Fibroblast Growth Factor 21 Regulates Lipolysis in White Adipose Tissue But Is Not Required for Ketogenesis and Triglyceride Clearance in Liver

FGF-21 as a novel metabolic regulator

Kharitonenkov, A., Shiyanova, T. L., Koester, A., Ford, A. M., Micanovic, R., Galbreath, E. J., Sandusky, G. E., Hammond, L. J., Moyers, J. S., Owens, R. A., et al. (2005) · Journal of Clinical Investigation · doi:10.1172/jci23606 · Cited by 2,125

Peroxisome proliferator–activated receptor α mediates the adaptive response to fasting

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Endocrine Regulation of the Fasting Response by PPARα-Mediated Induction of Fibroblast Growth Factor 21

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Hepatic Fibroblast Growth Factor 21 Is Regulated by PPARα and Is a Key Mediator of Hepatic Lipid Metabolism in Ketotic States

Badman, M. K., Pissios, P., Kennedy, A. R., Koukos, G., Flier, J. S., & Maratos-Flier, E. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.05.002 · Cited by 1,495

Fuel Metabolism in Starvation

Cahill, G. F. (2006) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.26.061505.111258 · Cited by 1,360

Evolution of the Fgf and Fgfr gene families.

Itoh, N., & Ornitz, D. (2004) · Trends in Genetics · doi:10.1016/j.tig.2004.08.007 · Cited by 1,123

Fibroblast Growth Factor 21 Corrects Obesity in Mice

Coskun, T., Bina, H. A., Schneider, M. A., Dunbar, J. D., Hu, C. C., Chen, Y., Moller, D. E., & Kharitonenkov, A. (2008) · Endocrinology · doi:10.1210/en.2008-0816 · Cited by 1,031

A critical role for the peroxisome proliferator-activated receptor α (PPARα) in the cellular fasting response: The PPARα-null mouse as a model of fatty acid oxidation disorders

Leone, T. C., Weinheimer, C. J., & Kelly, D. P. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.13.7473 · Cited by 943

Identification of a novel FGF, FGF-21, preferentially expressed in the liver

Nishimura, T., Nakatake, Y., Konishi, M., & Itoh, N. (2000) · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · doi:10.1016/s0167-4781(00)00067-1 · Cited by 847

Functions and regulations of fibroblast growth factor signaling during embryonic development

Thisse, B., & Thisse, C. (2005) · Developmental Biology · doi:10.1016/j.ydbio.2005.09.011 · Cited by 508

Glucagon resistance and metabolic-associated steatotic liver disease: a review of the evidence

McGlone, E. R., Bloom, S. R., & Tan, T. (2024) · Journal of Endocrinology · doi:10.1530/joe-23-0365 · Cited by 30

Improved FGF21 Sensitivity and Restored FGF21 Signaling Pathway in High-Fat Diet/Streptozotocin-Induced Diabetic Rats After Duodenal-Jejunal Bypass and Sleeve Gastrectomy

Liu, Q., Wang, S., Wei, M., Huang, X., Cheng, Y., Shao, Y., Xia, P., Zhong, M., Liu, S., Zhang, G., et al. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00566 · Cited by 27

Association between insulin resistance and impairment of FGF21 signal transduction in skeletal muscles

Jeon, J. Y., Choi, S., Ha, E. S., Kim, T. H., Jung, J. G., Han, S. J., Kim, H. J., Kim, D. J., KANG, Y. Y., & Lee, K. W. (2016) · Endocrine · doi:10.1007/s12020-015-0845-x · Cited by 26

β-Klotho deficiency shifts the gut-liver bile acid axis and induces hepatic alterations in mice

Somm, E., Henry, H., Bruce, S. J., Bonnet, N., Montandon, S. A., Niederländer, N. J., Messina, A., Aeby, S., Rosikiewicz, M., Fajas, L., et al. (2018) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00182.2018 · Cited by 28

Involvement of heparan sulfate 6-O-sulfation in the regulation of energy metabolism and the alteration of thyroid hormone levels in male mice

Nagai, N., Habuchi, H., Sugaya, N., Nakamura, M., Imamura, T., Watanabe, H., & Kimata, K. (2013) · Glycobiology · doi:10.1093/glycob/cwt037 · Cited by 25

Chronic Prednisolone Treatment Reduces Hepatic Insulin Sensitivity while Perturbing the Fed-to-Fasting Transition in Mice

