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Deprescribing benzodiazepines and Z-drugs in community-dwelling adults: a scoping review
Open accessAbstract
BACKGROUND: Long-term sedative use is prevalent and associated with significant morbidity, including adverse events such as falls, cognitive impairment, and sedation. The development of dependence can pose significant challenges when discontinuation is attempted as withdrawal symptoms often develop. We conducted a scoping review to map and characterize the literature and determine opportunities for future research regarding deprescribing strategies for long-term benzodiazepine and Z-drug (zopiclone, zolpidem, and zaleplon) use in community-dwelling adults. METHODS: We searched PubMed, Cochrane Central Register of Controlled Trials, EMBASE, PsycINFO, CINAHL, TRIP, and JBI Ovid databases and conducted a grey literature search. Articles discussing methods for deprescribing benzodiazepines or Z-drugs in community-dwelling adults were selected. RESULTS: Following removal of duplicates, 2797 articles were reviewed for eligibility. Of these, 367 were retrieved for full-text assessment and 139 were subsequently included for review. Seventy-four (53%) articles were original research, predominantly randomized controlled trials (n = 52 [37%]), whereas 58 (42%) were narrative reviews and seven (5%) were guidelines. Amongst original studies, pharmacologic strategies were the most commonly studied intervention (n = 42 [57%]). Additional deprescribing strategies included psychological therapies (n = 10 [14%]), mixed interventions (n = 12 [16%]), and others (n = 10 [14%]). Behaviour change interventions were commonly combined and included enablement (n = 56 [76%]), education (n = 36 [47%]), and training (n = 29 [39%]). Gradual dose reduction was frequently a component of studies, reviews, and guidelines, but methods varied widely. CONCLUSIONS: Approaches proposed for deprescribing benzodiazepines and Z-drugs are numerous and heterogeneous. Current research in this area using methods such as randomized trials and meta-analyses may too narrowly encompass potential strategies available to target this phenomenon. Realist synthesis methods would be well suited to understand the mechanisms by which deprescribing interventions work and why they fail.
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“however, dependence, and withdrawal still commonly occur (Nice, 2004; Pollmann et al., 2015) even after brief or intermittent use (Kales et al., 1991).”
From Pharmacological principles for safe benzodiazepine and Z-drug dose reduction (2026) · cites this paper as Pollmann et al., 2015
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Guidelines universally recommend tapering benzodiazepines, yet there is no definitive method, and most advice is based on expert consensus rather than empirical evidence or pharmacological principles, resulting in conflicting advice (Brunner et al., 2025; Pollmann, Murphy, Bergman, & Gardner, 2015).”
From Pharmacological principles for safe benzodiazepine and Z-drug dose reduction (2026) · cites this paper as Pollmann, Murphy, Bergman, & Gardner, 2015
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Guidelines universally recommend tapering benzodiazepines, yet there is no definitive method, and most advice is based on expert consensus rather than empirical evidence or pharmacological principles, resulting in conflicting advice (Brunner et al., 2025; Pollmann, Murphy, Bergman, & Gardner, 2015).”
From Pharmacological principles for safe benzodiazepine and Z-drug dose reduction (2026) · cites this paper as Pollmann, Murphy, Bergman, & Gardner, 2015
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“In two scoping reviews of benzodiazepine tapering studies (Brandt et al., 2024; Pollmann et al., 2015), most original investigations and guidelines employed reductions of 10%–25% every 1–2 weeks in linear fashion (i.e. 75% of the original daily dose, then 50% of the original dose, 25% of the original dose), and then discontinuation (Pollmann et al., 2015).”
From Pharmacological principles for safe benzodiazepine and Z-drug dose reduction (2026) · cites this paper as Pollmann et al., 2015
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“The use of pharmacological strategies involving the addition of a second agent is among the most commonly-employed approaches in the process of Z-drug deprescription.”
From Z-drug abuse and dependence: Clinical guideline of the Brazilian Academy of Neurology for diagnosis and management (2025) · cites this paper as [81]
Experimental — accuracy not yet measured
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In the citing paper
“Despite this growing concern, there is a scarcity of clinical trials and studies exploring therapeutic strategies to manage zolpidem dependence in adults and older populations. 81”
From Z-drug abuse and dependence: Clinical guideline of the Brazilian Academy of Neurology for diagnosis and management (2025) · cites this paper as [81]
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In the citing paper
“Guidelines universally recommend tapering benzodiazepines, yet there is no definitive method, and most advice is based on expert consensus rather than empirical evidence or pharmacological principles, resulting in conflicting advice (Brunner et al., 2025; Pollmann, Murphy, Bergman, & Gardner, 2015).”
From Pharmacological principles for safe benzodiazepine and Z-drug dose reduction (2026) · cites this paper as Pollmann, Murphy, Bergman, & Gardner, 2015
The cited source says what the claim attributes to it.
In the citing paper
“Guidelines universally recommend tapering benzodiazepines, yet there is no definitive method, and most advice is based on expert consensus rather than empirical evidence or pharmacological principles, resulting in conflicting advice (Brunner et al., 2025; Pollmann, Murphy, Bergman, & Gardner, 2015).”
From Pharmacological principles for safe benzodiazepine and Z-drug dose reduction (2026) · cites this paper as Pollmann, Murphy, Bergman, & Gardner, 2015
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“The final dose before complete cessation was generally 25% or 50% of the original dose, when reported, in these studies (Pollmann et al., 2015), with some implying a final dose of 5%–10% of the original dose (Brandt et al., 2024).”
