Epicardial Adipose Tissue and Insulin Resistance in Obese Subjects

Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus

The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus* (2002) · Diabetes Care · doi:10.2337/diacare.25.2007.s5 · Cited by 10,325

Glucose clamp technique: a method for quantifying insulin secretion and resistance.

DeFronzo, R. A., Tobin, J. D., & Andres, R. (1979) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1979.237.3.e214 · Cited by 7,425

Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp

Matsuda, M., & DeFronzo, R. A. (1999) · Diabetes Care · doi:10.2337/diacare.22.9.1462 · Cited by 5,621

Human epicardial adipose tissue is a source of inflammatory mediators

Mazurek, T., Zhang, L., Zalewski, A., Mannion, J. D., Diehl, J. T., Arafat, H., Sarov-Blat, L., O’Brien, S., Keiper, E. A., Johnson, A. G., et al. (2003) · Circulation · doi:10.1161/01.cir.0000099542.57313.c5 · Cited by 1,966

The glycemic index: methodology and clinical implications

Wolever, T., Jenkins, D., Jenkins, A., & Josse, R. (1991) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/54.5.846 · Cited by 1,168

Echocardiographic epicardial adipose tissue is related to anthropometric and clinical parameters of metabolic syndrome: a new indicator of cardiovascular risk

Iacobellis, G., Ribaudo, M. C., Assael, F., Vecci, E., Tiberti, C., Zappaterreno, A., Di Mario, U., & Leonetti, F. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-030698 · Cited by 842

Epicardial fat from echocardiography: A new method for visceral adipose tissue prediction

Iacobellis, G., Assael, F., Ribaudo, M. C., Zappaterreno, A., Alessi, G., Di Mario, U., & Leonetti, F. (2003) · Obesity Research · doi:10.1038/oby.2003.45 · Cited by 779

Relationships of generalized and regional adiposity to insulin sensitivity in men.

Abate, N., Garg, A., Peshock, R. M., Stray-Gundersen, J., & Grundy, S. M. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118083 · Cited by 759

Adiponectin expression in human epicardial adipose tissue in vivo is lower in patients with coronary artery disease

Iacobellis, G., Pistilli, D., Gucciardo, M., Leonetti, F., Miraldi, F., Brancaccio, G., GALLO, P., & Gioia, C. R. T. D. (2005) · Cytokine · doi:10.1016/j.cyto.2004.11.002 · Cited by 445

Relationship between Generalized and Upper Body Obesity to Insulin Resistance in Asian Indian Men

Chandalia, M., Abate, N., Garg, A., Stray‐Gundersen, J., & Grundy, S. M. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.7.5817 · Cited by 402

Effects of bariatric surgery on pericardial ectopic fat depositions and cardiovascular function

van Schinkel, L. V., Sleddering, M. A., Lips, M., Jonker, J., de Roos, A., Lamb, H., Jazet, I., Pijl, H., & Smit, J. W. (2014) · Clinical Endocrinology · doi:10.1111/cen.12402 · Cited by 45

Epicardial adipose tissue and pericoronary fat thickness measured with 64-multidetector computed tomography: potential predictors of the severity of coronary artery disease

Demirçelik, M. B., Yılmaz, Ö. Ç., Gurel, O. M., Selçoki, Y., Atar, I., Bozkurt, A., Akın, K., & Eryonucu, B. (2014) · Clinics · doi:10.6061/clinics/2014(06)04 · Cited by 49

Adiposity of the Heart

Iacobellis, G., & Sharma, A. M. (2006) · Annals of Internal Medicine · doi:10.7326/0003-4819-145-7-200610030-00021 · Cited by 48

Epicardial adipose tissue and coronary artery calcification in psoriasis patients

Torres, T. R., Bettencourt, N., Mendonça, D. M., Vasconcelos, C., Gama, V., da Silva, B. M., & Selores, M. (2014) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.12516 · Cited by 47

Association of Pericardial Fat With Liver Fat and Insulin Sensitivity After Diet‐Induced Weight Loss in Overweight Women

Bosy‐Westphal, A., Kossel, E., Goele, K., Blöcker, T., Lagerpusch, M., Later, W., Heller, M., Glüer, C., & Müller, M. J. (2010) · Obesity · doi:10.1038/oby.2010.49 · Cited by 47

Relationship Between Coronary Artery Disease and Epicardial Adipose Tissue Quantification at Cardiac CT

Bastarrika, G., Broncano, J., Schoepf, U. J., Schwarz, F., Lee, Y. S., Abro, J. A., Costello, P., & Zwerner, P. L. (2010) · Academic Radiology · doi:10.1016/j.acra.2010.01.015 · Cited by 47

