The DOI matches its Crossref record; 156 of the 156 references it cites were found in a registry or an index.
Exosomes: biogenesis, biologic function and clinical potential
Open accessAbstract
Exosomes are nano-sized biovesicles released into surrounding body fluids upon fusion of multivesicular bodies and the plasma membrane. They were shown to carry cell-specific cargos of proteins, lipids, and genetic materials, and can be selectively taken up by neighboring or distant cells far from their release, reprogramming the recipient cells upon their bioactive compounds. Therefore, the regulated formation of exosomes, specific makeup of their cargo, cell-targeting specificity are of immense biological interest considering extremely high potential of exosomes as non-invasive diagnostic biomarkers, as well as therapeutic nanocarriers. In present review, we outline and discuss recent progress in the elucidation of the regulatory mechanisms of exosome biogenesis, the molecular composition of exosomes, and technologies used in exosome research. Furthermore, we focus on the potential use of exosomes as valuable diagnostic and prognostic biomarkers for their cell-lineage and state-specific contents, and possibilities as therapeutic vehicles for drug and gene delivery. Exosome research is now in its infancy, in-depth understanding of subcellular components and mechanisms involved in exosome formation and specific cell-targeting will bring light on their physiological activities.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Figures
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Exosomes originate from the endosomal pathway and are released by fusion of multivesicular bodies (MVBs) and plasma membranes, with sizes ranging from 30 to 150 nm [120, 121].”
From Extracellular vesicles as nanotheranostic platforms for targeted neurological disorder interventions (2024) · cites this paper as [120]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Zhang et al. reported that exosomes were crucial not only for cell-to-cell communications, but also for metabolic and cellular processes, and the regulation of biological processes [67].”
From Exosome-functionalized magnesium-organic framework-based scaffolds with osteogenic, angiogenic and anti-inflammatory properties for accelerated bone regeneration. (2022) · cites this paper as [67]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
2 retracted
Zhao, Y., Haney, M. J., Gupta, R., Bohnsack, J. P., He, Z., Kabanov, A. V., & Batrakova, E. V. (2014) · PLoS ONE · doi:10.1371/journal.pone.0106867 · Cited by 144
RetractedHaney, M. J., Zhao, Y., Harrison, E. B., Mahajan, V., Ahmed, S., He, Z., Suresh, P., Hingtgen, S., Klyachko, N. L., Mosley, R. L., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0061852 · Cited by 144
RetractedRepertoires of Autophagy in the Pathogenesis of Ocular Diseases
Li, Y., Jiang, Q. L., Cao, G.-F., Yao, J., & Yan, B. (2015) · Cellular Physiology and Biochemistry · doi:10.1159/000373980 · Cited by 16,351
Valadi, H., Ekström, K., Bossios, A., Sjöstrand, M., Lee, J. J., & Lötvall, J. O. (2007) · Nature Cell Biology · doi:10.1038/ncb1596 · Cited by 12,834
Isolation and Characterization of Exosomes from Cell Culture Supernatants and Biological Fluids
Théry, C., Amigorena, S., Raposo, G., & Clayton, A. (2006) · Current Protocols in Cell Biology · doi:10.1002/0471143030.cb0322s30 · Cited by 5,766
Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
Alvarez-Erviti, L., Seow, Y., Yin, H., Betts, C., Lakhal, S., & Wood, M. J. A. (2011) · Nature Biotechnology · doi:10.1038/nbt.1807 · Cited by 4,930
The future of immune checkpoint therapy
Sharma, P., & Allison, J. P. (2015) · Science · doi:10.1126/science.aaa8172 · Cited by 4,878
Evidence for the Formation of Symmetric and Asymmetric DLPC-DAPC Lipid Bilayer Domains
Ritter, M., Schmidt, S., Jakab, M., Paulmichl, M., & Henderson, R. M. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350122 · Cited by 3,923
Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes
Trajković, K., Hsu, C., Chiantia, S., Rajendran, L., Wenzel, D., Wieland, F., Schwille, P., Brügger, B., & Simons, M. (2008) · Science · doi:10.1126/science.1153124 · Cited by 3,760
B lymphocytes secrete antigen-presenting vesicles.