From Pharmacological principles for safe benzodiazepine and Z-drug dose reduction (2026) · cites this paper as Pollmann et al., 2015
In the citing paper
“This is likely explained by the limited number of randomised controlled trials and lower quality heterogenous evidence variably supporting their use, as reviewed in further detail elsewhere.163,169,170”
In the citing paper
“The focus of BZD deprescribing, especially among older adults, has become more prominent in Western and European nations especially in recent years given an aging demographic trend and the known risks of these agents in this population.163,164”
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Citations
Cites
Scoping studies: towards a methodological framework
Arksey, H., & O'Malley, L. (2005) · International Journal of Social Research Methodology · doi:10.1080/1364557032000119616 · Cited by 36,742
Scoping studies: advancing the methodology
Levac, D., Colquhoun, H., & O'Brien, K. K. (2010) · Implementation Science · doi:10.1186/1748-5908-5-69 · Cited by 15,268
Damschroder, L. J., Aron, D. C., Keith, R. E., Kirsh, S. R., Alexander, J. A., & Lowery, J. C. (2009) · Implementation Science · doi:10.1186/1748-5908-4-50 · Cited by 14,496
Michie, S., van Stralen, M. M., & West, R. (2011) · Implementation Science · doi:10.1186/1748-5908-6-42 · Cited by 13,697
Hoffmann, T. C., Glasziou, P. P., Boutron, I., Milne, R., Perera, R., Moher, D., Altman, D. G., Barbour, V., Macdonald, H., Johnston, M., et al. (2014) · BMJ · doi:10.1136/bmj.g1687 · Cited by 10,548
Grading quality of evidence and strength of recommendations
(2004) · BMJ · doi:10.1136/bmj.328.7454.1490 · Cited by 8,477
Realist review - a new method of systematic review designed for complex policy interventions
Pawson, R., Greenhalgh, T., Harvey, G., & Walshe, K. (2005) · Journal of Health Services Research & Policy · doi:10.1258/1355819054308530 · Cited by 3,190
Users' Guides to the Medical Literature
Guyatt, G. H. (1993) · JAMA · doi:10.1001/jama.270.17.2096 · Cited by 3,083
The well-built clinical question: A key to evidence-based decisions
(1995) · ACP Journal Club · doi:10.7326/acpjc-1995-123-3-a12 · Cited by 2,931
The Agency for Healthcare Research and Quality
Baine, W. B. (2006) · Italian Journal of Public Health · doi:10.2427/5924 · Cited by 1,191
Sedative hypnotics in older people with insomnia: meta-analysis of risks and benefits
Glass, J., Lanctôt, K. L., Herrmann, N., Sproule, B. A., & Busto, U. E. (2005) · BMJ · doi:10.1136/bmj.38623.768588.47 · Cited by 1,161
Users' Guides to the Medical Literature: IX. A Method for Grading Health Care Recommendations
Guyatt, G. H. (1995) · JAMA · doi:10.1001/jama.1995.03530220066035 · Cited by 846
Guyatt, G., Haynes, R., Jaeschke, R., Cook, D. J., Green, L. A., Naylor, C., Wilson, M., & Richardson, W. S. (2000) · Journal of the American Medical Association (JAMA) · doi:10.1001/jama.284.10.1290 · Cited by 788
Benzodiazepine Use in the United States
Olfson, M., King, M., & Schoenbaum, M. (2015) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2014.1763 · Cited by 786
Realist synthesis: illustrating the method for implementation research
Rycroft-Malone, J., McCormack, B., Hutchinson, A. M., DeCorby, K., Bucknall, T. K., Kent, B., Schultz, A., Snelgrove-Clarke, E., Stetler, C. B., Titler, M., et al. (2012) · Implementation Science · doi:10.1186/1748-5908-7-33 · Cited by 742
Tannenbaum, C., Martin, P., Tamblyn, R., Benedetti, A., & Ahmed, S. (2014) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2014.949 · Cited by 665
Meta-analysis of benzodiazepine use in the treatment of insomnia.
(2000) · PubMed Central · Cited by 613
Centre for Evidence Based Medicine
Badenoch, D., & Mbe (2003) · Cited by 586
Benzodiazepines revisited—will we ever learn?
Lader, M. (2011) · Addiction · doi:10.1111/j.1360-0443.2011.03563.x · Cited by 573
Association of road-traffic accidents with benzodiazepine use
Barbone, F., McMahon, A., Davey, P., Morris, A. D., Reid, I., McDevitt, D., & MacDonald, T. M. (1998) · The Lancet · doi:10.1016/s0140-6736(98)04087-2 · Cited by 555
Patient Barriers to and Enablers of Deprescribing: a Systematic Review
Reeve, E., To, J., Hendrix, I., Shakib, S., Roberts, M. S., & Wiese, M. D. (2013) · Drugs & Aging · doi:10.1007/s40266-013-0106-8 · Cited by 536
Reeve, E., Shakib, S., Hendrix, I., Roberts, M. S., & Wiese, M. D. (2014) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.12386 · Cited by 397
Using scoping literature reviews as a means of understanding and interpreting existing literature
Rumrill, P. D., Fitzgerald, S. M., & Merchant, W. R. (2010) · WORK: A Journal of Prevention, Assessment & Rehabilitation · doi:10.3233/wor-2010-0998 · Cited by 358
Morin, C. M., Bastien, C., Guay, B., Radouco-Thomas, M., Leblanc, J., & Vallières, A. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.2.332 · Cited by 348
Kastner, M., Tricco, A. C., Soobiah, C., Lillie, E., Perrier, L., Horsley, T., Welch, V., Cogo, E., Antony, J., & Straus, S. E. (2012) · BMC Medical Research Methodology · doi:10.1186/1471-2288-12-114 · Cited by 345
Withdrawing Benzodiazepines in Primary Care
Lader, M., Tylee, A., & Donoghue, J. (2009) · CNS Drugs · doi:10.2165/0023210-200923010-00002 · Cited by 318
Holm, K. J., & Goa, K. L. (2000) · Drugs · doi:10.2165/00003495-200059040-00014 · Cited by 317
The Global Evidence Mapping Initiative: Scoping research in broad topic areas
Bragge, P., Clavisi, O., Turner, T., Tavender, E., Collie, A., & Gruen, R. L. (2011) · BMC Medical Research Methodology · doi:10.1186/1471-2288-11-92 · Cited by 310
Deprescribing: Achieving Better Health Outcomes for Older People through Reducing Medications
Woodward, M. C. (2003) · Journal of Pharmacy Practice and Research · doi:10.1002/jppr2003334323 · Cited by 297
Overview of a formal scoping review on health system report cards
Brien, S. E., Lorenzetti, D. L., Lewis, S., Kennedy, J., & Ghali, W. A. (2010) · Implementation Science · doi:10.1186/1748-5908-5-2 · Cited by 290
Ohayon, M. M., & Lader, M. H. (2002) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v63n0912 · Cited by 271
(1993) · American Journal of Psychiatry · doi:10.1176/ajp.150.10.1485 · Cited by 263
How do primary care physicians seek answers to clinical questions? A literature review.
