The role of growth hormone in T-cell development and reconstitution

Molecular and Cellular Aspects of the Insulin-Like Growth Factor I Receptor

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Normal growth and development in the absence of hepatic insulin-like growth factor I

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Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1

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Insulin-Like Growth Factor-Binding Proteins in Serum and Other Biological Fluids: Regulation and Functions*

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Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

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Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production

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Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism

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The X-ray structure of a growth hormone–prolactin receptor complex

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The Roles of Prolactin, Growth Hormone, Insulin-Like Growth Factor-I, and Thyroid Hormones in Lymphocyte Development and Function: Insights from Genetic Models of Hormone and Hormone Receptor Deficiency

Dorshkind, K. A., & Horseman, N. D. (2000) · Endocrine Reviews · doi:10.1210/edrv.21.3.0397 · Cited by 370 · see citing works

The growth factor requirements of STRO-1-positive human bone marrow stromal precursors under serum-deprived conditions in vitro

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GH, GH Receptor, GH Secretagogue Receptor, and Ghrelin Expression in Human T Cells, B Cells, and Neutrophils

Hattori, N., Saito, T., Yagyu, T., Jiang, B., Kitagawa, K., & Inagaki, C. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.9.7866 · Cited by 320 · see citing works

Zinc Mediation of the Binding of Human Growth Hormone to the Human Prolactin Receptor

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Effect of Growth Hormone and Dexamethasone on Lipolysis and Metabolism in Isolated Fat Cells of the Rat

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Receptor-specific induction of insulin-like growth factor I in human monocytes by advanced glycosylation end product-modified proteins.

Kirstein, M., Aston, C., Hintz, R. L., & Vlassara, H. (1992) · Journal of Clinical Investigation · doi:10.1172/jci115879 · Cited by 264 · see citing works

Regulation of immunity in rats by lactogenic and growth hormones

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Insulin-Like Growth Factor Receptors

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Regulation of humoral immunity in rats by pituitary hormones

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The Growth Hormone/Prolactin Receptor Family

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The Pit-1 transcription factor gene is a candidate for the murine Snell dwarf mutation

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A Newly Defined Property of Somatotropin: Priming of Macrophages for Production of Superoxide Anion

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Inhibition of lymphocyte proliferation by antibodies to prolactin 1

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Regulation of interleukin 2-driven T-lymphocyte proliferation by prolactin.

Clevenger, C. V., Russell, D. H., Appasamy, P. M., & Prystowsky, M. B. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.16.6460 · Cited by 193 · see citing works

Production of immunoreactive growth hormone by mononuclear leukocytes

Weigent, D. A., Baxter, J. B., Wear, W. E., Smith, L. R., Bost, K. L., & Blalock, J. E. (1988) · The FASEB Journal · doi:10.1096/fasebj.2.12.3044906 · Cited by 189 · see citing works

Insulin-like growth factor-I regulates pro-B cell differentiation

Landreth, K. S., Narayanan, R., & Dorshkind, K. A. (1992) · Blood · doi:10.1182/blood.v80.5.1207.1207 · Cited by 188 · see citing works

Requirement for phosphatidylinositol 3’-kinase to protect hemopoietic progenitors against apoptosis depends upon the extracellular survival factor

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Growth hormone and insulin-like growth factor-I stimulate hormonal function and proliferation of thymic epithelial cells

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RAPID EFFECTS OF GROWTH HORMONE ON AMINO ACID TRANSPORT AND PROTEIN SYNTHESIS*

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Differential effects of growth hormone and prolactin on murine T cell development and function.

Murphy, W. J., Durum, S. K., & Longo, D. (1993) · The Journal of Experimental Medicine · doi:10.1084/jem.178.1.231 · Cited by 132 · see citing works

Growth hormone augments superoxide anion secretion of human neutrophils by binding to the prolactin receptor.

