CoChat
Sign Up
Cited by 112

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Lipid rafts in glial cells: role in neuroinflammation and pain processing

Miller, Yury I., Navia-Pelaez, Juliana M., Corr, Maripat, Yaksh, Tony L.·2020·Journal of Lipid Research
DOI 10.1194/jlr.tr119000468
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1194/jlr.tr119000468

Cites

6 of 6 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Cholesterol loading into glial cells clusters inflammatory proteins and causes inflammation.

    “Cholesterol loading into glial cells is known to cluster inflammatory proteins and cause inflammation (69)”

    From Regulation of beta-amyloid production in neurons by astrocyte-derived cholesterol (2021) · cites this paper as [69]

    The Inflammaraft section describes cholesterol-rich lipid rafts in glial cells consolidating inflammatory signaling proteins and serving as platforms for inflammatory signaling. The Cholesterol efflux section reports increased raft cholesterol and TLR4 clustering after LPS stimulation. Neither passage establishes that cholesterol loading into glial cells alone causes the clustering or inflammation; the paper describes these changes in response to inflammatory stimuli. (LLM, conf=0.84)

    Experimental — accuracy not yet measured

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 135

  1. Simons, 1997, Functional rafts in cell membranes, Nature., 387, 569, 10.1038/42408 · DOI · Paper page
  2. Hanashima, 2019, Cholesterol-induced conformational change in the sphingomyelin headgroup, Biophys. J., 117, 307, 10.1016/j.bpj.2019.06.019 · DOI
  3. Lingwood, 2010, Lipid rafts as a membrane-organizing principle, Science., 327, 46, 10.1126/science.1174621 · DOI · Paper page
  4. Sezgin, 2017, The mystery of membrane organization: composition, regulation and roles of lipid rafts, Nat. Rev. Mol. Cell Biol., 18, 361, 10.1038/nrm.2017.16 · DOI · Paper page
  5. Robinson, 2019, Tools for understanding nanoscale lipid regulation of ion channels, Trends Biochem. Sci., 44, 795, 10.1016/j.tibs.2019.04.001 · DOI · Paper page
  6. Tanga, 2005, The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy, Proc. Natl. Acad. Sci. USA., 102, 5856, 10.1073/pnas.0501634102 · DOI · Paper page
  7. Sorge, 2011, Spinal cord Toll-like receptor 4 mediates inflammatory and neuropathic hypersensitivity in male but not female mice, J. Neurosci., 31, 15450, 10.1523/JNEUROSCI.3859-11.2011 · DOI
  8. Christianson, 2011, Spinal TLR4 mediates the transition to a persistent mechanical hypersensitivity after the resolution of inflammation in serum-transferred arthritis, Pain., 152, 2881, 10.1016/j.pain.2011.09.020 · DOI
  9. Woller, 2016, Systemic TAK-242 prevents intrathecal LPS evoked hyperalgesia in male, but not female mice and prevents delayed allodynia following intraplantar formalin in both male and female mice: the role of TLR4 in the evolution of a persistent pain state, Brain Behav. Immun., 56, 271, 10.1016/j.bbi.2016.03.026 · DOI
  10. Xu, 2011, A brief comparison of the pathophysiology of inflammatory versus neuropathic pain, Curr. Opin. Anaesthesiol., 24, 400, 10.1097/ACO.0b013e32834871df · DOI
  11. Woller, 2019, Neuraxial TNF and IFN-beta co-modulate persistent allodynia in arthritic mice, Brain Behav. Immun., 76, 151, 10.1016/j.bbi.2018.11.014 · DOI