Laskewitz, A. J., van Dijk, T. H., Bloks, V. W., Reijngoud, D., van Lierop, M.-J., Dokter, W. H. A., Kuipers, F., Groen, A. K., & Grefhorst, A. (2010) · Endocrinology · doi:10.1210/en.2009-1374 · Cited by 26

Protein status modulates the rewarding value of foods and meals to maintain an adequate protein intake

Tomé, D., Chaumontet, C., Even, P. C., Darcel, N., & Azzout-Marniche, D. (2019) · Physiology & Behavior · doi:10.1016/j.physbeh.2019.03.012 · Cited by 24

Enterohepatic Transcription Factor CREB3L3 Protects Atherosclerosis via SREBP Competitive Inhibition

Nakagawa, Y., Wang, Y., Han, S., Okuda, K., Oishi, A., Yagishita, Y., Kumagai, K., Ohno, H., Osaki, Y., Mizunoe, Y., et al. (2020) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2020.11.004 · Cited by 24

FoxO1 suppresses Fgf21 during hepatic insulin resistance to impair peripheral glucose utilization and acute cold tolerance

Stöhr, O., Tao, R., Miao, J., Copps, K. D., & White, M. F. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.108893 · Cited by 24

Hepatic p38 Activation Modulates Systemic Metabolism Through FGF21-Mediated Interorgan Communication

Liu, W., Sun, C., Yan, Y., Cao, H., Niu, Z., Shen, S., Liu, S., Wu, Y., Yan, L., Hui, L., et al. (2021) · Diabetes · doi:10.2337/db21-0240 · Cited by 24

Nutritional regulation of fibroblast growth factor 21: from macronutrients to bioactive dietary compounds

Pérez‐Martí, A., Sandoval, V., Marrero, P. F., Haro, D., & Relat, J. (2016) · Hormone Molecular Biology and Clinical Investigation · doi:10.1515/hmbci-2016-0034 · Cited by 24

Fasting decreases plasma FGF21 in obese subjects and the expression of FGF21 receptors in adipose tissue in both lean and obese subjects

Nygaard, E. B., Ørskov, C., Almdal, T., Vestergaard, H., & Andersen, B. (2018) · Journal of Endocrinology · doi:10.1530/joe-18-0002 · Cited by 24

Endoplasmic reticulum stress induces up-regulation of hepatic β-Klotho expression through ATF4 signaling pathway

Dong, K., Li, H., Zhang, M., Jiang, S., Chen, S., Zhou, J., Dai, Z., Fang, Q., & Jia, W. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.02.104 · Cited by 23

Alterations in Hepatic FGF21, Co-Regulated Genes, and Upstream Metabolic Genes in Response to Nutrition, Ketosis and Inflammation in Peripartal Holstein Cows

Akbar, H., Batistel, F., Drackley, J. K., & Loor, J. J. (2015) · PLoS ONE · doi:10.1371/journal.pone.0139963 · Cited by 23

Adipose tissue autophagy and homeostasis in alcohol-induced liver injury

Li, Y., & Ding, W. (2017) · Liver Research · doi:10.1016/j.livres.2017.03.004 · Cited by 23

Fibroblast growth factor signaling in non-alcoholic fatty liver disease and non-alcoholic steatohepatitis: Paving the way to hepatocellular carcinoma

Ocker, M. (2020) · World Journal of Gastroenterology · doi:10.3748/wjg.v26.i3.279 · Cited by 23

Fibroblast growth factor 21: A “rheostat” for metabolic regulation?

She, Q.-Y., Bao, J., Wang, H.-Z., Liang, H., Huang, W., Wu, J., Zhong, Y.-W., Ling, H., Li, A., & Qin, S.-L. (2022) · Metabolism · doi:10.1016/j.metabol.2022.155166 · Cited by 22

Hepatocyte-Secreted Autotaxin Exacerbates Nonalcoholic Fatty Liver Disease Through Autocrine Inhibition of the PPARα/FGF21 Axis

Qiu, H., Song, E., Hu, Y., Li, T., Ku, K. C., Wang, C., Cheung, B. M. Y., Cheong, L. Y., Wang, Q., Wu, X., et al. (2022) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2022.07.012 · Cited by 22

FGF21 Alleviates Hepatic Endoplasmic Reticulum Stress under Physiological Conditions

Maruyama, R., Shimizu, M., Hashidume, T., Inoue, J., Itoh, N., & Sato, R. (2018) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.64.200 · Cited by 21

Leptin, Acting at Central Level, Increases FGF21 Expression in White Adipose Tissue via PPARβ/δ

