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Long-Term Testosterone Gel (AndroGel) Treatment Maintains Beneficial Effects on Sexual Function and Mood, Lean and Fat Mass, and Bone Mineral Density in Hypogonadal Men
Abstract
Transdermal testosterone (T) delivery represents an effective alternative to injectable androgens. We studied 163 hypogonadal men who applied 5, 7.5, or 10 g AndroGel (T gel) 1% CIII per day for up to 42 months. Efficacy data were presented in 123 subjects considered evaluable. Continuous AndroGel treatment normalized mean serum T and free T levels. Mean serum 5alpha-dihydrotestosterone concentrations and 5alpha-dihydrotestosterone/T ratio slightly increased, mean serum estradiol/T ratio doubled, and mean serum FSH and LH levels were suppressed by T replacement. Sexual function and mood parameters improved rapidly and were maintained throughout T treatment. Lean body mass increased (P = 0.0001) and fat mass decreased (P = 0.0001), and these changes were maintained with treatment but were not accompanied by significant increases in muscle strength. Increases in serum bone markers suggestive of increased bone formation were followed by gradual and progressive increases in bone mineral density more in the spine (P = 0.0001) than the hip (P = 0.0004). Mild local skin irritation occurred in 12 subjects, resulting in discontinuation in only one subject. Except for the anticipated increase in hematocrit and hemoglobin, there were no clinically significant changes in blood counts or biochemistry. In three subjects with elevated serum prostate-specific antigen, prostate biopsies showed cancer. We conclude that continued application of AndroGel resulted in beneficial effects similar to those with injectables and other transdermal preparations. This study was neither placebo controlled nor powered to determine the effects of T treatment on prostate cancer risk. Thus, monitoring for prostatic disease and assessment for erythrocytosis are strongly advised to reduce the risk of adverse events with T treatment of hypogonadal men.
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“Treatment increases BMD (132-135) and improves trabecular structure (136) and bone mechanical properties (137).”
From Hormonal Replacement in Hypopituitarism in Adults: An Endocrine Society Clinical Practice Guideline (2016) · cites this paper as [137]
In the citing paper
“Prostate-specific antigen and volume rise, marginally, plateauing at 12 months; further increase should be related to aging rather than therapy.”
From Onset of effects of testosterone treatment and time span until maximum effects are achieved (2011) · cites this paper as [87]
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“In a study of 123 subjects over 42 months of testosterone gel application, there was significant increase in serum PSA over the first 6 months and then no further significant increases with continued testosterone treatment was found (87).”
From Onset of effects of testosterone treatment and time span until maximum effects are achieved (2011) · cites this paper as [87]
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Citations
Cites
The Influence of Finasteride on the Development of Prostate Cancer
Thompson, I. M., Goodman, P. J., Tangen, C. M., Lucia, M. S., Miller, G. J., Ford, L. G., Lieber, M. M., Cespedes, R. D., Atkins, J. N., Lippman, S. M., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa030660 · Cited by 2,588
Estrogen Resistance Caused by a Mutation in the Estrogen-Receptor Gene in a Man
Smith, E. P., Boyd, J., Frank, G. R., Takahashi, H., Cohen, R. M., Specker, B., Williams, T. C., Lubahn, D. B., & Korach, K. S. (1994) · New England Journal of Medicine · doi:10.1056/nejm199410203311604 · Cited by 2,471
The Influence of Finasteride on the Development of Prostate Cancer
Sathianathen, N. J. (2021) · Oxford University Press eBooks · doi:10.1093/med/9780190655341.003.0002 · Cited by 2,082
Morishima, A., Grumbach, M. M., Simpson, E. R., Fisher, C., & Qin, K. (1995) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.80.12.8530621 · Cited by 1,416
Effect of testosterone and estradiol in a man with aromatase deficiency
