Nutrition and brain development in early life

Prado, Elizabeth L; Dewey, Kathryn G

doi:10.1111/nure.12102

Cited by 1,036Child Nutrition and Water AccessBirth, Development, and HealthPublic Health and Nutrition

Nutrition and brain development in early life

Open access

Prado, Elizabeth L, Dewey, Kathryn G·2014·Nutrition Reviews

DOI 10.1111/nure.12102

Open this paper in CoChat — free account Open PDF

Abstract

Presented here is an overview of the pathway from early nutrient deficiency to long-term brain function, cognition, and productivity, focusing on research from low- and middle-income countries. Animal models have demonstrated the importance of adequate nutrition for the neurodevelopmental processes that occur rapidly during pregnancy and infancy, such as neuron proliferation and myelination. However, several factors influence whether nutrient deficiencies during this period cause permanent cognitive deficits in human populations, including the child's interaction with the environment, the timing and degree of nutrient deficiency, and the possibility of recovery. These factors should be taken into account in the design and interpretation of future research. Certain types of nutritional deficiency clearly impair brain development, including severe acute malnutrition, chronic undernutrition, iron deficiency, and iodine deficiency. While strategies such as salt iodization and micronutrient powders have been shown to improve these conditions, direct evidence of their impact on brain development is scarce. Other strategies also require further research, including supplementation with iron and other micronutrients, essential fatty acids, and fortified food supplements during pregnancy and infancy.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1111/nure.12102

Cites

203 of 203 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Deficits of key micronutrients early in life can lead to impairments in the central nervous system, and vitamin B-12 may be one such critical micronutrient.
“Deficits of key micronutrients early in life can lead to impairments in the central nervous system (2,3), and vitamin B-12 (cobalamin) may be one such critical micronutrient (4,5).”
From Vitamin B-12 status in infancy is positively associated with development and cognitive functioning 5 y later in Nepalese children (2017) · cites this paper as [2]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Part of this paper’s reference list could not be split into single entries.

