Gender differences in large artery stiffness pre-and post puberty
Abstract
Age-related large artery stiffening is more pronounced in women compared with men and is an important cause of isolated systolic hypertension. This study aimed to investigate whether such gender differences are inherent or the result of sex steroid influences. Healthy children prepuberty [26 female (10.3 +/- 0.1 yr), 32 male (10.3 +/- 0.1 yr), mean age +/- SD] and post puberty [30 female (15.9 +/- 0.2 yr), 22 male (15.9 +/- 0.4 yr)] were studied. Large artery stiffness was assessed globally via systemic arterial compliance and regionally via pulse wave velocity. Prepubertal males and females did not differ in body size, cardiac output, or heart rate. Prepubertal females had stiffer large arteries and higher pulse pressure than age-matched males (P < 0.05). Postpubertal males were taller and heavier and had a greater cardiac output and lower heart rate compared with similarly aged females. In relation to pubertal status, females developed more distensible large arteries post puberty whereas males developed stiffer large vessels (P < 0.05). These changes where such that central large artery stiffness was similar between genders in the postpubertal group. Together these data suggest that large artery stiffness varies intrinsically between genders but is also modulated by both male and female sex steroids.
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For females, PWV stayed roughly the same, while there was an increase in PWV for males.
“However, for females, PWV stayed roughly the same, while there was an increase in PWV for males.”
From Sources of inaccuracy in photoplethysmography for continuous cardiovascular monitoring (2021) · cites this paper as [104]
Post-puberty, both males and females have an increase in arterial compliance, determining no gender-dependent differences between the measurement.
“Post-puberty, both males and females have an increase in arterial compliance, determining no gender-dependent differences between the measurement.”
From Sources of inaccuracy in photoplethysmography for continuous cardiovascular monitoring (2021) · cites this paper as [104]
During prepuberty, females have lower arterial compliance and higher central and peripheral PWV yielding stiffer arteries compared to males.
“It was discovered during prepuberty, females have lower arterial compliance and higher central and peripheral PWV yielding stiffer arteries compared to males.”
From Sources of inaccuracy in photoplethysmography for continuous cardiovascular monitoring (2021) · cites this paper as [104]
Cites
Laurent, S., Boutouyrie, P., Asmar, R., Gautier, I., Laloux, B., Guize, L., Ducimetiere, P., & Benetos, A. (2001) · Hypertension · doi:10.1161/01.hyp.37.5.1236 · Cited by 3,856 · see citing works
Burt, V. L., Whelton, P., Roccella, E. J., Brown, C., Cutler, J. A., Higgins, M., Horan, M. J., & Labarthe, D. (1995) · Hypertension · doi:10.1161/01.hyp.25.3.305 · Cited by 2,998 · see citing works
Valery (1995) · doi:10.1001/jama.1995.03520270033028 · Cited by 2,320 · see citing works
Aortic Stiffness Is an Independent Predictor of Primary Coronary Events in Hypertensive Patients
Boutouyrie, P., Tropeano, A., Asmar, R. G., Gautier, I., Bénétos, A., Lacolley, P. J., & Laurent, S. (2002) · Hypertension · doi:10.1161/hy0102.099031 · Cited by 1,745 · see citing works
Estrogen and coronary heart disease in women
Barrett-Connor, E. (1991) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1991.03460140089033 · Cited by 1,241 · see citing works
Cardiovascular Health and Disease in Women
WENGER, N. K., Speroff, L., & Packard, B. (1993) · New England Journal of Medicine · doi:10.1056/nejm199307223290406 · Cited by 801 · see citing works
Caulin‐Glaser, T., García‐Cardeña, G., Sarrel, P. M., Sessa, W. C., & Bender, J. R. (1997) · Circulation Research · doi:10.1161/01.res.81.5.885 · Cited by 472 · see citing works
Chen, C.-H., Ting, C.-T., Nussbacher, A., Nevo, E., Kass, D. A., Pak, P. H., Wang, S.-P., Chang, M.-S., & Yin, F. C. P. (1996) · Hypertension · doi:10.1161/01.hyp.27.2.168 · Cited by 400 · see citing works
Estimation of total arterial compliance: an improved method and evaluation of current methods
Liu, Z., Brin, K. P., & Yin, F. C. P. (1986) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1986.251.3.h588 · Cited by 385 · see citing works
Variations in Endothelial Function and Arterial Compliance during the Menstrual Cycle
Williams, M. R. I., Westerman, R. A., Kingwell, B. A., Paige, J., Blombery, P. A., Sudhir, K., & Komesaroff, P. A. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.11.8013 · Cited by 333 · see citing works
Self-citationExercise training increases total systemic arterial compliance in humans