Coumou, H. C. H., & Meijman, F. J. (2006) · PubMed · Cited by 255
Albrecht, L., Archibald, M., Arseneau, D., & Scott, S. D. (2013) · Implementation Science · doi:10.1186/1748-5908-8-52 · Cited by 252
Benzodiazepine Use and Hip Fractures in the Elderly
Wagner, A. K., Zhang, F., Soumerai, S. B., Walker, A. M., Gurwitz, J. H., Glynn, R. J., & Ross‐Degnan, D. (2004) · Archives of Internal Medicine · doi:10.1001/archinte.164.14.1567 · Cited by 243
Trends in psychotropic medication use among U.S. adults
Paulose‐Ram, R., Safran, M. A., Jonas, B. S., Gu, Q., & Orwig, D. (2007) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.1367 · Cited by 215
Ford, E. S., Wheaton, A. G., Cunningham, T. J., Giles, W. H., Chapman, D. P., & Croft, J. B. (2014) · Sleep · doi:10.5665/sleep.3914 · Cited by 213
Effectiveness of current treatment approaches for benzodiazepine discontinuation: a meta‐analysis
Parr, J. M., Kavanagh, D. J., Cahill, L., Mitchell, G., & Young, R. M. (2009) · Addiction · doi:10.1111/j.1360-0443.2008.02364.x · Cited by 212
Dell’osso, B., & Lader, M. (2013) · European Psychiatry · doi:10.1016/j.eurpsy.2011.11.003 · Cited by 210
Strategies for discontinuing long-term benzodiazepine use: Meta-analysis
Voshaar, R. C. O., Couvée, J. E., Van Balkom, A. J. L. M., Mulder, P. G. H., & Zitman, F. G. (2006) · British Journal of Psychiatry · doi:10.1192/bjp.189.3.213 · Cited by 205
(2013) · Europe PMC (PubMed Central) · Cited by 200
Long-term Therapeutic Use of Benzodiazepines: II. Effects of Gradual Taper
Schweizer, E. (1990) · Archives of General Psychiatry · doi:10.1001/archpsyc.1990.01810220024003 · Cited by 191
CURRAN, H. V., COLLINS, R., FLETCHER, S., KEE, S. C. Y., WOODS, B., & ILIFFE, S. (2003) · Psychological Medicine · doi:10.1017/s0033291703008213 · Cited by 190
Klein, E. (2002) · PubMed · Cited by 182
Lemoine, P., Kermadi, I., Garcia-Acosta, S., Garay, R. P., & Dib, M. (2006) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2005.08.015 · Cited by 180
Medication use and risk of falls
Neutel, C. I., Perry, S., & Maxwell, C. J. (2002) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.686 · Cited by 177
(2003) · Europe PMC (PubMed Central) · Cited by 176
Discontinuation of alprazolam treatment in panic patients
(1987) · American Journal of Psychiatry · doi:10.1176/ajp.144.3.303 · Cited by 172
Benzodiazepine dependence and withdrawal: a review of the syndrome and its clinical management
Schweizer, E., & Rickels, K. (1998) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1998.tb05973.x · Cited by 163 · cited 1×
“articles or guidelines were included (Additional file 3) [8, 43–180].”
BackgroundPatterns and correlates of benzodiazepine use in the French general population
Lagnaoui, R., Depont, F., Fourrier, A., Abouelfath, A., B�gaud, B., Verdoux, H., & Moore, N. D. (2004) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-004-0808-2 · Cited by 160
Liesegang, T. J. (2001) · American Journal of Ophthalmology · doi:10.1016/s0002-9394(00)00911-9 · Cited by 155
Voshaar, R. C. O., Gorgels, W. J. M. J., Mol, A. J. J., Van Balkom, A. J. L. M., Van De Lisdonk, E. H., Breteler, M. H. M., Van Den Hoogen, J. M., & Zitman, F. G. (2003) · British Journal of Psychiatry · doi:10.1192/bjp.182.6.498 · Cited by 154
Canadian Study of Health and Aging
Eastwood, R., Nobbs, H., Lindsay, J., & McDowell, I. (1992) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000107019 · Cited by 153
The Epidemiology of Long-Term Benzodiazepine Use
Neutel, C. I. (2005) · International Review of Psychiatry · doi:10.1080/09540260500071863 · Cited by 148
Bashir, K., King, M., & Ashworth, M. J. (1994) · Europe PMC (PubMed Central) · Cited by 143
Schweizer, E. (1991) · Archives of General Psychiatry · doi:10.1001/archpsyc.1991.01810290060012 · Cited by 138
Michelini, S., Cassano, G. B., Frare, F., & Perugi, G. (2007) · Pharmacopsychiatry · doi:10.1055/s-2007-979558 · Cited by 136
Evaluation of an easy, cost-effective strategy for cutting benzodiazepine use in general practice.
