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Cited by 578

The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.

In Vivo Stimulation of Bone Formation by Transforming Growth Factor-β

NODA, MASAKI, CAMILLIERE, JAMES J.·1989·Endocrinology
DOI 10.1210/endo-124-6-2991
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Abstract

The effect of transforming growth factor-beta (TGF beta) on bone in vivo was examined. Twelve daily injections of 1 microgram TGF beta directly onto the periostea of parietal bones of neonatal rats stimulated the formation of periosteal woven bone. The thickness of the treated parietal bones increased at least 2-fold in a dose-dependent manner. This TGF beta effect was localized at the sites of injection, and no change was observed in contralateral parietal bones and tibiae. The body weight in these growing rats was not affected by TGF beta 1. TGF beta 2 had effects similar to those of TGF beta 1 on the parietal bones in vivo. These results reveal for the first time that TGF beta stimulates bone formation in vivo and indicate its anabolic role in local bone metabolism.

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Metadata

Authors
NODA, M., & CAMILLIERE, J. J.
Venue
Endocrinology
Publisher
The Endocrine Society
Published
1989-06
Volume
124
Issue
6
Pages
2991-2994
ISSN
  • 0013-7227 (ISSN-L)
  • 1945-7170
DOI
10.1210/endo-124-6-2991
OpenAlex
W2059059445
Cited by
578
References
27
FWCI
7.81
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: In Vivo Stimulation of Bone Formation by Transforming Growth Factor-β. https://app.cochat.ai/papers/10.1210/endo-124-6-2991
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NODA, M., & CAMILLIERE, J. J. (1989). In Vivo Stimulation of Bone Formation by Transforming Growth Factor-β. Endocrinology. https://doi.org/10.1210/endo-124-6-2991

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.