Raposo, G., Nijman, H. W., Stoorvogel, W., Liejendekker, R., Harding, C. V., Melief, C. J., & Geuze, H. J. (1996) · The Journal of experimental medicine · doi:10.1084/jem.183.3.1161 · Cited by 3,546
Cited by
Sorted by citations
Items 701–800 of 1,001
Lee, H.-I., Ahn, M.-J., Yoo, J., Ahn, S., Park, S. Y., Seo, H., Kim, M., Lee, Y. J., Jang, H. H., Shim, S. C., et al. (2024) · Arthritis Research & Therapy · doi:10.1186/s13075-023-03225-1 · Cited by 26
Landscape of exosomes to modified exosomes: a state of the art in cancer therapy
Mirgh, D., Sonar, S., Ghosh, S., Adhikari, M. D., Subramaniyan, V., Gorai, S., & Anand, K. (2024) · RSC Advances · doi:10.1039/d4ra04512b · Cited by 26
Shedding Light on the Role of Extracellular Vesicles in HIV Infection and Wound Healing
Alqatawni, A., Sharma, A. L., Attilus, B., Tyagi, M., & Daniel, R. (2020) · Viruses · doi:10.3390/v12060584 · Cited by 26
Norouzi‐Barough, L., Shirian, S., Gorji, A., & Sadeghi, M. T. (2021) · Connective Tissue Research · doi:10.1080/03008207.2021.1887855 · Cited by 26
Niu, L., Wang, Q., Feng, F., Yang, W., Xie, Z., Zheng, G., Zhou, W., Duan, L., Du, K., Li, Y., et al. (2023) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2023.166917 · Cited by 25
Bone aging and extracellular vesicles
Wang, J., Zhang, Y., Wang, S., Wang, X., Jing, Y., & Su, J. (2024) · 中国科学通报：英文版 · doi:10.1016/j.scib.2024.10.013 · Cited by 25
Self-citationMehta, M. J., Shin, D., Park, H. S., An, J., Lim, S. I., Kim, H. J., Hong, S., & Bu, J. (2025) · Small Methods · doi:10.1002/smtd.202402058 · Cited by 25
Stem cell derived exosome trilogy: an epic comparison of human MSCs, ESCs and iPSCs
Malik, S. A., Muhilan, Y., Nordin, F., Ng, M. H., Law, J. X., Imran, S. A. M., Idris, I. M., & Tye, G. J. (2025) · Stem Cell Research & Therapy · doi:10.1186/s13287-025-04440-0 · Cited by 25
Rahgoshay, M., Atashi, A., Vaezi, M., Ajorloo, M., Amini‐Kafiabad, S., & Ahmadvand, M. (2025) · Cancer Nanotechnology · doi:10.1186/s12645-025-00334-1 · Cited by 25
Ju, J., Neuen, S. M. L., van Zandvoort, M. A. M. J., Keulers, T. G., & Rouschop, K. M. A. (2025) · Extracellular Vesicles and Circulating Nucleic Acids · doi:10.20517/evcna.2025.21 · Cited by 25
Primorac, D., Brlek, P., Bulić, L., Hrvatin, N., Škaro, V., Projić, P., Glavan, M., Oleru, I., Rocheteau, P., Tremolada, C., et al. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27041676 · Cited by 25
Hyung, S., Jeong, J., Shin, K., Kim, J. Y., Yim, J., Yu, C. J., Jung, H. S., Hwang, K., Choi, D., & Hong, J. W. (2020) · Biotechnology and Bioengineering · doi:10.1002/bit.27447 · Cited by 25
Bark, J. M., Kulasinghe, A., Amenábar, J. M., & Punyadeera, C. (2020) · Advances in clinical chemistry · doi:10.1016/bs.acc.2020.06.006 · Cited by 25
Exosomal Components and Modulators in Colorectal Cancer: Novel Diagnosis and Prognosis Biomarkers
Chang, Y., Chan, M., Li, C., Fang, C., Hsiao, M., & Chen, C. (2021) · Biomedicines · doi:10.3390/biomedicines9080931 · Cited by 25
Microfluidic Platforms to Unravel Mysteries of Alzheimer’s Disease: How Far Have We Come?