Cormack, M., Sweeney, K., Hughes-Jones, H., & Foot, G. A. (1994) · Europe PMC (PubMed Central) · Cited by 131
Sirdifield, C., Anthierens, S., Creupelandt, H., Chipchase, S. Y., Christiaens, T., & Siriwardena, A. N. (2013) · BMC Family Practice · doi:10.1186/1471-2296-14-191 · Cited by 131
Facilitation of Benzodiazepine Discontinuation by Melatonin
Garfinkel, D., Zisapel, N., Wainstein, J., & Laudon, M. (1999) · Archives of Internal Medicine · doi:10.1001/archinte.159.20.2456 · Cited by 127
GPs’ management strategies for patients with insomnia: A survey and qualitative interview study
Everitt, H., McDermott, L., Leydon, G., Yules, H., Baldwin, D., & Little, P. (2014) · British Journal of General Practice · doi:10.3399/bjgp14x677176 · Cited by 127
Keck, P. E., McElroy, S. L., & Friedman, L. (1992) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199202001-00006 · Cited by 125
Mugunthan, K., McGuire, T., & Glasziou, P. (2011) · British Journal of General Practice · doi:10.3399/bjgp11x593857 · Cited by 123
Gosselin, P., Ladouceur, R., Morin, C. M., Dugas, M. J., & Baillargeon, L. (2006) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.74.5.908 · Cited by 122 · cited 1×
“articles or guidelines were included (Additional file 3) [8, 43–180].”
BackgroundVicens, C., Bejarano, F., Sempere, E., Mateu, C., Fiol, F., Socias, I., Aragonès, E., Palop, V., Beltran, J. L., Piñol, J. L., et al. (2014) · British Journal of Psychiatry · doi:10.1192/bjp.bp.113.134650 · Cited by 122
The benefits and harms of deprescribing
Reeve, E., Shakib, S., Hendrix, I., Roberts, M. S., & Wiese, M. D. (2014) · The Medical Journal of Australia · doi:10.5694/mja13.00200 · Cited by 115
Benzodiazepine withdrawal: Overview and implications for the treatment of anxiety
Roy‐Byrne, P., & Hommer, D. (1988) · The American Journal of Medicine · doi:10.1016/0002-9343(88)90309-9 · Cited by 115
Clinical management of benzodiazepine dependence.
Higgitt, A., LADER, M. H., & Fonagy, P. (1985) · BMJ · doi:10.1136/bmj.291.6497.688 · Cited by 112
Cunningham, C. M., Hanley, G. E., & Morgan, S. (2010) · Health Policy · doi:10.1016/j.healthpol.2010.03.008 · Cited by 111
The treatment of benzodiazepine dependence
ASHTON, H. (1994) · Addiction · doi:10.1111/j.1360-0443.1994.tb03755.x · Cited by 110
Rickels, K., DeMartinis, N., García-España, F., Greenblatt, D. J., Mandos, L. A., & Rynn, M. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.12.1973 · Cited by 110
Cook, J. M., Biyanova, T., Masci, C., & Coyne, J. C. (2007) · Journal of General Internal Medicine · doi:10.1007/s11606-007-0205-5 · Cited by 107
Trends in potentially inappropriate prescribing amongst older UK primary care patients
Wilde, S. D., Carey, I. M., Harris, T. J., Richards, N., Victor, C. R., Hilton, S. R., & Cook, D. G. (2006) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.1306 · Cited by 106
Murphy, S. M., & Tyrer, P. (1991) · British Journal of Psychiatry · doi:10.1192/bjp.158.4.511 · Cited by 104
Sulser, F. (1987) · PubMed · Cited by 98
Otto, M. W., McHugh, R. K., Simon, N. M., Farach, F. J., Worthington, J. J., & Pollack, M. H. (2010) · Behaviour Research and Therapy · doi:10.1016/j.brat.2010.04.002 · Cited by 95
Lai, H., Hwang, S., Chen, Y., Chen, T., Lin, M.-H., & Chen, L. (2009) · Clinical Therapeutics · doi:10.1016/j.clinthera.2009.08.023 · Cited by 94
Pringsheim, T. M., & Gardner, D. M. (2014) · CMAJ Open · doi:10.9778/cmajo.20140009 · Cited by 94
Self-citationHogan, D. B., Maxwell, C. J., Fung, T. S., & Ebly, E. M. (2003) · PubMed · Cited by 92
Valaitis, R. K., Martin‐Misener, R., Wong, S. T., MacDonald, M., Meagher-Stewart, D. M., Austin, P., Kaczorowski, J. A., O’Mara, L., & Savage, R. (2012) · Primary Health Care Research & Development · doi:10.1017/s1463423611000594 · Cited by 92
Benzodiazepine withdrawal: a review of the evidence.
Noyes, R., Garvey, M. J., Cook, B. L., & Perry, P. J. (1988) · PubMed · Cited by 87
Use of Benzodiazepines in the Community
Olfson, M. (1994) · Archives of Internal Medicine · doi:10.1001/archinte.1994.00420110079009 · Cited by 84
Doctors’ Perceptions and Use of Evidence-Based Medicine
Swennen, M. H. J., van der Heijden, G. J. M. G., Boeije, H., van Rheenen, N., Verheul, F., van der Graaf, Y., & Kalkman, C. J. (2013) · Academic Medicine · doi:10.1097/acm.0b013e31829ed3cc · Cited by 82
Benzodiazepine Withdrawal Syndrome: A Literature Review and Evaluation
Mackinnon, G. L., & Parker, W. A. (1982) · The American Journal of Drug and Alcohol Abuse · doi:10.3109/00952998209002608 · Cited by 81
Smith, A. J., & Tett, S. E. (2010) · BMC Health Services Research · doi:10.1186/1472-6963-10-321 · Cited by 81
Rickels, K., Schweizer, E. E., España, F. G., Case, G. W., DeMartinis, N. A., & Greenblatt, D. J. (1999) · Psychopharmacology · doi:10.1007/s002130050798 · Cited by 80
Failure of buspirone to manage benzodiazepine withdrawal
Schweizer, E. E., & Rickels, K. (1986) · American Journal of Psychiatry · doi:10.1176/ajp.143.12.1590 · Cited by 79
A Comparison of Buspirone and Placebo in Relieving Benzodiazepine Withdrawal Symptoms
LADER, M., & OLAJIDE, D. (1987) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-198702000-00003 · Cited by 79
Can valerian improve the sleep of insomniacs after benzodiazepine withdrawal?
