Antenatal care and mothers’ education improved iron-folic acid adherence at Denbiya district health centers, Northwest Ethiopia: using pills count method
Open accessAbstract
BACKGROUND: Anemia is the leading public health problem among pregnant women worldwide. Iron-Folic Acid (IFA) supplementation is the strategy to control pregnancy induced anemia, but its adherence status was not well studied. OBJECTIVE: The aim of this study was to assess the prevalence of IFA adherence and associated factors among pregnant women attending antenatal care at Denbiya district health centers. METHODS: Cross -sectional study design was conducted in Denbiya district health centers from April 2 to May 27, 2016. A total of 395 study participants were enrolled in the study. Systematic random sampling was used to select study participants. Data were collected using the interviewer-administered technique. Adherence to IFA supplementation was assessed by the pills count method. A logistic regression model was used. RESULTS: The study revealed that the prevalence of good adherence towards IFA supplementation among Antenatal care (ANC) service users' at Denbiya district health centers were found to be 28.01% [95% CI, 24.01, 35.9]. Attending secondary school and above [Adjusted Odds Ratio (AOR) = 3.44, 95% CI: 1.09, 10.92], having two ANC visits [AOR = 2.53, 95% CI: 1.34, 4.76] and three and above ANC visits [AOR = 4.14, 95% CI: 2.14, 8.01] were significantly associated with good adherence of IFA supplementation. To the contrary, husband education status; secondary school and above reduced the odds of good adherence by 77% compared to illiterates to IFA supplementation [AOR = 0.23, 95% CI: 0.07, 0.72]. CONCLUSION: The prevalence of good adherence among pregnant women towards IFA supplementation was low. Mothers' education and having two or more ANC visits were positively associated with good adherence towards IFA supplementation.
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The finding that husbands with secondary education or above played a positive role is consistent with studies conducted in Ethiopia.
“Husbands who completed secondary education or above played a positive role in promoting adherence to IFAS among their wives, which is consistent with studies conducted in Ethiopia [30].”
From Magnitude and determinants of adherence to iron-folic acid supplementation among Somaliland pregnant women in Ahmed-dhagah district: A facility based cross-sectional study (2024) · cites this paper as [30]
The Discussion reports the opposite association: husbands’ secondary education or above was associated with 77% lower odds of good IFA adherence than husbands’ illiteracy (AOR 0.23, 95% CI 0.07–0.72). Table 3 in the Results reports the same adjusted association. The positive education finding concerns mothers, not husbands. (LLM, conf=0.94)
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Cites
Daily oral iron supplementation during pregnancy
Peña-Rosas, J. P., De-Regil, L. M., Garcia-Casal, M. N., & Dowswell, T. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004736.pub5 · Cited by 565 · cited 1× · see citing works
“Conducting research on IFA adherence for pregnant women provides a double benefit for the mother and the fetus [15].”
BackgroundCompliance with iron-folic acid (IFA) therapy among pregnant women in an urban area of south India
Mithra, P., Unnikrishnan, B., Rekha, T., Nithin, K., Mohan, K., Kulkarni, V, Kulkarni, V, & Agarwal, D. (2014) · African Health Sciences · doi:10.4314/ahs.v13i4.3 · Cited by 181 · see citing works
Gebremedhin, S., Samuel, A., Mamo, G., Moges, T., & Assefa, T. (2014) · BMC Public Health · doi:10.1186/1471-2458-14-607 · Cited by 156 · see citing works
Taye, B., Abeje, G., & Mekonen, A. (2015) · Pan African Medical Journal · doi:10.11604/pamj.2015.20.43.4894 · Cited by 155 · see citing works
Determinants of compliance with iron supplementation among pregnant women in Senegal
Seck, B. C., & Jackson, R. T. (2008) · Public Health Nutrition · doi:10.1017/s1368980007000924 · Cited by 154 · see citing works
Getachew, M., Abay, M., Zelalem, H., Gebremedhin, T., Grum, T., & Bayray, A. (2018) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-018-1716-2 · Cited by 84 · see citing works
Gebreamlak, B., Dadi, A. F., & Atnafu, A. (2017) · PLOS ONE · doi:10.1371/journal.pone.0169415 · Cited by 80 · see citing works
Flagged first, then by citations
Research works printed but not linked: 16
- [1]McLean E Cogswell M Egli I Wojdyla D De Benoist B Worldwide prevalence of anaemia, WHO vitamin and mineral nutrition information system, 1993–2005 Public Health Nutr 2009 12 4 444 454 10.1017/S1368980008002401 18498676 · DOI · Paper page
- [3]Goddard AF James MW McIntyre AS Scott BB Guidelines for the management of iron deficiency anaemia Gut. 2011 60 10 1309 1316 10.1136/gut.2010.228874 21561874 · DOI
- [4]Osungbade Kayode O. Oladunjoye Adeolu O. Preventive Treatments of Iron Deficiency Anaemia in Pregnancy: A Review of Their Effectiveness and Implications for Health System Strengthening Journal of Pregnancy 2012 2012 1 7 10.1155/2012/454601 PMC3400371 22848829 · DOI
