Clinical staging in psychiatry: a cross-cutting model of diagnosis with heuristic and practical value

Research domain criteria (RDoC): toward a new classification framework for research on mental disorders

Insel, T., Cuthbert, B., Garvey, M., Heinssen, R., Pine, D. S., Quinn, K., Sanislow, C., & Wang, P. (2010) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2010.09091379 · Cited by 7,067

Pathways underlying neuroprogression in bipolar disorder: Focus on inflammation, oxidative stress and neurotrophic factors

Berk, M., Kapczinski, F., Andreazza, A. C., Dean, O. M., Giorlando, F., Maes, M., Yücel, M., Gama, C. S., Dodd, S., Dean, B., et al. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.10.001 · Cited by 1,178

Clinical Staging of Psychiatric Disorders: A Heuristic Framework for Choosing Earlier, Safer and more Effective Interventions

McGorry, P. D., Hickie, I. B., Yung, A. R., Pantelis, C., & Jackson, H. J. (2006) · Australian & New Zealand Journal of Psychiatry · doi:10.1080/j.1440-1614.2006.01860.x · Cited by 919

Cognitive–behavioural therapy for severe and recurrent bipolar disorders: Randomised controlled trial

Scott, J., Paykel, E., Morriss, R., Bentall, R., Kinderman, P., Johnson, T., Abbott, R., & Hayhurst, H. (2006) · British Journal of Psychiatry · doi:10.1192/bjp.188.4.313 · Cited by 566

Can bipolar disorder be viewed as a multi-system inflammatory disease?

Leboyer, M., Soreca, I., Scott, J., Frye, M., Henry, C., Tamouza, R., & Kupfer, D. J. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.12.049 · Cited by 417

Clinical implications of a staging model for bipolar disorders

Kapczinski, F. P., Dias, V. V., Kauer‐Sant’Anna, M., Frey, B. N., Grassi‐Oliveira, R., Colom, F., & Berk, M. (2009) · Expert Review of Neurotherapeutics · doi:10.1586/ern.09.31 · Cited by 274

Staging: a neglected dimension in psychiatric classification

Fava, G. A., & Kellner, R. (1993) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1993.tb03362.x · Cited by 252

Setting the stage: from prodrome to treatment resistance in bipolar disorder

Berk, M., Conus, P., Lucas, N., Hallam, K. T., Malhi, G. S., Dodd, S., Yatham, L. N., Yung, A. R., & McGorry, P. D. (2007) · Bipolar Disorders · doi:10.1111/j.1399-5618.2007.00484.x · Cited by 239

Applying clinical staging to young people who present for mental health care

Hickie, I. B., Scott, E. M., Hermens, D. F., Naismith, S. L., Guastella, A. J., Kaur, M., Sidis, A., Whitwell, B., Glozier, N., Davenport, T., et al. (2013) · Early Intervention in Psychiatry · doi:10.1111/j.1751-7893.2012.00366.x · Cited by 229

Frontal lobe changes occur early in the course of affective disorders in young people

Lagopoulos, J., Hermens, D. F., Naismith, S. L., Scott, E. M., & Hickie, I. B. (2012) · BMC Psychiatry · doi:10.1186/1471-244x-12-4 · Cited by 51

Variability in Clinical Outcomes for Youths Treated for Subthreshold Severe Mental Disorders at an Early Intervention Service

Cross, S. P. M., Scott, J. L., Hermens, D. F., & Hickie, I. B. (2018) · Psychiatric Services · doi:10.1176/appi.ps.201700046 · Cited by 26

Stage models for major depression: Cognitive behavior therapy, mechanistic treatment targets, and the prevention of stage transition

Otto, M. W., Birk, J. L., Fitzgerald, H. E., Chauvin, G. V., Gold, A. K., & Carl, J. R. (2022) · Clinical Psychology Review · doi:10.1016/j.cpr.2022.102172 · Cited by 28

Predictors of the Onset of Manic Symptoms and a (Hypo)Manic Episode in Patients with Major Depressive Disorder

Boschloo, L., Spijker, A. T., Hoencamp, E., Kupka, R., Nolen, W. A., Schoevers, R. A., & Penninx, B. W. J. H. (2014) · PLoS ONE · doi:10.1371/journal.pone.0106871 · Cited by 25

Functional deterioration from the premorbid period to 2 years after the first episode of psychosis in early-onset psychosis

Del Rey-Mejías, Á., Fraguas, D., Díaz-Caneja, C. M., Pina-Camacho, L., Castro-Fornieles, J., Baeza, I., Espliego, A., Merchán-Naranjo, J., González-Pinto, A., de la Serna, E., et al. (2015) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-015-0693-5 · Cited by 24