Prasanna, P., Rathee, S., Rahul, V., Mandal, D., Goud, M. S. C., Yadav, P., Hawthorne, S. J., Sharma, A., Gupta, P. K., Ojha, S. K., et al. (2021) · Life · doi:10.3390/life11101022 · Cited by 25
Shen, M., & Chen, T. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/4539453 · Cited by 25
RetractedSingh, R., Zogg, H., & Ro, S. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11101021 · Cited by 25
Sun, F., Geng, H., Sun, Y., Feng, W., Tian, T., Ye, L., & Lei, M. (2022) · Molecular Medicine Reports · doi:10.3892/mmr.2022.12635 · Cited by 25
Guedes, V. A., Lange, R. T., Lippa, S. M., Lai, C., Greer, K., Mithani, S., Devoto, C., Edwards, K. A., Wagner, C. L., Martin, C. A., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-05772-0 · Cited by 25
Recent advances of non-coding RNAs in ovarian cancer prognosis and therapeutics
Chen, M., Lei, N., Tian, W., Li, Y., & Chang, L. (2022) · Therapeutic Advances in Medical Oncology · doi:10.1177/17588359221118010 · Cited by 25
Stem cell-derived exosomes in bone healing: focusing on their role in angiogenesis
Irfan, D., Ahmad, I. S., Patra, I., Margiana, R., Турсуналиевна, Р. М., Sivaraman, R., Kandeel, M. K., Mohammad, H. J., Al‐qaim, Z. H., Jawad, M. A., et al. (2022) · Cytotherapy · doi:10.1016/j.jcyt.2022.08.008 · Cited by 25
Highly Sensitive Aptasensor for Detecting Cancerous Exosomes Based on Clover-like Gold Nanoclusters
Cheng, W., Duan, C., Chen, Y., Li, D., Hou, Z., Yao, Y., Jiao, J., & Xiang, Y. (2022) · Analytical Chemistry · doi:10.1021/acs.analchem.2c04280 · Cited by 25
Management of Sjogren’s Dry Eye Disease—Advances in Ocular Drug Delivery Offering a New Hope
Wu, K. Y., Chen, W. T., Chu-Bédard, Y.-K., Patel, G., & Tran, S. D. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics15010147 · Cited by 25
Cha, B. S., Jang, Y. J., Lee, E. S., Kim, D. Y., Woo, J. S., Son, J., Kim, S., Shin, J., Han, J., Kim, S. H., et al. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202300854 · Cited by 25
Kang, C., Ren, X., Lee, D., Ramesh, R., Nimmo, S., Yang‐Hartwich, Y., & Kim, D. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.11.031 · Cited by 25
Tang, P., Song, F., Chen, Y., Gao, C., Ran, X., Li, Y., Chen, Z., Zhang, Z., Wei, W., Peng, Z., et al. (2024) · Applied Materials Today · doi:10.1016/j.apmt.2024.102084 · Cited by 25
Iurca, I., Tirpe, A., Zimța, A., Moldovan, C. S., Gulei, D., Slabý, O., Condorelli, G., & Berindan‐Neagoe, I. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00870 · Cited by 25
Oey, O., Ghaffari, M., Li, J. J., & Hosseini‐Beheshti, E. (2021) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2021.103495 · Cited by 25
Ansermino, C., Pavlović, R., Braccia, C., Drago, D., Anelli, C., & Andolfo, A. (2026) · Biomarker Research · doi:10.1186/s40364-025-00889-6 · Cited by 24
Chigozie, V. U. (2026) · Clinical and Experimental Medicine · doi:10.1007/s10238-026-02092-9 · Cited by 24
A CMOS-Based Capacitive Biosensor for Detection of a Breast Cancer MicroRNA Biomarker
Kuo, Y.-H., Chen, Y.-S., Huang, P.-C., & Lee, G. (2020) · IEEE Open Journal of Nanotechnology · doi:10.1109/ojnano.2020.3035349 · Cited by 24