Carani, C., Qin, K., Simoni, M., Faustini-Fustini, M., Serpente, S., Boyd, J., Korach, K. S., & Simpson, E. R. (1997) · New England Journal of Medicine · doi:10.1056/nejm199707103370204 · Cited by 1,151
Testosterone dose-response relationships in healthy young men
Bhasin, S., Woodhouse, L., Casaburi, R., Singh, A. B., Bhasin, D., Berman, N., Chen, X., Yarasheski, K. E., Magliano, L., Dzekov, C., et al. (2001) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2001.281.6.e1172 · Cited by 967
Self-citationKatznelson, L., Finkelstein, J. S., Schoenfeld, D. A., Rosenthal, D. I., Anderson, E. J., & Klibanski, A. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.81.12.8954042 · Cited by 791
Effects of Testosterone Replacement in Hypogonadal Men1
Snyder, P. J., Peachey, H., Berlin, J. A., Hannoush, P., Haddad, G., Dlewati, A., Santanna, J., Loh, L., Lenrow, D. A., Holmes, J. H., et al. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.8.6731 · Cited by 610
Self-citationTestosterone Replacement Increases Fat-Free Mass and Muscle Size in Hypogonadal Men
Bhasin, S., Storer, T. W., Berman, N., Yarasheski, K. E., Clevenger, B., Phillips, J., Lee, W. P., Bunnell, T. J., & Casaburi, R. H. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.2.3733 · Cited by 596
Long-term effect of testosterone therapy on bone mineral density in hypogonadal men
Behre, H. M., Kliesch, S., Leifke, E., Link, T. M., & Nieschlag, E. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.8.4163 · Cited by 559
Cited by
Sorted by citations
Items 501–600 of 655
Nieschlag, E., & Behre, H. M. (2023) · Springer Reference Medizin · doi:10.1007/978-3-662-61901-8_36 · Cited by 2
Effects of testosterone deficiency and therapy on the cardiometabolic syndrome in men
Saad, F., & Traish, A. M. (2025) · The American Journal of the Medical Sciences · doi:10.1016/j.amjms.2025.08.004 · Cited by 2
Androgens: Pharmacological Use and Abuse ☆
Byrne, M. M., & Nieschlag, E. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809324-5.03356-3 · Cited by 2
The interplay between neuroendocrine and sleep alterations following traumatic brain injury
Howell, S., & Griesbach, G. S. (2018) · Neurorehabilitation · doi:10.3233/nre-182483 · Cited by 2
Testosterone - Functions, Uses, Deficiencies, and Substitution
Doi, H. (2022) · IntechOpen eBooks · doi:10.5772/intechopen.102212 · Cited by 2
Testosterone Therapy: Transdermal Androgens
Čeponis, J., Yuen, F., Swerdloff, R. S., & Wang, C. (2023) · Springer eBooks · doi:10.1007/978-3-031-31501-5_14 · Cited by 2
Self-citationJensen, K. H. R., Aarestrup, M. R., Larsen, S. V., Köhler‐Forsberg, K., Knudsen, G. M., Jørgensen, M. B., & Frøkjær, V. G. (2024) · Neuroscience Applied · doi:10.1016/j.nsa.2024.104050 · Cited by 3
Risk of Therapeutic Failure due to Ineffectiveness of Medication
Woring, V. E. (2011) · NASA STI Repository (National Aeronautics and Space Administration) · Cited by 2
Androgen Replacement Therapy in Hypogonadal Men
Čeponis, J., Swerdloff, R. S., & Wang, C. (2017) · Springer eBooks · doi:10.1007/978-3-319-53298-1_18 · Cited by 2
Self-citationTestosterone Replacement Therapy in Men with Prostate Cancer after Proton Therapy
Bryant, C., Hoppe, B. S., Mendenhall, N. P., Henderson, R. H., Nichols, R. C., Morris, C. G., WILLIAMS, C. R., Harris, S. E., Su, Z., Li, Z., et al. (2014) · International Journal of Particle Therapy · doi:10.14338/ijpt-14-00004.1 · Cited by 2
Management of Erectile Dysfunction With Hypogonadism
Liu, C., Huang, S., Wu, W., Lee, Y., & Wang, C. (2010) · Urological Science · doi:10.1016/s1879-5226(10)60025-5 · Cited by 2
Self-citationTostain, J.-B., & Coeuret, C. (2008) · The French Journal of Urology · doi:10.1016/j.purol.2008.06.008 · Cited by 2
Diagnosi e terapia dell’ipogonadismo nella sindrome di Kallmann
Sinisi, A. A., Maione, L., Bellastella, G., Asci, R., & Bellastella, A. (2011) · L Endocrinologo · doi:10.1007/bf03344775 · Cited by 2
Bhasin, S., Cunningham, G. R., Hayes, F. J., Matsumoto, A. M., Snyder, P. J., Swerdloff, R. S., & Montori, V. M. (2010) · Cited by 2
Self-citation[Androgens and prostate: basic research and clinical data].
