The recovery of factors associated with decision-making capacity in individuals with psychosis
Open accessAbstract
Background: There is limited data on the recovery of factors associated with decisional capacity in patients with psychosis. Aims: To study the relationship between changes in mental capacity, symptoms and global functioning using structured measures during treatment for psychosis. Method: Fifty-six patients with psychosis were assessed for capacity to consent to treatment on admission and at 6 and 12 weeks following treatment. The MacArthur Competence Assessment Tool – Treatment, the Positive and Negative Symptom Scale and the Global Assessment of Functioning Scale were used to measure mental capacities, symptom severity and global functioning respectively. Treating consultants rated capacity to consent, masked to these measures. Results: Greater impairments on all measures were found in patients assessed as lacking capacity. These improved with treatment over 12 weeks with significant effect sizes (0.5 to 0.6). Stronger correlations between mental capacities, positive symptoms (-0.47) and global functioning (0.56) were noted in the first 6 weeks. Conclusions: Impairments in capacity in acute stages of psychosis are related to symptom severity and functional impairment. They improve during treatment, particularly in the first 6 weeks.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Individuals exhibiting more severe symptoms are more likely to be perceived as incapable of understanding and therefore of making decisions.
“Considering that individuals exhibiting more severe symptoms are more likely to be perceived as incapable of understanding and therefore of making decisions [175,176]”
From Factors Associated with Perceived Coercion in Adults Receiving Psychiatric Care: A Scoping Review (2025) · cites this paper as [175]
The Results report that hospitalized patients with psychosis whom clinicians judged to lack capacity had more severe symptoms and lower understanding scores. The Clinical implications section also says clinicians may be influenced by deficits in understanding. The claim extends this finding to individuals generally, whereas the study concerns patients with psychosis and capacity to consent to treatment. (LLM, conf=0.82)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
The Positive and Negative Syndrome Scale (PANSS) for schizophrenia.
Kay, S. R., Fiszbein, A., & Opler, L. A. (1987) · Schizophrenia Bulletin · doi:10.1093/schbul/13.2.261 · Cited by 21,378 · see citing works
Convention on the Rights of Persons with Disabilities
Myhill, W. N. (2014) · Encyclopedia of Human Services and Diversity · doi:10.4135/9781483346663.n124 · Cited by 2,158 · see citing works
Assessment of Patients' Competence to Consent to Treatment
Appelbaum, P. S. (2007) · New England Journal of Medicine · doi:10.1056/nejmcp074045 · Cited by 1,427 · see citing works
Leucht, S., Kane, J., Kissling, W., Hamann, J., Etschel, E., & Engel, R. R. (2005) · Schizophrenia Research · doi:10.1016/j.schres.2005.04.008 · Cited by 1,230 · see citing works
Schizophrenia Is a Cognitive Illness: Time for a Change in Focus
Kahn, R. S., & Keefe, R. S. E. (2013) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2013.155 · Cited by 825 · see citing works
Assessing Competence to Consent to Treatment: A Guide for Physicians and Other Health Prefessionals
Grisso, T., & Appelbaum, P. S. (1998) · doi:10.1093/oso/9780195103724.001.0001 · Cited by 823 · see citing works
Tests of competency to consent to treatment
Roth, L. H., Meisel, A., & Lidz, C. W. (1977) · American Journal of Psychiatry · doi:10.1176/ajp.134.3.279 · Cited by 662 · see citing works
Grisso, T., & Appelbaum, P. S. (1995) · Law and Human Behavior · doi:10.1007/bf01499323 · Cited by 595 · see citing works
Decisional Capacity for Informed Consent in Schizophrenia Research
Carpenter, W. T. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.6.533 · Cited by 506 · see citing works
Assessing Decisional Capacity for Clinical Research or Treatment: A Review of Instruments
Dunn, L. B., Nowrangi, M. A., Palmer, B. W., Jeste, D. V., & Saks, E. R. (2006) · American Journal of Psychiatry · doi:10.1176/ajp.2006.163.8.1323 · Cited by 464 · see citing works
The MacArthur Treatment Competence Study. I: Mental illness and competence to consent to treatment.