The role of epicardial adipose tissue remodelling in heart failure with preserved ejection fraction

Janssen-Telders, C., Eringa, E. C., de Groot, J. R., de Man, F. S., & Handoko, M. L. (2025) · Cardiovascular Research · doi:10.1093/cvr/cvaf056 · Cited by 57

Epicardial fat, abdominal adiposity and insulin resistance in obese pre-pubertal and early pubertal children

Manco, M., Morandi, A., Marigliano, M., Rigotti, F., Manfredi, R. M., & Maffeis, C. (2012) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2012.11.023 · Cited by 46

Physical exercise and epicardial adipose tissue: A systematic review and meta-analysis of randomized controlled trials

Saco‐Ledo, G., Valenzuela, P. L., Castillo‐García, A., Arenas, J., León‐Sanz, M., Ruilope, L. M., & Lucia, A. (2021) · Obesity Reviews · doi:10.1111/obr.13103 · Cited by 47

Epicardial adipose tissue is related to cardiac function in elderly women, but not in men

Kim, S.-A., Kim, M., Shim, W., & Park, S. (2016) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2016.11.001 · Cited by 46

Increased epicardial fat tissue is a marker of subclinical atherosclerosis in patients with psoriasis

Sen, B., Atci, N., Rifaioğlu, E. N., Ekiz, Ö., Kartal, İ., Büyükkaya, E., Kurt, M., Karakaş, M. F., Büyükkaya, Ş., Akçay, A. B., et al. (2013) · British Journal of Dermatology · doi:10.1111/bjd.12569 · Cited by 44

Association of epicardial fat with left ventricular diastolic function in subjects with metabolic syndrome: assessment using 2-dimensional echocardiography

Park, H. E., Choi, S.-Y., & Kim, M. (2014) · BMC Cardiovascular Disorders · doi:10.1186/1471-2261-14-3 · Cited by 43

Increased epicardial adipose tissue in type 1 diabetes is associated with central obesity and metabolic syndrome

Momesso, D. P., Bussade, I., Epifanio, M. A., Schettino, C. D. S., Russo, L. A. T., & Kupfer, R. (2011) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2010.09.037 · Cited by 42

COVID‐19 infection, progression, and vaccination: Focus on obesity and related metabolic disturbances

Westheim, A. J. F., Bitorina, A. V., Theys, J., & Shiri‐Sverdlov, R. (2021) · Obesity Reviews · doi:10.1111/obr.13313 · Cited by 44

Epicardial adipose tissue, hepatic steatosis and obesity

Çıkım, A. S., Topal, E., Harputluoglu, M. M. M., Keskin, L., Zengin, Z., Cikim, K., Оздемир, Р., Aladağ, M. A., & Yoloğlu, S. (2007) · Journal of Endocrinological Investigation · doi:10.1007/bf03346328 · Cited by 41

High released lactate by epicardial fat from coronary artery disease patients is reduced by dapagliflozin treatment

Couselo‐Seijas, M., Agra-Bermejo, R. M., Fernández, Á. L., Martínez‐Comendador, J. M., Sierra, J., Pérez, M. S., Rozados-Luís, A., González‐Juanatey, J. R., & Eirás, S. (2019) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2019.11.016 · Cited by 44

The Relationship of Ectopic Lipid Accumulation to Cardiac and Vascular Function in Obesity and Metabolic Syndrome

Ruberg, F. L., Chen, Z., Hua, N., Bigornia, S., Guo, Z., Hallock, K., Jara, H. J., LaValley, M. P., Phinikaridou, A., Qiao, Y., et al. (2009) · Obesity · doi:10.1038/oby.2009.363 · Cited by 43

Early Impairment of Transmural Principal Strains in the Left Ventricular Wall After Short-Term, High-Fat Feeding of Mice Predisposed to Cardiac Steatosis

Hankiewicz, J. H., Banke, N. H., Farjah, M., & Lewandowski, E. D. (2010) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.110.959098 · Cited by 42

CPAP therapy induces favorable short-term changes in epicardial fat thickness and vascular and metabolic markers in apparently healthy subjects with obstructive sleep apnea-hypopnea syndrome (OSAHS)

Kostopoulos, K. G., Alhanatis, E., Παμπούκας, Κ., Georgiopoulos, G. A., Zourla, A., Panoutsopoulos, A., Kallianos, A., Velentza, L., Zarogoulidis, P., & Trakada, G. (2015) · Sleep And Breathing · doi:10.1007/s11325-015-1236-5 · Cited by 41