Maternal and child undernutrition and overweight in low-income and middle-income countries
Black, R. E., Victora, C. G., Walker, S. P., Bhutta, Z. A., Christian, P., de Onis, M., Ezzati, M., Grantham-McGregor, S., Katz, J., Martorell, R., et al. (2013) · The Lancet · doi:10.1016/s0140-6736(13)60937-x · Cited by 8,475 · see citing works
Bayley Scales of Infant Development
(2007) · Encyclopedia of Measurement and Statistics · doi:10.4135/9781412952644.n48 · Cited by 4,242 · see citing works
Untitled work
(1998) · Cited by 4,172 · see citing works
Peabody Picture Vocabulary Test
Campbell, J. M., & Dommestrup, A. K. (2010) · The Corsini Encyclopedia of Psychology · doi:10.1002/9780470479216.corpsy0649 · Cited by 3,787 · see citing works
Developmental potential in the first 5 years for children in developing countries
Grantham-McGregor, S., Cheung, Y. B., Cueto, S., Glewwe, P., Richter, L., & Strupp, B. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60032-4 · Cited by 3,630 · see citing works
Navigation-related structural change in the hippocampi of taxi drivers
Maguire, E. A., Gadian, D. G., Johnsrude, I. S., Good, C. D., Ashburner, J., Frackowiak, R. S. J., & Frith, C. D. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.070039597 · Cited by 3,225 · see citing works
Cell death during development of the nervous system
Oppenheim, R. W. (1991) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.14.030191.002321 · Cited by 3,084 · see citing works
Child development: risk factors for adverse outcomes in developing countries
Walker, S. P., Wachs, T. D., Meeks Gardner, J., Lozoff, B., Wasserman, G. A., Pollitt, E., & Carter, J. A. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60076-2 · Cited by 2,133 · see citing works
Neuropsychological assessment, 4th ed.
Lezak, M. D., Howieson, D. B., Loring, D. W., Hannay, H. J., & Fischer, J. S. (2004) · Cited by 1,934 · see citing works
Inequality in early childhood: risk and protective factors for early child development
Walker, S. P., Wachs, T. D., Grantham-McGregor, S., Black, M. M., Nelson, C. A., Huffman, S. L., Baker-Henningham, H., Chang, S. M., Hamadani, J. D., Lozoff, B., et al. (2011) · The Lancet · doi:10.1016/s0140-6736(11)60555-2 · Cited by 1,756 · see citing works
Worldwide prevalence of anaemia 1993-2005: WHO global database on anaemia.
de Benoist, B., McLean, E., Egll, I., & Cogswell, M. E. (2008) · Cited by 1,543 · see citing works
Breastfeeding and Maternal and Infant Health Outcomes In Developed Countries
(2007) · AAP Grand Rounds · doi:10.1542/gr.18-2-15 · Cited by 1,540 · see citing works
The Child Behavior Checklist and Related Forms for Assessing Behavioral/Emotional Problems and Competencies
Achenbach, T. M., & Ruffle, T. M. (2000) · Pediatrics in Review · doi:10.1542/pir.21-8-265 · Cited by 1,287 · see citing works
Breast-feeding and cognitive development: a meta-analysis
Anderson, J. W., Johnstone, B. M., & Remley, D. T. (1999) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/70.4.525 · Cited by 1,276 · see citing works
Extensive piano practicing has regionally specific effects on white matter development
Bengtsson, S. L., Nagy, Z., Skare, S., Forsman, L., Forssberg, H., & Ullén, F. (2005) · Nature Neuroscience · doi:10.1038/nn1516 · Cited by 1,193 · see citing works
Handbook of Developmental Cognitive Neuroscience
(2008) · The MIT Press eBooks · doi:10.7551/mitpress/7437.001.0001 · Cited by 1,188 · see citing works
International Zinc Nutrition Consultative Group (IZiNCG) technical document #1. Assessment of the risk of zinc deficiency in populations and options for its control.
Brown, K. H., Rivera, J. A., Bhutta, Z. A., Gibson, R. S., King, J. C., Lönnerdal, B. L., Ruel, M. T., Sandtröm, B., Wasantwisut, E., & Hotz, C. (2004) · PubMed · Cited by 1,069 · see citing works
Oligosaccharides in Human Milk: Structural, Functional, and Metabolic Aspects
Kunz, C., Rudloff, S., Baier, W., Klein, N. J., & Ströbel, S. (2000) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.20.1.699 · Cited by 1,037 · see citing works
Breastfeeding and Child Cognitive Development: New Evidence From a Large Randomized Trial
Kramer, M. S. (2008) · Archives of General Psychiatry · doi:10.1001/archpsyc.65.5.578 · Cited by 1,016 · see citing works
Strategies for reducing inequalities and improving developmental outcomes for young children in low-income and middle-income countries
Engle, P. L., Fernald, L. C., Alderman, H., Behrman, J., O'Gara, C., Yousafzai, A., de Mello, M. C., Hidrobo, M., Ulkuer, N., Ertem, I., et al. (2011) · The Lancet · doi:10.1016/s0140-6736(11)60889-1 · Cited by 995 · see citing works
Functional brain development in humans
Johnson, M. H. (2001) · Nature Reviews Neuroscience · doi:10.1038/35081509 · Cited by 980 · see citing works
Long-lasting neural and behavioral effects of iron deficiency in infancy
Lozoff, B., Beard, J., Connor, J., Felt, B., Georgieff, M., & Schallert, T. (2006) · Nutrition Reviews · doi:10.1301/nr.2006.may.s34-s43 · Cited by 975 · see citing works
Systematic review of the efficacy and effectiveness of complementary feeding interventions in developing countries
Dewey, K. G., & Adu‐Afarwuah, S. (2008) · Maternal and Child Nutrition · doi:10.1111/j.1740-8709.2007.00124.x · Cited by 950 · see citing works
Self-citation
Nutrition and the developing brain: nutrient priorities and measurement
Georgieff, M. (2007) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/85.2.614s · Cited by 885 · see citing works
Handbook of developmental cognitive neuroscience
O’Connor, T. G. (2002) · Attachment & Human Development · Cited by 873 · see citing works
Effect of a nutrition intervention during early childhood on economic productivity in Guatemalan adults
Hoddinott, J. F., Maluccio, J. A., Behrman, J. R., Flores, R., & Martorell, R. (2008) · The Lancet · doi:10.1016/s0140-6736(08)60205-6 · Cited by 867 · see citing works
Modeling transformations of neurodevelopmental sequences across mammalian species
Workman, A. D., Charvet, C. J., Clancy, B., Darlington, R. B., & Finlay, B. L. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.5746-12.2013 · Cited by 833 · see citing works
BRAIN PLASTICITY AND BEHAVIOR
Kolb, B. E., & Whishaw, I. Q. (1998) · Annual Review of Psychology · doi:10.1146/annurev.psych.49.1.43 · Cited by 781 · see citing works
Effect of inadequate iodine status in UK pregnant women on cognitive outcomes in their children: results from the Avon Longitudinal Study of Parents and Children (ALSPAC)
Bath, S. C., Steer, C. D., Golding, J., Emmett, P. M., & Rayman, M. P. (2013) · The Lancet · doi:10.1016/s0140-6736(13)60436-5 · Cited by 733 · see citing works
Nutritional supplementation, psychosocial stimulation, and mental development of stunted children: the Jamaican Study
Grantham-McGregor, S. M., Powell, C. A., Walker, S. P., & Himes, J. H. (1991) · The Lancet · doi:10.1016/0140-6736(91)90001-6 · Cited by 685 · see citing works
I <scp>RON</scp> S <scp>TATUS AND</scp> N <scp>EURAL</scp> F <scp>UNCTIONING</scp>
Beard, J. L., & Connor, J. R. (2003) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.23.020102.075739 · Cited by 669 · see citing works
Famine and Human Development. The Dutch Hunger Winter of 1944-1945.
(1975) · Annals of Internal Medicine · doi:10.7326/0003-4819-83-2-290_1 · Cited by 658 · see citing works
ASSESSMENT OF THE RISK OF DEFICIENCY IN POPULATIONS AND OPTIONS FOR ITS CONTROL
Hotz, C. S., & Brown, K. M. (2004) · Cited by 654 · see citing works
Acquiring “the Knowledge” of London's Layout Drives Structural Brain Changes
Woollett, K., & Maguire, E. A. (2011) · Current Biology · doi:10.1016/j.cub.2011.11.018 · Cited by 509 · see citing works
Thyroid Hormones and Brain Development
Dussault, J. H., & Ruel, J. (1987) · Annual Review of Physiology · doi:10.1146/annurev.ph.49.030187.001541 · Cited by 500 · see citing works
You can't take it with you: Why ability assessments don't cross cultures.
Greenfield, P. M. (1997) · American Psychologist · doi:10.1037/0003-066x.52.10.1115 · Cited by 495 · see citing works
Early Alteration of Structural and Functional Brain Development in Premature Infants Born with Intrauterine Growth Restriction
Tolsa, C. B., Zimine, S., Warfield, S. K., Freschi, M., Rossignol, A. S., Lazeyras, F., Hanquinet, S., Rousseil, M. P., & Hüppi, P. S. (2004) · Pediatric Research · doi:10.1203/01.pdr.0000128983.54614.7e · Cited by 483 · see citing works