  12. Ramachandran, 2019, Role of Toll-like receptor 4 signaling in mast cell-mediated migraine pain pathway, Mol. Pain., 15, 174, 10.1177/1744806919867842 · DOI
  13. Woller, 2015, Differences in cisplatin-induced mechanical allodynia in male and female mice, Eur. J. Pain., 19, 1476, 10.1002/ejp.679 · DOI
  14. Woller, 2017, An overview of pathways encoding nociception, Clin. Exp. Rheumatol., 35, 40
  15. Wolfe, 2007, Assessment of pain in rheumatoid arthritis: minimal clinically significant difference, predictors, and the effect of anti-tumor necrosis factor therapy, J. Rheumatol., 34, 1674
  16. Taylor, 2010, Patient perceptions concerning pain management in the treatment of rheumatoid arthritis, J. Int. Med. Res., 38, 1213, 10.1177/147323001003800402 · DOI
  17. Katz, 2009, Transition from acute to chronic postsurgical pain: risk factors and protective factors, Expert Rev. Neurother., 9, 723, 10.1586/ern.09.20 · DOI · Paper page
  18. Kehlet, 2010, Persistent postsurgical pain: the path forward through better design of clinical studies, Anesthesiology., 112, 514, 10.1097/ALN.0b013e3181cf423d · DOI
  19. Yaksh, 2015, The search for novel analgesics: targets and mechanisms, F1000Prime Rep., 7, 56, 10.12703/P7-56 · DOI
  20. Willemen, 2012, MicroRNA-124 as a novel treatment for persistent hyperalgesia, J. Neuroinflammation., 9, 143, 10.1186/1742-2094-9-143 · DOI · Paper page
  21. Mei, 2011, Post-injury administration of minocycline: an effective treatment for nerve-injury induced neuropathic pain, Neurosci. Res., 70, 305, 10.1016/j.neures.2011.03.012 · DOI
  22. Hua, 2005, Intrathecal minocycline attenuates peripheral inflammation-induced hyperalgesia by inhibiting p38 MAPK in spinal microglia, Eur. J. Neurosci., 22, 2431, 10.1111/j.1460-9568.2005.04451.x · DOI
  23. Möller, 2016, Critical data-based re-evaluation of minocycline as a putative specific microglia inhibitor, Glia., 64, 1788, 10.1002/glia.23007 · DOI
  24. Zhao, 2017, The role of microglia in the pathobiology of neuropathic pain development: what do we know?, Br. J. Anaesth., 118, 504, 10.1093/bja/aex006 · DOI
  25. Gregus, 2018, Inhibition of spinal 15-LOX-1 attenuates TLR4-dependent, nonsteroidal anti-inflammatory drug-unresponsive hyperalgesia in male rats, Pain., 159, 2620, 10.1097/j.pain.0000000000001373 · DOI
  26. Bruno, 2018, Targeting toll-like receptor-4 (TLR4)-an emerging therapeutic target for persistent pain states, Pain., 159, 1908, 10.1097/j.pain.0000000000001306 · DOI
  27. Robinson, 2014, Astrocytes, but not microglia, are activated in oxaliplatin and bortezomib-induced peripheral neuropathy in the rat, Neuroscience., 274, 308, 10.1016/j.neuroscience.2014.05.051 · DOI
  28. Makker, 2017, Characterisation of immune and neuroinflammatory changes associated with chemotherapy-induced peripheral neuropathy, PLoS One., 12, e0170814, 10.1371/journal.pone.0170814 · DOI
  29. Beh, 2019, Preventive hypothermia as a neuroprotective strategy for paclitaxel-induced peripheral neuropathy, Pain., 160, 1505, 10.1097/j.pain.0000000000001547 · DOI
  30. Hu, 2018, Triggering receptor expressed on myeloid cells 2 (TREM2) dependent microglial activation promotes cisplatin-induced peripheral neuropathy in mice, Brain Behav. Immun., 68, 132, 10.1016/j.bbi.2017.10.011 · DOI
  31. Fessler, 2011, Intracellular lipid flux and membrane microdomains as organizing principles in inflammatory cell signaling, J. Immunol., 187, 1529, 10.4049/jimmunol.1100253 · DOI
