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Lipoprotein (a) upregulates ABCA1 in liver cells via scavenger receptor-B1 through its oxidized phospholipids
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Several other candidate Lp(a) receptors have been proposed, including other lipoprotein receptors, toll-like receptors, scavenger receptors, lectins, and plasminogen receptors.
“Over time, several other candidate Lp(a) receptors have been proposed, including other lipoprotein receptors49,50, toll-like receptors51, scavenger receptors52,53, lectins26,54, and plasminogen receptors29,33.”
From Functional interrogation of cellular Lp(a) uptake by genome-scale CRISPR screening (2025) · cites this paper as [53]
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The role of oxidized phospholipids in mediating lipoprotein(a) atherogenicity
Tsimikas, S., & Witztum, J. L. (2008) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e328308b622 · Cited by 138
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Cited by
Sorted by citations
Hepatic Lipoprotein Metabolism: Current and Future In Vitro Cell-Based Systems
Kiss, I., Neuwert, N., Oberle, R., Hengstschläger, M., Osmanagic-Myers, S., & Stangl, H. (2025) · Biomolecules · doi:10.3390/biom15070956 · Cited by 11
Functional interrogation of cellular Lp(a) uptake by genome-scale CRISPR screening
Khan, T. G., Bragazzi Cunha, J., Raut, C., Burroughs, M., Vyas, H. S., Leix, K., Goonewardena, S. N., Smrcka, A. V., Speliotes, E. K., & Emmer, B. T. (2025) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2025.119174 · Cited by 6
Metadata
- Authors
- Sharma, M., Von Zychlinski-Kleffmann, A., Porteous, C. M., Jones, G. T., Williams, M. J. A., & McCormick, S. P. A.
- Venue
- Journal of Lipid Research
- Publisher
- Elsevier BV
- Published
- 2015-07
- Volume
- 56
- Issue
- 7
- Pages
- 1318-1328
- ISSN
- 0022-2275
- PMC
- PMC4479336
- Cited by
- 32
- References
- 1
- Language
- en
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