Cited by 287Thyroid Disorders and TreatmentsClinical Laboratory Practices and Quality ControlThyroid Cancer Diagnosis and Treatment

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The Thyrotropin Reference Range Should Remain Unchanged

Surks, Martin I., Goswami, Gayotri, Daniels, Gilbert H.·2005·The Journal of Clinical Endocrinology & Metabolism

DOI 10.1210/jc.2005-0170

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Abstract

CONTEXT: Recent recommendations to decrease the upper limit of the TSH reference range from 4.5 to 2.5 mIU/liter, based on the high proportion of normal people whose serum TSH is less than 2.5 mIU/liter and the observation that those with TSH between 2.5 and 4.5 mIU/liter [upper reference range (URR)] have increased risk of progression to overt hypothyroidism (Whickham, 20-yr data), have not been subjected to critical analysis. STUDY SUBJECTS: The study subjects were from the Reference Group of NHANES III, 14,333 people more than 12 yr old, without known thyroid disease or antithyroid antibodies; 85% had TSH levels below 2.5 mIU/liter, and 2.3% had subclinical hypothyroidism (SCH). An additional 9.7% had URR TSH, representing 20.6 million Americans, who would also be identified as SCH if the upper TSH limit were decreased. Many with URR TSH do not have thyroid disease. INTERVENTION: The time of phlebotomy is important, because the TSH level varies throughout the day, with early morning values greater than later ones, and is accentuated by sleep deprivation, strenuous exercise, or working during the night or evening shifts. Repeated measurements in the same individual vary considerably over months. RESULTS: About half of those with URR TSH probably have thyroid disease, but most with thyroid disease, antithyroid peroxidase antibodies, have TSH below 2.5 mIU/liter. Those with URR TSH with thyroid disease probably have minimal thyroid deficiency, without any reported adverse health consequences or benefit of treatments with levothyroxine. CONCLUSION: Because routine levothyroxine treatment is not recommended for SCH, it is certainly not warranted in individuals with URR TSH. For all patients with URR TSH, it is reasonable to determine serum TSH every 1-2 yr.