Mazuecos, L., Pintado, C., Rubio, B., Guisantes-Batán, E., Andrés, A., & Gallardo, N. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22094624 · Cited by 21

BACH1 inhibits senescence, obesity, and short lifespan by ferroptotic FGF21 secretion

Nishizawa, H., Matsumoto, M., Yamanaka, M., Irikura, R., Nakajima, K., Tada, K., Nakayama, Y., Konishi, M., Itoh, N., Funayama, R., et al. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114403 · Cited by 21

Fibroblast growth factor 21 deletion aggravates diabetes-induced pathogenic changes in the aorta in type 1 diabetic mice

Yan, X., Chen, J., Zhang, C., Zeng, J., Zhou, S., Zhang, Z., Lu, X., Chen, J., Feng, W., Li, X., et al. (2015) · Cardiovascular Diabetology · doi:10.1186/s12933-015-0241-0 · Cited by 21

Fibroblast Growth Factor 21 Levels in Young Healthy Females Display Day and Night Variations and Are Increased in Response to Short-Term Energy Deprivation Through a Leptin-Independent Pathway

Foo, J., Aronis, K. N., Chamberland, J. P., Paruthi, J., Moon, H., & Mantzoros, C. S. (2012) · Diabetes Care · doi:10.2337/dc12-0497 · Cited by 21

Fibroblast growth factor-21 (FGF21) administration to early-lactating dairy cows. II. Pharmacokinetics, whole-animal performance, and lipid metabolism

Caixeta, L. S., Giesy, S. L., Krumm, C. S., Perfield, J. W., Butterfield, A. M., & Boisclair, Y. R. (2019) · Journal of Dairy Science · doi:10.3168/jds.2019-16696 · Cited by 20

Dietary medium-chain fatty acids reduce hepatic fat accumulation via activation of a CREBH-FGF21 axis

Cao, Y., Araki, M., Nakagawa, Y., Deisen, L., Lundsgaard, A., Kanta, J. M., Holm, S. K., Johann, K., Jacobsen, J. C., Jähnert, M., et al. (2024) · Molecular Metabolism · doi:10.1016/j.molmet.2024.101991 · Cited by 25

Ameliorative role of bioactive phytoconstituents targeting obesity associated NAFLD by modulation of inflammation and lipogenesis pathways: a comprehensive review

Barbhuiya, P. A., Sen, S., & Pathak, M. P. (2023) · Phytochemistry Reviews · doi:10.1007/s11101-023-09912-w · Cited by 20

Function and Regulation of Bone Marrow Adipose Tissue in Health and Disease: State of the Field and Clinical Considerations

Zhang, X., Tian, L., Majumdar, A., & Scheller, E. L. (2024) · Comprehensive Physiology · doi:10.1002/j.2040-4603.2024.tb00300.x · Cited by 18

Fibroblast growth factor 21: update on genetics and molecular biology

Barros, D. R., & Hegele, R. A. (2024) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000960 · Cited by 18

Crosstalk of hepatocyte nuclear factor 4a and glucocorticoid receptor in the regulation of lipid metabolism in mice fed a high-fat-high-sugar diet

Lü, H., Lei, X., Guo, S., Winkler, R., John, S., Kumar, D., Li, W., & Alnouti, Y. (2022) · Lipids in Health and Disease · doi:10.1186/s12944-022-01654-6 · Cited by 20

Adipose Tissue Dysfunction and Energy Balance Paradigms in People Living With HIV

Ramirez, C. E., Agarwal, N., Cox, A. R., Hartig, S. M., Lake, J. E., & Balasubramanyam, A. (2023) · Endocrine Reviews · doi:10.1210/endrev/bnad028 · Cited by 21

Causative and Sanative dynamicity of ChREBP in Hepato-Metabolic disorders

Daniel, P. V., & Mondal, P. (2020) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2020.151128 · Cited by 18

Cancer-associated adipocytes mediate CD8+T cell dysfunction via FGF21-driven lipolysis

Dalangood, S., Hu, C., Yuan, C., Li, X. O., Qiao, W., Li, H., Zhang, R., Li, L., Peng, L., Yu, X., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.116526 · Cited by 18

Fibroblast Growth Factor 21 Is Not Required for the Reductions in Circulating Insulin-Like Growth Factor-1 or Global Cell Proliferation Rates in Response to Moderate Calorie Restriction in Adult Mice