Appelbaum, P. S., & Grisso, T. (1995) · Law and Human Behavior · doi:10.1007/bf01499321 · Cited by 424 · see citing works
Grisso, T., Appelbaum, P. S., Mulvey, E. P., & Fletcher, K. E. (1995) · Law and Human Behavior · doi:10.1007/bf01499322 · Cited by 253 · see citing works
Owen, G. S., Richardson, G., David, A. S., Szmukler, G., Hayward, P., & Hotopf, M. (2008) · BMJ · doi:10.1136/bmj.39580.546597.be · Cited by 172 · see citing works
Prevalence and predictors of mental incapacity in psychiatric in-patients
Cairns, R., Maddock, C., Buchanan, A. W., David, A. S., Hayward, P., Richardson, G., SZMUKLER, G. I., & Hotopf, M. H. (2005) · The British Journal of Psychiatry · doi:10.1192/bjp.187.4.379 · Cited by 165 · see citing works
Bipolar disorder: assessment and management.
Parker, G. B. (2007) · PubMed · Cited by 165 · see citing works
Assessing Competence to Consent to Treatment
Hoffman, B. F. (1980) · The Canadian Journal of Psychiatry · doi:10.1177/070674378002500427 · Cited by 165 · see citing works
Competence of mentally ill patients: a comparative empirical study
VOLLMANN, J., BAUER, A., DANKER-HOPFE, H., & HELMCHEN, H. (2003) · Psychological Medicine · doi:10.1017/s0033291703008389 · Cited by 159 · see citing works
Palmer, B. W., Dunn, L. B., Appelbaum, P. S., & Jeste, D. V. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.3.230 · Cited by 141 · see citing works
Herring, J. (2016) · doi:10.1093/acprof:oso/9780198737278.001.0001 · Cited by 124 · see citing works
Moye, J. A., Gurrera, R. J., Karel, M. J., Edelstein, B. A., & O'Connell, C. (2005) · Clinical Psychology Review · doi:10.1016/j.cpr.2005.04.013 · Cited by 103 · see citing works
Competency to decide about treatment or research
Roth, L. H., Lidz, C. W., Meisel, A., Soloff, P. H., Kaufman, K. R., Spiker, D. G., & FOSTER, F. G. (1982) · International Journal of Law and Psychiatry · doi:10.1016/0160-2527(82)90013-9 · Cited by 96 · see citing works
O’Reilly, K., Donohoe, G. J., Coyle, C., O’Sullivan, D., Rowe, A. R., Losty, M., McDonagh, T., McGuinness, L., Ennis, Y., Watts, E., et al. (2015) · BMC Psychiatry · doi:10.1186/s12888-015-0548-0 · Cited by 94 · see citing works
Self-citationPalmer, B. W., & Savla, G. N. (2007) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617707071299 · Cited by 82 · see citing works
Constructing competence: formulating standards of legal competence to make medical decisions.
Berg, J. W., Appelbaum, P. S., & Grisso, T. (1996) · PubMed · Cited by 80 · see citing works
Decisional Capacity to Consent to Research Among Patients With Bipolar Disorder
Palmer, B. W., Dunn, L. B., Depp, C. A., Eyler, L. T., & Jeste, D. V. (2007) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v68n0505 · Cited by 57 · see citing works
Howe, V., Foister, K., Jenkins, K., Skene, L. L. C., Copolov, D., & Keks, N. A. (2005) · Schizophrenia Research · doi:10.1016/j.schres.2005.03.005 · Cited by 55 · see citing works
Functional mental capacity is not independent of the severity of psychosis
Rutledge, E., Kennedy, M., O'Neill, H., & Kennedy, H. G. (2008) · International Journal of Law and Psychiatry · doi:10.1016/j.ijlp.2007.11.002 · Cited by 44 · see citing works
Self-citationO’Reilly, K., O'Connell, P., Donohoe, G. J., Coyle, C., O’Sullivan, D., Azvee, Z., Maddock, C., Sharma, K., Sadi, H., McMahon, M., et al. (2016) · Psychological Medicine · doi:10.1017/s0033291716002154 · Cited by 39 · see citing works
Self-citationMental capacity and consent to treatment in psychiatric patients: the state of the research
Candia, P. C., & Barba, A. C. (2011) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e328349bba5 · Cited by 38 · see citing works
Dornan, J., Kennedy, M., Garland, J., Rutledge, E., & Kennedy, H. G. (2015) · BMC Research Notes · doi:10.1186/s13104-015-1547-4 · Cited by 29 · see citing works
Self-citationThe capacity to refuse psychiatric treatment: A guide to the law for clinicians and tribunal members
Ryan, C. J., Callaghan, S., & Peisah, C. (2015) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867415572007 · Cited by 29 · see citing works
The Course of Neurocognitive Changes in Acute Psychosis: Relation to Symptomatic Improvement
Anda, L. G., Brønnick, K., Johnsen, E., Kroken, R. A., Jørgensen, H. A., & Løberg, E. (2016) · PLoS ONE · doi:10.1371/journal.pone.0167390 · Cited by 20 · see citing works
Flagged first, then by citations
1 of the 33 references couldn’t be matched to a known paper.
