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Cited by 484

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Early Alteration of Structural and Functional Brain Development in Premature Infants Born with Intrauterine Growth Restriction

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Tolsa, Cristina Borradori, Zimine, Slava, Warfield, Simon K, Freschi, Monica, Rossignol, Ana Sancho, Lazeyras, Francois, Hanquinet, Sylviane, Pfizenmaier, Mirjam, Hüppi, Petra S·2004·Pediatric Research
DOI 10.1203/01.pdr.0000128983.54614.7e
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Abstract

Placental insufficiency with fetal intrauterine growth restriction (IUGR) is an important cause of perinatal mortality and morbidity and is subsequently associated with significant neurodevelopmental impairment in cognitive function, attention capacity, and school performance. The underlying biologic cause for this association is unclear. Twenty-eight preterm infants (gestational age 32.5 ± 1.9 wk) were studied by early and term magnetic resonance imaging (MRI). An advanced quantitative volumetric three-dimensional MRI technique was used to measure brain tissue volumes in 14 premature infants with placental insufficiency, defined by abnormal antenatal Doppler measurements and mean birth weights <10th percentile (1246 ± 299 g) (IUGR) and in 14 preterm infants matched for gestational age with normal mean birth weights 1843 ± 246 g (control). Functional outcome was measured at term in all infants by a specialized assessment scale of preterm infant behavior. Premature infants with IUGR had a significant reduction in intracranial volume (mean ± SD: 253.7 ± 29.9 versus 300.5 ± 43.5 mL, p < 0.01) and in cerebral cortical gray matter (mean ± SD: 77.2 ± 16.3 versus 106.8 ± 24.6 mL, p < 0.01) when measured within the first 2 wk of life compared with control premature infants. These findings persisted at term with intracranial volume (mean ± SD: 429.3 ± 47.9 versus 475.9 ± 53.4 mL, p < 0.05) and cerebral cortical gray matter (mean ± SD: 149.3 ± 29.2 versus 189 ± 34.2 mL, p < 0.01). Behavioral assessment at term showed a significantly less mature score in the subsystem of attention-interaction availability in IUGR infants (p ± 0.01). Cerebral cortical gray matter volume at term correlated with attention-interaction capacity measured at term (r = 0.45, p < 0.05). These results suggest that placental insufficiency with IUGR have specific structural and functional consequences on cerebral cortical brain development. These findings may provide insight into the structural-functional correlate for the developmental deficits associated with IUGR.

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Research works printed but not linked: 51