- [5]WHO. Daily iron and folic acid supplementation in pregnant women. Geneva: World Health Organization guideline; 2012. 23586119
- [6]Lutsey PL Dawe D Villate E Valencia S Lopez O Iron supplementation compliance among pregnant women in Bicol, Philippines Public Health Nutr 2008 11 1 76 82 10.1017/S1368980007000237 17519048 · DOI · Paper page
- [7]AId S Batista Filho M Bresani CC Ferreira LOC Figueiroa JN Adherence and side effects of three ferrous sulfate treatment regimens on anemic pregnant women in clinical trials Cad Saude Publica 2009 25 6 1225 1233 10.1590/S0102-311X2009000600005 19503953 · DOI
- [11]Nwaru BI Salomé G Abacassamo F Augusto O Cliff J Sousa C Adherence in a pragmatic randomized controlled trial on prophylactic iron supplementation during pregnancy in Maputo, Mozambique Public Health Nutr 2015 18 6 1127 1134 10.1017/S1368980014001359 24999785 PMC10271523 · DOI · Paper page
- [12]Gebre Abel Assessment of Factors Associated with Adherence to Iron-Folic Acid Supplementation Among Urban and Rural Pregnant Women in North Western Zone of Tigray, Ethiopia: Comparative Study International Journal of Nutrition and Food Sciences 2015 4 2 161 10.11648/j.ijnfs.20150402.16 · DOI · Paper page
- [14]Tolkien Z Stecher L Mander AP Pereira DI Powell JJ Ferrous sulfate supplementation causes significant gastrointestinal side-effects in adults: a systematic review and meta-analysis PLoS One 2015 10 2 e0117383 10.1371/journal.pone.0117383 25700159 PMC4336293 · DOI · Paper page
- [19]Ugwu E Olibe A Obi S Ugwu A Determinants of compliance to iron supplementation among pregnant women in Enugu, southeastern Nigeria Niger J Clin Pract 2014 17 5 608 612 10.4103/1119-3077.141427 25244272 · DOI · Paper page
- [21]Ratanasiri T Koju R Effect of knowledge and perception on adherence to iron and folate supplementation during pregnancy in Kathmandu, Nepal J Med Assoc Thail 2014 97 10 S67 S74 25816540
- [23]Sina Siabani MMA, Maryam Babakhani, Fateme Rezaei, and Soraya Siabani. Determinants of adherence to Iron and folate supplementation among pregnant women in West Iran: a population based cross-sectional study. Qual Prim Care 2017;25(3):157–163. PMC6581656 31239847
- [24]Pal PP Sharma S Sarkar TK Mitra P Iron and folic acid consumption by the ante-natal mothers in a rural area of India in 2010 Int J Prev Med 2013 4 10 1213 24319564 PMC3843311
- [25]Raut BK Jha MK Shrestha A Sah A Sapkota A Byanju S Prevalence of iron deficiency anemia among pregnant women before iron supplementation in Kathmandu university hospital/Dhulikhel hospital J Gynecol Obstet 2014 2 4 54 58 10.11648/j.jgo.20140204.12 · DOI
- [26]Agrawal S Fledderjohann J Vellakkal S Stuckler D Adequately diversified dietary intake and iron and folic acid supplementation during pregnancy is associated with reduced occurrence of symptoms suggestive of pre-eclampsia or eclampsia in Indian women PLoS One 2015 10 3 e0119120 10.1371/journal.pone.0119120 25785774 PMC4364955 · DOI
- [28]Birhanu TM Birarra MK Mekonnen FA Compliance to iron and folic acid supplementation in pregnancy, Northwest Ethiopia BMC Res Notes 2018 11 1 345 10.1186/s13104-018-3433-3 29848380 PMC5977755 · DOI
Cited by
Sorted by citations
Sendeku, F. W., Azeze, G. G., & Fenta, S. L. (2020) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-020-2835-0 · Cited by 108 · see citing works
Fite, M. B., Roba, K. T., Oljira, L., Tura, A. K., & Yadeta, T. A. (2021) · PLOS ONE · doi:10.1371/journal.pone.0249789 · Cited by 69 · see citing works
Mohamed, A. I., Mohamed, J., Abdillahi, M. M., Abdeeq, B. A., & Lema, T. B. (2024) · Clinical Epidemiology and Global Health · doi:10.1016/j.cegh.2024.101565 · Cited by 11 · see citing works
- Authors
- Tarekegn, M., Wubshet, M., Atenafu, A., Derso, T., & Woretaw, A.
- Affiliations
- Addis Ababa University (ET)
- University of Gondar (ET)
- Corresponding author
- Tarekegn, Missa
- Venue
- Archives of Public Health
- Published
- 2019-06-25
- Volume
- 77
- Issue
- 1
- Pages
- 30-30
- ISSN
- 0778-7367 (ISSN-L)
- 2049-3258
- PMC
- PMC6591834
- OpenAlex
- W2949502025
- Cited by
- 24
- References
- 7
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 1 · 2023: 5 · 2022: 3 · 2021: 5 · 2020: 4 · 2019: 1
- FWCI
- 3.38
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Archives of Public Health (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- University of Gondar
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Global Maternal and Child Health
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Public Health and Nutrition
- Health Sciences › Health Professions › General Health Professions › Maternal and Neonatal Healthcare
- Keywords
- iron and folic acid supplementation, medication adherence, prenatal care, pregnant women, maternal education, pill count method, anemia in pregnancy, number of antenatal visits, husband education
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