Recent advances in biosensors for detection of exosomes
Zhu, X., Chen, H., Zhou, Y., Wu, J., Ramakrishna, S., Peng, X., Nanda, H. S., & Zhou, Y. (2021) · Current Opinion in Biomedical Engineering · doi:10.1016/j.cobme.2021.100280 · Cited by 24
The Potential of Exosomes in Allergy Immunotherapy
Engeroff, P., & Vogel, M. (2022) · Vaccines · doi:10.3390/vaccines10010133 · Cited by 24
Rajabi, H., Konyalılar, N., Erkan, S., Mortazavi, D., Korkunc, S. K., Kayalar, Ö., Bayram, H., & Rahbarghazi, R. (2022) · Stem Cell Research & Therapy · doi:10.1186/s13287-022-02820-4 · Cited by 24
Cheng, J., Wang, X., Yuan, X., Liu, G., & Chu, Q. (2022) · PubMed Central · Cited by 24
Exosome-mediated aptamer S58 reduces fibrosis in a rat glaucoma filtration surgery model
Lin, Q., Leng, Y., Zhu, X., Tang, M., Lin, Y., Luo, W., Jiang, B., Chen, X., & Xie, L. (2022) · International Journal of Ophthalmology · doi:10.18240/ijo.2022.05.02 · Cited by 25
MicroRNAs in the cancer cell-to-cell communication: An insight into biological vehicles
Mansoori, B., Baradaran, B., Nazari, A., Gaballu, F. A., Cho, W. C. S., & Mansoori, B. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113449 · Cited by 24
Jahanbani, Y., Beiranvand, T., Mamaghani, P. Y., Maleki, L. A., & Yousefi, M. (2023) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2023.103833 · Cited by 24
Novel Technologies for Exosome and Exosome-like Nanovesicle Procurement and Enhancement
Martínez-Santillán, A., & González‐Valdez, J. (2023) · Biomedicines · doi:10.3390/biomedicines11051487 · Cited by 24
Clinical Theranostics Trademark of Exosome in Glioblastoma Metastasis
Nag, S., Bhattacharya, B., Dutta, S., Mandal, D., Mukherjee, S., Anand, K., Eswaramoorthy, R., Thorat, N. D., Jha, S. K., & Gorai, S. (2023) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.3c00212 · Cited by 24
Liquid biopsy for gastric cancer: Techniques, applications, and future directions
del Arco, C. D., Fernández‐Aceñero, M. J., & Medina, L. O. (2024) · World Journal of Gastroenterology · doi:10.3748/wjg.v30.i12.1680 · Cited by 24
Mesenchymal stem cell-derived exosomes: a novel therapeutic frontier in hematological disorders
Saadh, M. J., Hussein, A., Bayani, A., Dastafkan, S., Amiri, M., Akbari, A., Shahsavan, S., Samarkhazan, H. S., & Asl, V. S. (2025) · Medical Oncology · doi:10.1007/s12032-025-02742-0 · Cited by 24
Progress on diagnosis and treatment of central nervous system tuberculosis
Chen, W., Huang, L., Tang, Q., Wang, S., Hu, C., & Zhang, X. (2020) · Radiology of Infectious Diseases · doi:10.1016/j.jrid.2020.07.005 · Cited by 24
López-Pérez, Ó., Sánz-Rubio, D., Hernaiz, A., Betancor, M., Otero, A., Castilla, J., Andréoletti, O., Badiola, J. J., Zaragoza, P., Bolea, R., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22136822 · Cited by 24
Advances with Long Non-Coding RNAs in Alzheimer’s Disease as Peripheral Biomarker
Garofalo, M., Pandini, C., Sproviero, D., Pansarasa, O., Cereda, C., & Gagliardi, S. (2021) · Genes · doi:10.3390/genes12081124 · Cited by 24