Pm, M., Rossi, D., Muracciole, X., SAUSSINE, C., Raynaud, J., & Tostain, J.-B. (2004) · PubMed · Cited by 2
Health consequences of ecogenetic variation
Bamshad, M. J., & Motulsky, A. G. (2007) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780199207466.003.0004 · Cited by 2
Morgado, A., Moura, M. L., Dinis, P., & Silva, C. (2019) · International Journal of Impotence Research · doi:10.1038/s41443-019-0169-0 · Cited by 2
Choong, K. L. M., Jasuja, R., Basaria, S. S., Storer, T. W., & Bhasin, S. (2010) · Endocrine updates · doi:10.1007/978-1-4419-7014-5_9 · Cited by 2
CHRONIC HYPOPITUITARISM AFTER TRAUMATIC BRAIN INJURY
Bavisetty, S., Bavisetty, S., McArthur, D. L., Dusick, J. R., Wang, C., Cohan, P., Boscardin, W. J., Swerdloff, R. S., Levin, H. S., Chang, D. J., et al. (2008) · Neurosurgery · doi:10.1227/01.neu.0000313577.16309.cd · Cited by 5
Self-citationAydoğan, Ü., Doğaner, Y. Ç., Haymana, C., Kaplan, U., Aydoğdu, A., Demirci, İ., Meriç, C., & Sönmez, A. (2022) · Archives of Endocrinology and Metabolism · doi:10.20945/2359-3997000000539 · Cited by 2
Topical Testosterone Gel for the Treatment of Male Hypogonadism
Udeoji, D. U., Phan, A., Katsiyiannis, P., Willix, R., & Schwarz, E. R. (2012) · Clinical Medicine Insights Therapeutics · doi:10.4137/cmt.s7348 · Cited by 2
Gonadal hormones and their influence on skeletal health in men
Meier, C., & KRAENZLIN, M. E. (2007) · The Journal of Men s Health and Gender · doi:10.1016/j.jmhg.2006.06.007 · Cited by 2
Testosterone Therapy: Transdermal Androgens
Čeponis, J., Yadav, P. K., Swerdloff, R. S., & Wang, C. (2017) · Springer eBooks · doi:10.1007/978-3-319-46086-4_11 · Cited by 3
Self-citationHuman Immunodeficiency Virus and Hypogonadal Bone Disease
Miller, M. G., & Mulligan, T. (2005) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1592/phco.25.4.632.61027 · Cited by 2
A Clinical Paradigm for the Combined Management of Androgen Insufficiency and Erectile Dysfunction
Goldstein, I. (2007) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2007.02.002 · Cited by 2
Evolutionary origins of diversity in human viruses
Sharp, P. M., Bailes, E., & Wain, L. V. (2007) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780199207466.003.0013 · Cited by 2
Sex Steroids and Skeletal Health in Men
Meier, C., Liu, P. Y., Seibel, M. J., & Handelsman, D. J. (2006) · Elsevier eBooks · doi:10.1016/b978-0-323-03437-1.50023-3 · Cited by 2
Transdermal Testosterone Gel Treatment of Hypogonadal Men
Han, T. S., & Bouloux, P. M. (2008) · Aging Health · doi:10.2217/1745509x.4.5.517 · Cited by 1
Benefits and Risks of Testosterone Therapy in Men With Testosterone Deficiency
Traish, A. M., & Morgentaler, A. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813197-8.00018-x · Cited by 2
Bathina, S., Prado, M., Lopez, V. F., Colleluori, G., Aguirre, L. E., Chen, R., Villareal, D. T., & Armamento‐Villareal, R. (2025) · Biomolecules · doi:10.3390/biom15010079 · Cited by 1
Impact of Testosterone Deficiency and Testosterone Therapy on Men’s Health