Effects of early childhood psychosocial stimulation and nutritional supplementation on cognition and education in growth-stunted Jamaican children: prospective cohort study
Walker, S. P., Chang, S. M., Powell, C. A., & Grantham‐McGregor, S. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67574-5 · Cited by 480 · see citing works
NEUROLOGICAL DAMAGE TO THE FETUS RESULTING FROM SEVERE IODINE DEFICIENCY DURING PREGNANCY
Pharoah, P. O. D., Buttfield, I. H., & Hetzel, B. S. (1971) · The Lancet · doi:10.1016/s0140-6736(71)91040-3 · Cited by 469 · see citing works
B vitamins, homocysteine, and neurocognitive function in the elderly
Selhub, J., Bagley, L. C., Miller, J. W., & Rosenberg, I. H. (2000) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/71.2.614s · Cited by 462 · see citing works
Abnormal brain connectivity in children after early severe socioemotional deprivation: A diffusion tensor imaging study
Eluvathingal, T. J., Chugani, H. T., Behen, M. E., Juhász, C., Muzik, O., Maqbool, M., Chugani, D. C., & Makki, M. (2006) · Pediatrics · doi:10.1542/peds.2005-1727 · Cited by 451 · see citing works
Effect of breast feeding on intelligence in children: prospective study, sibling pairs analysis, and meta-analysis
Der, G., Batty, G. D., & Deary, I. J. (2006) · BMJ · doi:10.1136/bmj.38978.699583.55 · Cited by 451 · see citing works
Continuity in Mental Development from Infancy
Bornstein, M. H., & Sigman, M. (1986) · Child Development · doi:10.1111/j.1467-8624.1986.tb00025.x · Cited by 441 · see citing works
Zinc: Health Effects and Research Priorities for the 1990s
Walsh, C. T., Sandstead, H. H., Prasad, A. S., Newberne, P. M., & Fraker, P. J. (1994) · Environmental Health Perspectives · doi:10.1289/ehp.941025 · Cited by 435 · see citing works
Prenatal Exposure to Wartime Famine and Development of Antisocial Personality Disorder in Early Adulthood
Neugebauer, R. (1999) · JAMA · doi:10.1001/jama.282.5.455 · Cited by 432 · see citing works
Iodine Deficiency in 2007: Global Progress since 2003
de Benoist, B., McLean, E., Andersson, M., & Rogers, L. (2008) · Food and Nutrition Bulletin · doi:10.1177/156482650802900305 · Cited by 425 · see citing works
Nutrition in Brain Development and Aging: Role of Essential Fatty Acids
Uauy, R. D., & Dangour, A. D. (2006) · Nutrition Reviews · doi:10.1301/nr.2006.may.s24-s33 · Cited by 417 · see citing works
A Review of Studies of the Effect of Severe Malnutrition on Mental Development
Grantham‐McGregor, S. (1995) · Journal of Nutrition · doi:10.1093/jn/125.suppl_8.2233s · Cited by 410 · see citing works
Double Burden of Iron Deficiency in Infancy and Low Socioeconomic Status
Lozoff, B., Jiménez, E., & Smith, J. B. (2006) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.160.11.1108 · Cited by 392 · see citing works
What are the causal effects of breastfeeding on IQ, obesity and blood pressure? Evidence from comparing high-income with middle-income cohorts
Brion, M.-J. A., Lawlor, D. A., Matijasevich, A., Horta, B., Anselmi, L., Araújo, C. L., Menezes, A. M. B., Victora, C. G., & Smith, G. D. (2011) · International Journal of Epidemiology · doi:10.1093/ije/dyr020 · Cited by 350 · see citing works
Randomized comparison of 3 types of micronutrient supplements for home fortification of complementary foods in Ghana: effects on growth and motor development
Adu‐Afarwuah, S., Lartey, A. A., Brown, K. H., Zlotkin, S. H., Briend, A., & Dewey, K. G. (2007) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/86.2.412 · Cited by 329 · see citing works
Self-citation
Iodine deficiency and brain development in the first half of pregnancy
de Escobar, G. M., Obregón, M.-J., & del Rey, F. E. (2007) · Public Health Nutrition · doi:10.1017/s1368980007360928 · Cited by 321 · see citing works
Early Childhood Stunting Is Associated with Poor Psychological Functioning in Late Adolescence and Effects Are Reduced by Psychosocial Stimulation
Walker, S. P., Chang, S. M., Powell, C. A., Simonoff, E. A., & Grantham‐McGregor, S. (2007) · Journal of Nutrition · doi:10.1093/jn/137.11.2464 · Cited by 311 · see citing works
Preventive Zinc Supplementation among Infants, Preschoolers, and Older Prepubertal Children
Brown, K. H., Peerson, J. M., Baker, S. K., & Hess, S. Y. (2009) · Food and Nutrition Bulletin · doi:10.1177/15648265090301s103 · Cited by 309 · see citing works
Zinc deficiency and child development
Black, M. M. (1998) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/68.2.464s · Cited by 306 · see citing works
Maternal Vitamin B12 Status and Risk of Neural Tube Defects in a Population With High Neural Tube Defect Prevalence and No Folic Acid Fortification
Molloy, A. M., Kirke, P. N., Troendle, J. F., Burke, H. M., Sutton, M., Brody, L. C., Scott, J. M., & Mills, J. L. (2009) · PEDIATRICS · doi:10.1542/peds.2008-1173 · Cited by 306 · see citing works
The Effect of Severe Early Malnutrition on Cellular Growth of Human Brain
Winick, M., & Rosso, P. (1969) · Pediatric Research · doi:10.1203/00006450-196903000-00010 · Cited by 304 · see citing works
Early Supplementary Feeding and Cognition: Effects over Two Decades
Pollitt, E., Gorman, K. S., Engle, P. L., Martorell, R., Rivera, J. Á., Wachs, T. D., & Scrimshaw, N. S. (1993) · Monographs of the Society for Research in Child Development · doi:10.2307/1166162 · Cited by 304 · see citing works
A quantitative dendritic analysis of wernicke's area in humans. II. Gender, hemispheric, and environmental factors
Jacobs, B., Schall, M., & Scheibel, A. B. (1993) · The Journal of Comparative Neurology · doi:10.1002/cne.903270108 · Cited by 302 · see citing works
SHEEP MODELS OF INTRAUTERINE GROWTH RESTRICTION: FETAL ADAPTATIONS AND CONSEQUENCES
Morrison, J. L. (2008) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2008.04975.x · Cited by 289 · see citing works
Differential rearing affects corpus callosum size and cognitive function of rhesus monkeys
Sánchez, M. M., Hearn, E. F., Do, D., Rilling, J. K., & Herndon, J. G. (1998) · Brain Research · doi:10.1016/s0006-8993(98)00857-9 · Cited by 282 · see citing works
Effects of early childhood supplementation with and without stimulation on later development in stunted Jamaican children
Grantham‐McGregor, S., Walker, S., Chang, S., & Powell, C. (1997) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/66.2.247 · Cited by 276 · see citing works
Behavior of Infants with Iron-Deficiency Anemia
Lozoff, B., Klein, N. K., Nelson, E. C., McClish, D. K., Manuel, M., & Chacon, M. E. (1998) · Child Development · doi:10.1111/j.1467-8624.1998.tb06130.x · Cited by 263 · see citing works
Prenatal Micronutrient Supplementation and Intellectual and Motor Function in Early School-aged Children in Nepal
Christian, P. S. (2010) · JAMA · doi:10.1001/jama.2010.1861 · Cited by 263 · see citing works
Iron and zinc supplementation promote motor development and exploratory behavior among Bangladeshi infants
Black, M. M., Baqui, A. H., Zaman, K., Ake Persson, L., El Arifeen, S., Le, K., McNary, S. W., Parveen, M., Hamadani, J. D., & Black, R. E. (2004) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/80.4.903 · Cited by 256 · see citing works
Malnutrition and Environmental Enrichment by Early Adoption
Winick, M., Meyer, K. K., & Harris, R. C. (1975) · Science · doi:10.1126/science.1198103 · Cited by 249 · see citing works
Induction of brain structure by experience: Substrates for cognitive development.
Greenough, W. T., & Black, J. (1992) · Cited by 248 · see citing works
Nutritional and Environmental Interactions in the Behavioral Development of the Rat: Long-Term Effects
Levitsky, D. A., & Barnes, R. H. (1972) · Science · doi:10.1126/science.176.4030.68 · Cited by 246 · see citing works
The effects of iodine on intelligence in children: a meta-analysis of studies conducted in China.
Qian, M., Wang, D., We, W., Gebski, V., Yq, Y., Li, M., & Zp, C. (2005) · PubMed · Cited by 246 · see citing works
Guidelines for the Inpatient Treatment of Severely Malnourished Children
Ashworth, A., Khanum, S., Jackson, A. A., et al. (2004) · LSHTM Research Online (London School of Hygiene and Tropical Medicine) · Cited by 243 · see citing works
Human milk and formula fatty acids
Innis, S. M. (1992) · The Journal of Pediatrics · doi:10.1016/s0022-3476(05)81237-5 · Cited by 238 · see citing works
Issues in the timing of integrated early interventions: contributions from nutrition, neuroscience, and psychological research
