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Cited by 526

The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.

Review of bone graft and bone substitutes with an emphasis on fracture surgeries

Open access
Sohn, Hoon-Sang, Oh, Jong-Keon·2019·Biomaterials Research
DOI 10.1186/s40824-019-0157-y
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Abstract

Background: Autogenous bone graft is the gold standard bone graft material. However, due to limitations of supply and morbidity associated with autograft harvest, various bone substitutes have been considered. This article aims to review the properties of the bone graft and various bone substitutes currently available in orthopedic surgery. Main body: Synthetic bone substitutes consist of hydroxyapatite, tricalcium phosphate, calcium sulfate, or a combination of these minerals. Synthetic porous substitutes share several advantages over allografts, including unlimited supply, easy sterilization, and storage. However, they also have some disadvantages, such as brittle properties, variable rates of resorption, and poor performance in some clinical conditions. Recently, attention has been drawn to osteoinductive materials, such as demineralized bone matrix and bone morphogenetic proteins. Conclusion: Despite tremendous efforts toward developing autograft alternatives, a single ideal bone graft substitute has not been developed. The surgeon should understand the properties of each bone graft substitute to facilitate appropriate selection in each specific clinical situation.

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Metadata

Authors
Sohn, H.-S., & Oh, J.-K.
Venue
Biomaterials Research
Publisher
American Association for the Advancement of Science (AAAS)
Published
2019-03-14
Volume
23
Issue
1
Pages
9-9
ISSN
  • 1226-4601 (ISSN-L)
  • 2055-7124
DOI
10.1186/s40824-019-0157-y
OpenAlex
W2941025505
Cited by
526
References
53
FWCI
15.84
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Review of bone graft and bone substitutes with an emphasis on fracture surgeries. https://app.cochat.ai/papers/10.1186/s40824-019-0157-y
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Sohn, H.-S., & Oh, J.-K. (2019). Review of bone graft and bone substitutes with an emphasis on fracture surgeries. Biomaterials Research. https://doi.org/10.1186/s40824-019-0157-y

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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