Traish, A. M. (2025) · Springer eBooks · doi:10.1007/978-3-031-89650-7_13 · Cited by 1
Neuroendocrine dysfunction after TBI: A guide for the clinical neuropsychologist
Howell, S., & Masel, B. E. (2025) · The Clinical Neuropsychologist · doi:10.1080/13854046.2025.2537335 · Cited by 1
Psychological and Behavioral Effects of Testosterone
Anawalt, B. D. (2025) · Springer eBooks · doi:10.1007/978-3-031-96376-6_23 · Cited by 1
Methods of correction of hypogonadism syndrome in men and long-term results of drug treatment
Романовна, Р. Е., Rozhivanov, R. V., Морозова, Е. В., Gaidaichuk, K. E., Mel'nichenko, G. A., Andreeva, E. N., & Mokrysheva, N. G. (2025) · Bulletin of Reproductive Health · doi:10.14341/brh12770 · Cited by 1
Nuovi aspetti dell’ipogonadismo maschile: l’ipogonadismo età-correlato (LOH)
Martino, M. U. D., Frajese, G. V., Moretti, C., Frajese, G., & Fabbri, A. (2005) · L Endocrinologo · doi:10.1007/bf03344528 · Cited by 1
Zheng, R., Zhao, Y., Gong, L., Wang, Y., Xu, K., & Gao, Y. (2026) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2026.178611 · Cited by 1
Biomarkers of Cardiovascular Aging
Neki, N. S., Tappia, P. S., & Dhalla, N. S. (2014) · Springer eBooks · doi:10.1007/978-1-4939-0268-2_20 · Cited by 1
Testosterone Therapy for Osteoporosis in Men
Lakshman, K. M., Bhasin, S., & Araujo, A. B. (2010) · Osteoporosis in Men · doi:10.1016/b978-0-12-374602-3.00056-0 · Cited by 1
Testosterone and Cardiovascular Disease in Men
Rothman, M. S., & Wierman, M. E. (2007) · Aging Health · doi:10.2217/1745509x.3.3.375 · Cited by 3
Lipid profile modifications in post-menopausal women treated with testosterone gel
Fernández-Carvajal, J., Luz-Araujo, H., Guerra-Velásquez, M., Reyna‐Villasmil, E., Santos-Bolívar, J., Torres-Cepeda, D., Mejía-Montilla, J., & Reyna-Villasmil, N. (2012) · Endocrinología y Nutrición (English Edition) · doi:10.1016/j.endoen.2011.07.009 · Cited by 1
Tolrà, J. R., Barreda, J. T., García, A. D., Pérez, D. R., & Miranda, E. F. (2010) · Revista Internacional de Andrología · doi:10.1016/s1698-031x(10)70015-7 · Cited by 1
Traitement androgénique des hypoandrismes masculins
Kuhn, J., & Prévost, G. (2013) · La Presse Médicale · doi:10.1016/j.lpm.2013.06.021 · Cited by 1
Modificaciones del perfil lipídico en menopáusicas tratadas con gel de testosterona
Fernández-Carvajal, J., Luz-Araujo, H., Guerra-Velásquez, M., Reyna‐Villasmil, E., Santos-Bolívar, J., Torres-Cepeda, D., Mejía-Montilla, J., & Reyna-Villasmil, N. (2011) · Endocrinología y Nutrición · doi:10.1016/j.endonu.2011.07.010 · Cited by 1
Testosterone replacement therapy after prostate cancer
Coward, R. M., & Carson, C. C. (2011) · Trends in Urology & Men s Health · doi:10.1002/tre.178 · Cited by 1
Testosterone replacement therapy: Take an informed, individualized approach
Coplan, B. H., Spiegel, J. J., Bleaman, I., & Roch, J. (2011) · JAAPA · doi:10.1097/01720610-201101000-00009 · Cited by 1
[Androgens, skeletal muscle and muscle exercise].