Wachs, T. D., Georgieff, M., Cusick, S. E., & McEwen, B. S. (2013) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12314 · Cited by 236 · see citing works
How Good Is the Evidence Linking Breastfeeding and Intelligence?
Jain, A., Concato, J., & Leventhal, J. M. (2002) · PEDIATRICS · doi:10.1542/peds.109.6.1044 · Cited by 233 · see citing works
The Damaged Brain of Iodine Deficiency
Dodge, P. R. (1996) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/63.4.615-a · Cited by 231 · see citing works
Neurodevelopmental Disorders after Prenatal Famine: The Story of the Dutch Famine Study
Susser, E., Hoek, H. W., & Brown, A. (1998) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009439 · Cited by 230 · see citing works
Developmental Zinc Deficiency and Behavior
Golub, M. S., Keen, C. L., Gershwin, M. E., & Hendrickx, A. G. (1995) · Journal of Nutrition · doi:10.1093/jn/125.suppl_8.2263s · Cited by 224 · see citing works
The effect of maternal omega-3 (n-3) LCPUFA supplementation during pregnancy on early childhood cognitive and visual development: a systematic review and meta-analysis of randomized controlled trials
Gould, J. F., Smithers, L. G., & Makrides, M. (2013) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.045781 · Cited by 221 · see citing works
Effects of growth restriction in early childhood on growth, IQ, and cognition at age 11 to 12 years and the benefits of nutritional supplementation and psychosocial stimulation
Walker, S. P., Grantham-McGregor, S. M., Powell, C. A., & Chang, S. M. (2000) · The Journal of Pediatrics · doi:10.1067/mpd.2000.106227 · Cited by 218 · see citing works
Prenatal Exposure to Famine and Brain Morphology in Schizophrenia
Pol, H. E. H., Hoek, H. W., Susser, E., Brown, A. S., Dingemans, A. E., Schnack, H. G., van Haren, N. E. M., Ramos, L. M. P., Wied, C. C. G., & Kahn, R. S. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.7.1170 · Cited by 215 · see citing works
History of Zinc as Related to Brain Function
Sandstead, H. H., Frederickson, C. J., & Penland, J. G. (2000) · Journal of Nutrition · doi:10.1093/jn/130.2.496s · Cited by 214 · see citing works
Maternal Dietary (n-3) Fatty Acid Deficiency Alters Neurogenesis in the Embryonic Rat Brain
Bertrand, P. C., OʼKusky, J. R., & Innis, S. M. (2006) · Journal of Nutrition · doi:10.1093/jn/136.6.1570 · Cited by 214 · see citing works
Perinatal iron deficiency alters apical dendritic growth in hippocampal CA1 pyramidal neurons
Jorgenson, L. A., Wobken, J. D., & Georgieff, M. K. (2003) · Developmental Neuroscience · doi:10.1159/000075667 · Cited by 209 · see citing works
Sex and environmental influences on the size and ultrastructure of the rat corpus callosum
Juraska, J. M., & Kopcik, J. R. (1988) · Brain Research · doi:10.1016/0006-8993(88)91538-7 · Cited by 208 · see citing works
Growth and development of term children born with low birth weight: Effects of genetic and environmental factors
Strauss, R. S., & Dietz, W. H. (1998) · The Journal of Pediatrics · doi:10.1016/s0022-3476(98)70180-5 · Cited by 205 · see citing works
Iodine and Mental Development of Children 5 Years Old and Under: A Systematic Review and Meta-Analysis
Bougma, K., Aboud, F. E., Harding, K., & Marquis, G. S. (2013) · Nutrients · doi:10.3390/nu5041384 · Cited by 202 · see citing works
A community-based randomized controlled trial of iron and zinc supplementation in Indonesian infants: effects on growth and development
Lind, T., Lönnerdal, B. L., Stenlund, H. C., Gamayanti, I. L., Ismail, D., Seswandhana, R., & Persson, L. Å. (2004) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/80.3.729 · Cited by 200 · see citing works
Zinc Supplementation in Very-Low-Birth-Weight Infants
Friel, J. K., Andrews, W. L., Matthew, J. D., et al. (1993) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/00005176-199307000-00015 · Cited by 197 · see citing works
Effects of prenatal food and micronutrient supplementation on infant development: a randomized trial from the Maternal and Infant Nutrition Interventions, Matlab (MINIMat) study
Tofail, F., Persson, L. Å., Arifeen, S. E., Hamadani, J. D., Mehrin, F., Ridout, D. A., Ekström, E.-C., Huda, S. N., & Grantham‐McGregor, S. (2008) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/87.3.704 · Cited by 196 · see citing works
Long-term effects of LCPUFA supplementation on childhood cognitive outcomes
Colombo, J. A., Carlson, S. E., Cheatham, C. L., Shaddy, D. J., Kerling, E. H., Thodosoff, J. M., Gustafson, K. M., & Brez, C. C. (2013) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.040766 · Cited by 194 · see citing works
Nutritional supplementation, maternal education, and cognitive development of infants at risk of malnutrition
Waber, D. P., Vuori-Christiansen, L., Ortíz, N., Clement, J. R., Christiansen, N., Mora, J. O., Reed, R. B., & Herrera, M. G. (1981) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/34.4.807 · Cited by 186 · see citing works
Time course of axonal myelination in the human brainstem auditory pathway
Moore, J. K., Perazzo, L. M., & Braun, A. (1995) · Hearing Research · doi:10.1016/0378-5955(95)00073-d · Cited by 184 · see citing works
Children Who Recover from Early Stunting and Children Who Are Not Stunted Demonstrate Similar Levels of Cognition
Crookston, B. T., Penny, M. E., Alder, S. C., Dickerson, T., Merrill, R. M., Stanford, J. B., Porucznik, C. A., & Dearden, K. A. (2010) · Journal of Nutrition · doi:10.3945/jn.109.118927 · Cited by 181 · see citing works
Human Nutrition-A Comprehensive Treatise
Chandrasekhar, U. (1984) · The Indian Journal of Nutrition and Dietetics · Cited by 173 · see citing works
A Neurobiological Perspective on Early Human Deprivation
Nelson, C. A. (2007) · Child Development Perspectives · doi:10.1111/j.1750-8606.2007.00004.x · Cited by 168 · see citing works
Iodine deficiency in pregnancy, infancy and childhood and its consequences for brain development
Melse‐Boonstra, A., & Jaiswal, N. (2010) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2009.09.002 · Cited by 166 · see citing works
Recent Evidence from Human and Animal Studies Regarding Iron Status and Infant Development
Beard, J. (2007) · Journal of Nutrition · doi:10.1093/jn/137.2.524s · Cited by 164 · see citing works
Fetal iron deficiency disrupts the maturation of synaptic function and efficacy in area CA1 of the developing rat hippocampus
Jorgenson, L. A., Sun, M., O'Connor, M., & Georgieff, M. K. (2005) · Hippocampus · doi:10.1002/hipo.20128 · Cited by 162 · see citing works
Choline: Needed for Normal Development of Memory
Zeisel, S. H. (2000) · Journal of the American College of Nutrition · doi:10.1080/07315724.2000.10718976 · Cited by 162 · see citing works
Zinc Supplementation Affects the Activity Patterns of Rural Guatemalan Infants , ,
Bentley, M. E., Caulfield, L. E., Ram, M., et al. (1997) · Journal of Nutrition · doi:10.1093/jn/127.7.1333 · Cited by 162 · see citing works
Chronic marginal iron intakes during early development in mice result in persistent changes in dopamine metabolism and myelin composition
Kwik-Uribe, C. L., Gietzen, D., German, J. B., Golub, M. S., & Keen, C. L. (2000) · The Journal of Nutrition · doi:10.1093/jn/130.11.2821 · Cited by 156 · see citing works
A metaanalysis of research on iodine and its relationship to cognitive development.
Bleichrodt, N., & Born, M. P. (1996) · VU Research Portal · Cited by 154 · see citing works
Essential fats: how do they affect growth and development of infants and young children in developing countries? A literature review
Huffman, S. L., Harika, R. K., Eilander, A., & Osendarp, S. J. M. (2011) · Maternal and Child Nutrition · doi:10.1111/j.1740-8709.2011.00356.x · Cited by 154 · see citing works
Famine and Human Development: The Dutch Hunger Winter 1944-1945
Smith, C. A. (1976) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.1976.02120030112028 · Cited by 153 · see citing works
Risks of Iodine-Induced Hyperthyroidism After Correction of Iodine Deficiency by Iodized Salt*
Delange, F. M., de Benoist, B., & Alnwick, D. J. (1999) · Thyroid · doi:10.1089/thy.1999.9.545 · Cited by 153 · see citing works
A critical evaluation of the evidence on the association between type of infant feeding and cognitive development
Drane, D. L., & Logemann, J. A. (2000) · Paediatric and Perinatal Epidemiology · doi:10.1046/j.1365-3016.2000.00301.x · Cited by 152 · see citing works
Effect of a fortified maize-meal porridge on anemia, micronutrient status, and motor development of infants