  32. Woller, 2018, Inhibition of neuroinflammation by AIBP: spinal effects upon facilitated pain states, Cell Reports., 23, 2667, 10.1016/j.celrep.2018.04.110 · DOI
  33. Powers, 2006, Oxidative stress generated by hemorrhagic shock recruits Toll-like receptor 4 to the plasma membrane in macrophages, J. Exp. Med., 203, 1951, 10.1084/jem.20060943 · DOI
  34. Yvan-Charvet, 2008, Increased inflammatory gene expression in ABC transporter-deficient macrophages: free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infiltration of atherosclerotic lesions, Circulation., 118, 1837, 10.1161/CIRCULATIONAHA.108.793869 · DOI · Paper page
  35. Martinon, 2002, The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-β, Mol. Cell., 10, 417, 10.1016/S1097-2765(02)00599-3 · DOI · Paper page
  36. Aureli, 2015, Lipid membrane domains in the brain, Biochim. Biophys. Acta., 1851, 1006, 10.1016/j.bbalip.2015.02.001 · DOI
  37. Zaidi, 2018, The plasma membrane calcium pumps-the old and the new, Neurosci. Lett., 663, 12, 10.1016/j.neulet.2017.09.066 · DOI
  38. Sághy, 2015, Evidence for the role of lipid rafts and sphingomyelin in Ca2+-gating of transient receptor potential channels in trigeminal sensory neurons and peripheral nerve terminals, Pharmacol. Res., 100, 101, 10.1016/j.phrs.2015.07.028 · DOI
  39. Schrattenholz, 2006, NMDA receptors are not alone: dynamic regulation of NMDA receptor structure and function by neuregulins and transient cholesterol-rich membrane domains leads to disease-specific nuances of glutamate-signalling, Curr. Top. Med. Chem., 6, 663, 10.2174/156802606776894519 · DOI
  40. Gnanasekaran, 2011, Lipid rafts control P2X3 receptor distribution and function in trigeminal sensory neurons of a transgenic migraine mouse model, Mol. Pain., 7, 77, 10.1186/1744-8069-7-77 · DOI
  41. Startek, 2019, Mouse TRPA1 function and membrane localization are modulated by direct interactions with cholesterol, eLife., 8, e46084, 10.7554/eLife.46084 · DOI
  42. Ruysschaert, 2015, Role of lipid microdomains in TLR-mediated signalling, Biochim. Biophys. Acta., 1848, 1860, 10.1016/j.bbamem.2015.03.014 · DOI
  43. Katritch, 2013, Structure-function of the G protein-coupled receptor superfamily, Annu. Rev. Pharmacol. Toxicol., 53, 531, 10.1146/annurev-pharmtox-032112-135923 · DOI
  44. Fantini, 2019, Cholesterol-recognition motifs in membrane proteins, Adv. Exp. Med. Biol., 1135, 3, 10.1007/978-3-030-14265-0_1 · DOI
  45. Yahi, 2014, Deciphering the glycolipid code of Alzheimer's and Parkinson's amyloid proteins allowed the creation of a universal ganglioside-binding peptide, PLoS One., 9, e104751, 10.1371/journal.pone.0104751 · DOI
  46. Levental, 2010, Greasing their way: lipid modifications determine protein association with membrane rafts, Biochemistry., 49, 6305, 10.1021/bi100882y · DOI
  47. Fernandez-Lizarbe, 2008, Lipid rafts regulate ethanol-induced activation of TLR4 signaling in murine macrophages, Mol. Immunol., 45, 2007, 10.1016/j.molimm.2007.10.025 · DOI
  48. Wong, 2009, Fatty acids modulate Toll-like receptor 4 activation through regulation of receptor dimerization and recruitment into lipid rafts in a reactive oxygen species-dependent manner, J. Biol. Chem., 284, 27384, 10.1074/jbc.M109.044065 · DOI
  49. Shridas, 2011, Group X secretory phospholipase A2 enhances TLR4 signaling in macrophages, J. Immunol., 187, 482, 10.4049/jimmunol.1003552 · DOI