Chatard, J., Duclos, M., Rossi, D., & Tostain, J.-B. (2004) · PubMed · Cited by 1
Zhang, Y. (2019) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/bmx8-2852 · Cited by 1
Diabetes mellitus and sarcopenia
Lee, P., & Tan, M. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-820605-8.00009-7 · Cited by 1
Testosterone therapy in prostate cancer: is it still a controversy?
Bart, A. S., Hoof, A. V., Badre-Hume, R., Selvarajah, J., Robillard, K., & Albala, D. M. (2022) · Current Opinion in Urology · doi:10.1097/mou.0000000000001039 · Cited by 1
Li, J., Jiang, Y., Wei, X., Liu, L., Yu, H., Zhang, X., Ye, X., Miao, J., Liu, J., Chen, Y., et al. (2023) · Regenerative Medicine · doi:10.2217/rme-2022-0191 · Cited by 1
Nieschlag, E., & Behre, H. M. (2023) · Springer eBooks · doi:10.1007/978-3-031-31574-9_36 · Cited by 1
Treatment of Hypogonadism in Men
Mehta, A., Paduch, D. A., & Goldstein, M. (2012) · Springer eBooks · doi:10.1007/978-1-4471-4405-2_5 · Cited by 1
[Action of androgens on fat distribution and metabolic balance].
Tostain, J.-B., Heim, M., & Rossi, D. (2004) · PubMed · Cited by 1
Wang, K., Chen, X., Cheng, T. D., Qiu, P., Bird, V. Y., & Prosperi, M. (2019) · Hormones and Cancer · doi:10.1007/s12672-019-00369-y · Cited by 1
Age-Related Testosterone Deficiency Merits Treatment
Traish, A. M. (2021) · Androgens Clinical Research and Therapeutics · doi:10.1089/andro.2020.0019 · Cited by 2
Miedany, Y. M. E. (2022) · Springer eBooks · doi:10.1007/978-3-030-87950-1_3 · Cited by 1
Gibt es eine Pharmakotherapie bei Libidostörungen des Mannes?
Köhn, F. ‐. (2006) · Der Urologe · doi:10.1007/s00120-006-1126-3 · Cited by 1
Dawson, A. W. (2011) · MOspace Institutional Repository (University of Missouri) · Cited by 1
Kallmann Syndrome : Clinical and molecular genetic features in Finland
Laitinen, E. (2012) · Työväentutkimus Vuosikirja · Cited by 1
Male hormonal contraceptives: a potentially patentable and profitable product
Cornia, P. B., & Anawalt, B. D. (2005) · Expert Opinion on Therapeutic Patents · doi:10.1517/13543776.15.12.1727 · Cited by 1
Cornia, P. B., & Anawalt, B. D. (2004) · Expert Opinion on Emerging Drugs · doi:10.1517/14728214.9.2.335 · Cited by 1
State of the Art Reviews : Male Menopause: Fact or Fiction?