Faber, M., Kvalsvig, J. D., Lombard, C. J., & Benadé, A. (2005) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/82.5.1032 · Cited by 150 · see citing works
Vulnerability of the fetal primate brain to moderate reduction in maternal global nutrient availability
Antonow‐Schlorke, I., Schwab, M. G., Cox, L. A., Li, C., Stuchlik, K. M., Witte, O. W., Nathanielsz, P. W., & McDonald, T. J. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1009838108 · Cited by 143 · see citing works
Relation of maternal zinc nutriture to pregnancy outcome and infant development in an Egyptian village
Kirksey, A., Wachs, T., Yunis, F. A., Srinath, U., Rahmanifar, A., McCabe, G. P., Galal, O., Harrison, G. G., & Jerome, N. (1994) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/60.5.782 · Cited by 142 · see citing works
Infant Malnutrition Is Associated with Persisting Attention Deficits in Middle Adulthood
Galler, J. R., Bryce, C. P., Zichlin, M. L., Fitzmaurice, G. M., Eaglesfield, G. D., & Waber, D. P. (2012) · Journal of Nutrition · doi:10.3945/jn.111.145441 · Cited by 141 · see citing works
Maternal iron status influences iron transfer to the fetus during the third trimester of pregnancy
O’Brien, K. O., Zavaleta, N., Abrams, S. A., & Caulfield, L. E. (2003) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/77.4.924 · Cited by 140 · see citing works
Undernutrition and the development of brain neurotransmitter systems
Wiggins, R. C., Fuller, G. N., & Enna, S. J. (1984) · Life Sciences · doi:10.1016/0024-3205(84)90507-1 · Cited by 139 · see citing works
Review of the evidence linking protein and energy to mental development
Grantham‐McGregor, S., & Baker‐Henningham, H. (2005) · Public Health Nutrition · doi:10.1079/phn2005805 · Cited by 138 · see citing works
Zinc supplementation during pregnancy and effects on mental development and behaviour of infants: a follow-up study
Hamadani, J. D., Fuchs, G. J., Osendarp, S. J. M., Huda, S. N., & Grantham‐McGregor, S. (2002) · The Lancet · doi:10.1016/s0140-6736(02)09551-x · Cited by 138 · see citing works
Effect of Zinc Supplementation on Observed Activity in Low Socioeconomic Indian Preschool Children
Sazawal, S., Bentley, M. E., Black, R. E., et al. (1996) · PEDIATRICS · doi:10.1542/peds.98.6.1132 · Cited by 135 · see citing works
Developmental behavioral neuroscience
Gunnar, M. R., & Nelson, C. A. (1992) · Medical Entomology and Zoology · Cited by 132 · see citing works
Zinc supplementation and psychosocial stimulation: effects on the development of undernourished Jamaican children
Gardner, J. M., Powell, C. A., Baker‐Henningham, H., Walker, S. P., Cole, T. J., & Grantham‐McGregor, S. (2005) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/82.2.399 · Cited by 132 · see citing works
Breast milk and cognitive development—the role of confounders: a systematic review
Walfisch, A., Sermer, C., Cressman, A. M., & Koren, G. (2013) · BMJ Open · doi:10.1136/bmjopen-2013-003259 · Cited by 130 · see citing works
Session 4: Mineral metabolism and body composition Iron status of breast-fed infants
Dewey, K. G., & Chaparro, C. M. (2007) · Proceedings of The Nutrition Society · doi:10.1017/s002966510700568x · Cited by 127 · see citing works
Self-citation
Iron-Fortified vs Low-Iron Infant Formula
Lozoff, B. (2011) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpediatrics.2011.197 · Cited by 127 · see citing works
Breastfeeding and Brain Development
Reynolds, A. (2001) · Pediatric Clinics of North America · doi:10.1016/s0031-3955(05)70291-1 · Cited by 127 · see citing works
Thiamin deficiency and brain disorders
Butterworth, R. F. (2003) · Nutrition Research Reviews · doi:10.1079/nrr200367 · Cited by 126 · see citing works
Iron deficiency and iron-deficiency anemia in the first two years of life: strategies to prevent loss of developmental potential
Black, M. M., Quigg, A. M., Hurley, K. M., & Pepper, M. R. (2011) · Nutrition Reviews · doi:10.1111/j.1753-4887.2011.00435.x · Cited by 123 · see citing works
The Fagan test of infant intelligence: A technical summary
Fagan, J. F., & Detterman, D. K. (1992) · Journal of Applied Developmental Psychology · doi:10.1016/0193-3973(92)90028-g · Cited by 119 · see citing works
Breast-Feeding Influences Cognitive Development in Filipino Children
Daniels, M. C., & Adair, L. S. (2005) · Journal of Nutrition · doi:10.1093/jn/135.11.2589 · Cited by 119 · see citing works
Randomized controlled trial of the effect of zinc supplementation on the mental development of Bangladeshi infants
Hamadani, J. D., Fuchs, G. J., Osendarp, S. J. M., Khatun, F., Huda, S. N., & Grantham‐McGregor, S. (2001) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/74.3.381 · Cited by 118 · see citing works
Effect of iron supplementation during pregnancy on the intelligence quotient and behavior of children at 4 y of age: long-term follow-up of a randomized controlled trial
Zhou, S. J., Gibson, R. A., Crowther, C. A., Baghurst, P., & Makrides, M. (2006) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/83.5.1112 · Cited by 118 · see citing works
Prenatal choline availability modulates hippocampal neurogenesis and neurogenic responses to enriching experiences in adult female rats
Glenn, M. J., Gibson, E. M., Kirby, E. D., Mellott, T. J., Blusztajn, J. K., & Williams, C. L. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05505.x · Cited by 116 · see citing works
Meta-analysis of Long-Chain Polyunsaturated Fatty Acid Supplementation of Formula and Infant Cognition
Qawasmi, A., Landeros‐Weisenberger, A., Leckman, J. F., & Bloch, M. H. (2012) · PEDIATRICS · doi:10.1542/peds.2011-2127 · Cited by 114 · see citing works
Effects of Maternal Multimicronutrient Supplementation on the Mental Development of Infants in Rural Western China: Follow-up Evaluation of a Double-Blind, Randomized, Controlled Trial
Li, Q., Yan, H., Zeng, L., Cheng, Y., Liang, W., Dang, S., Wang, Q., & Tsuji, I. (2009) · PEDIATRICS · doi:10.1542/peds.2008-3007 · Cited by 112 · see citing works
Nutrition and cognition: assessing cognitive abilities in children and young people
Isaacs, E., Oates, J., & a.i.s.b.l., I. E. (2008) · European Journal of Nutrition · doi:10.1007/s00394-008-3002-y · Cited by 112 · see citing works
Prenatal exposure to the 1944–45 Dutch ‘hunger winter’ and addiction later in life
Franzek, E., Sprangers, N., Janssens, A. C. J. W., van Duijn, C. M., & van de Wetering, B. J. M. (2008) · Addiction · doi:10.1111/j.1360-0443.2007.02084.x · Cited by 111 · see citing works
The effect of birthweight on childhood cognitive development in a middle-income country
Torche, F., & Echevarría, G. C. (2011) · International Journal of Epidemiology · doi:10.1093/ije/dyr030 · Cited by 109 · see citing works
The Impaired Growth Induced by Zinc Deficiency in Rats Is Associated with Decreased Expression of the Hepatic Insulin-like Growth Factor I and Growth Hormone Receptor Genes
McNall, A. D., Etherton, T. D., & Fosmire, G. J. (1995) · Journal of Nutrition · doi:10.1093/jn/125.4.874 · Cited by 109 · see citing works
Cobalamin and folate status predicts mental development scores in North Indian children 12–18 mo of age
Strand, T. A., Taneja, S., Ueland, P. M., Refsum, H., Bahl, R., Schneede, J., Sommerfelt, H., & Bhandari, N. (2013) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.111.032268 · Cited by 108 · see citing works
Neurodevelopmental Outcome in Children With Intrauterine Growth Retardation: A 3-Year Follow-Up
Fattal‐Valevski, A., Leitner, Y., Kutai, M., Tal-Posener, E., Tomer, A., Lieberman, D., Jaffa, A. J., Many, A., & Harel, S. (1999) · Journal of Child Neurology · doi:10.1177/088307389901401107 · Cited by 107 · see citing works
Long-chain PUFA supplementation in rural African infants: a randomized controlled trial of effects on gut integrity, growth, and cognitive development
van der Merwe, L. F., Moore, S. E., Fulford, A. J. C., Halliday, K. E., Drammeh, S., Young, S., & Prentice, A. M. (2012) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.042267 · Cited by 107 · see citing works
Developmental effects of short-term supplementary feeding in nutritionally-at-risk Indonesian infants
Husaini, M., Karyadi, L., Husaini, Y. K., Sandjaja, Karyadi, D., & Pollitt, E. (1991) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/54.5.799 · Cited by 106 · see citing works
FETAL IODINE DEFICIENCY AND MOTOR PERFORMANCE DURING CHILDHOOD