  50. Cheng, 2012, Apolipoprotein A-I attenuates palmitate-mediated NF-kappaB activation by reducing Toll-like receptor-4 recruitment into lipid rafts, PLoS One., 7, e33917, 10.1371/journal.pone.0033917 · DOI
  51. Zhang, 2018, Apolipoprotein A-1 binding protein inhibits inflammatory signaling pathways by binding to apolipoprotein A-1 in THP-1 macrophages, Circ. J., 82, 1396, 10.1253/circj.CJ-17-0877 · DOI
  52. Wu, 2010, Intrathecal siRNA against Toll-like receptor 4 reduces nociception in a rat model of neuropathic pain, Int. J. Med. Sci., 7, 251, 10.7150/ijms.7.251 · DOI
  53. Cao, 2009, The contributing role of CD14 in toll-like receptor 4 dependent neuropathic pain, Neuroscience., 158, 896, 10.1016/j.neuroscience.2008.10.004 · DOI
  54. Stokes, 2013, Spinal toll-like receptor signaling and nociceptive processing: regulatory balance between TIRAP and TRIF cascades mediated by TNF and IFNbeta, Pain., 154, 733, 10.1016/j.pain.2013.01.012 · DOI
  55. Stokes, 2013, Toll-like receptor signaling adapter proteins govern spread of neuropathic pain and recovery following nerve injury in male mice, J. Neuroinflammation., 10, 148, 10.1186/1742-2094-10-148 · DOI
  56. Seretny, 2014, Incidence, prevalence, and predictors of chemotherapy-induced peripheral neuropathy: a systematic review and meta-analysis, Pain., 155, 2461, 10.1016/j.pain.2014.09.020 · DOI · Paper page
  57. Park, 2014, Toll-like receptor signaling regulates cisplatin-induced mechanical allodynia in mice, Cancer Chemother. Pharmacol., 73, 25, 10.1007/s00280-013-2304-9 · DOI
  58. Li, 2014, Toll-like receptor 4 signaling contributes to Paclitaxel-induced peripheral neuropathy, J. Pain., 15, 712, 10.1016/j.jpain.2014.04.001 · DOI
  59. Kobayashi, 2016, TREM2/DAP12 signal elicits proinflammatory response in microglia and exacerbates neuropathic pain, J. Neurosci., 36, 11138, 10.1523/JNEUROSCI.1238-16.2016 · DOI
  60. Sehgal, 2002, Cytokine signaling: STATS in plasma membrane rafts, J. Biol. Chem., 277, 12067, 10.1074/jbc.M200018200 · DOI
  61. Tsuda, 2009, IFN-γ receptor signaling mediates spinal microglia activation driving neuropathic pain, Proc. Natl. Acad. Sci. USA., 106, 8032, 10.1073/pnas.0810420106 · DOI
  62. Allsopp, 2010, Lipid raft association and cholesterol sensitivity of P2X1-4 receptors for ATP: chimeras and point mutants identify intracellular amino-terminal residues involved in lipid regulation of P2X1 receptors, J. Biol. Chem., 285, 32770, 10.1074/jbc.M110.148940 · DOI
  63. Salter, 2017, Microglia emerge as central players in brain disease, Nat. Med., 23, 1018, 10.1038/nm.4397 · DOI · Paper page
  64. Beggs, 2012, P2X4R+ microglia drive neuropathic pain, Nat. Neurosci., 15, 1068, 10.1038/nn.3155 · DOI
  65. Tsuda, 2003, P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury, Nature., 424, 778, 10.1038/nature01786 · DOI
  66. Toyomitsu, 2012, CCL2 promotes P2X4 receptor trafficking to the cell surface of microglia, Purinergic Signal., 8, 301, 10.1007/s11302-011-9288-x · DOI
  67. Trang, 2009, P2X4-receptor-mediated synthesis and release of brain-derived neurotrophic factor in microglia is dependent on calcium and p38-mitogen-activated protein kinase activation, J. Neurosci., 29, 3518, 10.1523/JNEUROSCI.5714-08.2009 · DOI
  68. Gonnord, 2009, Palmitoylation of the P2X7 receptor, an ATP-gated channel, controls its expression and association with lipid rafts, FASEB J., 23, 795, 10.1096/fj.08-114637 · DOI