Poyares, D. R., Guilleminault, C., Ohayon, M. M., & Tufik, S. B. (2002) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/s0278-5846(01)00305-0 · Cited by 77
Hypnotic taper with or without self-help treatment of insomnia: A randomized clinical trial.
Belleville, G., Guay, C., Guay, B., & Morin, C. M. (2007) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.75.2.325 · Cited by 77
Heather, N., Bowie, A., Ashton, H., McAvoy, B., Spencer, I., Brodie, J., & Giddings, D. (2004) · Addiction Research & Theory · doi:10.1080/1606635310001634528 · Cited by 77
IS THERE A RATIONALE FOR PRESCRIPTION OF BENZODIAZEPINES IN THE ELDERLY? REVIEW OF THE LITERATURE
Petrovic, M., Mariman, A., Warie, H., Afschrift, M., & Pevernagie, D. (2003) · Acta Clinica Belgica · doi:10.1179/acb.2003.58.1.004 · Cited by 76
Benzodiazepine Dependence: Avoidance and Withdrawal
Marriott, S., & Tyrer, P. (1993) · Drug Safety · doi:10.2165/00002018-199309020-00003 · Cited by 73
Mental Health-Related Drug Utilization Among Older Adults: Prevalence, Trends, and Costs
Mamdani, M., Rapoport, M., Shulman, K. I., Herrmann, N., & Rochon, P. A. (2005) · American Journal of Geriatric Psychiatry · doi:10.1176/appi.ajgp.13.10.892 · Cited by 70
Withdrawal from long-term benzodiazepine use: randomised trial in family practice.
(2006) · PubMed Central · Cited by 67
Cantopher, T., Olivieri, S., Cleave, N., & Edwards, J. G. (1990) · British Journal of Psychiatry · doi:10.1192/bjp.156.3.406 · Cited by 67
Hadley, S. J., Mandel, F. S., & Schweizer, E. (2012) · Journal of Psychopharmacology · doi:10.1177/0269881111405360 · Cited by 66
Use of benzodiazepines and related drugs in Manitoba: a population-based study
Alessi‐Severini, S., Bolton, J. M., Enns, M. W., Dahl, M. E., Collins, D. M., Chateau, D. G., & Sareen, J. (2014) · CMAJ Open · doi:10.9778/cmajo.20130076 · Cited by 66
Ashton, C. H., Rawlins, M. D., & Tyrer, S. P. (1990) · British Journal of Psychiatry · doi:10.1192/bjp.157.2.232 · Cited by 66 · cited 1×
“articles or guidelines were included (Additional file 3) [8, 43–180].”
BackgroundPharmacologic Strategies for Discontinuing Benzodiazepine Treatment
Rickels, K., DeMartinis, N. A., Rynn, M. A., & Mandos, L. A. (1999) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199912002-00003 · Cited by 65
Singh, J. P. (2005) · Indian Journal of Pharmacology · doi:10.4103/0253-7613.15121 · Cited by 58
Bobes, J., Rubio, G., Terán, A., Cervera, G., López-Gómez, V., Vilardaga, I., & Pérez, M. (2012) · European Psychiatry · doi:10.1016/j.eurpsy.2010.12.004 · Cited by 57
Anxiety disorders and the use and abuse of drugs.
Calabrese, J. R., & Delucchi, G. A. (1989) · PubMed · Cited by 56
Lähteenmäki, R., Puustinen, J., Vahlberg, T., Lyles, A., Neuvonen, P. J., Partinen, M., Räihä, I., & Kivelä, S.-L. (2014) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.12294 · Cited by 54
Generalized anxiety disorder: new concepts and psychopharmacologic therapies.
Dubovsky, S. L. (1990) · PubMed · Cited by 54
Schweizer, E. E., CASE, W. G., España, F. G., Rickels, K., & Greenblatt, D. J. (1995) · Psychopharmacology · doi:10.1007/bf02246214 · Cited by 53
Taylor, D. J., Schmidt-Nowara, W. W., Jessop, C. A., & Ahearn, J. (2010) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.27767 · Cited by 52
Peles, E., Hetzroni, T., Bar‐Hamburger, R., Adelson, M., & Schreiber, S. (2007) · Addiction · doi:10.1111/j.1360-0443.2007.02007.x · Cited by 52
Comparing patterns of long‐term benzodiazepine use between a Dutch and a Swedish community
van Hulten, R., Isacson, D. G. L., Bakker, A., & Leufkens, H. G. M. (2002) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.784 · Cited by 50
Otto, M. W., Hong, J. P., & Safren, S. A. (2002) · Current Pharmaceutical Design · doi:10.2174/1381612023396726 · Cited by 49
Morin, C. M., Colecchi, C. A., Ling, W. D., & Sood, R. K. (1995) · Behavior Therapy · doi:10.1016/s0005-7894(05)80042-5 · Cited by 49
Deprescribing: a new word to guide medication review
Frank, C. (2014) · Canadian Medical Association Journal · doi:10.1503/cmaj.131568 · Cited by 49
Psychological strategies for discontinuing benzodiazepine treatment.
Spiegel, D. A. (1999) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199912002-00004 · Cited by 49
Treatment of out-patients with complicated benzodiazepine dependence: Comparison of two approaches
Vorma, H., Naukkarinen, H., Sarna, S., & Kuoppasalmi, K. (2002) · Addiction · doi:10.1046/j.1360-0443.2002.00129.x · Cited by 46
A Controlled Trial of Dothiepin and Placebo in Treating Benzodiazepine Withdrawal Symptoms
Tyrer, P. J., Ferguson, B., Hallström, C., Michie, M. H., Tyrer, S. P., Cooper, S. J., Caplan, R., & Barczak, P. (1996) · The British Journal of Psychiatry · doi:10.1192/bjp.168.4.457 · Cited by 46
Understanding and treating depression in anxious patients.