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Grundy, S. M., Bilheimer, D. W., Chait, A., Clark, L. T., Denke, M. A., Havel, R. J., Hazzard, W. R., Hulley, S. B., Hunninghake, D. B., Kreisberg, R. A., et al. (1993) · JAMA · doi:10.1001/jama.269.23.3015 · Cited by 27,944
Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
Chobanian, A. V., Bakris, G. L., Black, H. R., Cushman, W. C., Green, L. A., Izzo, J. L., Jones, D. W., Materson, B. J., Oparil, S., Wright, J. T., et al. (2003) · Hypertension · doi:10.1161/01.hyp.0000107251.49515.c2 · Cited by 13,271
Serum TSH, T 4 , and Thyroid Antibodies in the United States Population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)
Hollowell, J. G., Staehling, N. W., Flanders, W. D., Hannon, W. H., Gunter, E. W., Spencer, C. A., & Braverman, L. E. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.87.2.489 · Cited by 4,279
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The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus* (2003) · Diabetes Care · doi:10.2337/diacare.26.11.3160 · Cited by 3,784
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Canaris, G. J., Manowitz, N. R., Mayor, G., & Ridgway, E. C. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.4.526 · Cited by 2,824
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Vanderpump, M. P. J., Tunbrldge, W. M. G., French, J. M., Appleton, D., Bates, D., Clark, F., Evans, J. G., Hasan, D. M., Rodgers, H., Tunbridge, F., et al. (1995) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1995.tb01894.x · Cited by 2,432
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American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the Evaluation and Treatment of Hyperthyroidism and Hypothyroidism
Baskin, H. J., Cobin, R. H., Duick, D. S., Gharib, H., Guttler, R. B., Kaplan, M. M., Segal, R. L., Garber, J. R., Hamilton Jr, C. R., Handelsman, Y., et al. (2002) · Endocrine Practice · doi:10.4158/1934-2403-8.6.457 · Cited by 673
Prediction of all-cause and cardiovascular mortality in elderly people from one low serum thyrotropin result: a 10-year cohort study
Parle, J. V., Maisonneuve, P., Sheppard, M. C., Boyle, P., & Franklyn, J. A. (2001) · The Lancet · doi:10.1016/s0140-6736(01)06067-6 · Cited by 669
American Thyroid Association guidelines for detection of thyroid dysfunction.
Ladenson, P., Singer, P., Ain, K., Bagchi, N., Bigos, S., Levy, E., Smith, S. A., Daniels, G., & Cohen, H. D. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.11.1573 · Cited by 658
Self-citation
Prevalence and follow-up of abnormal thyrotrophin (TSH) concentrations in the elderly in the United Kingdom
Fade, J. V., Franklyn, J. A., Cross, K. W., Jones, S. C., & Sheppard, M. C. (1991) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1991.tb01739.x · Cited by 567
Psychological well‐being in patients on ‘adequate’ doses of l‐thyroxine: results of a large, controlled community‐based questionnaire study
Saravanan, P., Chau, W. ‐., Roberts, N., Vedhara, K., Greenwood, R., & Dayan, C. M. (2002) · Clinical Endocrinology · doi:10.1046/j.1365-2265.2002.01654.x · Cited by 514
Risk for fracture in women with low serum levels of thyroid-stimulating hormone
Bauer, D. C., Ettinger, B., Nevitt, M. C., Stone, K. L., & for the Study of Osteoporotic Fractures Research Group (2001) · Annals of Internal Medicine · doi:10.7326/0003-4819-134-7-200104030-00009 · Cited by 467
Impaired endothelium-dependent vasodilatation in subclinical hypothyroidism: beneficial effect of levothyroxine therapy
Taddei, S., Caraccio, N., Virdis, A., Dardano, A., Versari, D., Ghiadoni, L., Salvetti, A., Ferrannini, E., & Monzani, F. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-030039 · Cited by 431
Effect of Thyroxine Therapy on Serum Lipoproteins in Patients with Mild Thyroid Failure: A Quantitative Review of the Literature
Danese, M. D., Ladenson, P. W., Meinert, C. L., & Powe, N. R. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.85.9.2993 · Cited by 423
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Fish, L. H., Schwartz, H. L., Cavanaugh, J., Steffes, M. W., Bantle, J. P., & Oppenheimer, J. H. (1987) · New England Journal of Medicine · doi:10.1056/nejm198703263161302 · Cited by 353
Subclinical hyperthyroidism as a risk factor for atrial fibrillation
Auer, J., Scheibner, P., Mische, T., Langsteger, W., Eber, O., & Eber, B. (2001) · American Heart Journal · doi:10.1067/mhj.2001.119370 · Cited by 314
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Fractures in Patients with Hyperthyroidism and Hypothyroidism: A Nationwide Follow-Up Study in 16,249 Patients
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American Thyroid Association Guidelines for Use of Laboratory Tests in Thyroid Disorders
Surks, M. I. (1990) · JAMA · doi:10.1001/jama.1990.03440110095035 · Cited by 283