  69. Weinhold, 2010, Interaction and interrelation of P2X7 and P2X4 receptor complexes in mouse lung epithelial cells, Cell. Mol. Life Sci., 67, 2631, 10.1007/s00018-010-0355-1 · DOI
  70. Murrell-Lagnado, 2017, Regulation of P2X purinergic receptor signaling by cholesterol, Curr. Top. Membr., 80, 211, 10.1016/bs.ctm.2017.05.004 · DOI
  71. Mapplebeck, 2018, Microglial P2X4R-evoked pain hypersensitivity is sexually dimorphic in rats, Pain., 159, 1752, 10.1097/j.pain.0000000000001265 · DOI
  72. Yu, 2019, P2Y12 regulates microglia activation and excitatory synaptic transmission in spinal lamina II neurons during neuropathic pain in rodents, Cell Death Dis., 10, 165, 10.1038/s41419-019-1425-4 · DOI
  73. Yi, 2018, P2Y12 receptor upregulation in satellite glial cells is involved in neuropathic pain induced by HIV glycoprotein 120 and 2′,3′-dideoxycytidine, Purinergic Signal., 14, 47, 10.1007/s11302-017-9594-z · DOI
  74. Savi, 2006, The active metabolite of clopidogrel disrupts P2Y12 receptor oligomers and partitions them out of lipid rafts, Proc. Natl. Acad. Sci. USA., 103, 11069, 10.1073/pnas.0510446103 · DOI
  75. Rabani, 2018, Impact of ticagrelor on P2Y1 and P2Y12 localization and on cholesterol levels in platelet plasma membrane, Platelets., 29, 709, 10.1080/09537104.2017.1356453 · DOI
  76. Burmeister, 2017, Human microglia and astrocytes constitutively express the neurokinin-1 receptor and functionally respond to substance P, J. Neuroinflammation., 14, 245, 10.1186/s12974-017-1012-5 · DOI
  77. Kondo, 2005, Inhibition by spinal mu- and delta-opioid agonists of afferent-evoked substance P release, J. Neurosci., 25, 3651, 10.1523/JNEUROSCI.0252-05.2005 · DOI
  78. Tumati, 2012, Tachykinin NK(1) receptor antagonist co-administration attenuates opioid withdrawal-mediated spinal microglia and astrocyte activation, Eur. J. Pharmacol., 684, 64, 10.1016/j.ejphar.2012.03.025 · DOI
  79. Monastyrskaya, 2005, The NK1 receptor localizes to the plasma membrane microdomains, and its activation is dependent on lipid raft integrity, J. Biol. Chem., 280, 7135, 10.1074/jbc.M405806200 · DOI
  80. Kim, 2010, NADPH oxidase 2-derived reactive oxygen species in spinal cord microglia contribute to peripheral nerve injury-induced neuropathic pain, Proc. Natl. Acad. Sci. USA., 107, 14851, 10.1073/pnas.1009926107 · DOI
  81. Lim, 2013, Toll-like receptor 2 mediates peripheral nerve injury-induced NADPH oxidase 2 expression in spinal cord microglia, J. Biol. Chem., 288, 7572, 10.1074/jbc.M112.414904 · DOI
  82. Dang, 2006, A specific p47phox -serine phosphorylated by convergent MAPKs mediates neutrophil NADPH oxidase priming at inflammatory sites, J. Clin. Invest., 116, 2033, 10.1172/JCI27544 · DOI
  83. Vilhardt, 2004, The phagocyte NADPH oxidase depends on cholesterol-enriched membrane microdomains for assembly, EMBO J., 23, 739, 10.1038/sj.emboj.7600066 · DOI
  84. Cheng, 2004, NOXO1, regulation of lipid binding, localization, and activation of Nox1 by the Phox homology (PX) domain, J. Biol. Chem., 279, 4737, 10.1074/jbc.M305968200 · DOI
  85. Kawahara, 2008, Phosphatidylinositol (4,5)-bisphosphate modulates Nox5 localization via an N-terminal polybasic region, Mol. Biol. Cell., 19, 4020, 10.1091/mbc.e07-12-1223 · DOI
  86. Bianco, 2009, Acid sphingomyelinase activity triggers microparticle release from glial cells, EMBO J., 28, 1043, 10.1038/emboj.2009.45 · DOI · Paper page