Cameron, J. D., & Dart, A. M. (1994) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1994.266.2.h693 · Cited by 323 · see citing works
Self-citationSwales, J. D. (1994) · Blackwell Scientific Publications eBooks · Cited by 305 · see citing works
Arterial compliance increases after moderate-intensity cycling
Kingwell, B. A., Berry, K. L., Cameron, J. D., Jennings, G., & Dart, A. M. (1997) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1997.273.5.h2186 · Cited by 286 · see citing works
Self-citationHormonal Therapy Increases Arterial Compliance in Postmenopausal Women
Rajkumar, C., Kingwell, B. A., Cameron, J. D., Waddell, T. K., Mehra, R., Christophidis, N., Komesaroff, P. A., McGrath, B. P., Jennings, G., Sudhir, K., et al. (1997) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(97)00191-5 · Cited by 276 · see citing works
Self-citationDart, A. M., Lacombe, F., Yeoh, J. K., Cameron, J. D., Jennings, G., Laufer, E., & Esmore, D. S. (1991) · The Lancet · doi:10.1016/0140-6736(91)90415-l · Cited by 261 · see citing works
Self-citationMcCrohon, J. A., Jessup, W., Handelsman, D. J., & Celermajer, D. S. (1999) · Circulation · doi:10.1161/01.cir.99.17.2317 · Cited by 242 · see citing works
Salivary Testosterone Determination in Studies of Child Health and Development
Granger, D. A., Schwartz, E. B., Booth, A. D., & Arentz, M. (1999) · Hormones and Behavior · doi:10.1006/hbeh.1998.1492 · Cited by 234 · see citing works
Women exhibit a greater age-related increase in proximal aortic stiffness than men
Waddell, T. K., Dart, A. M., Gatzka, C. D., Cameron, J. D., & Kingwell, B. A. (2001) · Journal of Hypertension · doi:10.1097/00004872-200112000-00014 · Cited by 217 · see citing works
Self-citationEffect of Vasa Vasorum Flow on Structure and Function of the Aorta in Experimental Animals
Stefanadis, C., Vlachopoulos, C. V., Karayannacos, P., Boudoulas, H. K., Stratos, C., Filippides, T., Agapitos, M. V., & TOUTOUZAS, P. K. (1995) · Circulation · doi:10.1161/01.cir.91.10.2669 · Cited by 211 · see citing works
Androgen Deprivation Is Associated With Enhanced Endothelium-Dependent Dilatation in Adult Men
Herman, S. M., Robinson, J. T. C., McCredie, R. J., Adams, M. R., Boyer, M. J., & Celermajer, D. S. (1997) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.17.10.2004 · Cited by 165 · see citing works
Oestradiol inhibits smooth muscle cell proliferation of pig coronary artery
Vargas, R., Wróblewska, B., Rego, A., Hatch, J. D., & Ramwell, P. W. (1993) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1993.tb13616.x · Cited by 163 · see citing works
Lu, Y.-C., Bentley, G. R., Gann, P. H., Hodges, K. R., & Chatterton, R. T. (1999) · Fertility and Sterility · doi:10.1016/s0015-0282(99)00093-x · Cited by 159 · see citing works
Fischer, G. M., & Swain, M. L. (1977) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1977.232.6.h617 · Cited by 158 · see citing works
Gender differences in the regulation of vascular tone
Thompson, J., & Khalil, R. A. (2003) · Clinical and Experimental Pharmacology and Physiology · doi:10.1046/j.1440-1681.2003.03790.x · Cited by 149 · see citing works
Fujimoto, R., Morimoto, I., Morita, E., Sugimoto, H., Ito, Y., & Eto, S. (1994) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(94)90025-6 · Cited by 141 · see citing works
Progesterone receptors in the human heart and great vessels.
Ingegno, M. D., Money, S. R., Thelmo, W., Greene, G. L., Davidian, M., Jaffe, B. M., & Pertschuk, L. P. (1988) · PubMed · Cited by 138 · see citing works
Oestrogen relaxes human epicardial coronary arteries through non-endothelium-dependent mechanisms
Chester, A. H., Jiang, C., Borland, J., Yacoub, M. H., & Collins, P. D. (1995) · Coronary Artery Disease · doi:10.1097/00019501-199505000-00009 · Cited by 121 · see citing works
Reproductive history and cardiovascular disease risk in postmenopausal women
de Kleijn, M. J. J., van der Schouw, Y. T., & van der Graaf, Y. (1999) · Maturitas · doi:10.1016/s0378-5122(99)00038-9 · Cited by 118 · see citing works
Gender Differences in Atherosclerosis
Hayashi, T., Fukuto, J. M., Ignarro, L. J., & Chaudhuri, G. (1995) · Journal of Cardiovascular Pharmacology · doi:10.1097/00005344-199511000-00017 · Cited by 69 · see citing works
Withdrawal of hormonal therapy for 4 weeks decreases arterial compliance in postmenopausal women
Waddell, T. K., Rajkumar, C., Cameron, J. D., Jennings, G., Dart, A. M., & Kingwell, B. A. (1999) · Journal of Hypertension · doi:10.1097/00004872-199917030-00015 · Cited by 69 · see citing works
Self-citationLifetime estrogen exposure versus age at menopause as mortality predictor
Jansen, S. C., Temme, E. H. M., & Schouten, E. G. (2002) · Maturitas · doi:10.1016/s0378-5122(02)00183-4 · Cited by 66 · see citing works