Fu, Y. K., Arkins, S., Fuh, G., Cunningham, B. C., Wells, J. A., Fong, S., Cronin, M. J., Dantzer, R., & Kelley, K. W. (1992) · Journal of Clinical Investigation · doi:10.1172/jci115605 · Cited by 128 · see citing works

Role of neuroendocrine hormones in murine T cell development. Growth hormone exerts thymopoietic effects in vivo

Murphy, W. J., Durum, S. K., & Longo, D. (1992) · The Journal of Immunology · doi:10.4049/jimmunol.149.12.3851 · Cited by 127 · see citing works

The pituitary gland is required for protection against lethal effects of Salmonella typhimurium

Edwards, C. K., Yunger, L. M., Lorence, R. M., Dantzer, R., & Kelley, K. W. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.6.2274 · Cited by 127 · see citing works

Expression of type I insulin-like growth factor receptors on human peripheral blood mononuclear cells

Kooijman, R., Willems, M., de Haas, C. J. C., Rijkers, G. T., Schuurmans, A. L. G., van Buul-Offers, S. C., Heijnen, C. J., & ZEGERS, B. J. M. (1992) · Endocrinology · doi:10.1210/endo.131.5.1425423 · Cited by 126 · see citing works

Immunologic and hematologic effects of neuroendocrine hormones. Studies on DW/J dwarf mice

Murphy, W. J., Durum, S. K., Anver, M. R., & Longo, D. (1992) · The Journal of Immunology · doi:10.4049/jimmunol.148.12.3799 · Cited by 125 · see citing works

Insulin-Like Growth Factor-I Binds Selectively to Human Peripheral Blood Monocytes and B-Lymphocytes*

Stuart, C. A., Meehan, R. T., Neale, L. S., Cintrón, N. M., & Furlanetto, R. W. (1991) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-72-5-1117 · Cited by 122 · see citing works

Structural and functional characterization of the human T lymphocyte receptor for insulin-like growth factor I in vitro.

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Mutational analysis of the intracellular domain of the human growth hormone receptor

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Murine macrophages express abundant insulin-like growth factor-I class I Ea and Eb transcripts

Arkins, S., Rebeiz, N., Biragyn, A., Reese, D. L., & Kelley, K. W. (1993) · Endocrinology · doi:10.1210/endo.133.5.8404686 · Cited by 117 · see citing works

Insulin-like growth factor-1 potentiates expansion of interleukin-7- dependent pro-B cells

Gibson, L. F., Piktel, D., & Landreth, K. S. (1993) · Blood · doi:10.1182/blood.v82.10.3005.3005 · Cited by 115 · see citing works

Stimulation of monocyte chemotaxis by human growth hormone and its deactivation by somatostatin

Wiedermann, C. J., Reinisch, N., & Braunsteiner, H. (1993) · Blood · doi:10.1182/blood.v82.3.954.954 · Cited by 107 · see citing works

Growth hormone stimulation of normal and leukemic human T-lymphocyte proliferation in vitro

Mercola, K., Cline, M., & Golde, D. W. (1981) · Blood · doi:10.1182/blood.v58.2.337.337 · Cited by 106 · see citing works

The effect of hypophysectomy upon the involution of the thymus in the rat

Smith, P. E. (1930) · The Anatomical Record · doi:10.1002/ar.1090470110 · Cited by 106 · see citing works

Effects of Insulin-Like Growth Factor Administration and Bone Marrow Transplantation on Thymopoiesis in Aged Mice 1

Montecino‐Rodriguez, E., CLARK, R. G., & Dorshkind, K. A. (1998) · Endocrinology · doi:10.1210/endo.139.10.6263 · Cited by 105 · see citing works

In vivo administration of recombinant growth hormone or gamma interferon activities macrophages: enhanced resistance to experimental Salmonella typhimurium infection is correlated with generation of reactive oxygen intermediates

Edwards, C. K., Ghiasuddin, S. M., Yunger, L. M., Lorence, R. M., Arkins, S., Dantzer, R., & Kelley, K. W. (1992) · Infection and Immunity · doi:10.1128/iai.60.6.2514-2521.1992 · Cited by 104 · see citing works

Growth Hormone Mediates the Growth of TLymphoblast Cell Lines via Locally Generated Insulin-Like Growth Factor-I*

Geffner, M. E., Bersch, N., Lippe, B. M., Rosenfeld, R. G., Hintz, R. L., & Golde, D. W. (1990) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-71-2-464 · Cited by 104 · see citing works

The effect of growth hormone and insulin upon MLC responses and the generation of cytotoxic lymphocytes.

