The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
The Impact of Dietary Protein on Calcium Absorption and Kinetic Measures of Bone Turnover in Women
Abstract
Although high-protein diets induce hypercalciuria in humans, the source of the additional urinary calcium remains unclear. One hypothesis is that the high endogenous acid load of a high-protein diet is partially buffered by bone, leading to increased skeletal resorption and hypercalciuria. We used dual stable calcium isotopes to quantify the effect of a high-protein diet on calcium kinetics in women. The study consisted of 2 wk of a lead-in, well-balanced diet followed by 10 d of an experimental diet containing either moderate (1.0 g/kg) or high (2.1 g/kg) protein. Thirteen healthy women received both levels of protein in random order. Intestinal calcium absorption increased during the high-protein diet in comparison with the moderate (26.2 +/- 1.9% vs. 18.5 +/- 1.6%, P < 0.0001, mean +/- sem) as did urinary calcium (5.23 +/- 0.37 vs. 3.57 +/- 0.35 mmol/d, P < 0.0001, mean +/- sem). The high-protein diet caused a significant reduction in the fraction of urinary calcium of bone origin and a nonsignificant trend toward a reduction in the rate of bone turnover. There were no protein-induced effects on net bone balance. These data directly demonstrate that, at least in the short term, high-protein diets are not detrimental to bone.
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Cites
Effect of Dietary Protein on Bone Loss in Elderly Men and Women: The Framingham Osteoporosis Study
Hannan, M. T., Tucker, K. L., Dawson-Hughes, B., Cupples, L. A., Felson, D. T., & Kiel, D. P. (2000) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2000.15.12.2504 · Cited by 536
Low Protein Intake: The Impact on Calcium and Bone Homeostasis in Humans
Kerstetter, J. E., O'Brien, K. O., & Insogna, K. L. (2003) · The Journal of Nutrition · doi:10.1093/jn/133.3.855s · Cited by 212
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International Society of Sports Nutrition position stand: protein and exercise
Campbell, B., Kreider, R. B., Ziegenfuss, T., La Bounty, P., Roberts, M., Burke, D., Landis, J., Lopez, H., & Antonio, J. (2007) · Journal of the International Society of Sports Nutrition · doi:10.1186/1550-2783-4-8 · Cited by 716
Dietary protein, weight loss, and weight maintenance
Westerterp-Plantenga, M. S., Nieuwenhuizen, A., Tomé, D., Soenen, S., & Westerterp, K. R. (2009) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-080508-141056 · Cited by 570
Optimizing Bone Health in Children and Adolescents
Golden, N. H., Abrams, S. A., COMMITTEE ON NUTRITION, Daniels, S. R., Abrams, S. A., Corkins, M. R., de Ferranti, S. D., Golden, N. H., Magge, S. N., & Schwarzenberg, S. J. (2014) · PEDIATRICS · doi:10.1542/peds.2014-2173 · Cited by 497
Increasing Dietary Protein Requirements in Elderly People for Optimal Muscle and Bone Health
Gaffney‐Stomberg, E., Insogna, K. L., Rodriguez, N. R., & Kerstetter, J. E. (2009) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2009.02285.x · Cited by 226
Self-citationRizzoli, R., Biver, E., Bonjour, J.-P., Coxam, V., Goltzman, D., Kanis, J. A., Lappe, J., Rejnmark, L., Sahni, S., Weaver, C., et al. (2018) · Osteoporosis International · doi:10.1007/s00198-018-4534-5 · Cited by 164
Protein consumption is an important predictor of lower limb bone mass in elderly women
Devine, A., Dick, I. M., Islam, A. F., Dhaliwal, S. S., & Prince, R. L. (2005) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/81.6.1423 · Cited by 110
Shams-White, M. M., Chung, M., Fu, Z., Insogna, K. L., Karlsen, M. C., LeBoff, M. S., Shapses, S. A., Sackey, J., Shi, J., Wallace, T. C., et al. (2018) · PLOS ONE · doi:10.1371/journal.pone.0192459 · Cited by 100
Self-citationAmino acid supplementation alters bone metabolism during simulated weightlessness
Zwart, S. R., Davis-Street, J. E., Paddon-Jones, D., Ferrando, A. A., Wolfe, R. R., & Smith, S. M. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01406.2004 · Cited by 80
de Souza, R. J., Swain, J. F., Appel, L. J., & Sacks, F. M. (2008) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/88.1.1 · Cited by 72
Benefits of high-protein weight loss diets: enough evidence for practice?
Brehm, B. J., & D'Alessio, D. A. (2008) · Current Opinion in Endocrinology, Diabetes & Obesity · doi:10.1097/med.0b013e328308dc13 · Cited by 65
Brown, P. M., Hutchison, J. D., & Crockett, J. C. (2011) · Calcified Tissue International · doi:10.1007/s00223-011-9537-6 · Cited by 37
Effects of high-protein intake on bone turnover in long-term bed rest in women
Heer, M., Baecker, N., Frings-Meuthen, P., Graf, S., Zwart, S. R., Biolo, G., & Smith, S. M. (2017) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2016-0292 · Cited by 24
Optimizing Bone Health in Older Adults: The Importance of Dietary Protein
Surdykowski, A. K., Kenny, A. M., Insogna, K. L., & Kerstetter, J. E. (2010) · Aging Health · doi:10.2217/ahe.10.16 · Cited by 22
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Metadata
- Authors
- Kerstetter, J. E., O’Brien, K. O., Caseria, D. M., Wall, D. E., & Insogna, K. L.
- Venue
- The Journal of Clinical Endocrinology & Metabolism
- Publisher
- The Endocrine Society
- Published
- 2005-01
- Volume
- 90
- Issue
- 1
- Pages
- 26-31
- ISSN
- 0021-972X (ISSN-L)
- 1945-7197
- OpenAlex
- W2170080359
- Cited by
- 290
- References
- 2
- FWCI
- 14.65
- Type
- journal article
- Language
- en
- Open access
- closed
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