Higashiura, K., Mathur, R. S., & Halushka, P. V. (1997) · Journal of Cardiovascular Pharmacology · doi:10.1097/00005344-199703000-00002 · Cited by 58 · see citing works
Muesing, R. A., Forman, M. R., Graubard, B. I., Beecher, G. R., Lanza, E., McAdam, P. A., Campbell, W. S., & Olson, B. R. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.81.10.8855808 · Cited by 57 · see citing works
Rapid noninvasive measurement of hormones in transdermal exudate and saliva
Cook, C. J. (2002) · Physiology & Behavior · doi:10.1016/s0031-9384(01)00658-8 · Cited by 48 · see citing works
Effects of Estrogen Treatment on Arterial Wall Structure and Function
Clarkson, T. B., Anthony, M. S., & Klein, K. (1994) · Drugs · doi:10.2165/00003495-199400472-00008 · Cited by 45 · see citing works
Oestrogen as a calcium channel blocker
Collins, P. D., Beale, C. M., & Rosano, G. M. C. (1996) · European Heart Journal · doi:10.1093/eurheartj/17.suppl_d.27 · Cited by 43 · see citing works
ESTIMATION OF ARTERIAL MECHANICS IN CLINICAL PRACTICE AND AS A RESEARCH TECHNIQUE
Cameron, J. D. (1999) · Clinical and Experimental Pharmacology and Physiology · doi:10.1046/j.1440-1681.1999.03032.x · Cited by 39 · see citing works
Ba, Z. F. (2001) · Archives of Surgery · doi:10.1001/archsurg.136.10.1158 · Cited by 39 · see citing works
Lin, A., McGill, H. C., & Shain, S. A. (1981) · Circulation Research · doi:10.1161/01.res.49.4.1010 · Cited by 37 · see citing works
Evidence for soluble and nuclear site I binding of estrogens in human aorta
Campisi, D., Cutolo, M., Carruba, G., Casto, M. L., Comito, L., Granata, O. M., Valentino, B., Kings, R. J. B., & CASTAGNETTA, L. A. M. (1993) · Atherosclerosis · doi:10.1016/0021-9150(93)90269-z · Cited by 31 · see citing works
Lin, A., McGill, H. C., & Shain, S. A. (1981) · Arteriosclerosis An Official Journal of the American Heart Association Inc · doi:10.1161/01.atv.1.4.257 · Cited by 23 · see citing works
Effects of Sex Hormones on the Passive Mechanical Properties of Rat Carotid Artery
Cox, R. H., & Fischer, G. M. (2008) · Blood Vessels · doi:10.1159/000158172 · Cited by 18 · see citing works
Sexual dimorphism of binding sites of testosterone and dihydrotestosterone in rabbit model
Teruhiko, T., K.Eisuke, W., NAKAGAWA, M., Misao, R., Itoh, T., Imai, A., & Mori, H. (1993) · Comparative Biochemistry and Physiology Part A Physiology · doi:10.1016/0300-9629(93)90278-c · Cited by 16 · see citing works
Cardiovascular effects of sex hormones
Teede, H. J., & McGrath, B. P. (1999) · Clinical Science · doi:10.1042/cs0970001 · Cited by 10 · see citing works
藤本, 良. (1994) · Medical Entomology and Zoology · doi:10.11501/3106845 · Cited by 10 · see citing works
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1 of the 46 references couldn’t be matched to a known paper.
Cited by
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Recommendations for Improving and Standardizing Vascular Research on Arterial Stiffness
Townsend, R. R., Wilkinson, I. B., Schiffrin, E. L., Avolio, A. P., Chirinos, J. A., Cockcroft, J. R., Heffernan, K. S., Lakatta, E. G., McEniery, C. M., Mitchell, G. F., et al. (2015) · Hypertension · doi:10.1161/hyp.0000000000000033 · Cited by 1,488 · see citing works
Wang (2012) · doi:10.1161/circresaha.111.261388 · Cited by 957 · see citing works
Noninvasive Assessment of Subclinical Atherosclerosis in Children and Adolescents
Urbina, E. M., Williams, R. V., Alpert, B. S., Collins, R. T., Daniels, S. R., Hayman, L. L., Jacobson, M., Mahoney, L. T., Mietus‐Snyder, M., Rocchini, A. P., et al. (2009) · Hypertension · doi:10.1161/hypertensionaha.109.192639 · Cited by 642 · see citing works
Childhood Obesity and Cardiovascular Dysfunction
Coté, A. T., Harris, K. C., Panagiotopoulos, C., Sandor, G. G. S., & Devlin, A. M. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.07.042 · Cited by 456 · see citing works
Sources of inaccuracy in photoplethysmography for continuous cardiovascular monitoring
Fine, J., Branan, K. L., Rodriguez, A. J., Boonya-ananta, T., Ajmal, Ramella-Roman, J. C., McShane, M. J., & Coté, G. L. (2021) · Biosensors · doi:10.3390/bios11040126 · Cited by 348 · see citing works
Jani, B., & Rajkumar, C. (2006) · Postgraduate Medical Journal · doi:10.1136/pgmj.2005.036053 · Cited by 308 · see citing works
Sex differences in mechanisms of arterial stiffness
DuPont, J. J., Kenney, R. M., Patel, A. R., & Jaffe, I. Z. (2019) · British Journal of Pharmacology · doi:10.1111/bph.14624 · Cited by 305 · see citing works
Litwin, M., Diaeresis]hl, E. W., Jourdan, C., Trelewicz, J., Niemirska, A., Fahr, K., Jobs, K., Grenda, R., Wawer, Z. T., Rajszys, P., et al. (2005) · Journal of the American Society of Nephrology · doi:10.1681/asn.2004110932 · Cited by 272 · see citing works