Wald, M., Miner, M. M., & Seftel, A. D. (2008) · American Journal of Lifestyle Medicine · doi:10.1177/1559827607311513 · Cited by 1
Kaplan, S. A. (2006) · British Journal of Urology · doi:10.1111/j.1464-410x.2006.06106.x · Cited by 1
Perleth, M. (2007) · Zeitschrift für ärztliche Fortbildung und Qualität im Gesundheitswesen - German Journal for Quality in Health Care · doi:10.1016/j.zgesun.2007.08.031 · Cited by 1
Approaches to testosterone supplementation in the young adult male
Schwarcz, M., Swerdloff, R. S., & Wang, C. (2007) · Current Sexual Health Reports · doi:10.1007/s11930-007-0022-1 · Cited by 1
Self-citationPodhaisky, H.-P., Mellinger, U., & Moore, C. (2005) · Journal für Kardiologie (Krause & Pachernegg GmbH) · Cited by 1
Exercise, stress and immune system functional responses
Smith, C. (2004) · SUNScholar (Stellenbosch University) · Cited by 1
Kaminetsky, J. C. (2005) · Clinical cornerstone · doi:10.1016/s1098-3597(05)80090-0 · Cited by 1
Cancer as a microevolutionary process
Komarova, N. L., & Wodarz, D. (2007) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780199207466.003.0022 · Cited by 1
Whole-genome analysis of pathogen evolution
Parkhill, J. (2007) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780199207466.003.0015 · Cited by 1
Meier, C., Seibel, M. J., & Handelsman, D. J. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-374602-3.00035-3 · Cited by 1
The interrelationship of sex steroid levels, body composition and bone characteristics in men
Lapauw, B. (2009) · Ghent University Academic Bibliography (Ghent University)
Rabijewski, M., Papierska, L., Kozakowski, J., & Zgliczyński, W. (2012) · Postępy Nauk Medycznych
Androgens and Endocrine Function in Aging Men: Effects on Sexual and General Health
Gooren, L. J. (2008) · Wiley eBooks · doi:10.1002/9781118269978.ch5
Medikamente zur Behandlung sexueller Funktionsstörungen
Müller, M. J., Benkert, O., & Sommer, F. O. (2011) · Springer eBooks · doi:10.1007/978-3-642-19844-1_59
Terapia de reemplazo hormonal con testosterona y cáncer de próstata
Valzacchi, G. R. (2009) · Revista Argentina de Urología
Testosterone Supplementation Effects on Low BMD in Males Ages 19-62: A Six-Month Intervention
Palmer, K. K. (2012) · Aquila Digital Community (University of Southern Mississippi)
Hormonal Evaluation and Treatment
Heaton, J. P. W., & Morales, Á. (2007) · Humana Press eBooks · doi:10.1007/978-1-59745-155-0_6
As, A., Morgunov, L. Y., & Olisaev, R. V. (2007) · Diabetes Mellitus · doi:10.14341/2072-0351-5798
The Effect of Testosterone Therapy on the Mortality Rate in Men Suffering From Diabetes Mellitus
Tran, D. (2015) · CommonKnowledge Research Repository (Pacific University Oregon)
Testosterone Replacement Therapy in Men: Effects on Fertility and Health
Chan, P. T. K. (2013) · Springer eBooks · doi:10.1007/978-1-4614-7187-5_4
Pomerol, J. M. (2008) · Revista Internacional de Andrología · doi:10.1016/s1698-031x(08)76155-7
Impact of androgen deficiency on sexual dysfunction
Gore, J. L., & Rajfer, J. (2007) · Current Sexual Health Reports · doi:10.1007/bf02938328
The role for intramuscular testosterone injection in the gel era
Yassin, A. A. (2007) · Current Sexual Health Reports · doi:10.1007/s11930-007-0014-1
Does individual response to androgen replacement therapy affect bone density?
