet.2023.109335 · Cited by 18
Bir, A., Ghosh, A., Chauhan, A., Saha, S., Saini, A. K., Bisaglia, M., & Chakrabarti, S. (2024) · Antioxidants · doi:10.3390/antiox13030316 · Cited by 18
Wang, M., Sun, Y., Gu, R. C., Tang, Y., Han, G., & Zhao, S. (2024) · Journal of Ovarian Research · doi:10.1186/s13048-024-01430-3 · Cited by 18
Hodgkin lymphoma and liquid biopsy: a story to be told
Velasco-Suelto, J., Gálvez, L., Comino‐Méndez, I., & Rueda‐Domínguez, A. (2024) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-024-03108-6 · Cited by 18
Pir, G. J., Zahid, M., Akhtar, N., Ayadathil, R., Pananchikkal, S. V., Joseph, S., Morgan, D. M., Babu, B. M., Ui, R. T., Sivasankaran, S., et al. (2024) · Brain Research · doi:10.1016/j.brainres.2024.149171 · Cited by 18
Zhang, Y., Zhang, C., Wu, N., Feng, Y., Wang, J., Ma, L., & Chen, Y. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1473030 · Cited by 18
Self-citationUnveiling exosomes: Cutting‐edge isolation techniques and their therapeutic potential
Sani, F., Shafiei, F., Dehghani, F., Mohammadi, Y., Khorraminejad‐Shirazi, M., Anvari‐Yazdi, A. F., Moayedfard, Z., Azarpira, N., & Sani, M. (2024) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.70139 · Cited by 18
Exosomes as a Therapeutic Strategy in Cancer: Potential Roles as Drug Carriers and Immune Modulators
Abedi, A., Moghaddam, M. M., Kachuei, R., & Fooladi, A. A. I. (2024) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2024.189238 · Cited by 18
Vosoughi, P., Naghib, S. M., Jafari, T., & Kangarshahi, B. M. (2025) · Carbohydrate Polymer Technologies and Applications · doi:10.1016/j.carpta.2025.100805 · Cited by 17
Metadata
- Authors
- Zhang, Y., Liu, Y., Liu, H., & Tang, W. H.
- Affiliations
- Guangzhou Women and Children Medical Center (CN)
- Corresponding author
- Liu, Haiying
- Tang, Wai Ho
- Venue
- Cell & Bioscience
- Published
- 2019-02-15
- Volume
- 9
- Issue
- 1
- Pages
- 19-19
- ISSN
- 2045-3701 (ISSN-L)
- PMC
- PMC6377728
- OpenAlex
- W2931418311
- Cited by
- 2,119
- References
- 156
- Citations by year
- 2026: 203 · 2025: 327 · 2024: 386 · 2023: 361 · 2022: 334 · 2021: 297 · 2020: 184 · 2019: 24
- FWCI
- 18.57
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Cell & Bioscience (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, other-oa)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Extracellular vesicles in disease
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular transport and secretion
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Keywords
- exosomes, exosome biogenesis, multivesicular bodies, exosome cargo, exosome uptake, cell targeting, diagnostic biomarkers, prognostic factors, drug delivery, gene delivery, extracellular vesicles
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