  87. Li, 2017, Microvesicles shed from microglia activated by the P2X7-p38 pathway are involved in neuropathic pain induced by spinal nerve ligation in rats, Purinergic Signal., 13, 13, 10.1007/s11302-016-9537-0 · DOI
  88. Verderio, 2012, Myeloid microvesicles are a marker and therapeutic target for neuroinflammation, Ann. Neurol., 72, 610, 10.1002/ana.23627 · DOI · Paper page
  89. Ibáñez, 2019, TLR4 participates in the transmission of ethanol-induced neuroinflammation via astrocyte-derived extracellular vesicles, J. Neuroinflammation., 16, 136, 10.1186/s12974-019-1529-x · DOI
  90. Kim, 2016, DJ-1 deficiency impairs glutamate uptake into astrocytes via the regulation of flotillin-1 and caveolin-1 expression, Sci. Rep., 6, 28823, 10.1038/srep28823 · DOI
  91. Kim, 2013, DJ-1 associates with lipid rafts by palmitoylation and regulates lipid rafts-dependent endocytosis in astrocytes, Hum. Mol. Genet., 22, 4805, 10.1093/hmg/ddt332 · DOI
  92. Park, 2009, Oxidative stress induces lipid-raft-mediated activation of Src homology 2 domain-containing protein-tyrosine phosphatase 2 in astrocytes, Free Radic. Biol. Med., 46, 1694, 10.1016/j.freeradbiomed.2009.03.026 · DOI
  93. Tian, 2010, Increased expression of cholesterol 24S-hydroxylase results in disruption of glial glutamate transporter EAAT2 association with lipid rafts: a potential role in Alzheimer's disease, J. Neurochem., 113, 978, 10.1111/j.1471-4159.2010.06661.x · DOI
  94. Fang, 2012, The chemokine, macrophage inflammatory protein-2gamma, reduces the expression of glutamate transporter-1 on astrocytes and increases neuronal sensitivity to glutamate excitotoxicity, J. Neuroinflammation., 9, 267, 10.1186/1742-2094-9-267 · DOI
  95. Gosselin, 2013, Extracellular microvesicles from astrocytes contain functional glutamate transporters: regulation by protein kinase C and cell activation, Front. Cell. Neurosci., 7, 251, 10.3389/fncel.2013.00251 · DOI
  96. Vance, 2010, Formation and function of apolipoprotein E-containing lipoproteins in the nervous system, Biochim. Biophys. Acta., 1801, 806, 10.1016/j.bbalip.2010.02.007 · DOI · Paper page
  97. Hirsch-Reinshagen, 2004, Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain, J. Biol. Chem., 279, 41197, 10.1074/jbc.M407962200 · DOI · Paper page
  98. Wahrle, 2004, ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE, J. Biol. Chem., 279, 40987, 10.1074/jbc.M407963200 · DOI · Paper page
  99. Abildayeva, 2006, 24(S)-hydroxycholesterol participates in a liver X receptor-controlled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux, J. Biol. Chem., 281, 12799, 10.1074/jbc.M601019200 · DOI · Paper page
  100. Spagnuolo, 2018, Brain-derived neurotrophic factor modulates cholesterol homeostasis and apolipoprotein E synthesis in human cell models of astrocytes and neurons, J. Cell. Physiol., 233, 6925, 10.1002/jcp.26480 · DOI
  101. Zelcer, 2006, Liver X receptors as integrators of metabolic and inflammatory signaling, J. Clin. Invest., 116, 607, 10.1172/JCI27883 · DOI · Paper page
  102. Xu, 2017, Liver X receptor α is involved in counteracting mechanical allodynia by inhibiting neuroinflammation in the spinal dorsal horn, Anesthesiology., 127, 534, 10.1097/ALN.0000000000001718 · DOI
  103. Karasinska, 2013, ABCA1 influences neuroinflammation and neuronal death, Neurobiol. Dis., 54, 445, 10.1016/j.nbd.2013.01.018 · DOI · Paper page