Liu, P. Y., Wang, C., & Swerdloff, R. S. (2006) · Nature Clinical Practice Endocrinology & Metabolism · doi:10.1038/ncpendmet0094
Self-citationKo, Y., Lew, Y.-M., Jung, S.-W., Joe, S.-H., Lee, C. H., Jung, H.-G., & Lee, M. (2009) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0b013e31819d735b
Therapeutic Potential of Testosterone Gels
Lunenfeld, B., & Oettel, M. (2009) · Aging Health · doi:10.2217/ahe.09.6
Effects of Androgen on the Cardiovascular System in the Aging Male
Kim, J. W., Kim, J. J., & Moon, D. G. (2011) · Korean Journal of Andrology · doi:10.5534/kja.2011.29.1.10
For information on reprint requests of more than 101 and commercial reprints contact
Barbour, L. A., Cobin, R. H., DeGroot, L. J., Glinoer, D., Mandel, S. J., & Edwards, H. A. (2008)
It is time for a large trial of testosterone therapy for older men
Buvat, J. (2006) · The Journal of Men s Health and Gender · doi:10.1016/j.jmhg.2006.05.007
Raising testosterone levels in men with hypogonadism
Carson, M. N. (2006) · Independent Nurse · doi:10.12968/indn.2006.1.6.73938
Testosterone and frailty in elderly men
Emmelot‐Vonk, M. H. (2009) · Utrecht University Repository (Utrecht University)
Saul, S. R., & Jaker, M. A. (2015) · Case Reports in Internal Medicine · doi:10.5430/crim.v2n4p38
40 Sex hormones and related compounds, including hormonal contraceptives
Dukes, M. (2007) · Side effects of drugs annual · doi:10.1016/s0378-6080(06)29040-8
Testosterone and Mood in Aging Men
Seidman, S. N., & Orr, G. (2006) · Aging Health · doi:10.2217/1745509x.2.1.61
Testerone Replacement Therapy for Men with Metabolic Syndrome
Soedjono, J. (2011)
As manifestações da ansiedade, depressao e stress no período climatério masculino
Almeida, R. C. F. (2010) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)
Elliott, J. (2016) · uO Research (University of Ottawa) · doi:10.20381/ruor-5176
Metadata
- Authors
- Wang, C., Cunningham, G., Dobs, A., Iranmanesh, A., Matsumoto, A. M., Snyder, P. J., Weber, T., Berman, N., Hull, L., & Swerdloff, R. S.
- Affiliations
- University of California, Los Angeles (US)
- Baylor College of Medicine (US)
- Johns Hopkins University (US)
- Veterans Health Administration (US)
- University of Washington (US)
- University of Pennsylvania Health System (US)
- Duke Medical Center (US)
- Corresponding author
- Wang, Christina
- ORCID
- Venue
- The Journal of Clinical Endocrinology & Metabolism
- Publisher
- The Endocrine Society
- Published
- 2004-05
- Volume
- 89
- Issue
- 5
- Pages
- 2085-2098
- ISSN
- 0021-972X (ISSN-L)
- 1945-7197
- OpenAlex
- W2001118572
- Semantic Scholar
- 2114ced4c5aa202f6d1a0eee503c76ffef92a68a
- Cited by
- 656
- References
- 48
- Citations by year
- 2026: 8 · 2025: 14 · 2024: 4 · 2023: 14 · 2022: 24 · 2021: 6 · 2020: 15 · 2019: 23 · 2018: 23 · 2017: 36 · 2016: 22 · 2015: 30 · 2014: 36 · 2013: 37 · 2012: 40
- FWCI
- 32.97
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Department of Veterans Affairs
- University of Pennsylvania
- Johns Hopkins University
- Deutsches Krebsforschungszentrum
- National Institutes of Health (RR00425)
- National Center for Research Resources (M01RR000030, M01RR000425)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Keywords
- testosterone replacement therapy, transdermal testosterone, hypogonadism, sexual function, mood, lean body mass, fat mass, bone mineral density, dihydrotestosterone, estradiol, gonadotropin suppression, erythrocytosis, prostate-specific antigen, prostate cancer risk, long-term treatment
- MeSH terms
- Adolescent, Adult, Affect, Aged, Androgens, Body Composition, Dose-Response Relationship, Drug, Drug Administration Schedule, Estradiol, Follicle Stimulating Hormone, Gels, Hematocrit, Hemoglobins, Humans, Hypogonadism, Luteinizing Hormone, Male, Prostatic Hyperplasia, Sexual Behavior, Sex Hormone-Binding Globulin, Testosterone, Ultrasonography, Biomarkers, Bone Density, Bone Remodeling, Prostate-Specific Antigen
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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