Influence of the Menstrual Cycle, Pregnancy, and Preeclampsia on Arterial Stiffness
Robb, A. O., Mills, N. L., Din, J. N., Smith, I., Paterson, F., Newby, D. E., & Denison, F. C. (2009) · Hypertension · doi:10.1161/hypertensionaha.109.130898 · Cited by 212 · see citing works
Natoli, A. K., Medley, T. L., Ahimastos, A. A., Drew, B. G., Thearle, D. J., Dilley, R. J., & Kingwell, B. A. (2005) · Hypertension · doi:10.1161/01.hyp.0000187016.06549.96 · Cited by 195 · see citing works
Self-citationCardiovascular disease in childhood: the role of obesity
Herouvi, D., Karanasios, E., Karayianni, C., & Karavanaki, K. (2013) · European Journal of Pediatrics · doi:10.1007/s00431-013-1932-8 · Cited by 163 · see citing works
Obesity and Arterial Stiffness in Children
Coté, A. T., Phillips, A. A., Harris, K. C., Sandor, G. G. S., Panagiotopoulos, C., & Devlin, A. M. (2015) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.114.305062 · Cited by 161 · see citing works
Testosterone, cardiovascular disease and the metabolic syndrome
Corona, G., Rastrelli, G., Vignozzi, L., Mannucci, E., & Maggi, M. (2011) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2010.07.002 · Cited by 152 · see citing works
Vascular Stiffness in Aging and Disease
Vatner, S. F., Zhang, J., Vyzas, C., Mishra, K., Graham, R. M., & Vatner, D. E. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.762437 · Cited by 152 · see citing works
Gender differences in artery wall biomechanical properties throughout life
Rossi, P. M., Francès, Y., Kingwell, B. A., & Ahimastos, A. A. (2011) · Journal of Hypertension · doi:10.1097/hjh.0b013e328344da5e · Cited by 137 · see citing works
Self-citationLarge Arterial Elasticity Varies as a Function of Gender and Racism-Related Vigilance in Black Youth
Clark, R., Benkert, R. A., & Flack, J. M. (2006) · Journal of Adolescent Health · doi:10.1016/j.jadohealth.2006.02.012 · Cited by 134 · see citing works
Arterial Stiffness and Its Clinical Implications in Women
Coutinho, T. A. (2014) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2014.03.020 · Cited by 131 · see citing works
Maturation of Cardiovagal Autonomic Function From Childhood to Young Adult Age
Lénárd, Z., Studinger, P., Mersich, B., Kocsis, L., & Kollai, M. (2004) · Circulation · doi:10.1161/01.cir.0000145157.07881.a3 · Cited by 127 · see citing works
Measures of Arterial Stiffness in Youth With Type 1 and Type 2 Diabetes
Wadwa, R. P., Urbina, E. M., Anderson, A., Hamman, R. F., Dolan, L. M., Rodríguez, B. L., Daniels, S. R., Dabelea, D., & for the SEARCH Study Group (2010) · Diabetes Care · doi:10.2337/dc09-0747 · Cited by 120 · see citing works
Thurn, D., Doyon, A., Sözeri, B., Bayazıt, A. K., Canpolat, N., Düzova, A., Querfeld, U., Schmidt, B. M. W., Schaefer, F. S., Wühl, E., et al. (2015) · American Journal of Hypertension · doi:10.1093/ajh/hpv048 · Cited by 119 · see citing works
New insights into arterial stiffening: does sex matter?
Ogola, B. O., Zimmerman, M. A., Clark, G. L., Abshire, C., Gentry, K. M., Miller, K. S., & Lindsey, S. H. (2018) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00132.2018 · Cited by 115 · see citing works
Arterial function in youth: window into cardiovascular risk
Fernhall, B., & Agiovlasitis, S. (2008) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00001.2008 · Cited by 105 · see citing works
Webb, C. M., Elkington, A. G., Kraidly, M., Keenan, N., Pennell, D. J., & Collins, P. D. (2007) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2007.09.114 · Cited by 103 · see citing works
Hidvégi, E. V., Illyés, M., Benczúr, B., Böcskei, R. M., Rátgéber, L., Lenkey, Z., Molnár, F. T., & Cziráki, A. (2012) · Journal of Hypertension · doi:10.1097/hjh.0b013e328359562c · Cited by 97 · see citing works
Effect of single-leg resistance exercise on regional arterial stiffness
Heffernan, K. S., Rossow, L. M., Jae, S. Y., Shokunbi, H. G., Gibson, E. M., & Fernhall, B. (2006) · European Journal of Applied Physiology · doi:10.1007/s00421-006-0259-9 · Cited by 91 · see citing works
Arterial compliance in young children: the role of aerobic fitness
Reed, K. E., Warburton, D. E. R., Lewanczuk, R. Z., Haykowsky, M. J., Scott, J. M., Whitney, C. L., McGavock, J., & McKay, H. A. (2005) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1097/01.hjr.0000176509.84165.3d · Cited by 86 · see citing works
Characteristics of brachial–ankle pulse wave velocity in Japanese children
Niboshi, A., Hamaoka, K., Sakata, K., & Inoue, F. (2006) · European Journal of Pediatrics · doi:10.1007/s00431-006-0135-y · Cited by 83 · see citing works
Lydakis, C., Stefanaki, E., Stefanaki, S., Thalassinos, E., Kavousanaki, M., & Lydaki, D. (2012) · European Journal of Pediatrics · doi:10.1007/s00431-012-1735-3 · Cited by 79 · see citing works