Thompson, A. C. S., Bruss, M. D., Nag, N., Kharitonenkov, A., Adams, A. C., & Hellerstein, M. K. (2014) · PLoS ONE · doi:10.1371/journal.pone.0111418 · Cited by 17

Fibroblast Growth Factor 21-Null Mice Do Not Exhibit an Impaired Response to Fasting

Antonellis, P. J., Hayes, M. P., & Adams, A. C. (2016) · Frontiers in Endocrinology · doi:10.3389/fendo.2016.00077 · Cited by 17

Protein Status Modulates an Appetite for Protein To Maintain a Balanced Nutritional State—A Perspective View

Tomé, D., Chaumontet, C., Even, P. C., Darcel, N., Thornton, S. N., & Azzout‐Marniche, D. (2019) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.9b05990 · Cited by 19

Physiology and Endocrinology Symposium: FGF21: Insights into mechanism of action from preclinical studies1,2

Antonellis, P. J., Kharitonenkov, A., & Adams, A. C. (2014) · Journal of Animal Science · doi:10.2527/jas.2013-7076 · Cited by 15

Long-term adjustment of hepatic lipid metabolism after chronic stress and the role of FGF21

Dille, M. A., Nikolic, A., Wahlers, N., Fahlbusch, P., Jacob, S., Hartwig, S., Lehr, S., Kabra, D. G., Klymenko, O., Al‐Hasani, H., et al. (2021) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2021.166286 · Cited by 16

A human laboratory study on the link between alcohol administration and circulating fibroblast growth factor 21 (FGF21) in individuals with alcohol use disorder

Farokhnia, M., Wang, T., Jourdan, T., Godlewski, G., Farinelli, L. A., Kunos, G., & Leggio, L. (2023) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2023.109809 · Cited by 16

Enhanced Hepatic PPARα Activity Links GLUT8 Deficiency to Augmented Peripheral Fasting Responses in Male Mice

Mayer, A. L., Zhang, Y., Feng, E. H., Higgins, C. B., Adenekan, O., Pietka, T., Beatty, W. L., & DeBosch, B. J. (2018) · Endocrinology · doi:10.1210/en.2017-03150 · Cited by 16

Leukotriene-B4 modulates macrophage metabolism and fat loss in type 1 diabetic mice

Ramalho, T. R. D. O., Ramalingam, L., Filgueiras, L. R., Festuccia, W. T., Jancar, S., & Moustaïd‐Moussa, N. (2019) · Journal of Leukocyte Biology · doi:10.1002/jlb.ma1218-477rr · Cited by 16

Spontaneous Browning of White Adipose Tissue Improves Angiogenesis and Reduces Macrophage Infiltration After Fat Grafting in Mice

Lin, J., Zhu, S., Liao, Y., Liang, Z., Quan, Y., He, Y., Cai, J., & Lu, F. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.845158 · Cited by 16

Fibroblast growth factor 21 improves glucose homeostasis partially via down-regulation of Na+-d-glucose cotransporter SGLT1 in the small intestine

Wang, N., Li, S., Guo, X., Li, J., Ren, G., & Li, D. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.10.198 · Cited by 15

CREBH Improves Diet-Induced Obesity, Insulin Resistance, and Metabolic Disturbances by FGF21-Dependent and FGF21-Independent Mechanisms

Satoh, A., Han, S., Araki, M., Nakagawa, Y., Ohno, H., Mizunoe, Y., Kumagai, K., Murayama, Y., Osaki, Y., IWASAKI, H. O., et al. (2020) · iScience · doi:10.1016/j.isci.2020.100930 · Cited by 15

Fgf21 regulates T-cell development in the neonatal and juvenile thymus

Nakayama, Y., Masuda, Y., Ohta, H., Tanaka, T., Washida, M., Nabeshima, Y., Miyake, A., Itoh, N., & Konishi, M. (2017) · Scientific Reports · doi:10.1038/s41598-017-00349-8 · Cited by 15

Exploring endocrine FGFs - structures, functions and biomedical applications

Phan, P. (2024) · International Journal of Biochemistry and Molecular Biology · doi:10.62347/palk2137 · Cited by 16

Hepatokines, bile acids and ketone bodies are novel Hormones regulating energy homeostasis

Garruti, G., Baj, J., Cignarelli, A., Perrini, S., & Giorgino, F. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1154561 · Cited by 15

Very low-density lipoprotein receptor increases in a liver-specific manner due to protein deficiency but does not affect fatty liver in mice