From Perception to Thought: A Phenomenological Approach to Hallucinatory Experience

Raballo, A. (2016) · Schizophrenia Bulletin · doi:10.1093/schbul/sbw144 · Cited by 24

Longitudinal changes in the antecedent and early manifest course of bipolar disorder—A narrative review of prospective studies

Pfennig, A., Leopold, K., Ritter, P. S., Böhme, A., Severus, E., & Bauer, M. (2017) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867417700730 · Cited by 28

Emerging drugs to treat obsessive–compulsive disorder

Pallanti, S., Grassi, G., & Cantisani, A. (2013) · Expert Opinion on Emerging Drugs · doi:10.1517/14728214.2014.875157 · Cited by 23

Self-Reported Long-Term Benefits of Mindfulness-Based Cognitive Therapy in Patients with Bipolar Disorder

Weber, B., Sala, L., Gex-fabry, M., Docteur, A., Gorwood, P., Cordera, P., Bondolfi, G., Jermann, F., Aubry, J., & Mirabel-Sarron, C. (2017) · Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2016.0427 · Cited by 21

A clinical staging approach to improving diagnostics in anxiety disorders: Is it the way to go?

Bokma, W. A., Batelaan, N. M., Hoogendoorn, A. W., Penninx, B. W. J. H., & van Balkom, A. J. L. M. (2019) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867419887804 · Cited by 26

Expanding the search for emerging mental ill health to safeguard student potential and vocational success in high school: A narrative review

Bowman, S., McKinstry, C., Howie, L., & McGorry, P. D. (2020) · Early Intervention in Psychiatry · doi:10.1111/eip.12928 · Cited by 25

Prédire le trouble bipolaire : que pouvons-nous apprendre des études prospectives de cohortes ?

Geoffroy, P. A., Leboyer, M., & Scott, J. L. (2013) · L Encéphale · doi:10.1016/j.encep.2013.05.004 · Cited by 25

Exploring Patterns of Service Utilization Within Children’s Mental Health Agencies

Reid, G. J., Stewart, S. L., Barwick, M. A., Cunningham, C. E., Carter, J., Evans, B., Leschied, A. W., Neufeld, R. W. J., Pierre, J. S., Tobon, J. I., et al. (2020) · Journal of Child and Family Studies · doi:10.1007/s10826-020-01859-2 · Cited by 22

Early stages of bipolar disorder: characterization and strategies for early intervention

Rios, A. C., Noto, M. N., Rizzo, L. B., Mansur, R. B., Martins-Junior, F. E., Grassi‐Oliveira, R., Correll, C. U., & Brietzke, E. M. (2015) · Brazilian Journal of Psychiatry · doi:10.1590/1516-4446-2014-1620 · Cited by 24

A clinical staging model of psychotic disorders based on a long-term follow-up of first-admission psychosis: A validation study

Peralta, V., de Jalón, E. G., Moreno-Izco, L., Peralta, D., Janda, L., Sánchez-Torres, A. M., Cuesta, M. J., Ballesteros, A., Fañanás, L., Gil‐Berrozpe, G. J., et al. (2023) · Psychiatry Research · doi:10.1016/j.psychres.2023.115109 · Cited by 22

A Public Health Perspective on Screening for Psychosis Within General Practice Clinics

Kennedy, L., Johnson, K. A., Cheng, J. M., & Woodberry, K. A. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.01025 · Cited by 20

Integrity of the uncinate fasciculus is associated with the onset of bipolar disorder: a 6-year followed-up study

Li, X., Lu, W., Zhang, R., Zou, W., Gao, Y., Chen, K., Yau, S., Shao, R., McIntyre, R. S., Xu, G., et al. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01222-z · Cited by 19

Current Evidence and Theories in Understanding the Relationship between Cognition and Depression in Childhood and Adolescence: A Narrative Review

Barlati, S., Lisoni, J., Nibbio, G., Baldacci, G., Cicale, A., Ferrarin, L. C., Italia, M., Zucchetti, A., Deste, G., & Vita, A. (2022) · Diagnostics · doi:10.3390/diagnostics12102525 · Cited by 23

The Kraepelinian Dichotomy Viewed by Neuroimaging

d’Albis, M.-A., & Houenou, J. (2014) · Schizophrenia Bulletin · doi:10.1093/schbul/sbu174 · Cited by 20

Clinical staging for youth at‐risk for serious mental illness: A longitudinal perspective