Dubovsky, S. L. (1990) · PubMed · Cited by 45
Identification and management of benzodiazepine dependence.
Tyrer, P. J., & Seivewright, N. (1984) · PubMed · Cited by 45
O'Connor, K., Marchand, A., Brousseau, L., Aardema, F., Mainguy, N., Landry, P., Savard, P., Léveillé, C., Lafrance, V., Boivin, S., et al. (2008) · Clinical Psychology & Psychotherapy · doi:10.1002/cpp.556 · Cited by 44
(1994) · American Journal of Psychiatry · doi:10.1176/ajp.151.12.1760 · Cited by 44
Are there guidelines for the responsible prescription of benzodiazepines?
el-Guebaly, N., Sareen, J., & Stein, M. B. (2010) · The Canadian Journal of Psychiatry · doi:10.1177/070674371005501104 · Cited by 42
Tapering Clonazepam in Patients With Panic Disorder After at Least 3 Years of Treatment
Nardi, A. E., Freire, R. C. R., Valença, A. M., Amrein, R., de Cerqueira, A. C. R., Lopes, F. L., Nascimento, I., Mezzasalma, M. A., Veras, A. B., Sardinha, A., et al. (2010) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0b013e3181dcb2f3 · Cited by 41
Viswanathan, M., Berkman, N. D., Dryden, D. M., & Hartling, L. G. (2013) · Cited by 41
A Controlled Trial of Ondansetron, a 5-HT3 Antagonist, in Benzodiazepine Discontinuation
Romach, M. K., Kaplan, H. L., Busto, U. E., Somer, G. R., & Sellers, E. M. (1998) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199804000-00004 · Cited by 40
Current and future applications of SPECT in clinical psychiatry.
Ballenger, J. C., Pecknold, J., Rickels, K., & Sellers, E. M. (1992) · PubMed · Cited by 39
Woodward, M. C. (1999) · CNS Drugs · doi:10.2165/00023210-199911040-00003 · Cited by 38
Psychological alternatives to long-term benzodiazepine use.
Cormack, M., & Sinnott, A. (1983) · PubMed · Cited by 37
Nakao, M., Takeuchi, T., Nomura, K., Teramoto, T., & Yano, E. (2006) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2006.01565.x · Cited by 37
Kunz, D., Bineau, S., Maman, K., Milea, D., & Toumi, M. (2012) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2012.638284 · Cited by 37 · cited 1×
“articles or guidelines were included (Additional file 3) [8, 43–180].”
BackgroundIs Melatonin Helpful in Stopping the Long-Term Use of Hypnotics? A Discontinuation Trial
Vissers, F. H. J. A., Knipschild, P. G., & Crebolder, H. F. J. M. (2007) · Pharmacy World & Science · doi:10.1007/s11096-007-9118-y · Cited by 36
Kravitz, R. L., & Bell, R. A. (2013) · BMC Medical Informatics and Decision Making · doi:10.1186/1472-6947-13-s3-s5 · Cited by 34
Benzodiazepine withdrawal in general practice.
(1982) · PubMed Central · Cited by 33
Cognitive-behavioral therapy for benzodiazepine discontinuation in panic disorder patients.
Otto, M. W., Pollack, M. H., Meltzer-Brody, S. E., & Rosenbaum, J. F. (1992) · PubMed · Cited by 33
Discontinuation reactions to alprazolam in panic disorder
Pecknold, J. C. (1993) · Journal of Psychiatric Research · doi:10.1016/0022-3956(93)90025-w · Cited by 32
Sanchez‐Craig, M., Cappell, H., Busto, U. E., & Kay, G. (1987) · British Journal of Addiction · doi:10.1111/j.1360-0443.1987.tb00434.x · Cited by 30
The effects of substituting zopiclone in withdrawal from chronic use of benzodiazepine hypnotics
Pat‐Horenczyk, R., Hacohen, D., Herer, P., & Lavie, P. (1998) · Psychopharmacology · doi:10.1007/s002130050789 · Cited by 29
Analysis of benzodiazepine withdrawal program managed by primary care nurses in Spain
Lopez-Peig, C., Mundet, X., Casabella, B., del Val, J. D., Lacasta, D., & Diògene, E. (2012) · BMC Research Notes · doi:10.1186/1756-0500-5-684 · Cited by 28
Management of Hypnotic Discontinuation in Chronic Insomnia
Bélanger, L., Belleville, G., & Morin, C. (2009) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2009.07.011 · Cited by 28
Stewart, R. E., Niessen, W., Broer, J., Snijders, T. A. B., Haaijer‐Ruskamp, F. M., & Jong, B. M. (2007) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2006.11.024 · Cited by 28
Martinsson, G., Fagerberg, I., Gustin, L. W., & Lindholm, C. (2012) · BMC Psychiatry · doi:10.1186/1471-244x-12-197 · Cited by 26
Patterns of benzodiazepine use in a Canadian population sample
Esposito, E., Barbui, C., & Patten, S. B. (2009) · Epidemiologia e Psichiatria Sociale · doi:10.1017/s1121189x00000531 · Cited by 26
Long-term pharmacologic treatment of panic disorder.
Ballenger, J. C. (1991) · PubMed · Cited by 26
Murphy, A. L., Fleming, M., Martin‐Misener, R., SKETRIS, I. S., MacCara, M. E., & Gass, D. A. (2006) · BMC Nursing · doi:10.1186/1472-6955-5-5 · Cited by 25
Self-citationWithdrawal from benzodiazepines by initially switching to zopiclone
Shapiro, C. M., Sherman, D., & Df, P. (1995) · European Psychiatry · doi:10.1016/0924-9338(96)80096-4 · Cited by 25
Benzodiazepine dependence and withdrawal: identification and medical management.