Epicardial adipose tissue thickness in type 1 diabetic patients

Yazıcı, D., Özben, B., Yavuz, D. G., Deyneli, O., Aydın, H., Tarçın, Ö., & Akalın, S. (2011) · Endocrine · doi:10.1007/s12020-011-9478-x · Cited by 41

Epicardial Adipose Tissue Contributes to the Development of Non-Calcified Coronary Plaque: A 5-Year Computed Tomography Follow-up Study

Hwang, I., Park, H. E., & Choi, S. (2016) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.36467 · Cited by 39

Epicardial Adipose Tissue in Cardiovascular Disease

Berg, G. A., Miksztowicz, V., Morales, C., & Barchuk, M. (2019) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-11488-6_9 · Cited by 41

Relationship of Epicardial Adipose Tissue Thickness with Early Indicators of Atherosclerosis and Cardiac Functional Changes in Obese Adolescents with Metabolic Syndrome

Bedir, A. M., Mehmet, B., & Cevriye, A. (2013) · Journal of Clinical Research in Pediatric Endocrinology · doi:10.4274/jcrpe.1064 · Cited by 41

Epicardial adipose tissue: friendly companion or hazardous neighbour for adjacent coronary arteries?

Chaowalit, N., & López-Jiménez, F. A. (2008) · European Heart Journal · doi:10.1093/eurheartj/ehm643 · Cited by 41

Epicardial adipose tissue and cardiometabolic risk factors in overweight and obese children and adolescents

Schusterová, I., Leenen, F. H. H., Jurko, A., Sabol, F., & Takacova, J. (2013) · Pediatric Obesity · doi:10.1111/j.2047-6310.2012.00134.x · Cited by 39

Association Between the Presence or Severity of Coronary Artery Disease and Pericardial Fat, Paracardial Fat, Epicardial Fat, Visceral Fat, and Subcutaneous Fat as Assessed by Multi-Detector Row Computed Tomography

Ueda, Y., Shiga, Y., Idemoto, Y., Tashiro, K., Motozato, K., Koyoshi, R., Kuwano, T., Fujimi, K., Ogawa, M., Saku, K., et al. (2018) · International Heart Journal · doi:10.1536/ihj.17-234 · Cited by 39

Plasma adiponectin and insulin sensitivity in overweight and normal-weight middle-aged premenopausal women

Jürimäe, J., Jürimäe, T., Ring‐Dimitriou, S., LeMura, L. M., Arciero, P. J., & von DUVILLARD, S. P. (2009) · Metabolism · doi:10.1016/j.metabol.2008.12.009 · Cited by 39

Pericardial fat is more abundant in patients with coronary atherosclerosis and even in the non-obese patients: evaluation with cardiac CT angiography

Yong, H. S., Kim, E. J., Seo, H. S., Kang, E.-Y., Kim, Y. K., Woo, O. H., & Han, H. S. (2009) · International journal of cardiac imaging · doi:10.1007/s10554-009-9542-2 · Cited by 37

La grasa epicárdica se relaciona con la visceral, el síndrome metabólico y la resistencia a la insulina en mujeres menopáusicas

Muñoz, M. J. F., Acevedo, L. B., Pérez, N. C., Martinez, A. L., Gutiérrez, N. T., Vega-García, S., Cruz, A. R., Martínez, A. D., García, R. S., Treviño, A. Z., et al. (2014) · Revista Española de Cardiología · doi:10.1016/j.recesp.2013.10.013 · Cited by 36

Caloric restriction lowers endocannabinoid tonus and improves cardiac function in type 2 diabetes

van Eyk, H. J., van Schinkel, L. D., Kantae, V., Dronkers, C. E. A., Westenberg, J. J. M., Roos, A., Lamb, H. J., Jukema, J. W., Harms, A. C., Hankemeier, T., et al. (2018) · Nutrition and Diabetes · doi:10.1038/s41387-017-0016-7 · Cited by 36

Precocious Preclinical Cardiovascular Sonographic Markers in Metabolically Healthy and Unhealthy Childhood Obesity

Corica, D., Oreto, L., Pepe, G., Calabrò, M. P., Longobardo, L., Morabito, L. A., Pajno, G. B., Alibrandi, A., Aversa, T., & Wasniewska, M. G. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00056 · Cited by 35

Hypertrophy and Insulin Resistance of Epicardial Adipose Tissue Adipocytes: Association with the Coronary Artery Disease Severity

Naryzhnaya, N. V., Анатольевна, К. О., Кологривова, И. В., Анатольевна, Х. О., Евтушенко, В. В., & Boshchenko, A. A. (2021) · Biomedicines · doi:10.3390/biomedicines9010064 · Cited by 35

Pioglitazone reduces epicardial fat and improves diastolic function in patients with type 2 diabetes

