Recovery-focused cognitive–behavioural therapy for recent-onset bipolar disorder: Randomised controlled pilot trial
Open accessAbstract
Background: Despite evidence for the effectiveness of structured psychological therapies for bipolar disorder no psychological interventions have been specifically designed to enhance personal recovery for individuals with recent-onset bipolar disorder. Aims: A pilot study to assess the feasibility and effectiveness of a new intervention, recovery-focused cognitive–behavioural therapy (CBT), designed in collaboration with individuals with recent-onset bipolar disorder intended to improve clinical and personal recovery outcomes. Method: A single, blind randomised controlled trial compared treatment as usual (TAU) with recovery-focused CBT plus TAU (n= 67). Results: Recruitment and follow-up rates within 10% of pre-planned targets to 12-month follow-up were achieved. An average of 14.15 h (s.d. = 4.21) of recovery-focused CBT were attended out of a potential maximum of 18 h. Compared with TAU, recovery-focused CBT significantly improved personal recovery up to 12-month follow-up (Bipolar Recovery Questionnaire mean score 310.87, 95% CI 75.00–546.74 (s.e. = 120.34),P= 0.010,d=0.62) and increased time to any mood relapse during up to 15 months follow-up (χ 2= 7.64,P<0.006, estimated hazard ratio (HR) = 0.38, 95% CI 0.18–0.78). Groups did not differ with respect to medication adherence. Conclusions: Recovery-focused CBT seems promising with respect to feasibility and potential clinical effectiveness. Clinical- and cost-effectiveness now need to be reliably estimated in a definitive trial.
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A pilot study of recovery-focused CBT with 33 subjects showed evidence of reduction of relapse in the intervention group.
“A promising new direction in CBT has been established by a pilot study of “recovery‐focused CBT” where 33 subjects received the novel CBT intervention, with evidence of reduction of relapse in the intervention group.90”
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Michalak, E. E., Barnes, S. J., Morton, E. E., O'Brien, H. L., Murray, G., Hole, R., & Meyer, D. (2022) · doi:10.2196/preprints.36213
- Authors
- Jones, S. H., Smith, G., Mulligan, L. D., Lobban, F., Law, H., Dunn, G., Welford, M., Kelly, J., Mulligan, J., & Morrison, A. P.
- Affiliations
- University of Manchester (GB)
- National Health Service (GB)
- ORCID
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 2015-01
- Volume
- 206
- Issue
- 1
- Pages
- 58-66
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- OpenAlex
- W2123064748
- Cited by
- 118
- References
- 42
- Citations by year
- 2026: 4 · 2025: 7 · 2024: 11 · 2023: 8 · 2022: 7 · 2021: 10 · 2020: 9 · 2019: 24 · 2018: 13 · 2017: 8 · 2016: 11 · 2015: 5
- FWCI
- 6.11
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The British Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Research Explorer (The University of Manchester) (publishedVersion)
- Lancaster EPrints (Lancaster University) (acceptedVersion)
- Funders
- University of Pittsburgh
- National Institute for Health and Care Research (RP-PG-0606-1086)
- Programme Grants for Applied Research
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Health Sciences › Health Professions › General Health Professions › Mental Health and Patient Involvement
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Keywords
- bipolar disorder, personal recovery, usual care, medication adherence, feasibility, co-designed intervention, psychological intervention
- MeSH terms
- Adolescent, Adult, Aged, Bipolar Disorder, Female, Humans, Male, Middle Aged, Patient Compliance, Pilot Projects, Professional-Patient Relations, Cognitive Behavioral Therapy, Single-Blind Method, Treatment Outcome, Young Adult, Early Medical Intervention
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