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The ever-expanding role of degradation in the regulation of apolipoprotein B metabolism

Ginsberg, Henry N., Fisher, Edward A.·2009·Journal of Lipid Research
DOI 10.1194/jlr.r800090-jlr200
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  • VLDL/APOB production is regulated mainly via posttranslational control.

    “VLDL/APOB production is regulated mainly via posttranslational control (19).”

    From Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism (2012) · cites this paper as [19]

    The Concluding Remarks (page not specified) say that major regulatory pathways involve degradation of apoB or VLDL rather than changes in apoB synthesis. But the Abstract (page not specified) identifies both cotranslational and posttranslational targeting for degradation, so the source does not establish that control is mainly posttranslational. (LLM, conf=0.84)

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Research works printed but not linked: 46

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Metadata

Authors
Ginsberg, H. N., & Fisher, E. A.
Venue
Journal of Lipid Research
Publisher
Elsevier BV
Published
2009-04
Volume
50
Pages
S162-S166
ISSN
0022-2275
DOI
10.1194/jlr.r800090-jlr200
Cited by
172
References
1
Language
en
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