Research works printed but not linked: 5
- [11]National Institute for Health and Care Excellence. Psychosis and Schizophrenia in Adults: Prevention and Management. NICE, 2014 (https://www.nice.org.uk/guidance/cg178). 32207892
- [25]Candia PC, Barba AC. Mental capacity and consent to treatment in psychiatric patients. Curr Opin Psychiatry 2011; 24: 442– 6. 21743329
- [28]American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR). APA, 2000.
- [29]National Institute for Health and Care Excellence. Depression in Adults: Recognition and Management (CG90). NICE, 2009 (https://www.nice.org.uk/guidance/cg90). 31990491
- [39]O’Reilly K, Donohoe G, Coyle C, O’Sullivan D, Rowe A, Losty M, et al Prospective cohort study of the relationship between neuro-cognition, social cognition and violence in forensic patients with schizophrenia and schizoaffective disorder. BMC Psychiatry 2015; 10: 155. PMC4496853 26159728
Cited by
Sorted by citations
O’Reilly, K., O’Connell, P., O’Sullivan, D., Corvin, A. P., Sheerin, J., O’Flynn, P., Donohoe, G. J., McCarthy, H., Ambrosh, D., O’Donnell, M., et al. (2019) · BMC Psychiatry · doi:10.1186/s12888-019-2372-4 · Cited by 29 · see citing works
Self-citationCapacity to consent to treatment in psychiatry inpatients - a systematic review
Curley, A., Watson, C., & Kelly, B. D. (2022) · International Journal of Psychiatry in Clinical Practice · doi:10.1080/13651501.2021.2017461 · Cited by 27 · see citing works
Pons, E. V., Salvador‐Carulla, L., Calcedo‐Barba, A., Paz, S., Messer, T., Pacciardi, B., & Zeller, S. L. (2020) · Health Science Reports · doi:10.1002/hsr2.179 · Cited by 23 · see citing works
Kennedy, H. G., Mullaney, R., McKenna, P. F., Thompson, J., Timmons, D., Gill, P., O’Sullivan, O. P., Braham, P., Duffy, D. M., Kearns, A., et al. (2020) · BMC Psychiatry · doi:10.1186/s12888-020-02912-6 · Cited by 20 · see citing works
Self-citationTurner, D. T., MacBeth, A. M., Larkin, A., Moritz, S., Livingstone, K., Campbell, A., & Hutton, P. (2018) · Schizophrenia Bulletin · doi:10.1093/schbul/sby136 · Cited by 14 · see citing works
How to Measure Progress in Forensic Care
Kennedy, H. G., O'Reilly, K., Davoren, M., O'Flynn, P., & O'Sullivan, O. P. (2019) · Long-Term Forensic Psychiatric Care · doi:10.1007/978-3-030-12594-3_8 · Cited by 16 · see citing works
Self-citationFactors Associated with Perceived Coercion in Adults Receiving Psychiatric Care: A Scoping Review
Lessard-Deschênes, C., Pariseau-Legault, P., Billé, V., Sergerie-Richard, S., Hudson, E., Silva, B., Drouin, J.-S., Désilets, M., & Goulet, M.-H. (2025) · Healthcare · doi:10.3390/healthcare13151868 · Cited by 10 · see citing works
Top Ten Tips Palliative Care Clinicians Should Know About Mental Health and Serious Illness
Riordan, P. A., Briscoe, J. G., Kamal, A. H., Jones, C. A., & Webb, J. A. (2018) · Journal of Palliative Medicine · doi:10.1089/jpm.2018.0207 · Cited by 8 · see citing works
Koukopoulos, A. E., Mandarelli, G., Maglio, G., Macellaro, M., Cifrodelli, M., Kotzalidis, G. D., Tarsitani, L., Biondi, M., & Ferracuti, S. (2020) · Journal of Affective Disorders Reports · doi:10.1016/j.jadr.2020.100037 · Cited by 6 · see citing works