Oshio, Y., Hattori, Y., Kamata, H., Ozaki‐Masuzawa, Y., Seki, A., Tsuruta, Y., & Takenaka, A. (2021) · Scientific Reports · doi:10.1038/s41598-021-87568-2 · Cited by 14

Ketone body and FGF21 coordinately regulate fasting-induced oxidative stress response in the heart

Kawakami, R., Sunaga, H., Iso, T., Kaneko, R., Koitabashi, N., Obokata, M., Harada, T., Matsui, H., Yokoyama, T., & Kurabayashi, M. (2022) · Scientific Reports · doi:10.1038/s41598-022-10993-4 · Cited by 14

The Role of Kupffer Cells as Mediators of Adipose Tissue Lipolysis

Ma, W., Zhao, D., He, F., & Tang, L. (2019) · The Journal of Immunology · doi:10.4049/jimmunol.1900366 · Cited by 14

What does self‐selection of dietary proteins in rats tell us about protein requirements and body weight control?

Even, P. C., Gehring, J., & Tomé, D. (2021) · Obesity Reviews · doi:10.1111/obr.13194 · Cited by 17

Cell autonomous requirement of neurofibromin (Nf1) for postnatal muscle hypertrophic growth and metabolic homeostasis

Wei, X., Franke, J., Ost, M., Wardelmann, K., Börno, S. T., Timmermann, B., Meierhofer, D., Kleinridders, A., Klaus, S., & Stricker, S. (2020) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.12632 · Cited by 12

Endocrine and autocrine/paracrine modulators of brown adipose tissue mass and activity as novel therapeutic strategies against obesity and type 2 diabetes

Scheideler, M., Herzig, S., & Georgiadi, A. (2017) · Hormone Molecular Biology and Clinical Investigation · doi:10.1515/hmbci-2017-0043 · Cited by 12

Long non-coding RNA LOC105611671 modulates fibroblast growth factor 9 (FGF9) expression by targeting oar-miR-26a to promote testosterone biosynthesis in Hu sheep

Gao, X., Zhu, M., An, S., Liang, Y., Yang, H., Pang, J., Liu, Z., Zhang, G., & Wang, F. (2019) · Reproduction Fertility and Development · doi:10.1071/rd19116 · Cited by 12

Microbiota-mediated induction of beige adipocytes in response to dietary cues

Tanoue, T., Nagayama, M., Roochana, A., Zimmerman, S. E., Ashenberg, O., Jain, T., Igarashi, R., Sasajima, S., Takeshita, K., Hetherington, N. A., et al. (2026) · Nature · doi:10.1038/s41586-026-10205-3 · Cited by 14

Reduced adiposity attenuates FGF21 mediated metabolic improvements in the Siberian hamster

Lewis, J. E., Samms, R. J., Cooper, S., Luckett, J., Perkins, A. C., Adams, A. C., Tsintzas, K., & Ebling, F. J. P. (2017) · Scientific Reports · doi:10.1038/s41598-017-03607-x · Cited by 11

Post-Exercise Changes of Beta Hydroxybutyrate as a Predictor of Weight Changes

Matoulek, M., Svobodová, Š., VETROVSKA, R., Stránská, Z., & Svacina, S. (2014) · Physiological Research · doi:10.33549/physiolres.932815 · Cited by 11

Myokine Secretion following an Aerobic Exercise Intervention in Individuals with Type 2 Diabetes with or without Exercise Resistance

Garneau, L., Mulvihill, E. E., Smith, S. R., Sparks, L. M., & Aguer, C. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25094889 · Cited by 13

The color of fat and its central role in the development and progression of metabolic diseases

Gaggini, M., Carli, F., & Gastaldelli, A. (2017) · Hormone Molecular Biology and Clinical Investigation · doi:10.1515/hmbci-2017-0060 · Cited by 11

Identification of IQ motif–containing GTPase-activating protein 1 as a regulator of long-term ketosis

Erickson, H. L., & Anakk, S. (2018) · JCI Insight · doi:10.1172/jci.insight.99866 · Cited by 9

Adipose tissue-liver crosstalk during pathologic changes caused by vinyl chloride metabolites in mice

Kaelin, B. R., McKenzie, C. M., Hempel, K. W., Lang, A. L., Arteel, G. E., & Beier, J. I. (2020) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2020.115068 · Cited by 10

Pseudo-Starvation Driven Energy Expenditure Negatively Affects Ovarian Follicle Development

Li, M., Coleman, V., Zhao, Y., Ost, M., Voigt, A., Bunschoten, A., Keijer, J., Teerds, K. J., & Klaus, S. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22073557 · Cited by 10

