Impact of an Automatically Generated Cancer Survivorship Care Plan on Patient-Reported Outcomes in Routine Clinical Practice: Longitudinal Outcomes of a Pragmatic, Cluster Randomized Trial

Nicolaije, Kim A.H.; Ezendam, Nicole P.M.; Vos, M. Caroline; Pijnenborg, Johanna M.A.; Boll, Dorry; Boss, Erik A.; Hermans, Ralph H.M.; Engelhart, Karin C.M.; Haartsen, Joke E.; Pijlman, Brenda M.; van Loon-Baelemans, Ingrid E.A.M.; Mertens, Helena J.M.M.; Nolting, Willem E.; van Beek, Johannes J.; Roukema, Jan A.; Zijlstra, Wobbe P.; Kruitwagen, Roy F.P.M.; van de Poll-Franse, Lonneke V.

doi:10.1200/jco.2014.60.3399

Cited by 112Cancer survivorship and carePatient-Provider Communication in HealthcarePatient Satisfaction in Healthcare

Impact of an Automatically Generated Cancer Survivorship Care Plan on Patient-Reported Outcomes in Routine Clinical Practice: Longitudinal Outcomes of a Pragmatic, Cluster Randomized Trial

Nicolaije, Kim A.H., Ezendam, Nicole P.M., Vos, M. Caroline, Pijnenborg, Johanna M.A., Boll, Dorry, Boss, Erik A., Hermans, Ralph H.M., Engelhart, Karin C.M. +10 more·2015·Journal of Clinical Oncology

DOI 10.1200/jco.2014.60.3399

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Abstract

Purpose: This study was conducted to longitudinally assess the impact of an automatically generated survivorship care plan (SCP) on patient-reported outcomes in routine clinical practice. Primary outcomes were patient satisfaction with information and care. Secondary outcomes included illness perceptions and health care use. Methods: Twelve hospitals were randomly assigned to SCP care or usual care in a pragmatic, cluster randomized trial. Newly diagnosed patients with endometrial cancer completed questionnaires after diagnosis (n = 221; 75% response), 6 months (n = 158), and 12 months (n = 147). An SCP application was built in the Web-based ROGY (Registration System Oncological Gynecology). By clicking the SCP button, a patient-tailored SCP was generated. Results: In the SCP care arm, 74% of patients received an SCP. They reported receiving more information about their treatment (mean [M] = 57, standard deviation [SD] = 20 v M = 47, SD = 24; P = .03), other services (M = 35, SD = 22 v M = 25, SD = 22; P = .03), and different places of care (M = 27, SD = 25 v M = 23, SD = 26; P = .04) than the usual care arm (scales, 0 to 100). However, there were no differences regarding satisfaction with information or care. Patients in the SCP care arm experienced more symptoms (M = 3.3, SD = 2.0 v M = 2.6, SD = 1.6; P = .03), were more concerned about their illness (M = 4.4, SD = 2.3 v M = 3.9, SD = 2.1; P = .03), were more affected emotionally (M = 4.0, SD = 2.2 v M = 3.7, SD = 2.2; P = .046), and reported more cancer-related contact with their primary care physician (M = 1.8, SD = 2.0 v M = 1.1, SD = 0.9; P = .003) than those in the usual care arm (scale, 1 to 10). These effects did not differ over time. Conclusion: The present trial showed no evidence of a benefit of SCPs on satisfaction with information and care. Furthermore, SCPs increased patients' concerns, emotional impact, experienced symptoms, and the amount of cancer-related contact with the primary care physician. Whether this may ultimately lead to more empowered patients should be investigated further.