Addington, J., Liu, L., Farris, M. S., Goldstein, B. I., Wang, J., Kennedy, S. H., Bray, S., Lebel, C. A., & MacQUEEN, G. M. (2020) · Early Intervention in Psychiatry · doi:10.1111/eip.13062 · Cited by 20

Validation and refinement of the clinical staging model in a French cohort of outpatient with schizophrenia (FACE-SZ)

Godin, O., Fond, G. B., Bulzacka, E., Schürhoff, F., Boyer, L., André, M., Andrianarisoa, M., Aouizerate, B., Berna, F. S., Capdevielle, D., et al. (2019) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2019.01.003 · Cited by 19

An Emotion Regulation and Impulse Control (ERIC) Intervention for Vulnerable Young People: A Multi-Sectoral Pilot Study

Hall, K., Youssef, G., Simpson, A., Sloan, E., Graeme, L., Perry, N., Moulding, R., Baker, A. L., Beck, A. K., & Staiger, P. K. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.554100 · Cited by 17

Clinical and psychopathological correlates of duration of untreated illness (DUI) in affective spectrum disorders

Menculini, G., Verdolini, N., Gobbicchi, C., Bello, V. D., Serra, R., Brustenghi, F., Armanni, M., Spollon, G., Cirimbilli, F., Brufani, F., et al. (2022) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2022.06.004 · Cited by 19

Empirically driven transdiagnostic stages in the development of mood, anxiety and psychotic symptoms in a cohort of youth followed from birth

Ratheesh, A., Hammond, D., Gao, C. X., Marwaha, S., Thompson, A. D., Hartmann, J., Davey, C. G., Zammit, S., Berk, M., McGorry, P. D., et al. (2023) · Translational Psychiatry · doi:10.1038/s41398-023-02396-4 · Cited by 21

Estadificación clínica en los trastornos mentales graves: trastorno bipolar, depresión y esquizofrenia

de la Fuente-Tomás, L., Sánchez-Autet, M., García-Álvarez, L., González-Blanco, L., Velasco, Á., Sáiz, P. A., García‐Portilla, M. P., & Bobes, J. (2018) · Revista de Psiquiatría y Salud Mental · doi:10.1016/j.rpsm.2018.08.002 · Cited by 23

Is Addiction Really a Chronic Relapsing Disorder?

MacKillop, J. M. (2019) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.14246 · Cited by 20

Is it possible to stage schizophrenia? A systematic review

Martínez-Cao, C., de la Fuente-Tomás, L., García-Fernández, A., González-Blanco, L., Sáiz, P. A., García‐Portilla, M. P., & Bobes, J. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-01889-y · Cited by 19

Heterogeneity of quality of life in young people attending primary mental health services

Cotton, S., Hamilton, M. P., Filia, K., Menssink, J. M., Engel, L., Mihalopoulos, C., Rickwood, D., Hetrick, S. E., Parker, A. G., Herrman, H., et al. (2022) · Epidemiology and Psychiatric Sciences · doi:10.1017/s2045796022000427 · Cited by 16

Insulin resistance in bipolar disorder: relevance to routine clinical care

Calkin, C., & Alda, M. (2015) · Bipolar Disorders · doi:10.1111/bdi.12330 · Cited by 17

Obesity and frontal‐striatal brain structures in offspring of individuals with bipolar disorder: Results from the global mood and brain science initiative

Mansur, R. B., McIntyre, R. S., Cao, B., Lee, Y. L., Japiassú, L., Chen, K., Lu, R., Lu, W., Chen, X., Li, T., et al. (2017) · Bipolar Disorders · doi:10.1111/bdi.12559 · Cited by 16

The course of neuropsychological functioning in young people with attenuated vs discrete mental disorders

Tickell, A. M., Lee, R. S. C., Hickie, I. B., & Hermens, D. F. (2017) · Early Intervention in Psychiatry · doi:10.1111/eip.12499 · Cited by 16

Predictive protein markers for depression severity in mood disorders: A preliminary trans-diagnostic approach study

Lee, H., Rhee, S. J., Kim, J., Lee, Y., Kim, H.-Y., Lee, J., Lee, K., Shin, H., Kim, H., Lee, T. Y., et al. (2021) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2021.07.041 · Cited by 16

Should we intervene at stage 0? A qualitative study of attitudes of asymptomatic youth at increased risk of developing bipolar disorders and parents with established disease

Davison, J., & Scott, J. L. (2017) · Early Intervention in Psychiatry · doi:10.1111/eip.12421 · Cited by 16

Neuroprogression and staging in psychiatry: historical considerations

Kapczinski, F. P., & Streb, L. G. (2014) · Brazilian Journal of Psychiatry · doi:10.1590/1516-4446-2014-3605 · Cited by 16

