The DOI matches its Crossref record; 56 of the 56 references it cites were found in a registry or an index.
Systemic lupus erythematosus in three ethnic groups: III A comparison of characteristics early in the natural history of the LUMINA cohort
Abstract
Aim: To determine and contrast the socioeconomic-demographic and clinical features of patients with recent onset (5 y) systemic lupus erythematosus (SLE) from three ethnic groups, Hispanic, African-American and Caucasian (H, AA, C). Subjects and methods: SLE cases (American College of Rheumatology criteria) (incident (n ‘ 56), prevalent (n ‘ 173)), were enrolled in a longitudinal study at The University of Alabama at Birmingham, The University of Texas-Houston Health Science Center and The University of Texas Medical Branch at Galveston. Socioeconomic-demographic, clinical, immunological, behavioral and psychological data were obtained using validated instruments and standard laboratory techniques, and compared. Results: 70 H, 88 AA and 71 C SLE patients constitutethis cohort. H and AA patients were younger and of lower socioeconomic-demographic status. They also had evidence of more frequent organ system involvement (renal, cardiovascular), more auto-antibodies, more active disease (after adjusting for discrepant socioeconomic-demographic features), lower levels of social support and more abnormal illness-related behaviors (more in H than in AA). H also were more likely to have an abrupt disease onset; C were more likely to be on antimalarials but less likely to be on corticosteroids. H, AA, and C used health care resources comparably. They had similar levels of pain and physical and mental functioning after adjusting for age, disease duration, income, education, social support, illness-related behaviors, and Systemic Lupus Activity Measure or SLAM scores. Conclusions: H and AA patients have more active SLE, at an earlier age of onset, and a less favorable socioeconomic-demographic structure (worse among the H than AA) which predispose them to a less favorable natural history.
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Cites
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Cited by
Understanding the Epidemiology and Progression of Systemic Lupus Erythematosus
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The impact of increased lupus activity on obstetric outcomes
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Metadata
- Authors
- Alarcón, G. S., Friedman, A. W., Straaton, K. V., Moulds, J. M., Lisse, J., Bastian, H. M., McGwin, G., Bartolucci, A. A., Roseman, J. M., & Reveille, J. D.
- Venue
- Lupus
- Publisher
- SAGE Publications
- Published
- 1999-03
- Volume
- 8
- Issue
- 3
- Pages
- 197-209
- ISSN
- 0961-2033 (ISSN-L)
- 1477-0962
- OpenAlex
- W2118914856
- Cited by
- 309
- References
- 56
- FWCI
- 5.58
- Type
- journal article
- Language
- en
- Open access
- closed
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- Alarcón, G. S., Friedman, A. W., Straaton, K. V., Moulds, J. M., Lisse, J., Bastian, H. M., McGwin, G., Bartolucci, A. A., Roseman, J. M., & Reveille, J. D. (1999). Systemic lupus erythematosus in three ethnic groups: III A comparison of characteristics early in the natural history of the LUMINA cohort. Lupus. https://doi.org/10.1191/096120399678847704
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