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Delivery of SCPs resulted in survivors reporting a greater amount of information received.
“Consistent with this view are results described in the current article showing delivery of SCPs resulted in survivors reporting a greater amount of information received34 and greater likelihood of survivors correctly identifying their PCP as responsible for follow-up care.23”
From Systematic Review of the Impact of Cancer Survivorship Care Plans on Health Outcomes and Health Care Delivery (2018) · cites this paper as [34]

Consort 2010 statement: extension to cluster randomised trials
Campbell, M. K., Piaggio, G., Elbourne, D. R., Altman, D. G., & for the CONSORT Group (2012) · BMJ · doi:10.1136/bmj.e5661 · Cited by 3,510 · see citing works
The Brief Illness Perception Questionnaire
Broadbent, E., Petrie, K. J., Main, J., & Weinman, J. (2006) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2005.10.020 · Cited by 3,431 · see citing works
From Cancer Patient to Cancer Survivor: Lost in Transition
(2005) · PsycEXTRA Dataset · doi:10.1037/e720092007-001 · Cited by 2,364 · see citing works
Global estimates of cancer prevalence for 27 sites in the adult population in 2008
Bray, F., Ren, J., Masuyer, E., & Ferlay, J. (2012) · International Journal of Cancer · doi:10.1002/ijc.27711 · Cited by 1,893 · see citing works
Improving the reporting of pragmatic trials: An extension of the CONSORT statement
Zwarenstein, M., Treweek, S., Gagnier, J. J., Altman, D. G., Tunis, S., Haynes, B., Oxman, A. D., Moher, D., & groups, F. T. C. A. P. T. I. H. (. (2008) · BMJ · doi:10.1136/bmj.a2390 · Cited by 1,813 · see citing works
The self‐administered comorbidity questionnaire: A new method to assess comorbidity for clinical and health services research
Sangha, O., Stucki, G., Liang, M. H., Fossel, A. H., & Katz, J. N. (2003) · Arthritis Care & Research · doi:10.1002/art.10993 · Cited by 1,799 · see citing works
Applied Multilevel Analysis
Twisk, J. W. R. (2006) · Cambridge University Press eBooks · doi:10.1017/cbo9780511610806 · Cited by 692 · see citing works
The Patient-Centered Outcomes Research Institute (PCORI) National Priorities for Research and Initial Research Agenda
Beal, A. C. (2012) · JAMA · doi:10.1001/jama.2012.500 · Cited by 625 · see citing works
The PCORI Perspective on Patient-Centered Outcomes Research
Frank, L. B., Basch, E., & Selby, J. V. (2014) · JAMA · doi:10.1001/jama.2014.11100 · Cited by 585 · see citing works
Randomized Trial of Long-Term Follow-Up for Early-Stage Breast Cancer: A Comparison of Family Physician Versus Specialist Care
Grunfeld, E., Levine, M. N., Julian, J. A., Coyle, D., Szechtman, B., Mirsky, D., Verma, S., Dent, S. F., Sawka, C. A., Pritchard, K. I., et al. (2006) · Journal of Clinical Oncology · doi:10.1200/jco.2005.03.2235 · Cited by 541 · see citing works
The relation between information provision and health-related quality of life, anxiety and depression among cancer survivors: a systematic review
Husson, O., Mols, F., & van de Poll-Franse, L. V. (2011) · Annals of Oncology · doi:10.1093/annonc/mdq413 · Cited by 535 · cited 1× · see citing works
“01 II 5 (4) 2 (2) 7 (3) 10 (14) II 8 (7) 7 (7) 15 (7) 11 (15) IV 3 (3) 4 (4) 7 (3) 1 (1) Treatment Surgery 117 (99) 97 (98) .”
Future supply and demand for oncologists: challenges to assuring access to oncology services
Erikson, C., Salsberg, E., Forte, G., Bruinooge, S., & Goldstein, M. (2007) · Journal of Oncology Practice · doi:10.1200/jop.0723601 · Cited by 528 · see citing works
Multilevel Analysis for Applied Research: It's Just Regression!
Bickel, R. N. (2007) · Cited by 405 · see citing works
The Patient Reported Outcomes Following Initial treatment and Long term Evaluation of Survivorship registry: Scope, rationale and design of an infrastructure for the study of physical and psychosocial outcomes in cancer survivorship cohorts
van de Poll-Franse, L. V., Horevoorts, N. J. E., van Eenbergen, M. C. H. J., Denollet, J., Roukema, J. A., Aaronson, N. K., Vingerhoets, A. J. J. M., Coebergh, J. W. W., Vries, J. D., Essink‐Bot, M., et al. (2011) · European Journal of Cancer · doi:10.1016/j.ejca.2011.04.034 · Cited by 399 · see citing works
Self-citation
Applied Multilevel Analysis: A Practical Guide for Medical Researchers
Twisk, J. W. R. (2006) · Cited by 370 · see citing works
Evaluating Survivorship Care Plans: Results of a Randomized, Clinical Trial of Patients With Breast Cancer
Grunfeld, E., Julian, J. A., Pond, G. R., Maunsell, E., Coyle, D., Folkes, A., Joy, A. A., Provencher, L., Rayson, D., Rheaume, D., et al. (2011) · Journal of Clinical Oncology · doi:10.1200/jco.2011.36.8373 · Cited by 315 · see citing works
Multilevel Analysis for Applied Research: It's Just Regression
Furlow, C. F., & Gagné, P. (2008) · Structural Equation Modeling A Multidisciplinary Journal · doi:10.1080/10705510801922670 · Cited by 296 · see citing works
Patient-centered care and breast cancer survivors’ satisfaction with information