Early intervention services for non-psychotic mental health disorders: a scoping review protocol

Richards, K. L., Austin, A., Allen, K. L., & Schmidt, U. H. (2019) · BMJ Open · doi:10.1136/bmjopen-2019-033656 · Cited by 15

The progress in the field of clinical staging for mental disorders within the last decade: an updated systematic review

Clarke, S. L., Soons, N., Videler, A. C., van Alphen, S. P. J., Van, H. L., Dil, L., Pappijn, L., Corbeij, S., Broekhof, B., Chanen, A. M., et al. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1473051 · Cited by 20

Neurobiology Youth Follow-up Study: protocol to establish a longitudinal and prospective research database using multimodal assessments for current and past mental health treatment-seeking young people within an early intervention service

Nichles, A., Zmicerevska, N., Song, Y. J. C., Wilson, C. E., McHugh, C. M., Hamilton, B. A., Crouse, J. J., Rohleder, C., Carpenter, J. S., Ho, N., et al. (2021) · BMJ Open · doi:10.1136/bmjopen-2020-044731 · Cited by 11

Transdiagnostic Clinical Staging for Childhood Mental Health: An Adjunctive Tool for Classifying Internalizing and Externalizing Syndromes that Emerge in Children Aged 5–11 Years

Sawrikar, V., MacBeth, A. M., Gillespie‐Smith, K., Brown, M., Lopez-Williams, A., Boulton, K., Guestella, A., & Hickie, I. B. (2022) · Clinical Child and Family Psychology Review · doi:10.1007/s10567-022-00399-z · Cited by 15

Staging model raises fundamental questions about the nature of bipolar disorder

Alda, M., & Kapczinski, F. (2016) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.160151 · Cited by 13

The diagnostic process from primary care to child and adolescent mental healthcare services: the incremental value of information conveyed through referral letters, screening questionnaires and structured multi-informant assessment

Aydın, S., Siebelink, B. M., Crone, M. R., van Ginkel, J. R., Numans, M. E., Vermeiren, R. R. J. M., & Westenberg, P. M. (2022) · BJPsych Open · doi:10.1192/bjo.2022.47 · Cited by 15

The evaluation of a stepped care approach for early intervention of borderline personality disorder

Cavelti, M., Blaha, Y., Lerch, S., Hertel, C., Berger, T., Reichl, C., Koenig, J., & Kaess, M. (2024) · Borderline Personality Disorder and Emotion Dysregulation · doi:10.1186/s40479-024-00256-1 · Cited by 14

Can youth at high risk of illness progression be identified by measures of rumination and sleep‐wake disturbance

Grierson, A. B., Scott, J. L., Glozier, N., Hickie, I. B., Amminger, G. P., Killackey, E. J., McGorry, P. D., Pantelis, C., Phillips, L., Scott, E. M., et al. (2018) · Early Intervention in Psychiatry · doi:10.1111/eip.12757 · Cited by 13

Mapping Psychosis Risk States Onto the Hierarchical Taxonomy of Psychopathology Using Hierarchical Symptom Dimensions

Cowan, H. R., Williams, T. F., Schiffman, J. E., Ellman, L. M., & Mittal, V. A. (2023) · Clinical Psychological Science · doi:10.1177/21677026221146178 · Cited by 14

Clinical staging in severe mental disorders: Bipolar disorder, depression and schizophrenia

de la Fuente-Tomás, L., Sánchez-Autet, M., García-Álvarez, L., González-Blanco, L., Velasco, Á., Martínez, P. A. S., García‐Portilla, M. P., & Bobes, J. (2019) · Revista de Psiquiatría y Salud Mental (English Edition) · doi:10.1016/j.rpsmen.2018.08.002 · Cited by 14

Association between childhood dimensions of attention deficit hyperactivity disorder and adulthood clinical severity of bipolar disorders

Étain, B., Lajnef, M., Loftus, J., Henry, C., Raust, A., Gard, S., Kahn, J., Leboyer, M., Scott, J. L., & Bellivier, F. (2016) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867416642021 · Cited by 13

Risk syndromes in psychiatry: a state-of-the-art overview

Raballo, A., Mechelli, A., Menculini, G., & Tortorella, A. A. V. (2019) · Archives of Psychiatry and Psychotherapy · doi:10.12740/app/109506 · Cited by 12

Functioning in early and late stages of schizophrenia

Costa, L. G., Massuda, R., Pedrini, M., Passos, I. C., Czepielewski, L. S., Brietzke, E. M., & Gama, C. S. (2014) · Trends in Psychiatry and Psychotherapy · doi:10.1590/2237-6089-2014-0028 · Cited by 12