Self-citation
Physiological regulation of circadian and pulsatile thyrotropin secretion in normal man and woman
BRABANT, G., PRANK, K., RANFT, U., SCHUERMEYER, T., WAGNER, T. O. F., HAUSER, H., KUMMER, B., FEISTNER, H., HESCH, R. D., & MÜHLEN, A. V. Z. (1990) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-70-2-403 · Cited by 282
Spontaneous Subclinical Hypothyroidism in Patients Older than 55 Years: An Analysis of Natural Course and Risk Factors for the Development of Overt Thyroid Failure
Díez, J. J., & Iglesias, P. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-032061 · Cited by 281
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Beck-Peccoz, P., Amr, S., Menezes-Ferreira, M. M., Faglia, G., & Weintraub, B. D. (1985) · New England Journal of Medicine · doi:10.1056/nejm198504253121703 · Cited by 261
Elevated C-reactive protein and homocysteine values: cardiovascular risk factors in hypothyroidism? A cross-sectional and a double-blind, placebo-controlled trial
Christ‐Crain, M., Meier, C., Guglielmetti, M., Huber, P., Riesen, W., Staub, J.-J., & Müller-Stich, B. P. (2003) · Atherosclerosis · doi:10.1016/s0021-9150(02)00372-6 · Cited by 243
Biologic Variation is Important for Interpretation of Thyroid Function Tests
Andersen, S., Bruun, N. H., Pedersen, K. M., & Laurberg, P. (2003) · Thyroid · doi:10.1089/105072503770867237 · Cited by 241
Components of biological variation, including seasonality, in blood concentrations of TSH, TT3, FT4, PRL, cortisol and testosterone in healthy volunteers.
Maes, M., Mommen, K., Hendrickx, D., Peeters, D., D’Hondt, P., Ranjan, R., De Meyer, F., & Scharpe, S. (1997) · Clinical Endocrinology · doi:10.1046/j.1365-2265.1997.1881002.x · Cited by 231
A 6-month randomized trial of thyroxine treatment in women with mild subclinical hypothyroidism
Kong, W. M., Sheikh, M. H., Lumb, P. J., Freedman, D. B., Crook, M. A., Doré, C. J., & Finer, N. (2002) · The American Journal of Medicine · doi:10.1016/s0002-9343(02)01022-7 · Cited by 223
FINE ADJUSTMENT OF THYROXINE REPLACEMENT DOSAGE: COMPARISON OF THE THYROTROPHIN RELEASING HORMONE TEST USING A SENSITIVE THYROTROPHIN ASSAY WITH MEASUREMENT OF FREE THYROID HORMONES AND CLINICAL ASSESSMENT
CARR, D., MCLEOD, D. T., PARRY, G., & THORNES, H. M. (1988) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1988.tb01219.x · Cited by 210
The development of ischemic heart disease in relation to autoimmune thyroid disease in a 20-year follow-up study of an English community.
Vanderpump, M. P. J., Tunbridge, W. M. G., French, J. M., Appleton, D. R., Bates, D., Clark, F., Evans, J. G., Rodgers, H., Tunbridge, F. K. E., & Young, E. T. (1996) · PubMed · doi:10.1089/thy.1996.6.155 · Cited by 207
Current status and performance goals for serum thyrotropin (TSH) assays.
Spencer, C., Takeuchi, M., & Kazarosyan, M. (1996) · Clinical Chemistry · doi:10.1093/clinchem/42.1.140 · Cited by 197
Subclinical thyroid disease
Surks, M. I., & Ocampo, E. L. (1996) · The American Journal of Medicine · doi:10.1016/s0002-9343(97)89462-4 · Cited by 192
Self-citation
Subclinical Thyroid Disease
Col, N. F., Surks, M. I., & Daniels, G. H. (2004) · JAMA · doi:10.1001/jama.291.2.239 · Cited by 192
Self-citation
Roles of intensity and duration of nocturnal exercise in causing phase delays of human circadian rhythms.
Buxton, O. M., Frank, S. A., L’Hermite‐Balériaux, M., Leproult, R., Turek, F. W., & Cauter, E. V. (1997) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1997.273.3.e536 · Cited by 167
Germline Mutations of TSH Receptor Gene as Cause of Nonautoimmune Subclinical Hypothyroidism
Alberti, L., Proverbio, M. C., Costagliola, S., Romoli, R., Boldrighini, B., Vigone, M. C., Weber, G., Chiumello, G., Beck‐Peccoz, P., & Persani, L. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.6.8536 · Cited by 153
CIRCADIAN AND 30 MINUTES VARIATIONS IN SERUM TSH AND THYROID HORMONES IN NORMAL SUBJECTS
Weeke, J., & Gundersen, H. J. G. (1978) · European Journal of Endocrinology · doi:10.1530/acta.0.0890659 · Cited by 134
Effect of Normal and Reversed Sleep-Wake Cycles upon Nyctohemeral Rhythmicity of Plasma Thyrotropin: Evidence Suggestive of an Inhibitory Influence in Sleep
PARKER, D. C., Pekary, A. E., & Hershman, J. M. (1976) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-43-2-318 · Cited by 134
Labelling in hypertension: A review of the behavioural and psychological consequences
Macdonald, L. A., Sackett, D. L., Haynes, R. B., & Taylor, D. W. (1984) · Journal of Chronic Diseases · doi:10.1016/0021-9681(84)90070-5 · Cited by 130
Plasma Thyrotropin, Thyroxine, and Triiodothyronine Relationships in Man
AZUKIZAWA, M., Pekary, A. E., Hershman, J. M., & PARKER, D. C. (1976) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-43-3-533 · Cited by 114