Mallinger, J. B., Griggs, J. J., & Shields, C. G. (2004) · Patient Education and Counseling · doi:10.1016/j.pec.2004.09.009 · Cited by 288 · see citing works
Implementing a Survivorship Care Plan for Patients With Breast Cancer
Ganz, P. A., & Hahn, E. E. (2008) · Journal of Clinical Oncology · doi:10.1200/jco.2007.14.2851 · Cited by 259 · see citing works
Survivorship care plans in research and practice
Salz, T., Oeffinger, K. C., McCabe, M. S., Layne, T. M., & Bach, P. B. (2012) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.20142 · Cited by 241 · see citing works
An international prospective study of the EORTC cancer in-patient satisfaction with care measure (EORTC IN-PATSAT32)
Brédart, A., Bottomley, A., Blazeby, J. M., Conroy, T., Coens, C., D’Haese, S., Chie, W., Hammerlid, E. B., Arrarás, J. I., Efficace, F., et al. (2005) · European Journal of Cancer · doi:10.1016/j.ejca.2005.04.041 · Cited by 235 · see citing works
An international validation study of the EORTC QLQ-INFO25 questionnaire: An instrument to assess the information given to cancer patients
Arrarás, J. I., Greimel, E., Sezer, O., Chie, W., Bergenmar, M., Costantini, A., Young, T., Kuljanić, K., & Velikova, G. (2010) · European Journal of Cancer · doi:10.1016/j.ejca.2010.06.118 · Cited by 200 · see citing works
Multiple imputation of missing repeated outcome measurements did not add to linear mixed-effects models
Peters, S. A. E., Bots, M. L., den Ruijter, H. M., Palmer, M. K., Grobbee, D. E., Crouse, J. R., O’Leary, D. H., Evans, G. W., Raichlen, J. S., Moons, K. G. M., et al. (2012) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2011.11.012 · Cited by 165 · see citing works
Summing it up: An integrative review of studies of cancer survivorship care plans (2006‐2013)
Mayer, D. K., Birken, S. A., Check, D. K., & Chen, R. C. (2014) · Cancer · doi:10.1002/cncr.28884 · Cited by 156 · see citing works
Direct likelihood analysis versus simple forms of imputation for missing data in randomized clinical trials
Beunckens, C., Molenberghs, G., & Kenward, M. G. (2005) · Clinical Trials · doi:10.1191/1740774505cn119oa · Cited by 152 · see citing works
Randomized controlled trial of a clinic-based survivorship intervention following adjuvant therapy in breast cancer survivors
Hershman, D. L., Greenlee, H., Awad, D., Kalinsky, K. M., Maurer, M., Kranwinkel, G., Brafman, L., Jayasena, R. M. D., Tsai, W., Neugut, A. I., et al. (2013) · Breast Cancer Research and Treatment · doi:10.1007/s10549-013-2486-1 · Cited by 117 · see citing works
Do survivorship care plans impact patients' evaluations of care? A randomized evaluation with gynecologic oncology patients
Brothers, B. M., Easley, A., Salani, R., & Andersen, B. L. (2013) · Gynecologic Oncology · doi:10.1016/j.ygyno.2013.02.037 · Cited by 91 · see citing works
Ethics, Regulation, and Comparative Effectiveness Research
Platt, R., KASS, N. E., & McGraw, D. (2014) · JAMA · doi:10.1001/jama.2014.2144 · Cited by 64 · see citing works
Is It Time for (Survivorship Care) Plan B?
Smith, T. J., & Snyder, C. F. (2011) · Journal of Clinical Oncology · doi:10.1200/jco.2011.38.8397 · Cited by 56 · see citing works
The impact of a cancer Survivorship Care Plan on gynecological cancer patient and health care provider reported outcomes (ROGY Care): study protocol for a pragmatic cluster randomized controlled trial
van de Poll-Franse, L. V., Nicolaije, K. A. H., Vos, M. C., Pijnenborg, J. M. A., Boll, D., Husson, O., Ezendam, N. P. M., Boss, E. A., Hermans, R. H. M., Engelhart, K. C. M., et al. (2011) · Trials · doi:10.1186/1745-6215-12-256 · Cited by 45 · see citing works
Self-citation
Survivorship Care Plans: An Argument for Evidence Over Common Sense
Stricker, C. T., Jacobs, L. A., & Palmer, S. C. (2012) · Journal of Clinical Oncology · doi:10.1200/jco.2011.40.7940 · Cited by 40 · see citing works
Survivorship Care Plans to inform the primary care physician: results from the ROGY care pragmatic cluster randomized controlled trial
Ezendam, N. P. M., Nicolaije, K. A. H., Kruitwagen, R. F. P. M., Pijnenborg, J. M. A., Vos, M. D., Boll, D., van Bommel, M., & van de Poll-Franse, L. V. (2014) · Journal of Cancer Survivorship · doi:10.1007/s11764-014-0368-0 · Cited by 38 · see citing works
Self-citation
Improving Survivorship Care
Jefford, M., Schofield, P. E., & Emery, J. D. (2012) · Journal of Clinical Oncology · doi:10.1200/jco.2011.40.5886 · Cited by 29 · see citing works
Oncology providers’ evaluation of the use of an automatically generated cancer survivorship care plan: longitudinal results from the ROGY Care trial
Nicolaije, K. A. H., Ezendam, N. P. M., Vos, M. D., Pijnenborg, J. M. A., van de Poll-Franse, L. V., & Kruitwagen, R. F. P. M. (2013) · Journal of Cancer Survivorship · doi:10.1007/s11764-013-0327-1 · Cited by 27 · see citing works
Self-citation
‘They’re survivors physically but we want them to survive mentally as well’: health care professionals’ views on providing potential late effect information
Cox, A., & Faithfull, S. (2013) · Supportive Care in Cancer · doi:10.1007/s00520-013-1806-7 · Cited by 21 · see citing works