The Staging of Major Mood Disorders: Clinical and Neurobiological Correlates

Muneer, A., & Mazommil, R. (2018) · Psychiatry Investigation · doi:10.30773/pi.2018.05.26 · Cited by 10

Baseline data of a sequential multiple assignment randomized trial (STEP study)

Hartmann, J., Nelson, B., Amminger, G. P., Spark, J., Yuen, H. P., Kerr, M., Polari, A. R., Wallis, N., Blasioli, J., Dixon, L. B., et al. (2022) · Early Intervention in Psychiatry · doi:10.1111/eip.13263 · Cited by 10

Clinical Staging and Its Potential to Enhance Mental Health Care

Mei, C., McGorry, P. D., & Hickie, I. B. (2019) · Cambridge University Press eBooks · doi:10.1017/9781139839518.002 · Cited by 10

Development of an early intervention programme for adolescents with emotion dysregulation and their families: Actions for the treatment of adolescent personality (ATraPA)

Mayoral, M., Valencia‐Agudo, F., Calvo, A., Roldán, L., Espliego, A., Rodríguez-Toscano, E., Kehrmann, L., Arango, C., & Delgado, C. F. (2020) · Early Intervention in Psychiatry · doi:10.1111/eip.12934 · Cited by 10

White matter microstructure in youth at risk for serious mental illness: A comparative analysis

Shakeel, M. K., Hassel, S., Davis, A. D., Metzak, P. D., MacQUEEN, G. M., Arnott, S. R., Bray, S., Frey, B. N., Goldstein, B. I., Hall, G. B., et al. (2021) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2021.111289 · Cited by 10

EMPOWERED trial: protocol for a randomised control trial of digitally supported, highly personalised and measurement-based care to improve functional outcomes in young people with mood disorders

Hickie, I. B., Iorfino, F., Rohleder, C., Song, Y. J. C., Nichles, A., Zmicerevska, N., Capon, W., Guastella, A. J., Leweke, F. M., Scott, J. L., et al. (2023) · BMJ Open · doi:10.1136/bmjopen-2023-072082 · Cited by 9

What can we learn from offspring studies in bipolar disorder?

Loftus, J., Étain, B., & Scott, J. L. (2016) · BJPsych Advances · doi:10.1192/apt.bp.114.013086 · Cited by 9

White Matter Connectivity in Youth at Risk for Serious Mental Illness: A Longitudinal Analysis

Shakeel, M. K., MacQUEEN, G. M., Addington, J., Metzak, P. D., Georgopoulos, G., Bray, S., Goldstein, B. I., MacIntosh, B. J., Wang, J., Kennedy, S. H., et al. (2020) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2020.111106 · Cited by 9

Interventions for Youth at Risk of Bipolar Disorder

Duffy, A. C. (2014) · Current Treatment Options in Psychiatry · doi:10.1007/s40501-013-0006-x · Cited by 9

Advances and challenges in early intervention in psychosis

MALLA, A. K., Shah, J. L., & Lal, S. (2017) · World Psychiatry · doi:10.1002/wps.20453 · Cited by 10

Concepts and misconceptions regarding clinical staging models

Shah, J. L., & Scott, J. L. (2016) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.160196 · Cited by 9

Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disordersPreprint

Byrne, E. M., Zhu, Z., Qi, T., Skene, N., Bryois, J., Pardiñas, A. F., Stahl, E. A., Smoller, J. W., Rietschel, M., Owen, M. J., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/592899 · Cited by 9

Brain connectomes in youth at risk for serious mental illness: an exploratory analysis

Metzak, P. D., Shakeel, M. K., Long, X., Lasby, M., de Souza, R. M., Bray, S., Goldstein, B. I., MacQUEEN, G. M., Wang, J., Kennedy, S. H., et al. (2022) · BMC Psychiatry · doi:10.1186/s12888-022-04118-4 · Cited by 7

Plastic Adaptation to Pathology in Psychiatry: Are Patients with Psychiatric Disorders Pathological Experts?