Impact of Service Organisation on Teaching and Training
Kennedy, H. G., Castelletti, L., & O’Sullivan, O. P. (2018) · Springer eBooks · doi:10.1007/978-3-319-74664-7_14 · Cited by 6 · see citing works
Self-citationMorena, D., Lippi, M., Fazio, N. D., Delogu, G., Rinaldi, R., Frati, P., & Fineschi, V. (2024) · Medicina · doi:10.3390/medicina60050764 · Cited by 6 · see citing works
Grover, D., Tekkalaki, B. V., Yadawad, V. S., Patil, N. M., Chate, S. S., & Patil, S. (2022) · PubMed Central · doi:10.1177/02537176221100272 · Cited by 4 · see citing works
Mental capacity, insight, and severity of illness in psychiatric in-patients: A prospective study
Aman, N., Pandurangi, S. A., Kulkarni, P. R., & Kulkarni, R. R. (2025) · Indian Journal of Psychiatry · doi:10.4103/indianjpsychiatry.indianjpsychiatry_977_24 · Cited by 2 · see citing works
Involuntary Clozapine Treatment: A Systematic Review
Verdoux, H., Lepetit, A., & Schulte, P. F. J. (2026) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.70076 · Cited by 2 · see citing works
Psychiatric Illness and Medical Decision-Making Capacity: A Retrospective Study in Medical Settings
Sangroula, D., Mainali, P., Hagi, K., & Peteru, S. (2020) · Psychiatry International · doi:10.3390/psychiatryint1020012 · Cited by 2 · see citing works
Villar, K. D. (2020) · Queensland University of Technology · doi:10.5204/thesis.eprints.206025
Kennedy, H. G., Mullaney, R., McKenna, P. F., Thompson, J., Timmons, D., Gill, P., O’Sullivan, O. P., Braham, P., Duffy, D. M., Kearns, A., et al. (2020) · Figshare · doi:10.6084/m9.figshare.13142152
Self-citationConstipation and capacity: The full stop
Judd, S., & Hua-Rupp, K.-L. (2026) · Cambridge University Press eBooks · doi:10.1017/9781009335874.014
Kulkarni, R. R., Pandurangi, S. A., Kulkarni, P. R., & Aman, N. (2026) · Indian Journal of Psychiatry · doi:10.4103/indianjpsychiatry_957_25
- Authors
- Fernandez, C., Kennedy, H. G., & Kennedy, M.
- Affiliations
- St. Patrick's Hospital (IE)
- Trinity College Dublin (IE)
- Corresponding author
- Kennedy, Harry G.
- ORCID
- Kennedy, Harry G.
- Venue
- BJPsych Open
- Publisher
- Royal College of Psychiatrists
- Published
- 2017-05
- Volume
- 3
- Issue
- 3
- Pages
- 113-119
- ISSN
- 2056-4724 (ISSN-L)
- PMC
- PMC5415675
- OpenAlex
- W2610902548
- Cited by
- 19
- References
- 33
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 1 · 2022: 1 · 2021: 1 · 2020: 6 · 2019: 2 · 2018: 3
- FWCI
- 3.73
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- BJPsych Open (publishedVersion)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Healthcare Decision-Making and Restraints
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
- Keywords
- decision-making capacity, psychosis, consent to treatment, treatment recovery, positive symptoms, global functioning, functional disability, acute psychosis, antipsychotic drugs
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review