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Systematic Review of the Impact of Cancer Survivorship Care Plans on Health Outcomes and Health Care Delivery
Jacobsen, P. B., DeRosa, A. P., Henderson, T. O., Mayer, D. K., Moskowitz, C. S., Paskett, E. D., & Rowland, J. H. (2018) · Journal of Clinical Oncology · doi:10.1200/jco.2018.77.7482 · Cited by 274 · see citing works
Empowering survivors after colorectal and lung cancer treatment: Pilot study of a Self-Management Survivorship Care Planning intervention
Reb, A., Ruel, N., Fakih, M., Lai, L., Salgia, R., Ferrell, B., Sampath, S., Kim, J. Y., Raz, D. J., & Sun, V. (2017) · European Journal of Oncology Nursing · doi:10.1016/j.ejon.2017.06.003 · Cited by 45 · see citing works
Avoiding Implementation Errors in Cancer Survivorship Care Plan Effectiveness Studies
Mayer, D. K., Birken, S. A., & Chen, R. C. (2015) · Journal of Clinical Oncology · doi:10.1200/jco.2015.62.6937 · Cited by 31 · see citing works
Long-term effectiveness of an E-based survivorship care plan for breast cancer survivors: A quasi-experimental study.
Fang, S.-Y., Wang, Y.-L., Lu, W.-H., Lee, K.-T., Kuo, Y.-L., & Fetzer, S. J. (2020) · Patient Education and Counseling · doi:10.1016/j.pec.2019.09.012 · Cited by 24 · see citing works
Survivorship Care Plans: Reaching a Benchmark and Striving to Achieve Intent
Stuver, R., Faig, J., Cadorette, M., Decaneas, W., Kaplan, I., VanDeWege, C., Weden, V., Kent, M., & Zerillo, J. A. (2020) · JCO Oncology Practice · doi:10.1200/op.20.00092 · Cited by 5 · see citing works