Snow, E. C., Feldbush, T. L., & Oaks, J. A. (1981) · The Journal of Immunology · doi:10.4049/jimmunol.126.1.161 · Cited by 102 · see citing works

Structure and Function of Human Growth Hormone: Implications for the Hematopoietins

Wells, J. A., & de Vos, A. M. (1993) · Annual Review of Biophysics and Biomolecular Structure · doi:10.1146/annurev.bb.22.060193.001553 · Cited by 102 · see citing works

Immunoreactive growth hormone (GH) secretion by human lymphocytes: Augmented release by exogenous GH

Hattori, N., Shimatsu, A., Sugita, M., Kumagai, S., & Imura, H. (1990) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(90)92334-v · Cited by 100 · see citing works

Characterization of Immunoreactive Insulin-Like Growth Factor-I from Leukocytes and Its Regulation by Growth Hormone*

Baxter, J. B., Blalock, J. E., & Weigent, D. A. (1991) · Endocrinology · doi:10.1210/endo-129-4-1727 · Cited by 100 · see citing works

Growth hormone promotes human T cell adhesion and migration to both human and murine matrix proteins in vitro and directly promotes xenogeneic engraftment.

Taub, D. D., Tsarfaty, G., Lloyd, A. R., Durum, S. K., Longo, D., & Murphy, W. J. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117320 · Cited by 99 · see citing works

Hypophysectomy Inhibits the Synthesis of Tumor Necrosis Factor α by Rat Macrophages: Partial Restoration by Exogenous Growth Hormone or Interferon γ*

Edwards, C. K., Lorence, R. M., Dunham, D., Arkins, S., Yunger, L. M., Greager, J. A., Walter, R. J., Dantzer, R., & KELLEY, K. W. (1991) · Endocrinology · doi:10.1210/endo-128-2-989 · Cited by 93 · see citing works

Response of Bipotential Human Marrow Stromal Cells to Insulin-Like Growth Factors: Effect on Binding Protein Production, Proliferation, and Commitment to Osteoblasts and Adipocytes1

Thomas, T., Gori, F., Spelsberg, T. C., Khosla, S., Riggs, B. L., & Conover, C. A. (1999) · Endocrinology · doi:10.1210/endo.140.11.7128 · Cited by 83 · see citing works

Human growth hormone but not ovine or bovine growth hormones exhibits galactopoietic prolactin-like activity in organ culture from bovine lactating mammary gland

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Expression of growth hormone receptors in murine lymphoid cells analyzed by flow cytofluorometry.

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Growth hormone secretion by human peripheral blood mononuclear cells detected by an enzyme-linked immunoplaque assay

Varma, S., Sabharwal, P., Sheridan, J. F., & Malarkey, W. B. (1993) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.76.1.8421102 · Cited by 71 · see citing works

Type I and II insulin-like growth factor receptors on human phytohemagglutinin-activated T lymphocytes

Kozak, R. W., Haskell, J. F., Greenstein, L. A., Rechler, M. M., Waldmann, T. A., & Nissley, S. P. (1987) · Cellular Immunology · doi:10.1016/0008-8749(87)90315-7 · Cited by 67 · see citing works

Lymphocyte subset distribution and natural killer activity in growth hormone deficiency before and during short-term treatment with growth hormone releasing hormone

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Recombinant Human Growth Hormone Promotes Hematopoietic Reconstitution after Syngeneic Bone Marrow Transplantation in Mice

Tian, Z., Woody, M. A., Sun, R., Welniak, L. A., Raziuddin, A., Funakoshi, S., Tsarfaty, G., Longo, D. L., & Murphy, W. J. (1998) · Stem Cells · doi:10.1002/stem.160193 · Cited by 66 · see citing works

The Metabolic Clearance, Distribution, and Degradation of Dimeric and Monomeric Growth Hormone (GH): Implications for the Pattern of Circulating GH Forms*

Baumann, G. P., STOLAR, M. W., & Buchanan, T. A. (1986) · Endocrinology · doi:10.1210/endo-119-4-1497 · Cited by 66 · see citing works

Type I insulin-like growth factor receptor expression in different developmental stages of human thymocytes

Kooijman, R., Scholtens, L. E., Rijkers, G. T., & ZEGERS, B. J. M. (1995) · Journal of Endocrinology · doi:10.1677/joe.0.1470203 · Cited by 64 · see citing works

Growth hormone and insulin-like growth factor I induce immunoglobulin (Ig)E and IgG4 production by human B cells.