Exosomal circRNAs: new players in colorectal cancer
Vakhshiteh, F., Hassani, S., Momenifar, N., & Pakdaman, F. (2021) · Cancer Cell International · doi:10.1186/s12935-021-02112-6 · Cited by 24
Zelli, V., Compagnoni, C., Capelli, R., Corrente, A., Nolfi, M. D. V., Zazzeroni, F., Alesse, E., & Tessitore, A. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.940056 · Cited by 24
Application of Milk Exosomes for Musculoskeletal Health: Talking Points in Recent Outcomes
Kim, N.-H., Kim, J., Lee, J.-Y., Bae, H.-A., & Kim, C. Y. (2023) · Nutrients · doi:10.3390/nu15214645 · Cited by 23
Sun, Y., Li, B., Song, B., Xia, Y., Zhou, X., Lin, F., Rao, T., & Fan, C. (2025) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-03246-9 · Cited by 23
Xia, X., Zhu, J., Xu, X., Wang, W., Zhao, R., Wu, K., Huang, H., Qian, Y., Luo, Z., Xu, F., et al. (2025) · Annals of Medicine · doi:10.1080/07853890.2025.2549524 · Cited by 23
Defining lung cancer stem cells exosomal payload of miRNAs in clinical perspective
Aramini, B., Masciale, V., & Haider, K. H. (2020) · World Journal of Stem Cells · doi:10.4252/wjsc.v12.i6.406 · Cited by 23
Proteomics in thyroid cancer and other thyroid-related diseases: A review of the literature
Uçal, Y., & Özpınar, A. (2020) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2020.140510 · Cited by 23
Effects of Chronic Kidney Disease and Uremic Toxins on Extracellular Vesicle Biology
Yaker, L., Kamel, S., Ausseil, J., & Boullier, A. (2020) · Toxins · doi:10.3390/toxins12120811 · Cited by 23
Amundson, D. E., Shah, U. S., de Necochea-Campion, R., Jacobs, M. E., LaRosa, S. P., & Fisher, C. J. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.744141 · Cited by 23
Bai, L., Gao, Z., Jiang, A., Ren, S., & Wang, B. (2021) · Anti-Cancer Drugs · doi:10.1097/cad.0000000000001221 · Cited by 23
Crescentic Glomerulonephritis: Pathogenesis and Therapeutic Potential of Human Amniotic Stem Cells
Mushafi, A. A., Ooi, J. D., & Odobasic, D. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.724186 · Cited by 23
Exosomes as Intercellular Messengers in Hypertension
Arishe, O. O., Priviero, F. B. M., Wilczynski, S., & Webb, R. C. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222111685 · Cited by 23
Extracellular Vesicles as Mediators of Therapy Resistance in the Breast Cancer Microenvironment
Samuels, M., Cilibrasi, C., Papanastasopoulos, P., & Giamas, G. (2022) · Biomolecules · doi:10.3390/biom12010132 · Cited by 23
Improving Isolation of Extracellular Vesicles by Utilizing Nanomaterials
Zhang, H., Zhang, Q., Deng, Y., Chen, M., & Yang, C. (2021) · Membranes · doi:10.3390/membranes12010055 · Cited by 23
Praja, R. K., Wongwattanakul, M., Tippayawat, P., Phoksawat, W., Jumnainsong, A., Sornkayasit, K., & Leelayuwat, C. (2022) · Cells · doi:10.3390/cells11030458 · Cited by 23
Mecocci, S., Paolis, L. D., Zoccola, R., Fruscione, F., Ciucis, C. G. D., Chiaradia, E., Moccia, V., Tognoloni, A., Pascucci, L., Zoppi, S., et al. (2022) · Biomedicines · doi:10.3390/biomedicines10123264 · Cited by 23
