The DOI matches its OpenAlex record; 119 of the 119 references it cites were found in a registry or an index.
Weight Loss in Breast Cancer Patient Management
Abstract
PURPOSE: To systematically review and summarize evidence relevant to obesity and breast cancer clinical outcome, potential hormonal mediating mechanisms, and the current status of weight loss interventions for chronic disease management. METHODS: A comprehensive, formal literature review was conducted to identify 5,687 citations with key information from 159 references summarized in text and tables. This process included a search for all breast cancer studies exploring associations among survival or recurrence and obesity at diagnosis or weight gain after diagnosis using prospective criteria. RESULTS: On the basis of observational studies, women with breast cancer who are overweight or gain weight after diagnosis are found to be at greater risk for breast cancer recurrence and death compared with lighter women. Obesity is also associated with hormonal profiles likely to stimulate breast cancer growth. Recently, use of weight loss algorithms proven successful in other clinical settings that incorporate dietary therapy, physical activity, and ongoing behavior therapy have been endorsed by the National Institutes of Health and other health agencies. CONCLUSION: Although definitive weight loss intervention trials in breast cancer patients remain to be conducted, the current evidence relating increased body weight to adverse breast cancer outcome and the documented favorable effects of weight loss on clinical outcome in other comorbid conditions support consideration of programs for weight loss in breast cancer patients. Recommendations for the clinical care of overweight or obese breast cancer patients are offered.
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Cites
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Tamoxifen for early breast cancer: an overview of the randomised trials
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Role of the Insulin-Like Growth Factor Family in Cancer Development and Progression
Yu, H. (2000) · Journal of the National Cancer Institute · doi:10.1093/jnci/92.18.1472 · Cited by 1,424
Key, T. J., Verkasalo, P. K., & Banks, E. (2001) · The Lancet Oncology · doi:10.1016/s1470-2045(00)00254-0 · Cited by 1,261
Estrogen and the Risk of Breast Cancer
Clemons, M., & Goss, P. (2001) · New England Journal of Medicine · doi:10.1056/nejm200101253440407 · Cited by 1,096
Fasting Insulin and Outcome in Early-Stage Breast Cancer: Results of a Prospective Cohort Study
Goodwin, P. J., Ennis, M., Pritchard, K. I., Trudeau, M. E., Koo, J., Madarnas, Y., Hartwick, W., Hoffman, B., & Hood, N. (2002) · Journal of Clinical Oncology · doi:10.1200/jco.20.1.42 · Cited by 981
Effect of Age and Comorbidity in Postmenopausal Breast Cancer Patients Aged 55 Years and Older
Yancik, R. (2001) · JAMA · doi:10.1001/jama.285.7.885 · Cited by 896
Plasma Sex Steroid Hormone Levels and Risk of Breast Cancer in Postmenopausal Women
Hankinson, S. E., Willett, W. C., Manson, J. E., Colditz, G. A., Hunter, D. J., Spiegelman, D., Barbieri, R. L., & Speizer, F. E. (1998) · JNCI: Journal of the National Cancer Institute · doi:10.1093/jnci/90.17.1292 · Cited by 687
Cited by
Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms
Calle, E. E., & Kaaks, R. (2004) · Nature reviews. Cancer · doi:10.1038/nrc1408 · Cited by 3,613
Early breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
Cardoso, F., Kyriakides, S., Ohno, S., Penault-Llorca, F., Poortmans, P., Rubio, I. T., Zackrisson, S., & Senkus, E. (2019) · Annals of Oncology · doi:10.1093/annonc/mdz173 · Cited by 2,214
Nutrition and physical activity guidelines for cancer survivors
Rock, C. L., Doyle, C., Demark‐Wahnefried, W., Meyerhardt, J., Courneya, K. S., Schwartz, A. L., Bandera, E. V., Hamilton, K. K., Grant, B., McCullough, M., et al. (2012) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21142 · Cited by 1,995
“Indeed, given accumulating data to suggest that overweight and obesity adversely influence not only cancer-specific outcomes but also overall health and quality of life, weight management is now considered a priority standard of care for overweight women diagnosed with early stage breast cancer.(8,192) A decade of pre…”
BackgroundPhysical activity and survival after breast cancer diagnosis
Holmes, M. D. (2005) · JAMA · doi:10.1001/jama.293.20.2479 · Cited by 1,772
Riding the Crest of the Teachable Moment: Promoting Long-Term Health After the Diagnosis of Cancer
Demark-Wahnefried, W., Aziz, N. M., Rowland, J. H., & Pinto, B. M. (2005) · Journal of Clinical Oncology · doi:10.1200/jco.2005.01.230 · Cited by 1,119
Metadata
- Authors
- Chlebowski, R. T., Aiello, E. J., & McTiernan, A.
- Venue
- Journal of Clinical Oncology
- Publisher
- Lippincott Williams & Wilkins
- Published
- 2002-02-15
- Volume
- 20
- Issue
- 4
- Pages
- 1128-1143
- ISSN
- 0732-183X (ISSN-L)
- OpenAlex
- W2067815741
- Cited by
- 623
- References
- 119
- FWCI
- 9.87
- Type
- journal article
- Language
- en
- Open access
- closed
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- Chlebowski, R. T., Aiello, E. J., & McTiernan, A. (2002). Weight Loss in Breast Cancer Patient Management. Journal of Clinical Oncology. https://doi.org/10.1200/jco.20.4.1128
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