Amad, A., Expert, P., Lord, L.-D., Fovet, T., & Geoffroy, P. A. (2019) · The Neuroscientist · doi:10.1177/1073858419867083 · Cited by 7

Illness Phase as a Key Assessment and Intervention Window for Psychosis

Kohler, C. G., Wolf, D. H., Abi‐Dargham, A., Anticevic, A., Cho, Y., Fonteneau, C., Gil, R. B., Girgis, R. R., Gray, D. L., Grinband, J., et al. (2022) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2022.05.009 · Cited by 8

Youth Perspectives on ‘Highly Personalised and Measurement‐Based Care’: Qualitative Co‐Design of Education Materials

McKenna, S., Hutcheon, A., Gorban, C., Song, Y. J. C., Scott, E. M., & Hickie, I. B. (2024) · Health Expectations · doi:10.1111/hex.14137 · Cited by 7

Does stage of illness influence recovery-focused outcomes after psychological treatment in bipolar disorder? A systematic review protocol

Tremain, H., Fletcher, K., Scott, J. L., McEnery, C., Berk, M., & Murray, G. (2019) · Systematic Reviews · doi:10.1186/s13643-019-1042-4 · Cited by 9

Is there an association between cardiorespiratory fitness and stage of illness in psychotic disorders? A systematic review and meta‐analysis

Heggelund, J., Vancampfort, D., Tacchi, M. J., Morken, G., & Scott, J. L. (2019) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.13119 · Cited by 7

Self-Reported Cognitive Functions Predict the Trajectory of Paranoid Ideation Over a 15-Year Prospective Follow-Up

Saarinen, A. I. L., Granö, N., & Lehtimäki, T. J. (2020) · Cognitive Therapy and Research · doi:10.1007/s10608-020-10142-z · Cited by 7

Advancements in the molecular understanding of major depressive disorder uncovering novel targets with therapeutic promise: focus on recurrence of illness

Maes, M. H. J., Almulla, A. F., Stoyanov, D., & Zhang, Y. (2025) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2025.2608029 · Cited by 8

Symptom dimensions stability over time in recent onset psychosis: A prospective study

Golay, P., Ramain, J., Empson, L. A., Mebdouhi, N., Elowe, J., Solida, A., & Conus, P. (2022) · Schizophrenia Research · doi:10.1016/j.schres.2022.06.019 · Cited by 6

Risk tolerance in youth with emerging mood disorders

Weinrabe, A., Tran, J., & Hickie, I. B. (2023) · Humanities and Social Sciences Communications · doi:10.1057/s41599-023-02347-w · Cited by 7

Multivariable prediction of functional outcome after first-episode psychosis: a crossover validation approach in EUFEST and PSYSCAN

Slot, M. I. E., Urquijo-Castro, M. F., Rossum, I. W.-V., van Hell, H. H., Dwyer, D., Dazzan, P., Maat, A., de Haan, L., Crespo‐Facorro, B., Glenthoj, B. Y., et al. (2024) · Schizophrenia · doi:10.1038/s41537-024-00505-w · Cited by 5

Intervention précoce pour les premiers épisodes psychotiques d’hier à demain : comment relever les défis liés à son déploiement pour en maximiser les bénéfices ?

MALLA, A. K., Roy, M., Abdel‐Baki, A., Conus, P., & McGorry, P. D. (2021) · Santé mentale au Québec · doi:10.7202/1088190ar · Cited by 6

Applying a clinical staging model in patients affected by schizophrenia spectrum disorder

de Filippis, R., Carbone, E. A., Rania, M., Aloi, M., Segura‐Garcìa, C., & Fazio, P. D. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1387913 · Cited by 6

Pre-onset risk characteristics for mania among young people at clinical high risk for psychosis

Ratheesh, A., Cotton, S., Davey, C. G., Lin, A. P., Wood, S. J., Yuen, H. P., Bechdolf, A., McGorry, P. D., Yung, A. R., Berk, M., et al. (2017) · Schizophrenia Research · doi:10.1016/j.schres.2017.04.036 · Cited by 6

A comparison of three methods in categorizing functional status to predict hospital readmission across post-acute care

Li, C., Karmarkar, A. M., Kuo, Y., Mehta, H. B., Mallinson, T., Haas, A. M., Kumar, A., & Ottenbacher, K. J. (2020) · PLoS ONE · doi:10.1371/journal.pone.0232017 · Cited by 6

L’imagerie cérébrale en psychiatrie clinique : du diagnostic différentiel au machine learning

Amad, A., Cancel, A., & Fovet, T. (2016) · Cairn.info · doi:10.1684/ipe.2016.1475 · Cited by 6

Zooming into the micro-level of experience : an approach for understanding and treating psychopathology

Kramer, I. M. A. (2015) · Research Publications (Maastricht University) · doi:10.26481/dis.20150430ik · Cited by 6

Tijdig herkennen en behandelen van borderlineproblematiek bij jongeren met MBT-early

Hutsebaut, J., Feenstra, D., Keur, E., Schäfer, B., & Bales, D. (2017) · Tijdschrift voor Psychotherapie · doi:10.1007/s12485-017-0216-6 · Cited by 5

Effect of an online healthy lifestyle psychoeducation programme to improve cardiometabolic outcomes and affective symptoms in youth receiving mental health care: study protocol for a pilot clinical trial.