Connolly, K., Pharoah, P. D., & Hetzel, B. (1979) · The Lancet · doi:10.1016/s0140-6736(79)92382-1 · Cited by 106 · see citing works
Effect of zinc supplementation on development and growth of Chilean infants
Castillo‐Durán, C., Perales, C. G., Hertrampf, E., Marín, V. B., Rivera, F., & Icaza, G. (2001) · The Journal of Pediatrics · doi:10.1067/mpd.2001.110530 · Cited by 103 · see citing works
Zinc: Essentiality for Brain Development and Function
Sandstead, H. H. (2009) · Nutrition Reviews · doi:10.1111/j.1753-4887.1985.tb06889.x · Cited by 98 · see citing works
Famine and Human Development: The Dutch Hunger Winter of 1944/45.
Richardson, S. A., Stein, Z., Susser, M. W., Saenger, G., & MAROLLA, F. A. (1976) · Contemporary Sociology A Journal of Reviews · doi:10.2307/2063418 · Cited by 97 · see citing works
Early Childhood Development Interventions and Cognitive Development of Young Children in Rural Vietnam
Watanabe, K., Flores, R., Fujiwara, J., & Tran, L. T. H. (2005) · Journal of Nutrition · doi:10.1093/jn/135.8.1918 · Cited by 95 · see citing works
Early malnutrition and “late” adoption: a study of their effects on the development of Korean orphans adopted into American families
Lien, N., Meyer, K., & Winick, M. (1977) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/30.10.1734 · Cited by 92 · see citing works
The effect of psychosocial stimulation on cognition and behaviour at 6 years in a cohort of term, low‐birthweight Jamaican children
Walker, S. P., Chang, S. M., Younger, N. O. M., & Grantham‐McGregor, S. (2010) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.2010.03637.x · Cited by 91 · see citing works
Effects of being born small for gestational age on long-term intellectual performance
Lundgren, E. M., & Tuvemo, T. (2008) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2008.01.014 · Cited by 91 · see citing works
Folate Status of Mothers During Pregnancy and Mental and Psychomotor Development of Their Children at Five Years of Age
Tamura, T., Goldenberg, R. L., Chapman, V. R., Johnston, K. E., Ramey, S. L., & Nelson, K. G. (2005) · PEDIATRICS · doi:10.1542/peds.2004-2189 · Cited by 89 · see citing works
Effects of Iron Supplementation of LBW Infants on Cognition and Behavior at 3 Years
Berglund, S. K., Westrup, B., Hägglöf, B., Hernell, O., & Domellöf, M. (2012) · PEDIATRICS · doi:10.1542/peds.2012-0989 · Cited by 88 · see citing works
Effects of iodine supplementation during pregnancy on child growth and development at school age
O’Donnell, K. J., Rakeman, M. A., Dou, Z.-H., Cao, X., Mei, Z. Y., DeLong, N., Brenner, G., Tai, M., Dong, W., & DeLong, G. R. (2002) · Developmental Medicine & Child Neurology · doi:10.1017/s0012162201001712 · Cited by 88 · see citing works
Impact of fatty acid status on growth and neurobehavioural development in humans
Makrides, M., Collins, C. T., & Gibson, R. A. (2011) · Maternal and Child Nutrition · doi:10.1111/j.1740-8709.2011.00304.x · Cited by 84 · see citing works
Iron Deficiency in Infancy and Mother-Child Interaction at 5 Years
Çorapçı, F., Radan, A., & Lozoff, B. (2006) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/00004703-200610000-00001 · Cited by 84 · see citing works
Socioeconomic Outcomes in Adults Malnourished in the First Year of Life: A 40-Year Study
Galler, J. R., Bryce, C. P., Waber, D. P., Zichlin, M. L., Fitzmaurice, G. M., & Eaglesfield, D. (2012) · PEDIATRICS · doi:10.1542/peds.2012-0073 · Cited by 80 · see citing works
The Assessment of Cognitive Performance in Children: Considerations for Detecting Nutritional Influences
Hughes, D., & Bryan, J. (2003) · Nutrition Reviews · doi:10.1301/nr.2003.dec.413-422 · Cited by 78 · see citing works
The Bacon Chow Study: Maternal Nutritional Supplementation and Infant Behavioral Development
Joos, S. K., Pollitt, E., Mueller, W. H., et al. (1983) · Child Development · doi:10.2307/1130054 · Cited by 78 · see citing works
The crucial role of thiamine in the development of syntax and lexical retrieval: a study of infantile thiamine deficiency
Fattal, I., Friedmann, N., & Fattal‐Valevski, A. (2011) · Brain · doi:10.1093/brain/awr068 · Cited by 77 · see citing works
Three-month nutritional supplementation in Indonesian infants and toddlers benefits memory function 8 y later
Pollitt, E., Watkins, W. E., & Husaini, M. (1997) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/66.6.1357 · Cited by 75 · see citing works
Maternal Multiple Micronutrient Supplements and Child Cognition: A Randomized Trial in Indonesia
Prado, E. L., Alcock, K., Muadz, H., Ullman, M. T., & Shankar, A. H. (2012) · PEDIATRICS · doi:10.1542/peds.2012-0412 · Cited by 75 · see citing works
Self-citation
Preschool Micronutrient Supplementation Effects on Intellectual and Motor Function in School-aged Nepalese Children
Khatry, S. K. (2012) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpediatrics.2012.37 · Cited by 74 · see citing works
Fetal and neonatal iron deficiency causes volume loss and alters the neurochemical profile of the adult rat hippocampus
Rao, R., Tkáč, I., Schmidt, A. T., & Georgieff, M. (2011) · Nutritional Neuroscience · doi:10.1179/1476830511y.0000000001 · Cited by 74 · see citing works
A Critical Link- Interventions for Physical Growth and Psychological Development
Pelto, G. H., Dickin, K., & Engle, P. L. (1999) · Nutritional Anthropology · doi:10.1525/nua.1999.22.2.21 · Cited by 73 · see citing works
Effects of Early Childhood Supplementation on the Educational Achievement of Women
Li, H., Barnhart, H. X., Stein, A. D., et al. (2003) · PEDIATRICS · doi:10.1542/peds.112.5.1156 · Cited by 73 · see citing works
Home Intervention Improves Cognitive and Social-Emotional Scores in Iron-Deficient Anemic Infants
Lozoff, B., Smith, J. B., Clark, K. M., Perales, C. G., Rivera, F., & Castillo, M. (2010) · PEDIATRICS · doi:10.1542/peds.2009-3535 · Cited by 72 · see citing works
Effect of Maternal Multivitamin Supplementation on the Mental and Psychomotor Development of Children Who Are Born to HIV-1–Infected Mothers in Tanzania
McGrath, N. M., Bellinger, D., Robins, J. M., et al. (2006) · PEDIATRICS · doi:10.1542/peds.2004-1668 · Cited by 71 · see citing works
RANDOMIZED TRIAL PROVIDES STRONG EVIDENCE THAT PROLONGED, EXCLUSIVE BREASTFEEDING ENHANCES COGNITIVE DEVELOPMENT IN CHILDREN; Kramer MS, Aboud F, Mironova E, Vanilovich I, Platt RW, Matush L, et al. Breastfeeding and child cognitive development: New evidence from a large randomized trial. Arch Gen Psychiatry 2008;65:578–84
Bond, S. M. (2008) · Journal of Midwifery & Women s Health · doi:10.1016/j.jmwh.2008.06.004 · Cited by 70 · see citing works
Effect of Pre- and Postnatal Essential Fatty Acid Deficiency on Brain Development and Myelination
McKenna, M. C., & Campagnoni, A. T. (1979) · Journal of Nutrition · doi:10.1093/jn/109.7.1195 · Cited by 69 · see citing works
Clinically Unapparent Infantile Thiamin Deficiency in Vientiane, Laos
Khounnorath, S., Chamberlain, K., Taylor, A. M., Soukaloun, D., Mayxay, M., Lee, S. J., Phengdy, B., Luangxay, K., Sisouk, K., Soumphonphakdy, B., et al. (2011) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0000969 · Cited by 65 · see citing works
Vitamin B6 and Cognitive Development: Recent Research Findings from Human and Animal Studies
Guilarte, T. R. (2009) · Nutrition Reviews · doi:10.1111/j.1753-4887.1993.tb03102.x · Cited by 65 · see citing works
Developmental Profiles of Polyunsaturated Fatty Acids in the Brain of Normal Infants and Patients with Peroxisomal Diseases: Severe Deficiency of Docosahexaenoic Acid in Zellweger�s and Pseudo-Zellweger�s Syndromes
Martinez, M. (2015) · World review of nutrition and dietetics · doi:10.1159/000419282 · Cited by 63 · see citing works
Early Brain Development and Plasticity
Couperus, J. W., & Nelson, C. A. (2008) · Blackwell Publishing Ltd eBooks · doi:10.1002/9780470757703.ch5 · Cited by 61 · see citing works
Effects of an energy and micronutrient supplement on mental development and behavior under natural conditions in undernourished children in Indonesia
Pollitt, E., Saco-Pollitt, C., Jahari, A. B., Husaini, M., & Huang, J.-F. (2000) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1601009 · Cited by 56 · see citing works
Dendritic development in neocortex of infants with early postnatal life undernutrition
Cordero, M. E., D'Acuña, E., Benveniste, S., et al. (1993) · Pediatric Neurology · doi:10.1016/0887-8994(93)90025-8 · Cited by 56 · see citing works