Sarkola, T., Manlhiot, C., Slorach, C., Bradley, T. J., Hui, W., Mertens, L., Redington, A. N., & JAEGGI, E. T. (2012) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.112.252114 · Cited by 77 · see citing works
Serum Testosterone Levels and Arterial Blood Pressure in the Elderly
Fogari, R., Preti, P. S., Zoppi, A., Fogari, E., Rinaldi, A., Corradi, L., & Mugellini, A. (2005) · Hypertension Research · doi:10.1291/hypres.28.625 · Cited by 65 · see citing works
Ambulatory Arterial Stiffness Index Is Increased in Hypertensive Childhood Disease
Simonetti, G. D., von Vigier, R. O., Wühl, E., & Mohaupt, M. G. (2008) · Pediatric Research · doi:10.1203/pdr.0b013e31817d9bc5 · Cited by 63 · see citing works
Altered Endothelial Function in Asymptomatic Male Adolescents with Type 1 Diabetes
Mahmud, F. H., Earing, M. G., Lee, R. A., Lteif, A. N., Driscoll, D. J. O., & Lerman, A. (2006) · Congenital Heart Disease · doi:10.1111/j.1747-0803.2006.00015.x · Cited by 61 · see citing works
Is It Good to Have a Stiff Aorta with Aging? Causes and Consequences
Pierce, G. L., Coutinho, T. A., DuBose, L. E., & Donato, A. J. (2021) · Physiology · doi:10.1152/physiol.00035.2021 · Cited by 64 · see citing works
Karakitsos, D., Patrianakos, A. P., de Groot, E., Boletis, J., Karabinis, A., Kyriazis, J., Samonis, G., Parthenakis, F. I., Vardas, P. E., & Daphnis, E. K. (2006) · American Journal of Nephrology · doi:10.1159/000097816 · Cited by 61 · see citing works
Fhayli, W., Boëté, Q., Harki, O., Briançon‐Marjollet, A., Jacob, M., & Faury, G. (2019) · Matrix Biology · doi:10.1016/j.matbio.2019.08.005 · Cited by 59 · see citing works
Dyslipidemia in Youth with Diabetes: To Treat or Not to Treat?
Maahs, D. M., Wadwa, R. P., Bishop, F. K., Daniels, S. R., Rewers, M., & KLINGENSMITH, G. J. (2008) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2008.05.062 · Cited by 56 · see citing works
Arterial Stiffness and Vascular Load in HFpEF: Differences Among Women and Men
Lau, E. S., Panah, L. G., Zern, E. K., Liu, E. E., Farrell, R., Schoenike, M., Namasivayam, M. J., Churchill, T. W., Curreri, L. A., Malhotra, R. K., et al. (2021) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2021.10.019 · Cited by 55 · see citing works
de Kort, B. J., Koch, S. E., Wissing, T. B., Krebber, M. M., Bouten, C. V. C., & Smits, A. I. P. M. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.113960 · Cited by 58 · see citing works
Central arterial pulse wave augmentation is greater in girls than boys, independent of height
Ayer, J. G., Harmer, J. A., Marks, G. B., Avolio, A. P., & Celermajer, D. S. (2010) · Journal of Hypertension · doi:10.1097/hjh.0b013e3283332286 · Cited by 52 · see citing works
McGreevy, P. D., Righetti, J., & Thomson, P. C. (2005) · Anthrozoös · doi:10.2752/089279305785594045 · Cited by 52 · see citing works
Arterial hypertension in the female world
Dessalvi, C. C., Franconi, F., Cassisa, L., Campesi, I., Pepe, A., Cugusi, L., Maffei, S., Gallina, S., Sciomer, S., & Mercuro, G. (2016) · Journal of Cardiovascular Medicine · doi:10.2459/jcm.0000000000000315 · Cited by 50 · see citing works
Heritability of Arterial Stiffness in Black and White American Youth and Young Adults
Ge, D., Young, T. W., Wang, X., Kapuku, G. K., Treiber, F. A., & Snieder, H. (2007) · American Journal of Hypertension · doi:10.1016/j.amjhyper.2007.05.013 · Cited by 48 · see citing works
Yan, H., Ranadive, S. M., Heffernan, K. S., Lane, A. D., Kappus, R. M., Cook, M. D., Wu, P.-T., Sun, P., Harvey, I. S., Woods, J. A., et al. (2013) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00710.2013 · Cited by 47 · see citing works
Díaz, A., Zócalo, Y., Bia, D., Wray, S. A., & Fischer, E. I. C. (2018) · Journal of Clinical Hypertension · doi:10.1111/jch.13251 · Cited by 42 · see citing works
Coupal, K. E., Heeney, N. D., Hockin, B. C. D., Ronsley, R. J., Armstrong, K. R., Sanatani, S., & Claydon, V. E. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.01197 · Cited by 42 · see citing works
Vascular Ageing in Youth: A Call to Action
Climie, R. E., Park, C. M., Avolio, A. P., Mynard, J. P., Kruger, R., & Bruno, R. M. (2021) · Heart Lung and Circulation · doi:10.1016/j.hlc.2021.06.516 · Cited by 39 · see citing works
Song, B. G., Park, J. B., Cho, S. J., Lee, S. Y., Kim, J. H., Choi, S. M., Park, J. H., Park, Y. H., Choi, J., Lee, S., et al. (2009) · Heart and Vessels · doi:10.1007/s00380-009-1146-1 · Cited by 37 · see citing works
Coovadia, Y., Adler, T. E., Steinback, C. D., Fraser, G. M., & Usselman, C. W. (2020) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00245.2020 · Cited by 37 · see citing works
Can we detect the development of baroreflex sensitivity in humans between 11 and 20 years of age?