  104. Liu, 2018, Taraxasterol inhibits LPS-induced inflammatory response in BV2 microglia cells by activating LXRalpha, Front. Pharmacol., 9, 278, 10.3389/fphar.2018.00278 · DOI
  105. Fu, 2018, Platycodin D inhibits inflammatory response in LPS-stimulated primary rat microglia cells through activating LXRalpha-ABCA1 signaling pathway, Front. Immunol., 8, 1929, 10.3389/fimmu.2017.01929 · DOI
  106. Baranova, 2002, Lipopolysaccharide down regulates both scavenger receptor B1 and ATP binding cassette transporter A1 in RAW cells, Infect. Immun., 70, 2995, 10.1128/IAI.70.6.2995-3003.2002 · DOI
  107. Yin, 2010, ATP-binding membrane cassette transporter A1 (ABCA1): a possible link between inflammation and reverse cholesterol transport, Mol. Med., 16, 438, 10.2119/molmed.2010.00004 · DOI
  108. Zidovetzki, 2007, Use of cyclodextrins to manipulate plasma membrane cholesterol content: evidence, misconceptions and control strategies, Biochim. Biophys. Acta., 1768, 1311, 10.1016/j.bbamem.2007.03.026 · DOI
  109. Carneiro, 2019, Cyclodextrin-drug inclusion complexes: in vivo and in vitro approaches, Int. J. Mol. Sci., 20, E642, 10.3390/ijms20030642 · DOI
  110. de Oliveira, 2019, Comparison of antinociceptive effects of plain lidocaine versus lidocaine complexed with hydroxypropyl-beta-cyclodextrin in animal models of acute and persistent orofacial pain, Naunyn Schmiedebergs Arch. Pharmacol., 392, 573, 10.1007/s00210-018-01609-8 · DOI
  111. Ory, 2017, Intrathecal 2-hydroxypropyl-beta-cyclodextrin decreases neurological disease progression in Niemann-Pick disease, type C1: a non-randomised, open-label, phase 1–2 trial, Lancet., 390, 1758, 10.1016/S0140-6736(17)31465-4 · DOI
  112. Davidson, 2019, 2-Hydroxypropyl-beta-cyclodextrin is the active component in a triple combination formulation for treatment of Niemann-Pick C1 disease, Biochim. Biophys. Acta Mol. Cell Biol. Lipids., 1864, 1545, 10.1016/j.bbalip.2019.04.011 · DOI
  113. Zimmer, 2016, Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming, Sci. Transl. Med., 8, 333ra50, 10.1126/scitranslmed.aad6100 · DOI
  114. Antonopoulos, 2012, Statins as anti-inflammatory agents in atherogenesis: molecular mechanisms and lessons from the recent clinical trials, Curr. Pharm. Des., 18, 1519, 10.2174/138161212799504803 · DOI
  115. Peng, 2019, Lovastatin inhibits Toll-like receptor 4 signaling in microglia by targeting its co-receptor myeloid differentiation protein 2 and attenuates neuropathic pain, Brain Behav. Immun., 82, 432, 10.1016/j.bbi.2019.09.013 · DOI
  116. Pathak, 2014, Atorvastatin attenuates neuropathic pain in rat neuropathy model by down-regulating oxidative damage at peripheral, spinal and supraspinal levels, Neurochem. Int., 68, 1, 10.1016/j.neuint.2014.01.014 · DOI
  117. Shi, 2011, Statins alleviate experimental nerve injury-induced neuropathic pain, Pain., 152, 1033, 10.1016/j.pain.2011.01.006 · DOI
  118. Kuipers, 2006, Simvastatin affects cell motility and actin cytoskeleton distribution of microglia, Glia., 53, 115, 10.1002/glia.20269 · DOI
  119. Kuipers, 2005, Statins affect cell-surface expression of major histocompatibility complex class II molecules by disrupting cholesterol-containing microdomains, Hum. Immunol., 66, 653, 10.1016/j.humimm.2005.04.004 · DOI