Landry, M. J., Smith, D. E., Mcduff, D. R., & Baughman, O. L. (1992) · PubMed · Cited by 25
The role of captodiamine in the withdrawal from long-term benzodiazepine treatment
Mercier-Guyon, C., Chabannes, J. P., & Saviuc, P. (2004) · Current Medical Research and Opinion · doi:10.1185/030079904125004457 · Cited by 24
The discomfort of an evidence‐based prescribing decision
Lewis, P. J., & Tully, M. P. (2009) · Journal of Evaluation in Clinical Practice · doi:10.1111/j.1365-2753.2009.01250.x · Cited by 24
What's wrong with prescribing hypnotics?
(2004) · Drug and Therapeutics Bulletin · doi:10.1136/dtb.2004.421289 · Cited by 24
Long-term anxiolytic therapy: the issue of drug withdrawal.
Lader, M. (1987) · PubMed · Cited by 24
Panic control treatment and its applications.
Hofmann, S. G., & Spiegel, D. A. (1999) · PubMed Central · Cited by 23
Rynn, M., García-España, F., Greenblatt, D. J., Mandos, L. A., Schweizer, E., & Rickels, K. (2003) · Journal of Clinical Psychopharmacology · doi:10.1097/01.jcp.0000088907.24613.3f · Cited by 23
The benzodiazepine withdrawal syndrome and its management.
Onyett, S. (1989) · Europe PMC (PubMed Central) · Cited by 22
McIntosh, B., Clark, M., & Spry, C. (2011) · Cited by 22
Lemoine, P., Allain, H., Janus, C., & Sutet, P. (1995) · European Psychiatry · doi:10.1016/0924-9338(96)80098-8 · Cited by 21
A practical approach to benzodiazepine discontinuation
DuPont, R. L. (1990) · Journal of Psychiatric Research · doi:10.1016/0022-3956(90)90039-s · Cited by 20
(1990) · PubMed · Cited by 19
van de Steeg-van Gompel, C. H. P. A., Wensing, M., & De Smet, P. A. G. M. (2009) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2008.07.009 · Cited by 19
Alcohol and other drug withdrawal: practice guidelines.
Kenny, P., Swan, A., Berends, L., Jenner, L., Hunter, B., & Mugavin, J. (2009) · Cited by 18
Benzodiazepine research: Current findings and practical consequences
Hayward, P., Wardle, J., & Higgitt, A. (1989) · British Journal of Clinical Psychology · doi:10.1111/j.2044-8260.1989.tb00835.x · Cited by 18
Short-acting versus long-acting benzodiazepines: Discontinuation effects in panic disorders
Burrows, G. D., Norman, T. R., Judd, F. K., & Marriott, P. F. (1990) · Journal of Psychiatric Research · doi:10.1016/0022-3956(90)90037-q · Cited by 18
Onyett, S., & Turpin, G. (1988) · Behavioural and Cognitive Psychotherapy · doi:10.1017/s0141347300014154 · Cited by 17
Benzodiazepine dependent patients and their psychological treatment
Crouch, G., Robson, M., & Hallström, C. (1988) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/0278-5846(88)90109-1 · Cited by 16
The treatment of tranquilizer dependence by propranolol.
Hallström, C., Crouch, G., Robson, M., & Shine, P. J. (1988) · PubMed · Cited by 16
A comparison of alpidem and placebo in relieving benzodiazepine withdrawal symptoms
Lader, M. H., Farr, I., & Morton, S. (1993) · International Clinical Psychopharmacology · doi:10.1097/00004850-199300810-00005 · Cited by 15
The efficacy of complaints management training in facilitating benzodiazepine withdrawal
Elsesser, K., Sartory, G., & Maurer, J. (1996) · Behaviour Research and Therapy · doi:10.1016/0005-7967(95)00051-8 · Cited by 15
Smolders, M., Laurant, M., van Rijswijk, E., Mulder, J., Braspenning, J., Verhaak, P., Wensing, M., & Grol, R. (2007) · Family Practice · doi:10.1093/fampra/cmm062 · Cited by 15
Alternative treatments for withdrawing the long-term benzodiazepine user: a pilot study
Nathan, R. G., Robinson, D., Cherek, D. R., Sebastian, C. S., Hack, M., & Davison, S. (1986) · International Journal of the Addictions · doi:10.3109/10826088609063450 · Cited by 14
Adjunctive treatment of benzodiazepine discontinuation syndromes: A review
Roy‐Byrne, P., Sullivan, M. D., Cowley, D. S., & Ries, R. K. (1993) · Journal of Psychiatric Research · doi:10.1016/0022-3956(93)90024-v · Cited by 13
Use of zolpidem 10 mg as a benzodiazepine substitute in 84 patients with insomnia
Allain, H., Coz, F. L., Borderies, P., Schück, S., Giclais, B. D. L., Patat, A. A., & Gandon, J. M. (1998) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/(sici)1099-1077(1998120)13:8 · Cited by 13
Monitoring seizure duration during ECT.
Kramer, B. A., Pollock, V. E., & Schneider, L. S. (1990) · PubMed · Cited by 13
Continuation treatment of panic disorder with high-potency benzodiazepines.