Závodná, E., Honzíková, N., Hrstková, H., Nováková, Z., Moudr, J., Jíra, M., & Fišer, B. (2006) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y06-060 · Cited by 35 · see citing works
Carotid arterial stiffness in overweight and obese Indian children
Pandit, D., Kinare, A. S., Chiplonkar, S. A., Khadilkar, A. V., & Khadilkar, V. V. (2011) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem.2011.086 · Cited by 34 · see citing works
A Population-based Study of Arterial Stiffness Index in Relation to Cardiovascular Risk Factors
Sato, H., Hayashi, J., Harashima, K., Shimazu, H., & Kitamoto, K. (2005) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.12.175 · Cited by 34 · see citing works
Koch, S. E., de Kort, B. J., Holshuijsen, N., Brouwer, H. F. M., van der Valk, D. C., Dankers, P. Y. W., van Luijk, J. A. K. R., Hooijmans, C. R., de Vries, R. B. M., Bouten, C. V. C., et al. (2022) · npj Regenerative Medicine · doi:10.1038/s41536-022-00211-0 · Cited by 33 · see citing works
Exposure to metal mixtures in relation to blood pressure among children 5–7 years old
Shih, Y.-H., Howe, C. G., Bryan, M. S., Shahriar, H., Kibriya, M. G., Jasmine, F., Sarwar, G., Graziano, J. H., Persky, V., Jackson, B. P., et al. (2021) · Environmental Epidemiology · doi:10.1097/ee9.0000000000000135 · Cited by 32 · see citing works
Manrique, C. M., Lastra, G., Ramirez‐Perez, F. I., Haertling, D., DeMarco, V. G., Aroor, A. R., Jia, G., Chen, D., Barron, B. J., Garro, M., et al. (2016) · Endocrinology · doi:10.1210/en.2015-1681 · Cited by 28 · see citing works
Insight into the dicrotic notch in photoplethysmographic pulses from the finger tip of young adults
Shi, P. A., Hu, S., Zhu, Y. J., Zheng, J., Qiu, Y., & Cheang, P.-Y. (2009) · Journal of Medical Engineering & Technology · doi:10.3109/03091900903150980 · Cited by 27 · see citing works
Reliability of oscillometric central blood pressure and wave reflection readings
Young, Y., Abdolhosseini, P., Brown, F. C. W., Faulkner, J., Lambrick, D., Williams, M. A., & Stoner, L. R. (2015) · Journal of Hypertension · doi:10.1097/hjh.0000000000000604 · Cited by 25 · see citing works
Testosterone and coronary artery disease in men
Webb, C. M., & Collins, P. D. (2010) · Maturitas · doi:10.1016/j.maturitas.2010.03.029 · Cited by 25 · see citing works
Sex-Specific Impacts of Exercise on Cardiovascular Remodeling
Islam, R. A., Khalsa, S. S. S., Vyas, A. K., & Rahimian, R. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10173833 · Cited by 24 · see citing works
Predictors and Reference Values of Pulse Wave Velocity in Prepubertal Angolan Children
Silva, A. B. T., Capingana, D. P., Magalhães, P., Molina, M. D. C. B., Baldo, M. P., & Mill, J. G. (2015) · Journal of Clinical Hypertension · doi:10.1111/jch.12739 · Cited by 24 · see citing works
Agbaje, A. O., Zachariah, J. P. V., Bamsa, O., Odili, A. N., & Tuomainen, T. (2023) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00008.2023 · Cited by 23 · see citing works
Melo, X., Fernhall, B., Santos, D. A., Pinto, R., Pimenta, N. M., Sardinha, L. B., & Clara, S. (2015) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2015-0204 · Cited by 23 · see citing works
Intima-media thickness and arterial function in obese and non-obese children
Weberruß, H., Pirzer, R., Böhm, B., Pozza, R. D., Netz, H., & Oberhoffer, R. (2015) · BMC Obesity · doi:10.1186/s40608-016-0081-9 · Cited by 22 · see citing works
Barba, G., Casullo, C., Russo, M. D., Russo, P., Nappo, A., Lauria, F., & Siani, A. (2008) · American Journal of Hypertension · doi:10.1038/ajh.2008.228 · Cited by 23 · see citing works
Ganti, V. G., Carek, A. M., Jung, H., Srivatsa, A. V., Cherry, D., Johnson, L. N., & Inan, O. T. (2021) · JMIR mhealth and uhealth · doi:10.2196/27466 · Cited by 22 · see citing works
Noninvasive measures of vascular health are reliable in preschool-aged children
Currie, K. D., Proudfoot, N. A., Timmons, B. W., & MacDonald, M. J. (2010) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/h10-037 · Cited by 22 · see citing works
Walker, D. J., MacIntosh, A., Kozyrskyj, A. L., Becker, A. B., & McGavock, J. (2013) · Journal of Physical Activity and Health · doi:10.1123/jpah.10.2.198 · Cited by 22 · see citing works