Cognitive and health measures following early nutritional supplementation: a sibling study.
Hicks, L. E., Langham, R. A., & Takenaka, J. (1982) · American Journal of Public Health · doi:10.2105/ajph.72.10.1110 · Cited by 56 · see citing works
Imprinting of hippocampal metabolism of choline by its availability during gestation: Implications for cholinergic neurotransmission
Blusztajn, J. K., Cermak, J. M., Holler, T., & Jackson, D. A. (1998) · Journal of Physiology-Paris · doi:10.1016/s0928-4257(98)80010-7 · Cited by 56 · see citing works
Breastfeeding and school achievement in Brazilian adolescents
Victora, C. G., Barros, F. C., Horta, B. L., et al. (2005) · Acta Paediatrica · doi:10.1080/08035250500252658 · Cited by 53 · see citing works
Development and behaviour of low‐birthweight term infants at 8 years in northeast Brazil: A longitudinal study
Emond, A. M., de Lira, P. I. C., Lima, M. D. C., Grantham‐McGregor, S., & Ashworth, A. (2006) · Acta Paediatrica · doi:10.1080/08035250600615127 · Cited by 50 · see citing works
Preschool Iron-Folic Acid and Zinc Supplementation in Children Exposed to Iron-Folic Acid in Utero Confers No Added Cognitive Benefit in Early School-Age
Christian, P. S., Morgan, M. E., Murray‐Kolb, L. E., LeClerq, S. C., Khatry, S. K., Schaefer, B. A., Cole, P. M., Katz, J., & Tielsch, J. M. (2011) · Journal of Nutrition · doi:10.3945/jn.111.146480 · Cited by 49 · see citing works
Diet during Lactation Associated with Infant Behavior and Caregiver-Infant Interaction in a Semirural Egyptian Village ,
Rahmanifar, A., Kirksey, A., Wachs, T. D., et al. (1993) · Journal of Nutrition · doi:10.1093/jn/123.2.164 · Cited by 48 · see citing works
Maternal gestational zinc supplementation does not influence multiple aspects of child development at 54 mo of age in Peru
Caulfield, L. E., Putnick, D. L., Zavaleta, N., Lazarte, F., Albornoz, C., Chen, P., DiPietro, J. A., & Bornstein, M. H. (2010) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2010.29407 · Cited by 48 · see citing works
Activity and Behavioral Development in Stunted and Nonstunted Children and Response to Nutritional Supplementation
Gardner, J. M., Grantham-McGregor, S. M., Chang, S. M., et al. (1995) · Child Development · doi:10.1111/j.1467-8624.1995.tb00965.x · Cited by 47 · see citing works
Developmental outcomes among 18‐month‐old Malawians after a year of complementary feeding with lipid‐based nutrient supplements or corn‐soy flour
Phuka, J. C., Gladstone, M., Maleta, K. M., Thakwalakwa, C. M., Cheung, Y. B., Briend, A., MANARY, M. J., & Ashorn, P. (2011) · Maternal and Child Nutrition · doi:10.1111/j.1740-8709.2011.00294.x · Cited by 46 · see citing works
Combined effects of noise and ototoxic drugs.
Falk, S. A. (1972) · Environmental Health Perspectives · doi:10.1289/ehp.72025 · Cited by 46 · see citing works
Nutritional effects on auditory brainstem maturation in healthy term infants
Ünay, B., Sarıcı, S. Ü., Ulaş, Ü. H., Akın, R., Alpay, F., & Gökçay, E. (2004) · Archives of Disease in Childhood - Fetal and Neonatal Edition · doi:10.1136/adc.2002.021014 · Cited by 44 · see citing works
The influence of protein restriction, rehabilitation and changing nutritional status on synaptic development: A quantitative study in rat brain
Jones, D. G., & Dyson, S. E. (1981) · Brain Research · doi:10.1016/0006-8993(81)90623-5 · Cited by 43 · see citing works
Activity and Behavioral Development in Stunted and Nonstunted Children and Response to Nutritional Supplementation
Gardner, J. M., Grantham‐McGregor, S., Chang, S. M., et al. (1995) · Child Development · doi:10.2307/1131910 · Cited by 43 · see citing works
Low Birth Weight, Prematurity, and Paternal Social Status: Impact on the Basic Competence Test in Taiwanese Adolescents
Wang, W.-L., Sung, Y., Sung, F.-C., Lu, T., Kuo, S., & Li, C. (2008) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2008.04.017 · Cited by 41 · see citing works
No effect of maternal micronutrient supplementation on early childhood growth in rural western China: 30 month follow-up evaluation of a double blind, cluster randomized controlled trial
Wang, W., Yan, H., Zeng, L., Cheng, Y., Wang, D., & Li, Q. (2011) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2011.190 · Cited by 40 · see citing works
[Effects of nutrient fortified complementary food supplements on development of infants and young children in poor rural area of Gansu Province].
Yy, W., Wang, F.-Z., Wang, K. A., et al. (2006) · PubMed · Cited by 39 · see citing works
The development of 3- to 9-month-old infants in two cultural contexts: Bayley longitudinal results for Cameroonian and German infants
Vierhaus, M., Lohaus, A., Kolling, T., et al. (2010) · European Journal of Developmental Psychology · doi:10.1080/17405629.2010.505392 · Cited by 36 · see citing works
Low birthweight and subsequent emotional and behavioural outcomes in 12-year-old children in Soweto, South Africa: findings from Birth to Twenty
Sabet, F., Richter, L., Ramchandani, P. G., Stein, A. L., QUIGLEY, M. A., & Norris, S. A. (2009) · International Journal of Epidemiology · doi:10.1093/ije/dyp204 · Cited by 36 · see citing works
Food insecurity and perceived stress but not HIV infection are independently associated with lower energy intakes among lactating Ghanaian women
Addo, A. A., Marquis, G. S., Lartey, A. A., Pérez‐Escamilla, R., Mazur, R., & Harding, K. (2010) · Maternal and Child Nutrition · doi:10.1111/j.1740-8709.2009.00229.x · Cited by 33 · see citing works
Effects of Perinatal Vitamin B6 Deficiency on Dopaminergic Neurochemistry
Guilarte, T. R., Wagner, H. N., & Frost, J. J. (1987) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1987.tb04111.x · Cited by 33 · see citing works
Effects of Vitamin B-6 Deficiency on the Developing Central Nervous System of the Rat. Myelination
Morré, D. M., Kirksey, A., & Das, G. D. (1978) · Journal of Nutrition · doi:10.1093/jn/108.8.1260 · Cited by 33 · see citing works
The effect of nutritional supplementation on physical activity and exploratory behavior of Mexican infants aged 8–12 months
Aburto, N., Ramírez‐Zea, M., Neufeld, L. M., et al. (2010) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2010.52 · Cited by 32 · see citing works
Effects of Vitamin B-6 Deficiency on Morphological Changes in Dendritic Trees of Purkinje Cells in Developing Cerebellum of Rats
Chang, S.-J., Kirksey, A., & Morré, D. M. (1981) · Journal of Nutrition · doi:10.1093/jn/111.5.848 · Cited by 31 · see citing works
Daily Supplementation with Iron Plus Folic Acid, Zinc, and Their Combination Is Not Associated with Younger Age at First Walking Unassisted in Malnourished Preschool Children from a Deficient Population in Rural Nepal
Katz, J., Khatry, S. K., LeClerq, S. C., Mullany, L. C., Yanik, E. L., Stoltzfus, R. J., Siegel, E. H., & Tielsch, J. M. (2010) · Journal of Nutrition · doi:10.3945/jn.109.119925 · Cited by 29 · see citing works
Dendritic morphology and orientation of pyramidal cells of the neocortex in two groups of early postnatal undernourished–rehabilitated rats
Cordero, M. E., Valenzuela, C. Y., Rodríguez, Á., & Aboitiz, F. (2003) · Developmental Brain Research · doi:10.1016/s0165-3806(03)00013-0 · Cited by 27 · see citing works
Effects of Maternal Restriction in Vitamin B-6 on Neocortex Development in Rats: Neuron Differentiation and Synaptogenesis
Groziak, S. M., & Kirksey, A. (1990) · Journal of Nutrition · doi:10.1093/jn/120.5.485 · Cited by 25 · see citing works
Model-based analysis and quantification of age trends in auditory evoked potentials
Kerr, C. C., RENNIE, C. J., & Robinson, P. A. (2010) · Clinical Neurophysiology · doi:10.1016/j.clinph.2010.05.030 · Cited by 24 · see citing works
The Behavioral Consequences of Protein-Energy Deprivation and Supplementation in Early Life: An Epidemiological Perspective
Rush, D. (1984) · Springer eBooks · doi:10.1007/978-1-4615-7219-0_5 · Cited by 14 · see citing works
Effects of an energy and micronutrient supplement on growth and activity, correcting for non-supplemental sources of energy input in undernourished children in Indonesia
Aitchison, T. C., Durnin, J., Beckett, C., et al. (2000) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1601007 · Cited by 14 · see citing works
Morphologic study on cerebral cortex development in therapeutically aborted fetuses in an endemic goiter region in Guizhou.
Jl, L., Zj, Z., Tan, Y. B., et al. (1984) · PubMed · Cited by 12 · see citing works

