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Clinical staging in psychiatry: a cross-cutting model of diagnosis with heuristic and practical value
Open accessAbstract
Staging models are used routinely in general medicine for potentially serious or chronic physical disorders such as diabetes, arthritis and cancers, describing the links between biomarkers, clinical phenotypes and disease extension, and promoting a personalised or stratified medicine approach to treatment planning. Clinical staging involves a detailed description of where an individual exists on a continuum of disorder progression from stage 0 (an at-risk or latency stage) through to stage IV (late or end-stage disease). The approach is popular owing to its clinical utility and is increasingly being applied in psychiatry. The concept offers an informed approach to research and the active promotion of indicated prevention and early intervention strategies. We suggest that for young persons with emerging bipolar disorder, such transdiagnostic staging models could provide a framework that better reflects the developmental psychopathology and matches the complex longitudinal inter-relationships between subsyndromal and syndromal mood, psychotic and other disorders.
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“Transdiagnostic approaches have subsequently been endorsed by paradigms that propose dimensional approaches that cut across diagnostic criteria such as the Research Domain Criteria (RDoC) and the clinical staging model of psychiatry (Scott et al., 2013; Cuthbert, 2014).”
From An Emotion Regulation and Impulse Control (ERIC) Intervention for Vulnerable Young People: A Multi-Sectoral Pilot Study (2021) · cites this paper as Scott et al., 2013
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Self-citationCan bipolar disorder be viewed as a multi-system inflammatory disease?
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Self-citationClinical implications of a staging model for bipolar disorders
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Self-citationStaging: a neglected dimension in psychiatric classification
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Self-citationApplying clinical staging to young people who present for mental health care
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Metadata
- Authors
- Scott, J., Leboyer, M., Hickie, I., Berk, M., Kapczinski, F., Frank, E., Kupfer, D., & McGorry, P.
- Affiliations
- Inserm (FR)
- The University of Sydney (AU)
- Barwon Health (AU)
- University of Pittsburgh (US)
- The University of Melbourne (AU)
- Corresponding author
- Scott, Jan
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 2013-04
- Volume
- 202
- Issue
- 4
- Pages
- 243-245
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- OpenAlex
- W2122348552
- Cited by
- 260
- References
- 11
- Citations by year
- 2026: 12 · 2025: 12 · 2024: 17 · 2023: 12 · 2022: 18 · 2021: 21 · 2020: 23 · 2019: 27 · 2018: 21 · 2017: 22 · 2016: 21 · 2015: 21 · 2014: 25 · 2013: 8
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The British Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Deakin Research Online (Deakin University) (submittedVersion)
- Figshare (submittedVersion, cc-by)
- Funders
- Fondation FondaMental
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
- Keywords
- clinical staging, developmental psychopathology, psychosis, early intervention, prevention, stratified medicine
- MeSH terms
- Bipolar Disorder, Humans, Disease Progression
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