Exosome Mediated Cancer Therapeutic Approach:Present Status and Future Prospectives
Roy, A., Girija, A. S. S., Ganesh, P. S., Saravanan, M., & Sunny, B. C. (2023) · Asian Pacific Journal of Cancer Prevention · doi:10.31557/apjcp.2023.24.2.363 · Cited by 23
Glioblastoma-Derived Small Extracellular Vesicles: Nanoparticles for Glioma Treatment
Araujo‐Abad, S., Manresa-Manresa, A., Rodríguez-Cañas, E., Fuentes-Baile, M., García-Morales, P., Mallavia, R. M., Saceda, M., & Romero, C. D. J. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24065910 · Cited by 23
Astrocyte-Derived Exosomes Differentially Shape T Cells’ Immune Response in MS Patients
Szpakowski, P., Ksiazek-Winiarek, D. J., Czpakowska, J., Kałuża, M., Milewska-Jędrzejczak, M., & Glabinski, A. R. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24087470 · Cited by 23
Gečys, D., Skredėnienė, R., Gečytė, E., Kazlauskas, A., Balnytė, I., & Jekabsone, A. (2023) · Cells · doi:10.3390/cells12091247 · Cited by 23
Valiukevičius, P., Mačiulaitis, J., Pangonytė, D., Siratavičiūtė, V., Kluszczyńska, K., Kuzaitytė, U., Insodaitė, R., Čiapienė, I., Grigalevičiūtė, R., Zigmantaitė, V., et al. (2023) · Cells · doi:10.3390/cells12232729 · Cited by 23
Ebeyer-Masotta, M., Eichhorn, T., Fischer, M. B., & Weber, V. (2024) · Transfusion and Apheresis Science · doi:10.1016/j.transci.2024.103891 · Cited by 23
Advances in the Study of Extracellular Vesicles for Bone Regeneration
Yao, J., Liu, Y., Du, J., Xu, J., Luo, Z., Liu, Y. F., & Guo, L. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25063480 · Cited by 24
Self-citationExploring Epigenetic and Genetic Modulation in Animal Responses to Thermal Stress
Wang, J., Raza, S. H. A., Pant, S. D., Juan, Z., Prakash, A., Abdelnour, S. A., Aloufi, B. H., Mahasneh, Z. M. H., Amin, A. A., Shokrollahi, B., et al. (2024) · Molecular Biotechnology · doi:10.1007/s12033-024-01126-5 · Cited by 23
Chen, Y., Lu, C.-H., Ke, C., & Liu, R.-S. (2021) · Membranes · doi:10.3390/membranes11100796 · Cited by 23
Tsai, Y., Hung, W., Chang, W., Wu, P., Wu, L., Lee, S., Kuo, M., & Hsu, Y. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.789716 · Cited by 23
Extracellular vesicles in cancer pros and cons: The importance of the evidence-based medicine
Cappello, F., & Fais, S. (2022) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2022.01.011 · Cited by 23
Storage Stability of Blood Samples for miRNAs in Glycosylated Extracellular Vesicles
Ma, C., Ding, R., Hao, K., Du, W., Xu, L., Gao, Q., & Yu, C. (2023) · Molecules · doi:10.3390/molecules29010103 · Cited by 22
Bok, E., Seo, S. Y., Lee, H. G., Wimalasena, S. H. M. P., Kim, E., Cho, A., Jung, Y., Hur, T., So, K.-M., Lee, S., et al. (2024) · Journal of Animal Science and Technology · doi:10.5187/jast.2024.e45 · Cited by 22
Hariharan, H. P., Kesavan, Y., & Sella, R. N. (2021) · Molecular Biology Reports · doi:10.1007/s11033-021-06733-y · Cited by 22
Diagnostic Potential of Plasma Extracellular Vesicle miR-483-3p and Let-7d-3p for Sepsis