Fibroblast growth factor‑21 is a potential diagnostic factor for patients with gestational diabetes mellitus

Xu, C., Han, Z., Li, P., & Li, X. (2018) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2018.6291 · Cited by 9

Fibroblast growth factor 21 induces lipolysis more efficiently than it suppresses lipogenesis in goat adipocytes

Zhang, Y., Li, L., Wang, Q., Zhan, S., Wang, L., Zhong, T., Guo, J., & Zhang, H. (2018) · Cytotechnology · doi:10.1007/s10616-018-0237-1 · Cited by 10

The growth factor FGF21 maintains neuromuscular junction through histone deacetylase HDAC4 in denervation-induced skeletal muscle atrophy

Zheng, L., Sasaki, T., Ni, L., Hashidume, T., Kawabe, M., Takahashi, Y., Yamauchi, Y., Shimizu, M., & Sato, R. (2025) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2025.110756 · Cited by 9

Multi-tissue transcriptomic and serum metabolomic assessment reveals systemic implications of acute ozone-induced stress response in male Wistar Kyoto rats

Jackson, T. W., House, J. S., Henriquez, A. R., Schladweiler, M. C. J., Jackson, K. M. P., Fisher, A., Snow, S. J., Alewel, D. I., Motsinger‐Reif, A. A., & Kodavanti, U. P. (2023) · Metabolomics · doi:10.1007/s11306-023-02043-5 · Cited by 8

Plasma FGF21 concentrations, adipose fibroblast growth factor receptor-1 and β-klotho expression decrease with fasting in northern elephant seals

Suzuki, M., Lee, A. Y., Vázquez‐Medina, J. P., Viscarra, J. A., Crocker, D. E., & Ortiz, R. M. (2015) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2015.03.009 · Cited by 8

Fibroblast Growth Factor 23 is Associated With Adiposity in Patients Receiving Hemodialysis: Possible Cross Talk Between Bone and Adipose Tissue

Chiang, J. M., Kaysen, G. A., Schafer, A. L., Delgado, C., & Johansen, K. L. (2018) · Journal of Renal Nutrition · doi:10.1053/j.jrn.2017.12.010 · Cited by 8

Differential effects of protein intake versus intake of a defined oligopeptide on FGF-21 in obese human subjects in vivo

Fangmann, D., Geisler, C., Schlicht, K., Hartmann, K., Köpke, J., Tiede, A., Settgast, U., Türk, K., Schulte, D. M., Altmann, K., et al. (2020) · Clinical Nutrition · doi:10.1016/j.clnu.2020.06.006 · Cited by 8

Resistance to the Beneficial Metabolic Effects and Hepatic Antioxidant Defense Actions of Fibroblast Growth Factor 21 Treatment in Growth Hormone-Overexpressing Transgenic Mice

Boparai, R. K., Arum, O., Miquet, J. G., Masternak, M. M., Bartke, A., & Khardori, R. K. (2015) · International Journal of Endocrinology · doi:10.1155/2015/282375 · Cited by 8

Circulating factors that influence the central nervous system remyelination

Saitoh, S. S., Tanabe, S., & Muramatsu, R. (2022) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2021.12.001 · Cited by 8

Trans‐System Mechanisms Against Ischemic Myocardial Injury

Liu, S. Q., Ma, X., Qin, G., Liu, Q., Li, Y., & Wu, Y. H. (2014) · Comprehensive physiology · doi:10.1002/cphy.c140026 · Cited by 8

Pharmacological but Not Physiological Levels of GDF15 and FGF21 Regulate Body Weight and Glycemic Control in Obese Mice

Engelbeen, S., Jacobsen, J. M., Deisen, L., Parsche, E., Buch-Rasmussen, A. S., Clemmensen, C., Kuhre, R. E., Johann, K., & Kleinert, M. (2025) · The FASEB Journal · doi:10.1096/fj.202501350r · Cited by 8

Pharmacokinetics, tissue distribution, and excretion of FGF‐21 following subcutaneous administration in rats

He, Y., Li, Y., Wei, Z., Zhang, X., Gao, J., Wang, X., Li, X., Wu, W., Li, W., Yi, X., et al. (2018) · Drug Testing and Analysis · doi:10.1002/dta.2365 · Cited by 7

Metformin Does Not Inhibit Exercise-Induced Lipolysis in Adipose Tissue in Young Healthy Lean Men

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Transition Period of the Dairy Cow Revisited: I. Homeorhesis and Its Changes by Selection and Management

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