Wilson, C. E., Nichles, A., Zmicerevska, N., Carpenter, J. S., Song, Y. J. C., McHugh, C. M., Hamilton, B. A., Hockey, S. J., Scott, E. M., & Hickie, I. B. (2021) · BMJ Open · doi:10.1136/bmjopen-2020-044977 · Cited by 5

Integrity of cerebellar tracts associated with the risk of bipolar disorder

Hou, L., Lam, B. Y., Wong, N. M. L., Lu, W., Zhang, R., Ning, Y., & Lin, K. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-02097-4 · Cited by 5

Le modèle du staging (ou des stades évolutifs) appliqué aux troubles bipolaires

Scott, J. L., & Henry, C. (2018) · L Encéphale · doi:10.1016/s0013-7006(19)30076-4 · Cited by 5

Effects of adjunctive brexpiprazole on sleep-wake and circadian parameters in youth with depressive disorders: study protocol for a clinical trial

Carpenter, J. S., Zmicerevska, N., Crouse, J. J., Nichles, A., Garland, A., Song, Y. J. C., Wilson, C. E., Rohleder, C., McHugh, C. M., Leweke, F. M., et al. (2022) · BMJ Open · doi:10.1136/bmjopen-2021-056298 · Cited by 5

Intervening early in bipolar disorder in young people: a review of the clinical staging model

Power, P. (2015) · Irish Journal of Psychological Medicine · doi:10.1017/ipm.2014.72 · Cited by 4

Economic rationality in youth with emerging mood disorders.

Weinrabe, A., Chung, H.-K., Tymula, A. A., Tran, J., & Hickie, I. B. (2020) · Journal of Neuroscience Psychology and Economics · doi:10.1037/npe0000129 · Cited by 4

Functional imaging in youth at risk for transdiagnostic serious mental illness: Initial results from the PROCAN study

Metzak, P. D., Addington, J., Hassel, S., Goldstein, B. I., MacIntosh, B. J., Lebel, C. A., Wang, J., Kennedy, S. H., MacQUEEN, G. M., & Bray, S. (2020) · Early Intervention in Psychiatry · doi:10.1111/eip.13078 · Cited by 4

Double-blind, randomised placebo-controlled clinical trial of metformin as an adjunct to a sleep–wake, activity and metabolically focused behavioural intervention to improve cardiometabolic outcomes and mood symptoms in youth with major mood syndromes: study protocol

Wilson, C. E., Carpenter, J. S., Nichles, A., Zmicerevska, N., Song, Y. J. C., McHugh, C. M., Hamilton, B. A., Hockey, S. J., Crouse, J. J., Koethe, D., et al. (2023) · BMJ Open · doi:10.1136/bmjopen-2022-064682 · Cited by 4

Impaired causal awareness and associated cortical–basal ganglia structural changes in youth psychiatric disorders

Griffiths, K. R., Lagopoulos, J., Hermens, D. F., Lee, R. S. C., Guastella, A. J., Hickie, I. B., & Balleine, B. W. (2016) · NeuroImage Clinical · doi:10.1016/j.nicl.2016.06.017 · Cited by 4

Challenges and options for estimating the prevalence of schizophrenia, psychotic disorders, and bipolar disorders in population surveys

McGrath, J. J., Charlson, F., & Whiteford, H. (2016) · Cited by 4

Understanding Eating Disorders Across Samples and Stages

Allen, K. L. (2019) · Journal of Adolescent Health · doi:10.1016/j.jadohealth.2018.11.005 · Cited by 4

Development of a Novel Staging Model for Affective Disorders Using Partial Least Squares Bootstrapping: Effects of Lipid-Associated Antioxidant Defenses and Neuro-Oxidative StressPreprint

Maes, M. H. J., Moraes, J. B., Congio, A. C., Bonifácio, K. L., Barbosa, D. S., Vargas, H. O., Michelin, A. P., Carvalho, A. F., & Nunes, S. O. V. (2018) · Preprints.org · doi:10.20944/preprints201812.0092.v1 · Cited by 4

ACNP 56th Annual Meeting: Panels, Mini-Panels and Study Groups, December 4 – 7, 2017

pregnancy, T. H. P. I. A. S. O. I. B. S. I. E. B. T. T. W. O., & individual., M. Q. S. T. I. C. S. T. D. A. G. O. T. E. Y. T. P. L. A. M. N. M. A. B. I. S. T. S. S. O. A. A. A. E. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2017.263 · Cited by 4