  1. Toft PB, 1999, Pediatr Neurol, 21, 602, 10.1016/S0887-8994(99)00046-6 · DOI
  2. Kok JH, 1998, Br J Obstet Gynaecol, 105, 162, 10.1111/j.1471-0528.1998.tb10046.x · DOI · Paper page
  3. Seckl JR, 2000, Kidney Int, 57, 1412, 10.1046/j.1523-1755.2000.00984.x · DOI · Paper page
  4. Newnham J, 1998, Curr Opin Obstet Gynecol, 10, 145, 10.1097/00001703-199804000-00011 · DOI
  5. McMillen IC, 2001, Reproduction, 122, 195, 10.1530/rep.0.1220195 · DOI · Paper page
  6. Gluckmann PD, 1997, Acta Paediatr Suppl, 422, 69, 10.1111/j.1651-2227.1997.tb18349.x · DOI
  7. Seckl JR, 1997, Steroids, 62, 89, 10.1016/S0039-128X(96)00165-1 · DOI · Paper page
  8. Low JA, 1982, Am J Obstet Gynecol, 142, 670, 10.1016/S0002-9378(16)32439-5 · doi:10.1016/s0002-9378(16)32439-5
  9. Regev RH, 2003, J Pediatr, 143, 186, 10.1067/S0022-3476(03)00181-1 · DOI · Paper page
  10. Alkalay AL, 1998, J Perinatol, 18, 142
  11. Strauss RS, 1998, J Pediatr, 133, 67, 10.1016/S0022-3476(98)70180-5 · DOI
  12. Low JA, 1992, Am J Obstet Gynecol, 167, 1499, 10.1016/0002-9378(92)91727-R · DOI
  13. Sung IK, 1993, J Pediatr, 123, 618, 10.1016/S0022-3476(05)80965-5 · DOI · Paper page
  14. Nelson KG, 1997, Acta Obstet Gynecol Scand Suppl, 165, 87
  15. Gottleib S, 1988, Infant Behav Devel, 11, 223, 10.1016/S0163-6383(88)80007-9 · DOI
  16. Dietrich RB, 1988, Am J Roentgenol, 150, 889, 10.2214/ajr.150.4.889 · DOI · Paper page
  17. Mallard C, 2000, Neuroscience, 100, 327, 10.1016/S0306-4522(00)00271-2 · DOI · Paper page
  18. Mallard E, 1998, Pediatr Res, 43, 262, 10.1203/00006450-199802000-00018 · DOI · Paper page
  19. Cragg B, 1972, Brain, 95, 143, 10.1093/brain/95.1.143 · doi:10.1093/brain/95.1.143
  20. Winick M, 1969, Pediatr Res, 3, 181, 10.1203/00006450-196903000-00010 · DOI · Paper page
  21. Arbuckle TE, 1993, Obstet Gynecol, 81, 39
  22. Sonesson SE, 1993, J Clin Ultrasound, 21, 317, 10.1002/jcu.1870210505 · doi:10.1002/jcu.1870210505
  23. Hüppi PS, 1998, Ann Neurol, 43, 224, 10.1002/ana.410430213 · DOI · Paper page
  24. Inder TE, 1999, Ann Neurol, 46, 755, 10.1002/1531-8249(199911)46:5<755::AID-ANA11>3.0.CO;2-0 · doi:10.1002/1531-8249(199911)46:5<755::aid-ana11>3.0.co;2-0
  25. Warfield SK, 2000, Med Image Anal, 4, 43, 10.1016/S1361-8415(00)00003-7 · DOI · Paper page
  26. Buehler DM, 1995, Pediatrics, 96, 923, 10.1542/peds.96.5.923 · DOI
  27. O'Keeffe MJ, 2003, Pediatrics, 112, 301, 10.1542/peds.112.2.301 · DOI · Paper page
  28. Toft PB, 1995, Early Hum Dev, 43, 15, 10.1016/0378-3782(95)01657-O · DOI
  29. Owens JA, 1987, J Dev Physiol, 9, 137
  30. Regnault TR, 1999, J Endocrinol, 162, 433, 10.1677/joe.0.1620433 · DOI
  31. Rees S, 1999, J Neuropathol Exp Neurol, 58, 932, 10.1097/00005072-199909000-00004 · DOI
  32. Rees S, 1988, Int J Dev Neurosci, 6, 461, 10.1016/0736-5748(88)90052-4 · DOI
  33. Uno H, 1990, Brain Res Dev Brain Res, 53, 157, 10.1016/0165-3806(90)90002-G · DOI · Paper page
  34. Uno H, 1994, Horm Behav, 28, 336, 10.1006/hbeh.1994.1030 · DOI · Paper page
  35. Goland RS, 1993, J Clin Endocrinol Metab, 77, 1174, 10.1210/jc.77.5.1174 · DOI · Paper page
  36. Economides DL, 1991, J Perinat Med, 19, 97, 10.1515/jpme.1991.19.1-2.97 · DOI
  37. Modi N, 2001, Pediatr Res, 50, 581, 10.1203/00006450-200111000-00008 · DOI · Paper page
  38. Murphy BP, 2001, Pediatrics, 107, 217, 10.1542/peds.107.2.217 · DOI · Paper page
  39. Duncan JR, 2000, Am J Obstet Gynecol, 183, 1013, 10.1067/mob.2000.107321 · DOI
  40. Cianfarani S, 2002, Pediatr Res, 51, 94, 10.1203/00006450-200201000-00017 · DOI
  41. Frisk V, 2002, Dev Neuropsychol, 22, 565, 10.1207/S15326942DN2203_2 · DOI
  42. Hack M, 1991, N Engl J Med, 325, 231, 10.1056/NEJM199107253250403 · DOI · Paper page
  43. Als H, 1988, Infant Behav Dev, 11, 305, 10.1016/0163-6383(88)90016-1 · DOI
  44. Als H, 1994, JAMA, 272, 853, 10.1001/jama.1994.03520110033025 · doi:10.1001/jama.1994.03520110033025 · Paper page
  45. Hüppi PS, 1996, Pediatr Res, 39, 895, 10.1203/00006450-199605000-00026 · DOI · Paper page
  46. Peterson BS, 2000, JAMA, 284, 1939, 10.1001/jama.284.15.1939 · DOI · Paper page
  47. Peterson BS, 2003, Pediatrics, 111, 939, 10.1542/peds.111.5.939 · DOI · Paper page
  48. Isaacs EB, 2000, Pediatr Res, 47, 713, 10.1203/00006450-200006000-00006 · DOI · Paper page
  49. Scherjon S, 2000, Pediatrics, 105, 385, 10.1542/peds.105.2.385 · DOI · Paper page
  50. Ley D, 1996, Ultrasound Obstet Gynecol, 8, 152, 10.1046/j.1469-0705.1996.08030152.x · DOI
  51. Schreuder AM, 2002, Arch Dis Child Fetal Neonatal Ed, 86, F108, 10.1136/fn.86.2.F108 · DOI

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Metadata

Authors
Tolsa, C. B., Zimine, S., Warfield, S. K., Freschi, M., Rossignol, A. S., Lazeyras, F., Hanquinet, S., Pfizenmaier, M., & Hüppi, P. S.
Venue
Pediatric Research
Publisher
Springer Science and Business Media LLC
Published
2004-07
Volume
56
Issue
1
Pages
132-138
ISSN
  • 0031-3998 (ISSN-L)
  • 1530-0447
DOI
10.1203/01.pdr.0000128983.54614.7e
OpenAlex
W2170674178
Cited by
484
References
2
FWCI
11.32
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Early Alteration of Structural and Functional Brain Development in Premature Infants Born with Intrauterine Growth Restriction. https://app.cochat.ai/papers/10.1203/01.pdr.0000128983.54614.7e
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Tolsa, C. B., Zimine, S., Warfield, S. K., Freschi, M., Rossignol, A. S., Lazeyras, F., Hanquinet, S., Pfizenmaier, M., & Hüppi, P. S. (2004). Early Alteration of Structural and Functional Brain Development in Premature Infants Born with Intrauterine Growth Restriction. Pediatric Research. https://doi.org/10.1203/01.pdr.0000128983.54614.7e

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