Qiu, G., Fan, J., Zheng, G., He, J., Lin, F., Ge, M., Huang, L.-F., Wang, J., Xia, J. L., Huang, R., et al. (2022) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2022.814240 · Cited by 22
Non-Exosomal and Exosome-Derived miRNAs as Promising Biomarkers in Canine Mammary Cancer
Petroušková, P., Hudáková, N., Maloveská, M., Humeník, F., & Cizkova, D. (2022) · Life · doi:10.3390/life12040524 · Cited by 22
Quality control mechanisms that protect nuclear envelope identity and function
Mannino, P. J., & Lusk, C. P. (2022) · The Journal of Cell Biology · doi:10.1083/jcb.202205123 · Cited by 22
Leveraging the CSF proteome toward minimally-invasive diagnostics surveillance of brain malignancies
Mikolajewicz, N., Khan, S., Trifoi, M. D., Skakdoub, A., Ignatchenko, V., Mansouri, S., Zuccato, J., Zacharia, B. E., Glantz, M., Zadeh, G. M., et al. (2022) · Neuro-Oncology Advances · doi:10.1093/noajnl/vdac161 · Cited by 22
Complex RNA world in small extracellular vesicles for liquid biopsy in cancer management
Wang, S., Lin, Y., Zhang, Y., Qiu, X., Pan, Y., Yeung, S. J., & Zhang, H. (2022) · Extracellular Vesicle · doi:10.1016/j.vesic.2022.100015 · Cited by 22
Self-citationHuang, H., Liu, S., Zhao, X., Zhao, P., Jia, Q., Ma, H., & Lin, Q. (2023) · Eye · doi:10.1038/s41433-023-02473-4 · Cited by 22
MASTRONIKOLIS, N. S., Kyrodimos, E., Spyropoulou, D., Delides, A., Giotakis, E. I., Piperigkou, Z., & Karamanos, N. K. (2023) · Cancers · doi:10.3390/cancers15072156 · Cited by 22
Recent Advancements on the Use of Exosomes as Drug Carriers for the Treatment of Glioblastoma
Galardi, A., Bethlen, A. D., Paolo, V. D., Lampis, S., Mastronuzzi, A., & Giannatale, A. D. (2023) · Life · doi:10.3390/life13040964 · Cited by 22
Role of Gasdermin E in the Biogenesis of Apoptotic Cell–Derived Exosomes
Hur, J., Kim, Y. J., Choi, D. A., Kang, D. W., Kim, J., Yoo, H. S., Shahriyar, S. A., Mustajab, T., Kim, J., Han, K. R., et al. (2023) · The Journal of Immunology · doi:10.4049/jimmunol.2200342 · Cited by 22
Soleymani, T., Chen, T.-Y., Gonzalez‐Kozlova, E., & Dogra, N. (2023) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2023.1156821 · Cited by 22
Habib, A., Liang, Y., & Zhu, N. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1249133 · Cited by 22
gougheri, K. A., Ahmadi, A., Ahmadabadi, M. G., Babajani, A., Yazdanpanah, G., Bahrami, S., Hassani, M., & Niknejad, H. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115801 · Cited by 22
Zhang, Y., & Xie, J. (2024) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1344060 · Cited by 22
Self-citationHu, Y., Yang, R., Liu, S., Song, Z., & Wang, H. (2024) · Drug Design Development and Therapy · doi:10.2147/dddt.s448807 · Cited by 22
Wang, L., Wang, J., Ao, X., Wei, L., Pei, M., Shen, T., Xian, X., Yang, K., Fei, L., Pan, Y., et al. (2024) · Journal of Nanobiotechnology · doi:10.1186/s12951-024-02633-y · Cited by 22
Exosome Mediated Cell-Cell Crosstalk in Tissue Injury and Repair
Yadav, A., Nandy, A., Sharma, A., & Ghatak, S. (2024) · Results and problems in cell differentiation · doi:10.1007/978-3-031-62036-2_12 · Cited by 22