PsiOvi Staging Model for Schizophrenia (PsiOvi SMS): A New Internet Tool for Staging Patients with Schizophrenia

Martínez-Cao, C., Lasheras, F. S., García-Fernández, A., González-Blanco, L., Madera, P. Z., Sáiz, P. A., Bobes, J., & García‐Portilla, M. P. (2024) · European Psychiatry · doi:10.1192/j.eurpsy.2024.17 · Cited by 3

Effects of three prophylactic interventions on French middle-schoolers’ mental health: protocol for a randomized controlled trial

Vaillant-Coindard, E., Briet, G., Lespiau, F., Gisclard, B., & Charbonnier, É. (2024) · BMC Psychology · doi:10.1186/s40359-024-01723-8 · Cited by 4

Clinical Staging for Personality Disorders in Older Adults

Conjaerts, J. A. P., Videler, A. C., Schepman, R., Elfeddali, I., Rosowsky, E., & van Alphen, S. P. J. (2024) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/08919887241254467 · Cited by 6

Early Identification of Psychiatric Disorders

Lee, T. Y., Kim, M., & Kwon, J. S. (2019) · Advances in experimental medicine and biology · doi:10.1007/978-981-32-9721-0_18 · Cited by 4

Staging of Bipolar Disorder

Fountoulakis, K. N. (2014) · Springer eBooks · doi:10.1007/978-3-642-37216-2_15 · Cited by 3

The nosology of addiction as a medical condition: a concise history and review of contemporary perspectives

Garber, M. L., & MacKillop, J. (2025) · Neuropsychopharmacology · doi:10.1038/s41386-025-02257-2 · Cited by 3

Transdiagnostic stage-based monitoring of public mental health

Buchweitz, C., Viduani, A. C., Herrman, H., Kohrt, B. A., McGorry, P. D., Salum, G. A., Sartor, C., Saxena, S., & Kieling, C. (2026) · Nature Reviews Psychology · doi:10.1038/s44159-025-00527-w · Cited by 2

Long-term trajectories of clinical staging in first-episode psychosis and their associated cognitive outcome: A 21-year follow-up study

Cuesta, M. J., Sánchez-Torres, A. M., Moreno-Izco, L., de Jalón, E. G., Gil‐Berrozpe, G. J., Peralta, V., Ballesteros, A., Fañanás, L., Janda, L., Papiol, S., et al. (2024) · Revista de Psiquiatría y Salud Mental · doi:10.1016/j.sjpmh.2024.02.001 · Cited by 2

Identifying clinical and proteomic markers for early diagnosis and prognosis prediction of major psychiatric disorders

Lee, H. J., Han, D., Rhee, S. J., Lee, J., Kim, J., Lee, Y., Kim, E. Y., Park, D. Y., Roh, S., Baik, M., et al. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.10.054 · Cited by 4

Clinical sleep staging for insomnia disorder

Gauld, C., & Blanken, T. F. (2024) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2024.11.009 · Cited by 2

Substance use disorders: a call for a staging paradigm

Bachi, K., Hurd, Y. L., & Salsitz, E. A. (2025) · Translational Psychiatry · doi:10.1038/s41398-025-03484-3 · Cited by 2

Clinical staging models: From general medicine to mental disorders

Scott, J. L., & Henry, C. (2017) · BJPsych Advances · doi:10.1192/apt.bp.116.016436 · Cited by 40

[The importance of the staging model in bipolar disorder].

Bélteczki, Z., Kocsis, C., van der Wijk, I., & Rihmer, Z. (2023) · PubMed

Clinical staging: a heuristic model for psychiatry and youth mental health

McGorry, P. D., Purcell, R., Hickie, I. B., Yung, A. R., Pantelis, C., & Jackson, H. J. (2007) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.2007.tb01335.x · Cited by 293

Clinical Staging of Psychiatric Disorders: A Heuristic Framework for Choosing Earlier, Safer and more Effective Interventions

McGorry, P. D., Hickie, I. B., Yung, A. R., Pantelis, C., & Jackson, H. J. (2006) · Australian & New Zealand Journal of Psychiatry · doi:10.1080/j.1440-1614.2006.01860.x · Cited by 919

Staging in bipolar disorder: from theoretical framework to clinical utility

Berk, M., Post, R., Ratheesh, A., Gliddon, E., Singh, A., Vieta, E., Carvalho, A. F., Ashton, M. M., Berk, L., Cotton, S. M., et al. (2017) · World Psychiatry · doi:10.1002/wps.20441 · Cited by 216