Davidson, J. R. T. (1990) · PubMed · Cited by 12
Patient-controlled benzodiazepine dose reduction in a community mental health service
Raju, B., & Meagher, D. J. (2005) · Irish Journal of Psychological Medicine · doi:10.1017/s0790966700008909 · Cited by 12
Patten, S. B., Williams, J. V. A., Lavorato, D. H., Kassam, A., & Sabapathy, C. D. (2010) · The Canadian Journal of Psychiatry · doi:10.1177/070674371005501207 · Cited by 11
Benzodiazepine withdrawal: A pilot comparison of three methods
Fraser, D., Peterkin, G. S. D., Gamsu, C. V., & Baldwin, P. J. (1990) · British Journal of Clinical Psychology · doi:10.1111/j.2044-8260.1990.tb00875.x · Cited by 11
The Use of Benzodiazepines in the Workplace
Roy‐Byrne, P., & Cowley, D. S. (1990) · Journal of Psychoactive Drugs · doi:10.1080/02791072.1990.10472220 · Cited by 11
Abelson, J. L., & Curtis, G. C. (1993) · Journal of Anxiety Disorders · doi:10.1016/0887-6185(93)90009-a · Cited by 10
Buspirone treatment as an aid to benzodiazepine withdrawal
Morton, S., & Lader, M. (1995) · Journal of Psychopharmacology · doi:10.1177/026988119500900407 · Cited by 10
Hypnotics. Options to help your patients stop.
Woodward, M. (2000) · PubMed · Cited by 10
Chung, K., Cheung, R. C., & Tam, J. W. (1999) · PubMed · Cited by 9
A Self-Help Handout for Benzodiazepine Discontinuation Using Cognitive Behavioral Therapy
Ahmed, M. S., Westra, H. A., & Stewart, S. H. (2008) · Cognitive and Behavioral Practice · doi:10.1016/j.cbpra.2007.05.003 · Cited by 8
What happens when doctors stop prescribing temazepam? Use of alternative therapies.
Gilhooly, T., Webster, M. G., Poole, N., & Ross, S. (1998) · Europe PMC (PubMed Central) · Cited by 7
Drake, J. (1991) · Current Medical Research and Opinion · doi:10.1185/03007999109111509 · Cited by 7
Managing long-term therapy for panic disorder.
Burrows, G. D. (1990) · PubMed · Cited by 6
Benzodiazepines: dependence and a therapeutic approach to gradual withdrawal.
Blais, D., & Petit, L. (1990) · PubMed · Cited by 5
Use of benzodiazepines in psychiatry.
Harangozó, J., Magyar, I., & Faludy, G. (1991) · PubMed · Cited by 3
Moderating Benzodiazepine Use in the Elderly: Curbing physicians' prescribing practices.
Huston, P. (1992) · PubMed · Cited by 3
Strategies for Benzodiazepine Withdrawal in Seniors
Chang, F. (2005) · Canadian Pharmacists Journal / Revue des Pharmaciens du Canada · doi:10.1177/171516350513800804 · Cited by 3
Consider This Slow-Taper Program for Benzodiazepines
Thirtala, T., Kaur, K., Karlapati, S. K., & Lippmann, S. (2013) · Current psychiatry · Cited by 1
Research works printed but not linked: 11
- Ballenger JC, Pecknold J, Rickels K, Sellers EM. Medication discontinuation in panic disorder. J Clin Psychiatry. 1993;54 Suppl 10:15–21.
- Bartholomew S. Benzodiazepine dependence in the elderly. J Am Acad Phys Assist. 1990;3:535–9.
- Choy Y. Managing side effects of anxiolytics. Primary Psychiatry. 2007;14:68–76.
- Benzodiazepines: good practice guidelines for clinicians. Department of Health and Children, Ireland. 2002. http://hdl.handle.net/10147/46748 . Accessed 19 Jan 2014.
- DuPont RL. Thinking about stopping treatment for panic disorder. J Clin Psychiatry. 1990;51:38–45.
- Huston PG. Moderating benzodiazepine use in the elderly. Can Fam Phys. 1992;38:2459–67.
- Jensen B. Benzodiazepine comparison chart. In: Jensen B, Regier L, editors. RxFiles Drug Comparison Charts. 9th ed. Saskatoon: Saskatoon Health Region; 2013. p. 101.
- Management options for improving sleep. National Prescribing Service. 2010. http://www.nps.org.au/publications/health-professional/prescribing-practice-review/2010/prescribing-practice-review-49 . Accessed 31 Mar 2014.
- Saul PA, Korlipara K, Presley P. A randomised, multicentre, double-blind, comparison of atenolol and placebo in the control of benzodiazepine withdrawal symptoms. Acta Ther. 1989;15:117–23.
- Sloan E. Medication and substance use: keeping insomnia treatment safe. Insomnia Rounds. 2013;2:1–6.
- Zee P, Wang-Weigand S, Roth T. Facilitation of zolpidem discontinuation using ramelteon in subjects with chronic insomnia. Am J Addict. 2011;20:380–1.
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Metadata
- Authors
- Pollmann, A. S., Murphy, A. L., Bergman, J. C., & Gardner, D. M.
- Affiliations
- Dalhousie University (CA)
- Corresponding author
- Pollmann, André S.
- Venue
- BMC Pharmacology and Toxicology
- Published
- 2015-07-04
- Volume
- 16
- Issue
- 1
- Pages
- 19-19
- ISSN
- 2050-6511 (ISSN-L)
- PMC
- PMC4491204
- OpenAlex
- W2170043108
- Cited by
- 114
- References
- 189
- Citations by year
- 2026: 7 · 2025: 7 · 2024: 7 · 2023: 14 · 2022: 18 · 2021: 16 · 2020: 6 · 2019: 13 · 2018: 16 · 2017: 6 · 2016: 4
- FWCI
- 4.34
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- BMC Pharmacology and Toxicology (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- Dalhousie University
- College of Pharmacy, Dalhousie University
- Topics
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Keywords
- deprescribing, benzodiazepines, Z-drugs, zopiclone, zolpidem, zaleplon, community-dwelling adults, benzodiazepine withdrawal, gradual dose reduction, behaviour change interventions, psychotherapy, realist synthesis
- MeSH terms
- Deprescriptions, Zolpidem, Acetamides, Benzodiazepines, Humans, Piperazines, Pyridines, Pyrimidines, Azabicyclo Compounds
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