Biogenesis, Biologic Function and Clinical Potential of Exosomes in Different Diseases
Beshbishy, A. M., Alghamdi, S. A., Onyiche, T. E., Zahoor, M., Rivero-Pérez, N., Zaragoza-Bastida, A., Ghorab, M. A., Meshaal, A. K., El-Esawi, M. A., Hetta, . F., et al. (2020) · Applied Sciences · doi:10.3390/app10134428 · Cited by 22
Extracellular Vesicle Associated Non-Coding RNAs in Lung Infections and Injury
Kwok, Z. H., Ni, K., & Jin, Y. (2021) · Cells · doi:10.3390/cells10050965 · Cited by 22
Wen, J., Moloney, E. B., Canning, A., Donohoe, E., Ritter, T., Wang, J., Xiang, D., Wu, J., & Li, Y. (2021) · Pharmacological Research · doi:10.1016/j.phrs.2021.105833 · Cited by 22
Non‐coding RNAs in malaria infection
Lodde, V., Floris, M., Muroni, M. R., Cucca, F., & Idda, M. L. (2021) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1697 · Cited by 22
Kadhim, M. A., Cagatay, S. T., & Elbakrawy, E. M. (2021) · International Journal of Radiation Biology · doi:10.1080/09553002.2021.1980630 · Cited by 22
Le, T. B. C., Burassakarn, A., Tongchai, P., Ekalaksananan, T., Aromseree, S., Phanthanawiboon, S., Polsan, Y., Alexander, N. D. E., Overgaard, H. J., & Pientong, C. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232012117 · Cited by 22
Guo, D., Yan, J., Yang, Z., Chen, M., Zhong, W., Yuan, X., & Yu, S. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1476865 · Cited by 21
GP73-dependent regulation of exosome biogenesis promotes colorectal cancer liver metastasis
Huang, L., Meng, W., Li, H., Yu, M., Wan, L., Zhao, R., Gao, Q., Sun, L., Hou, X., Mo, Y., et al. (2025) · Molecular Cancer · doi:10.1186/s12943-025-02350-6 · Cited by 21
An Acoustofluidic Device for Sample Preparation and Detection of Small Extracellular Vesicles
Liu, J. F., Xia, J., Rich, J. T., Zhao, S., Yang, K., Lu, B., Chen, Y., Ye, T., & Huang, T. J. (2025) · Cyborg and Bionic Systems · doi:10.34133/cbsystems.0319 · Cited by 21
Metadata
- Authors
- Zhang, Y., Liu, Y., Liu, H., & Tang, W. H.
- Affiliations
- Guangzhou Women and Children Medical Center (CN)
- Corresponding author
- Liu, Haiying
- Tang, Wai Ho
- Venue
- Cell & Bioscience
- Published
- 2019-02-15
- Volume
- 9
- Issue
- 1
- Pages
- 19-19
- ISSN
- 2045-3701 (ISSN-L)
- PMC
- PMC6377728
- OpenAlex
- W2931418311
- Cited by
- 2,119
- References
- 156
- Citations by year
- 2026: 203 · 2025: 327 · 2024: 386 · 2023: 361 · 2022: 334 · 2021: 297 · 2020: 184 · 2019: 24
- FWCI
- 18.57
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Cell & Bioscience (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, other-oa)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Extracellular vesicles in disease
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular transport and secretion
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Keywords
- exosomes, exosome biogenesis, multivesicular bodies, exosome cargo, exosome uptake, cell targeting, diagnostic biomarkers, prognostic factors, drug delivery, gene delivery, extracellular vesicles
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