Kimata, H., & Fujimoto, M. (1994) · The Journal of Experimental Medicine · doi:10.1084/jem.180.2.727 · Cited by 64 · see citing works

Defective B cell development in Snell dwarf (dw/dw) mice can be corrected by thyroxine treatment

Montecino‐Rodriguez, E., Clark, R. T., Johnson, A. H., Collins, L., & Dorshkind, K. A. (1996) · The Journal of Immunology · doi:10.4049/jimmunol.157.8.3334 · Cited by 62 · see citing works

Primary B cell development is impaired in mice with defects of the pituitary/thyroid axis

Montecino‐Rodriguez, E., CLARK, R. G., Powell-Braxton, L., & Dorshkind, K. A. (1997) · The Journal of Immunology · doi:10.4049/jimmunol.159.6.2712 · Cited by 62 · see citing works

Immunoreactive growth hormone-releasing hormone in rat leukocytes

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The macrophage-activating properties of growth hormone

Edwards, C. K., Arkins, S., Yunger, L. M., Blum, A., Dantzer, R., & Kelley, K. W. (1992) · Cellular and Molecular Neurobiology · doi:10.1007/bf00711550 · Cited by 59 · see citing works

The expanding growth hormone/prolactin family

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Differential effect of growth hormone and insulin-like growth factor-I, insulin-like growth factor-II, and insulin on Ig production and growth in human plasma cells

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RECEPTORS FOR THE INSULIN-LIKE GROWTH FACTORS ON HUMAN EKYTHKUUYTES

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Individual and combined effect of granulocyte–macrophage colony‐stimulating factor and prolactin on maturation of dendritic cells from blood monocytes under serum‐free conditions

Matera, L., Galetto, A., Geuna, M., Vekemans, K., Ricotti, E., Contarini, M., Moro, F., & Basso, G. (2000) · Immunology · doi:10.1046/j.1365-2567.2000.00996.x · Cited by 56 · see citing works

Evidence that Human Growth Hormone Is a Potent Lactogen in Primates*

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Immunologic disparity in the hypopituitary dwarf mouse

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Prolactin exerts hematopoietic growth-promoting effects in vivo and partially counteracts myelosuppression by azidothymidine

Woody, M. A., Welniak, L. A., Sun, R., Tian, Z., Henry, M., Richards, S. M., Raziuddin, A., Longo, D. L., & Murphy, W. J. (1999) · Experimental Hematology · doi:10.1016/s0301-472x(99)00019-3 · Cited by 52 · see citing works

Insulin Growth Factor‐I Inhibits Apoptosis in Hematopoietic: Progenitor Cells Implications in Thymic Aginga

Kelley, K. W., Meier, W. A., Minshall, C. T., Schacher, D. H., Liu, Q., VanHoy, R. W., BURGESS, W., & Dantzer, R. (1998) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1998.tb09590.x · Cited by 50 · see citing works

Growth hormone as an immunomodulating therapeutic agent

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Effects of insulin-like growth factors and growth hormone on the in vitro proliferation of T lymphocytes

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T and B lymphocytes in pituitary dwarf Snell-Bagg mice.

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Recombinant human growth hormone promotes human lymphocyte engraftment in immunodeficient mice and results in an increased incidence of human Epstein Barr virus-induced B-cell lymphoma

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Human insulin-like growth factor I exerts hematopoietic growth-promoting effects after in vivo administration.

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Insulin-like growth factor-1 increases the mitogenic response of human peripheral blood lymphocytes to phytohemagglutinin

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Growth Hormone Receptors and Immunocompetent Cellsa

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Immunological competence in Snell‐Bagg pituitary dwarf mice: Response to the contact‐sensitizing agent oxazolone

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The Human Erythrocyte Insulin-Like Growth Factor I Receptor:Characterization and Demonstration of Ligand-Stimulated Autophosphorylation

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Prolactin increases CD4/CD8 cell ratio in thymus-grafted congenitally athymic nude mice.

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Use of Neuroendocrine Hormones to Promote Reconstitution after Bone Marrow Transplantation

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Growth hormone restores glucocorticoid‐induced T cell suppression

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Prolactin increases the susceptibility of primary leukemia cells to NK and LAK effectors

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The pituitary dwarf mouse: a model for study of endocrine immunodeficiency disease.

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Effects of growth hormone and prolactin on testicular macrophages in long-term hypophysectomized rats

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Adjuvant Effect of Human Growth Hormone with an Inactivated Flavivirus Vaccine

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The in vitro proliferation of thymus epithelial cells stimulated with growth hormone and insulin-like growth factor-I.

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Number and Percentage of NK-Cells Are Decreased in Growth Hormone-Deficient Adults

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