Ventricular-arterial coupling: changes with ageing and implications across cardiovascular conditions
Gaczoł, M., Rajzer, M. W., & Wojciechowska, W. (2025) · Blood Pressure · doi:10.1080/08037051.2025.2457698 · Cited by 21 · see citing works
Establishing Reference Values for Pulse Wave Velocity in Young People: The Youth Vascular Consortium
Kodithuwakku, V., Breslin, M. C., Hersant, J., Bruno, R. M., Boutouyrie, P., Urbina, E. M., Gall, S., Climie, R. E., Hidvégi, E. V., Cziráki, A., et al. (2025) · Hypertension · doi:10.1161/hypertensionaha.125.25007 · Cited by 21 · see citing works
Reduced arterial stiffness in very fit boys and girls
Weberruß, H., Pirzer, R., Schulz, T., Böhm, B., Pozza, R. D., Netz, H., & Oberhoffer, R. (2016) · Cardiology in the Young · doi:10.1017/s1047951116000226 · Cited by 21 · see citing works
Arterial Stiffness in Transgender Men Receiving Long-term Testosterone Therapy
Cunha, F. S., Bachega, T. A. S. S., Costa, E. M. F., Brito, V. N., Alvares, L. A. M., Costa‐Hong, V., Verardino, R. G. S., Sircili, M. H. P., Mendonca, B. B., Bortolotto, L. A., et al. (2023) · Journal of the Endocrine Society · doi:10.1210/jendso/bvad040 · Cited by 20 · see citing works
Increased Arterial Stiffness in Adolescents With Obesity
Lentferink, Y. E., Kromwijk, L. A. J., van der Aa, M. P., Knibbe, C. A. J., & van der Vorst, M. M. J. (2019) · Global Pediatric Health · doi:10.1177/2333794x19831297 · Cited by 20 · see citing works
Influence of Cardiovascular Risk Factors on Total Arterial Compliance
Haluska, B. A., Jeffriess, L., Downey, M., CARLIER, S. G., & Marwick, T. H. (2007) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2007.05.043 · Cited by 20 · see citing works
Sex and gender differences during the lung lifespan: unveiling a pivotal impact
Tondo, P., Meschi, C., Mantero, M., Scioscia, G., Siciliano, M., Bradicich, M., & Stella, G. M. (2025) · European Respiratory Review · doi:10.1183/16000617.0121-2024 · Cited by 19 · see citing works
Overweight and obese children with sleep disordered breathing have elevated arterial stiffness
Walter, L. M., Tamanyan, K., Limawan, A. P., Biggs, S. N., Weichard, A. J., Davey, M. J., Nixon, G. M., & Horne, R. S. C. (2018) · Sleep Medicine · doi:10.1016/j.sleep.2018.05.007 · Cited by 19 · see citing works
Tai, C.-C., Chen, Y., Kalfiřt, L., Masodsai, K., Su, C., & Yang, A. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19063206 · Cited by 23 · see citing works
Urbina, E. M., Bean, J. A., Daniels, S. R., D’Alessio, D. A., & Dolan, L. M. (2007) · Journal of the American Society of Hypertension · doi:10.1016/j.jash.2007.01.008 · Cited by 19 · see citing works
The association between arterial properties and blood pressure in children
Phillips, A. A., Chirico, D., Coverdale, N. S., Fitzgibbon‐Collins, L. K., Shoemaker, J. K., Wade, T. J., Cairney, J., & O’Leary, D. D. (2014) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2014-0206 · Cited by 18 · see citing works
Arterial stiffness in junior high school students: Longitudinal observations
Fujiwara, H., Nakajima, H., Inoue, F., Kosaka, K., Asano, H., & Yoshii, K. (2017) · Pediatrics International · doi:10.1111/ped.13475 · Cited by 18 · see citing works
The Effects of Sex and Pubertal Maturation on Cardiovagal Baroreflex Sensitivity
Chirico, D., Liu, J., Klentrou, P., Shoemaker, J. K., & O’Leary, D. D. (2015) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2015.07.054 · Cited by 17 · see citing works
Nowak, K. L., Farmer‐Bailey, H., Cadnapaphornchai, M. A., You, Z., George, D. M., Wang, W., Jovanovich, A. J., Soranno, D. E., Gitomer, B. Y., & Chonchol, M. (2020) · Contemporary Clinical Trials Communications · doi:10.1016/j.conctc.2020.100635 · Cited by 17 · see citing works
Jimenez, V., Sánchez, N., Clark, E. L. M., Miller, R. L., Casamassima, M., VERROS, M. M., Conte, I., Ruiz-Jaquez, M. J., Gulley, L. D., Johnson, S. A., et al. (2021) · Developmental Psychobiology · doi:10.1002/dev.22127 · Cited by 18 · see citing works
Arterial stiffness in childhood: A predictor for later cardiovascular disease?