Flagged first, then by citations

Research works printed but not linked: 3

Beard JL, Connor JR. Iron status and neural functioning. Annu Rev Nutr. 2003;23:41-58.
Chen ZP, Chen XX, Dong L, et al. The iodine deficient rat. In: Medeiros-Neto G, Maciel RMB, Halpern A, eds. Iodine Deficiency Diseases and Congenital Hypothyroidism. Sao Paolo: Ache Press; 1986:46-51.
Kolb B, Gibb R. Early brain injury, plasticity, and behavior. In: Nelson CA, Luciana M, eds. Handbook of Developmental Neuroscience. Cambridge, MA: MIT Press; 2001:175-190.

Sorted by citations

Nutritional psychiatry: Towards improving mental health by what you eat
Adan, R. A. H., van der Beek, E. M., Buitelaar, J. K., Cryan, J. F., Hebebrand, J., Higgs, S., Schellekens, H., & Dickson, S. L. (2019) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2019.10.011 · Cited by 454 · see citing works
Prenatal developmental origins of future psychopathology: mechanisms and pathways
Monk, C., Lugo-Candelas, C., & Trumpff, C. (2019) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-050718-095539 · Cited by 388 · see citing works
Global health and development in early childhood
Aboud, F. E., & Yousafzai, A. K. (2015) · Annual Review of Psychology · doi:10.1146/annurev-psych-010814-015128 · Cited by 398 · see citing works
Nutritional patterns associated with the maintenance of neurocognitive functions and the risk of dementia and Alzheimer's disease: a focus on human studies
Pistollato, F., Iglesias, R. C., Ruiz, R., Aparicio, S., Crespo, J., Lopez, L. D., Manna, P. P., Giampieri, F., & Battino, M. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2018.03.012 · Cited by 247 · see citing works
Role of diet and its effects on the gut microbiome in the pathophysiology of mental disorders
Horn, J., Mayer, D. E., Chen, S., & Mayer, E. A. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-01922-0 · Cited by 193 · see citing works
The importance of maternal diet quality during pregnancy on cognitive and behavioural outcomes in children: a systematic review and meta-analysis
Borge, T. C., Aase, H., Brantsæter, A. L., & Biele, G. (2017) · BMJ Open · doi:10.1136/bmjopen-2017-016777 · Cited by 186 · see citing works
Administration of Non-Absorbable Antibiotics to Pregnant Mice to Perturb the Maternal Gut Microbiota Is Associated with Alterations in Offspring Behavior
Tochitani, S., Ikeno, T., Ito, T., Sakurai, A., Yamauchi, T., & Matsuzaki, H. (2016) · PLOS ONE · doi:10.1371/journal.pone.0138293 · Cited by 157 · see citing works
Report of the intergovernmental panel on climate change: implications for the mental health policy of children and adolescents in Europe—a scoping review
Clemens, V., von Hirschhausen, E., & Fegert, J. M. (2022) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-020-01615-3 · Cited by 147 · see citing works
Nutrition in Children and Adolescents
Corkins, M. R., Daniels, S. R., de Ferranti, S. D., Golden, N. H., Kim, J. H., Magge, S. N., & Schwarzenberg, S. J. (2016) · Medical Clinics of North America · doi:10.1016/j.mcna.2016.06.005 · Cited by 137 · see citing works
Biosynthesis of Triacylglycerol Molecules with a Tailored PUFA Profile in Industrial Microalgae
Xin, Y., Shen, C., She, Y., Chen, H., Wang, C., Wei, L., Yoon, K., Han, D., Hu, Q., & Xu, J. (2019) · Molecular Plant · doi:10.1016/j.molp.2018.12.007 · Cited by 108 · see citing works
Preventing adolescent stress-induced cognitive and microbiome changes by diet
Provensi, G., Schmidt, S. D., Boehme, M., Bastiaanssen, T. F. S., Rani, B., Costa, A., Busca, K., Fouhy, F., Strain, C., Stanton, C., et al. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1820832116 · Cited by 110 · see citing works
Managing diabetes in preschool children
Sundberg, F., Barnard, K., Cato, A., de Beaufort, C., DiMeglio, L. A., Dooley, G., Hershey, T., Hitchcock, J., Jain, V., Weissberg-Benchell, J., et al. (2017) · Pediatric Diabetes · doi:10.1111/pedi.12554 · Cited by 91 · see citing works
Vitamin B-12 status in infancy is positively associated with development and cognitive functioning 5 y later in Nepalese children
Kvestad, I., Hysing, M., Shrestha, M., Ulak, M., Thorne-Lyman, A. L., Henjum, S., Ueland, P. M., Midttun, Ø., Fawzi, W., Chandyo, R. K., et al. (2017) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.116.144931 · Cited by 92 · see citing works
Education outcomes in the era of global climate change
Prentice, C. M., Vergunst, F., Minor, K., & Berry, H. L. (2024) · Nature Climate Change · doi:10.1038/s41558-024-01945-z · Cited by 70 · see citing works
Very Early Childhood Development
Aboud, F. E., & Yousafzai, A. K. (2016) · Disease Control Priorities, Third Edition (Volume 2): Reproductive, Maternal, Newborn, and Child Health · doi:10.1596/978-1-4648-0348-2_ch13 · Cited by 27 · see citing works

Anaemia in the Hospitalized Elderly in Tanzania: Prevalence, Severity, and Micronutrient Deficiency Status
Chamba, C. C., Nasser, A., Mawalla, W. F., et al. (2021) · Anemia · doi:10.1155/2021/9523836 · Cited by 9 · see citing works
Risk factors of anaemia and iron deficiency in Somali children and women: Findings from the 2019 Somalia Micronutrient Survey
Wirth, J. P., Sesay, F., Mbai, J., Ali, S. I., Donkor, W. E. S., Woodruff, B. A., Pilane, Z., Mohamud, K. M., Muse, A., Yussuf, H. O., et al. (2022) · Maternal & Child Nutrition · doi:10.1111/mcn.13254 · Cited by 17 · see citing works
Anaemia and micronutrient deficiencies
van den Broek, N. R. (2003) · British Medical Bulletin · doi:10.1093/bmb/ldg004 · Cited by 110 · see citing works
The prevalence of Iron Deficiency and Its Anemia in 1-5 Years Old Children and Their Mothers in Birjand City
Fesharakinia, A. (2014) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 1 · see citing works
Iron deficiency and cognitive functions
Jáuregui-Lobera, I. (2014) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s72491 · Cited by 320 · see citing works

Authors: Prado, E. L., & Dewey, K. G.
Affiliations: University of California, Davis (US)
ORCID: Prado, Elizabeth L
Dewey, Kathryn G
Venue: Nutrition Reviews
Publisher: Oxford University Press (OUP)
Published: 2014-03-28
Volume: 72
Issue: 4
Pages: 267-284
ISSN: 0029-6643 (ISSN-L)
DOI: 10.1111/nure.12102
OpenAlex: W2155746491
Cited by: 1,036
References: 203
Citations by year: 2026: 101 · 2025: 109 · 2024: 106 · 2023: 92 · 2022: 107 · 2021: 110 · 2020: 96 · 2019: 88 · 2018: 58 · 2017: 66 · 2016: 51 · 2015: 36 · 2014: 7 · 2013: 5 · 2012: 2
FWCI: 6.11
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Nutrition Reviews (publishedVersion)
PubMed (publishedVersion)
Funders: Bill and Melinda Gates Foundation
University of California, Davis
Topics: Health Sciences › Nursing › Nutrition and Dietetics › Child Nutrition and Water Access
Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Public Health and Nutrition
Keywords: brain development, early life nutrition, nutritional deficiency, cognitive function, severe acute malnutrition, chronic malnutrition, iron deficiency, iodine deficiency, salt iodization, micronutrient powders, iron supplementation, essential fatty acids, pregnancy, infancy, low- and middle-income countries
MeSH terms: Iron Deficiencies, Animals, Brain, Child, Preschool, Cognition, Female, Food, Fortified, Humans, Infant, Infant, Newborn, Iodine, Iron, Male, Minerals, Nutritional Requirements, Nutritional Status, Pregnancy, Trace Elements, Sodium Chloride, Dietary, Micronutrients, Dietary Supplements, Models, Animal

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Nutrition and brain development in early life

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Self-check

Cites

Cited by

Related

Record

About these checks