Heterophilic Antibodies Remain a Problem for the Immunoassay Laboratory
Ward, G., Mckinnon, L., Badrick, T. C., & Hickman, P. E. (1997) · American Journal of Clinical Pathology · doi:10.1093/ajcp/108.4.417 · Cited by 112
Impact of subclinical hypothyroidism on serum total homocysteine concentrations, the prevalence of coronary heart disease (CHD), and CHD risk factors in the New Mexico Elder Health Survey
Lindeman, R. D., Romero, L. J., Schade, D. S., Wayne, S., Baumgartner, R. N., & Garry, P. J. (2003) · Thyroid · doi:10.1089/105072503322238863 · Cited by 100
Intra- and interindividual biological variation of five analytes used in assessing thyroid function: implications for necessary standards of performance and the interpretation of results.
Browning, M. C., Ford, R. P., Callaghan, S. J., & Fraser, C. G. (1986) · Clinical Chemistry · doi:10.1093/clinchem/32.6.962 · Cited by 94
Long-term variability in serum thyroglobulin and thyroid related hormones in healthy subjects
Feldt-Rasmussen, U., Petersen, P. H., Blaabjerg, O., & Hørder, M. (1980) · Acta Endocrinologica · doi:10.1530/acta.0.0950328 · Cited by 75
Pathophysiology of Pulsatile and Copulsatile Release of Thyroid-Stimulating Hormone, Luteinizing Hormone, Follicle-Stimulating Hormone, and α-Subunit*
SAMUELS, M. H., VELDHUIS, J. D., HENRY, P., & RIDGWAY, E. C. (1990) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-71-2-425 · Cited by 75
Total sleep deprivation and the thyroid axis: effects of sleep and waking activity.
Gary, K. A., Winokur, A., Douglas, S. D., Kapoor, S. C., Zaugg, L., & Dinges, D. F. (1996) · PubMed · Cited by 73
Low Prevalence of Thyrotropin Receptor Mutations in a Large Series of Subjects with Sporadic and Familial Nonautoimmune Subclinical Hypothyroidism
Tonacchera, M., Perri, A., Marco, G. D., Agretti, P., Banco, M., Cosmo, C. D., Grasso, L., Vitti, P., Chiovato, L., & Pinchera, A. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1243 · Cited by 72
Resistance to Thyrotropin (TSH) in Three Families Is not Associated with Mutations in the TSH Receptor or TSH
Xie, J. H., Pannain, S., Pohlenz, J., Weiss, R. E., Moltz, K. C., Morlot, M., Asteria, C., Persani, L., Beck‐Peccoz, P., Parma, J., et al. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.12.4418 · Cited by 70
Incidence and mechanism of spurious increase in serum thyrotropin.
Howanitz, P. J., Howanitz, J. H., Hv, L., & Ennis, K. M. (1982) · Clinical Chemistry · doi:10.1093/clinchem/28.3.427 · Cited by 66
Effects of Subclinical Hypothyroidism and Its Treatment on Serum Lipids
Ineck, B. A., & Ng, T. M. H. (2003) · Annals of Pharmacotherapy · doi:10.1345/aph.1c376 · Cited by 65
Effects of Reducing the Upper Limit of Normal TSH Values
Fatourechi, V. (2003) · JAMA · doi:10.1001/jama.290.24.3195-b · Cited by 61
Interference by anti-immunoglobulin G antibodies in immunoradiometric assays of thyrotropin involving mouse monoclonal antibodies.
ZWEIG, M. H., Csákó, G., Benson, C. C., Weintraub, B. D., & Kahn, B. B. (1987) · Clinical Chemistry · doi:10.1093/clinchem/33.6.840 · Cited by 57
Emerging cardiovascular risk factors in subclinical hypothyroidism: Lack of change after restoration of euthyroidism
Pérez, A., Cubero, J. M., Sucunza, N., Ortega, E., Arcelús, R., Rodrı́guez-Espinosa, J., Ordóñez‐Llanos, J., & Blanco‐Vaca, F. (2004) · Metabolism · doi:10.1016/j.metabol.2004.05.016 · Cited by 52
Serum TSH variability in normal individuals: the influence of time of sample collection.
Scobbo, R. R., VonDohlen, T. W., Hassan, M., & Islam, S. (2004) · PubMed · Cited by 45
Heterophilic Serum Antibodies: A Cause for Falsely Elevated Serum Thyrotropin Levels
BRENNAN, M. D., Klee, G. G., Preissner, C. M., & HAY, I. D. (1987) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(12)65044-7 · Cited by 35
The circadian thyrotropin rhythm is delayed in regular night workers
Weibel, L., BRANDENBERGER, G., Goichot, B., Spiegel, K., Ehrhart, J., & FOLLENIUS, M. (1995) · Neuroscience Letters · doi:10.1016/0304-3940(95)11344-4 · Cited by 27
Thoughts on Prevention of Thyroid Disease in the United States
Cooper, D. S., & Ridgway, E. C. (2002) · Thyroid · doi:10.1089/105072502761016566 · Cited by 24
Artifactual elevation of thyroid-stimulating hormone
Wood, J. M., Gordon, D. L., Rudinger, A. N., & Brooks, M. M. (1991) · The American Journal of Medicine · doi:10.1016/0002-9343(91)80170-q · Cited by 22
Is Subclinical Hypothyroidism Associated With Hyperhomocysteinemia?
Aldasouqi, S. A., Nkansa-Dwamena, D., Bokhari, S., Alzahrani, A. S., Khan, M., Al-Reffi, A., & Merdad, A. (2004) · Endocrine Practice · doi:10.4158/ep.10.5.399 · Cited by 10
What does "functional sensitivity" mean?
Sadler, W. A., Murray, L. M., & Turner, J. G. (1996) · Clinical Chemistry · doi:10.1093/clinchem/42.12.2051 · Cited by 8

