The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Interaction of Steroid Hormone Receptors with the Transcription Initiation Complex
Abstract
REGULATION of gene expression by steroid hormones is a traditional field of molecular endocrinology. The hormones act by binding to intracellular receptors, which themselves orchestrate the transcriptional response. After the cloning of the hormone receptors and the identification of their target sequences on DNA at the end of the 1980s, the question of how steroid hormones modulate the activity of various genes in target cells seemed to be solved. It was clear that steroid hormone receptors are ligand-activated transcriptional modulators, which in most cases act through binding to specific sequences on DNA called hormone-responsive elements (HREs) (1). Careful mutational analysis identified a modular structure of the receptors composed of a DNA-binding domain, nuclear localization signals, a ligand-binding domain, and several transactivation domains (2). Interactions of the receptors with components of the basal transcriptional machinery and with sequence-specific transcription factors were assumed to mediate their transcriptional effects. The prevalent opinion was that the mechanism of action of steroid hormones was a closed chapter ready for the textbooks and what remained to be done to complete the picture was merely the collection of details.
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Cites
Gene regulation by steroid hormones
Beato, M. (1989) · Cell · doi:10.1016/0092-8674(89)90237-7 · Cited by 3,383
Self-citationPhosphorylated CREB binds specifically to the nuclear protein CBP
Chrivia, J. C., Kwok, R. P. S., Lamb, N., Hagiwara, M., Montminy, M. R., & Goodman, R. H. (1993) · Nature · doi:10.1038/365855a0 · Cited by 2,052
Nuclear protein CBP is a coactivator for the transcription factor CREB
Kwok, R. P. S., Lundblad, J. R., Chrivia, J. C., Richards, J. P., Bächinger, H. P., Brennan, R. G., Roberts, S. G. E., Green, M. R., & Goodman, R. H. (1994) · Nature · doi:10.1038/370223a0 · Cited by 1,443
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A family of transcriptional adaptor proteins targeted by the E1A oncoprotein
Arany, Z., Newsome, D., Oldread, E., Livingston, D. M., & Eckner, R. (1995) · Nature · doi:10.1038/374081a0 · Cited by 533
Distinct functions for the two importin subunits in nuclear protein import
Görlich, D., Vogel, F., Mills, A. D., Hartmann, E., & Laskey, R. A. (1995) · Nature · doi:10.1038/377246a0 · Cited by 474
E1A-associated p300 and CREB-associated CBP belong to a conserved family of coactivators
Arany, Z. (1994) · Cell · doi:10.1016/0092-8674(94)90127-9 · Cited by 444
Cited by
Sapolsky, R. M., Romero, L. M., & Munck, A. U. (2000) · Endocrine Reviews · doi:10.1210/edrv.21.1.0389 · Cited by 7,541
Molecular basis of agonism and antagonism in the oestrogen receptor
Brzozowski, A. M., Pike, A. C. W., Dauter, Z., Hubbard, R. E., Bonn, T., Engström, O., Öhman, L., Greene, G. L., Gustafsson, J.-Å., & Carlquist, M. (1997) · Nature · doi:10.1038/39645 · Cited by 3,355
Brain corticosteroid receptor balance in health and disease
de Kloet, E. R., Vreugdenhil, E., Oitzl, M. S., & Joëls, M. (1998) · Endocrine Reviews · doi:10.1210/edrv.19.3.0331 · Cited by 2,614
Stress and cognition: are corticosteroids good or bad guys?
de Kloet, E. R., Oitzl, M. S., & Joëls, M. (1999) · Trends in Neurosciences · doi:10.1016/s0166-2236(99)01438-1 · Cited by 1,258
Sex hormones and the immune response in humans
Bouman, A., Heineman, M. J., & Faas, M. M. (2005) · Human Reproduction Update · doi:10.1093/humupd/dmi008 · Cited by 1,131
Metadata
- Authors
- BEATO, M., & SÁNCHEZ-PACHECO, A.
- Venue
- Endocrine Reviews
- Publisher
- The Endocrine Society
- Published
- 1996-12
- Volume
- 17
- Issue
- 6
- Pages
- 587-609
- ISSN
- 0163-769X (ISSN-L)
- 1945-7189
- OpenAlex
- W2091322528
- Cited by
- 405
- References
- 7
- FWCI
- 15.44
- Type
- journal article
- Language
- en
- Open access
- closed
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- BEATO, M., & SÁNCHEZ-PACHECO, A. (1996). Interaction of Steroid Hormone Receptors with the Transcription Initiation Complex. Endocrine Reviews. https://doi.org/10.1210/edrv-17-6-587
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