Ahmadizar, F., & Voortman, T. (2017) · European Journal of Preventive Cardiology · doi:10.1177/2047487317743046 · Cited by 17 · see citing works
Mechanisms of Sex Disparities in Cardiovascular Function and Remodeling
Chaudhari, S. K., Cushen, S. C., Osikoya, O., Jaini, P. A., Posey, R., Mathis, K. W., & Goulopoulou, S. (2018) · Comprehensive physiology · doi:10.1002/cphy.c180003 · Cited by 16 · see citing works
Gender is a determinant of carotid artery stiffness independent of age and blood pressure
Wang, Z., Li, W., Liu, W., & Tian, J. (2021) · British Journal of Radiology · doi:10.1259/bjr.20200796 · Cited by 15 · see citing works
Burden, S. J., Alshehri, R., Lamata, P., Poston, L., & Taylor, P. D. (2024) · International Journal of Obesity · doi:10.1038/s41366-024-01536-0 · Cited by 15 · see citing works
Jackson, D. N., Ellis, C. G., & Shoemaker, J. K. (2010) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00420.2009 · Cited by 15 · see citing works
Al‐Naamani, N., Chirinos, J. A., Zamani, P. L., Ruthazer, R., Paulus, J. K., Roberts, K. E., Barr, R. G., Lima, J. A. C., Bluemke, D. A., Kronmal, R. A., et al. (2016) · Journal of the American Heart Association · doi:10.1161/jaha.116.004162 · Cited by 15 · see citing works
Mihuţa, M. S., Paul, C., Borlea, A., Cepeha, C. M., Velea, I. P., Mozos, I. M., & Stoian, D. L. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11175078 · Cited by 14 · see citing works
Sex differences in aortic augmentation index in adolescents
Barraclough, J., Garden, F. L., Toelle, B. G., O’Meagher, S., Marks, G. B., Cowell, C. T. C. T., Celermajer, D. S., & Ayer, J. G. (2017) · Journal of Hypertension · doi:10.1097/hjh.0000000000001425 · Cited by 14 · see citing works
Enéa, C., Laffetas, P., Pichon, A., & Delpech, N. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18073393 · Cited by 14 · see citing works
Mihuţa, M. S., Paul, C., Borlea, A., Roi, C. M., Velea-Barta, O.-A., Mozos, I. M., & Stoian, D. L. (2023) · Biomedicines · doi:10.3390/biomedicines11071841 · Cited by 14 · see citing works
Arterial distensibility is reduced in overweight pre- and early pubescent children
Banach, A. M., Peralta-Huertas, J., Livingstone, K., Petrella, N. J., Klentrou, P., Faught, B. E., Wade, T. J., & O’Leary, D. D. (2009) · European Journal of Pediatrics · doi:10.1007/s00431-009-1092-z · Cited by 14 · see citing works
Sex differences in genetic and environmental determinants of pulse pressure
Scurrah, K. J., Byrnes, G. B., Hopper, J. L., & Harrap, S. B. (2006) · Genetic Epidemiology · doi:10.1002/gepi.20156 · Cited by 14 · see citing works
Pediatric reference values for arterial stiffness parameters cardio-ankle vascular index and CAVI0
Jurko, T., Mestanik, M., Jurko, A., Spronck, B., Avolio, A. P., Mestanikova, A., Sekaninova, N., & Tonhajzerová, I. (2018) · Journal of the American Society of Hypertension · doi:10.1016/j.jash.2018.10.003 · Cited by 13 · see citing works
Arterial stiffness in children with and without probable developmental coordination disorder
Philips, N. E., Chirico, D., Cairney, J., Hay, J., Faught, B. E., & O’Leary, D. D. (2016) · Research in Developmental Disabilities · doi:10.1016/j.ridd.2016.07.011 · Cited by 13 · see citing works
Virag, L., Wilson, J. S., Humphrey, J. D., & Karšaj, I. (2017) · International Journal for Numerical Methods in Biomedical Engineering · doi:10.1002/cnm.2893 · Cited by 13 · see citing works
Effect of maturational status and training on upper limb pulse wave velocity
Vinet, A., NOTTIN, S. P., Beck, L., Pérez‐Martin, A., Dauzat, M., & Obert, P. (2004) · European Journal of Pediatrics · doi:10.1007/s00431-004-1585-8 · Cited by 12 · see citing works
Urbina, E. M., Khoury, P. R., Martin, L. J., D’Alessio, D. A., & Dolan, L. M. (2009) · International Journal of Obesity · doi:10.1038/ijo.2009.164 · Cited by 12 · see citing works
Weight reduction and aortic stiffness in obese children and adolescents: a 1-year follow-up study
Hvidt, K. N., Olsen, M. H., Ibsen, H., & Holm, J.-C. (2015) · Journal of Human Hypertension · doi:10.1038/jhh.2014.127 · Cited by 12 · see citing works
Connecting Aortic Stiffness to Vascular Contraction: Does Sex Matter?
de Oliveira, A. A., Priviero, F. B. M., Delgado, A. I., Dong, P., Mendoza, V. O., Gu, L., Webb, R. C., & Nunes, K. P. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231911314 · Cited by 11 · see citing works
- Authors
- Ahimastos, A. A., Formosa, M., Dart, A. M., & Kingwell, B. A.
- Affiliations
- Baker Heart and Diabetes Institute (AU)
- Corresponding author
- Kingwell, Bronwyn A.
- Venue
- The Journal of Clinical Endocrinology & Metabolism
- Publisher
- The Endocrine Society
- Published
- 2003-11-01
- Volume
- 88
- Issue
- 11
- Pages
- 5375-5380
- ISSN
- 0021-972X (ISSN-L)
- 1945-7197
- OpenAlex
- W2083745787
- Cited by
- 196
- References
- 46
- Citations by year
- 2026: 5 · 2025: 10 · 2024: 3 · 2023: 11 · 2022: 12 · 2021: 19 · 2020: 7 · 2019: 7 · 2018: 7 · 2017: 7 · 2016: 9 · 2015: 14 · 2014: 8 · 2013: 15 · 2012: 10
- FWCI
- 3.95
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Heart Foundation of Australia
- Heart Research Institute
- Medical Research Council
- National Health and Medical Research Council
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Physical Sciences › Engineering › Biomedical Engineering › Elasticity and Material Modeling
- Keywords
- large artery stiffness, sex differences, puberty, sex steroids, pulse wave velocity, arterial compliance, pulse pressure, isolated systolic hypertension, children, adolescents, cardiac output, heart rate
- MeSH terms
- Adolescent, Age Factors, Blood Pressure, Brachial Artery, Child, Compliance, Estradiol, Female, Humans, Male, Puberty, Pulsatile Flow, Saliva, Sex Characteristics, Testosterone
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