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Authors: Surks, M. I., Goswami, G., & Daniels, G. H.
Affiliations: Albert Einstein College of Medicine (US)
Harvard University (US)
Corresponding author: Surks, Martin I.
ORCID: Daniels, Gilbert H.
Venue: The Journal of Clinical Endocrinology & Metabolism
Publisher: The Endocrine Society
Published: 2005-09
Volume: 90
Issue: 9
Pages: 5489-5496
ISSN: 0021-972X (ISSN-L)
1945-7197
DOI: 10.1210/jc.2005-0170
OpenAlex: W2098761773
Cited by: 287
References: 65
Citations by year: 2026: 4 · 2025: 3 · 2024: 3 · 2023: 4 · 2022: 12 · 2021: 7 · 2020: 4 · 2019: 9 · 2018: 15 · 2017: 15 · 2016: 15 · 2015: 14 · 2014: 18 · 2013: 24 · 2012: 16
FWCI: 13.66
Type: journal article
Language: en
Open access: closed
Locations: The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
Health Sciences › Health Professions › Medical Laboratory Technology › Clinical Laboratory Practices and Quality Control
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Cancer Diagnosis and Treatment
Keywords: upper reference limit, subclinical hypothyroidism, levothyroxine therapy, thyroid peroxidase antibodies, thyroid dysfunction, NHANES III, thyroid screening
MeSH terms: Humans, Hypothyroidism, Reference Values, Thyrotropin, Thyroxine

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Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

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The Thyrotropin Reference Range Should Remain Unchanged

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