Authors: Nicolaije, K. A. H., Ezendam, N. P. M., Vos, M. C., Pijnenborg, J. M. A., Boll, D., Boss, E. A., Hermans, R. H. M., Engelhart, K. C. M., Haartsen, J. E., Pijlman, B. M., van Loon-Baelemans, I. E. A. M., Mertens, H. J. M. M., Nolting, W. E., van Beek, J. J., Roukema, J. A., Zijlstra, W. P., Kruitwagen, R. F. P. M., & van de Poll-Franse, L. V.
Affiliations: Tilburg University (NL)
Kim A.H. Nicolaije, Nicole P.M. Ezendam, Wobbe P. Zijlstra, and Lonneke V. van de Poll-Franse, Tilburg University, Tilburg; Kim A.H. Nicolaije, Nicole P.M. Ezendam, and Lonneke V. van de Poll-Franse, Comprehensive Cancer Center the Netherlands, Eindhoven; M. Caroline Vos and Dorry Boll, Elisabeth-TweeSteden Hospital, Tilburg and Waalwijk; Erik A. Boss, Maxima Medical Center, Veldhoven and Eindhoven, the Netherlands; Ralph H.M. Hermans, Catharina Hospital, Eindhoven; Karin C.M. Engelhart, St Anna Hospital...
ORCID: Nicolaije, Kim A.H.
Ezendam, Nicole P.M.
Vos, M. Caroline
Pijnenborg, Johanna M.A.
Boll, Dorry
Pijlman, Brenda M.
Kruitwagen, Roy F.P.M.
Venue: Journal of Clinical Oncology
Publisher: American Society of Clinical Oncology (ASCO)
Published: 2015-11-01
Volume: 33
Issue: 31
Pages: 3550-3559
ISSN: 0732-183X (ISSN-L)
1527-7755
DOI: 10.1200/jco.2014.60.3399
OpenAlex: W2153716218
Cited by: 112
References: 35
Citations by year: 2026: 3 · 2025: 4 · 2024: 4 · 2023: 6 · 2022: 5 · 2021: 11 · 2020: 11 · 2019: 11 · 2018: 23 · 2017: 14 · 2016: 19 · 2015: 1
FWCI: 8.30
Type: journal article
Language: en
Open access: closed
Locations: Journal of Clinical Oncology (publishedVersion)
Research portal (Tilburg University) (publishedVersion)
PubMed (publishedVersion)
Data Archiving and Networked Services (DANS) (submittedVersion)
Research Publications (Maastricht University) (submittedVersion)
Topics: Health Sciences › Medicine › Oncology › Cancer survivorship and care
Health Sciences › Health Professions › General Health Professions › Patient-Provider Communication in Healthcare
Health Sciences › Health Professions › General Health Professions › Patient Satisfaction in Healthcare
Keywords: cancer survivorship care plans, endometrial cancer, patient-reported outcomes, patient satisfaction, illness perception, health care utilization, symptom burden, emotional distress, gynecologic oncology, routine clinical practice, longitudinal outcomes, newly diagnosed cancer
MeSH terms: Aged, Automation, Female, Humans, Longitudinal Studies, Medical Oncology, Middle Aged, Netherlands, Patient Care Planning, Physician-Patient Relations, Surveys and Questionnaires, Registries, Social Class, Software, Time Factors, Endometrial Neoplasms, Patient Satisfaction, Survivors, Physicians, Primary Care, Patient Outcome Assessment

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Impact of an Automatically Generated Cancer Survivorship Care Plan on Patient-Reported Outcomes in Routine Clinical Practice: Longitudinal Outcomes of a Pragmatic, Cluster Randomized Trial

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