  120. Ohkawa, 2015, Ganglioside GD3 enhances invasiveness of gliomas by forming a complex with platelet-derived growth factor receptor alpha and yes kinase, J. Biol. Chem., 290, 16043, 10.1074/jbc.M114.635755 · DOI
  121. Ohmi, 2011, Gangliosides are essential in the protection of inflammation and neurodegeneration via maintenance of lipid rafts: elucidation by a series of ganglioside-deficient mutant mice, J. Neurochem., 116, 926, 10.1111/j.1471-4159.2010.07067.x · DOI
  122. Kawashita, 2016, Enhancement by uridine diphosphate of macrophage inflammatory protein-1 alpha production in microglia derived from Sandhoff disease model mice, JIMD Rep., 28, 85, 10.1007/8904_2015_496 · DOI
  123. Kim, 2006, Raft-mediated Src homology 2 domain-containing proteintyrosine phosphatase 2 (SHP-2) regulation in microglia, J. Biol. Chem., 281, 11872, 10.1074/jbc.M511706200 · DOI
  124. Beckmann, 2014, Inhibition of acid sphingomyelinase by tricyclic antidepressants and analogons, Front. Physiol., 5, 331, 10.3389/fphys.2014.00331 · DOI
  125. Patti, 2012, Metabolomics implicates altered sphingolipids in chronic pain of neuropathic origin, Nat. Chem. Biol., 8, 232, 10.1038/nchembio.767 · DOI
  126. Lee, 2007, Multiple actions of dimethylsphingosine in 1321N1 astrocytes, Mol. Cells., 23, 11, 10.1016/S1016-8478(23)07383-1 · DOI
  127. Kobayashi, 2012, The critical role of spinal ceramide in the development of partial sciatic nerve ligation-induced neuropathic pain in mice, Biochem. Biophys. Res. Commun., 421, 318, 10.1016/j.bbrc.2012.03.153 · DOI
  128. Díaz, 2018, “Lipid raft aging” in the human frontal cortex during nonpathological aging: gender influences and potential implications in Alzheimer's disease, Neurobiol. Aging., 67, 42, 10.1016/j.neurobiolaging.2018.02.022 · DOI
  129. Galambos, 1961, A glia-neural theory of brain function, Proc. Natl. Acad. Sci. USA., 47, 129, 10.1073/pnas.47.1.129 · DOI
  130. Baral, 2019, Pain and immunity: implications for host defence, Nat. Rev. Immunol., 19, 433, 10.1038/s41577-019-0147-2 · DOI
  131. Fernandez-Lizarbe, 2013, Ethanol induces TLR4/TLR2 association, triggering an inflammatory response in microglial cells, J. Neurochem., 126, 261, 10.1111/jnc.12276 · DOI
  132. Shmuel-Galia, 2017, Intramembrane attenuation of the TLR4-TLR6 dimer impairs receptor assembly and reduces microglia-mediated neurodegeneration, J. Biol. Chem., 292, 13415, 10.1074/jbc.M117.784983 · DOI
  133. Schilling, 2010, Importance of lipid rafts for lysophosphatidylcholine-induced caspase-1 activation and reactive oxygen species generation, Cell. Immunol., 265, 87, 10.1016/j.cellimm.2010.08.003 · DOI
  134. Trudler, 2014, DJ-1 deficiency triggers microglia sensitivity to dopamine toward a pro-inflammatory phenotype that is attenuated by rasagiline, J. Neurochem., 129, 434, 10.1111/jnc.12633 · DOI
  135. Wang, 2014, Toll-like receptor 2/4 heterodimer mediates inflammatory injury in intracerebral hemorrhage, Ann. Neurol., 75, 876, 10.1002/ana.24159 · DOI

Cited by

Sorted by citations

Metadata

Authors
Miller, Y. I., Navia-Pelaez, J. M., Corr, M., & Yaksh, T. L.
ORCID
Miller, Yury I.
Venue
Journal of Lipid Research
Publisher
Elsevier BV
Published
2020-05
Volume
61
Issue
5
Pages
655-666
ISSN
0022-2275
DOI
10.1194/jlr.tr119000468
Cited by
112
References
6
Language
en
Licence
Funders
National Institutes of Health (NS102432, HL135737, HL136275, NS104769, NS099338, T32AR064194)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review