Moody, A. J., Molina‐Wilkins, M., Clarke, G. D., Merovci, A., Solis‐Herrera, C., Cersósimo, E., CHILTON, R. J., Iozzo, P., Gastaldelli, A., Abdul‐Ghani, M. A., et al. (2022) · Diabetes Obesity and Metabolism · doi:10.1111/dom.14885 · Cited by 37

Epicardial Adipose Tissue in Patients with Chronic Obstructive Pulmonary Disease

Zagaceta, J., Zulueta, J. J., Bastarrika, G., Colina, I., Alcaide, A. B., Campo, A., Celli, B. R., & de-Torres, J. P. (2013) · PLoS ONE · doi:10.1371/journal.pone.0065593 · Cited by 32

A relationship between echocardiographic subepicardial adipose tissue and metabolic syndrome

Okyay, K., Balcıoğlu, A. S., Tavıl, Y., Taçoy, G. A., Türkoğlu, S., & Abacı, A. (2008) · International journal of cardiac imaging · doi:10.1007/s10554-008-9295-3 · Cited by 33

Threshold value of subepicardial adipose tissue to detect insulin resistance in obese children

Abacı, A., Taşçılar, M. E., Sarıtaş, T., Yozgat, Y., Yeşilkaya, E., Kilic, A. O., Okutan, V., & Lenk, M. K. (2009) · International Journal of Obesity · doi:10.1038/ijo.2009.1 · Cited by 35

Tejido adiposo epicárdico: ¿más que un simple depósito de grasa?

Lima-Martínez, M. M., de Suárez, C. B., & Iacobellis, G. (2012) · Endocrinología y Nutrición · doi:10.1016/j.endonu.2012.08.001 · Cited by 34

Epicardial adipose tissue: More than a simple fat deposit?

Lima-Martínez, M. M., de Suárez, C. B., & Iacobellis, G. (2013) · Endocrinología y Nutrición (English Edition) · doi:10.1016/j.endoen.2012.08.013 · Cited by 33

Risk Factors and Genetics of Atrial Fibrillation

ANUMONWO, J. M. B., & Kalifa, J. (2014) · Cardiology Clinics · doi:10.1016/j.ccl.2014.07.007 · Cited by 32

Pericardial fat, insulin resistance, and left ventricular structure and function in morbid obesity

Pucci, G., Battista, F., VUONO, S. D., Boni, M., Scavizzi, M., Ricci, M. A., Lupattelli, G., & Schillaci, G. (2013) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2013.09.016 · Cited by 32

Risk Factors and Genetics of Atrial Fibrillation

ANUMONWO, J. M. B., & Kalifa, J. (2016) · Heart Failure Clinics · doi:10.1016/j.hfc.2015.08.013 · Cited by 31

Assessment of Subclinical Atherosclerosis by Carotid Intima–Media Thickness and Epicardial Adipose Tissue Thickness in Prediabetes

Altın, C., Sade, L. E., Gezmiş, E., Özen, N., Duzceker, O., Bozbaş, H., Eroğlu, S., & Müderrisoğlu, H. (2016) · Angiology · doi:10.1177/0003319716643669 · Cited by 31

The influence of pericardial fat upon left ventricular function in obese females: evidence of a site-specific effect

Hua, N., Chen, Z., Phinikaridou, A., Pham, T. A., Qiao, Y., LaValley, M. P., Bigornia, S., Ruth, M. R., Apovian, C. M., Ruberg, F. L., et al. (2014) · Journal of Cardiovascular Magnetic Resonance · doi:10.1186/1532-429x-16-37 · Cited by 30

Obesity, inflammation, and insulin resistance

Martins, L. M., de Oliveira, A. R. S., Cruz, K. J. C., Torres‐Leal, F. L., & Marreiro, D. D. N. (2014) · Brazilian Journal of Pharmaceutical Sciences · doi:10.1590/s1984-82502014000400003 · Cited by 30

Comparison of epicardial adipose tissue (EAT) thickness and anthropometric measurements in metabolic syndrome (MS) cases above and under the age of 65

Karadağ, B., Türkmen, B. Ö., Öztürk, F. Y., Öztekın, E., Şener, N., & Altuntaş, Y. (2010) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2010.06.016 · Cited by 30

Liver Attenuation, Pericardial Adipose Tissue, Obesity, and Insulin Resistance: The Multi‐Ethnic Study of Atherosclerosis (MESA)

McAuley, P. A., Hsu, F., Loman, K. K., Carr, J. J., Budoff, M. J., Szklo, M., Sharrett, A. R., & Ding, J. (2011) · Obesity · doi:10.1038/oby.2011.191 · Cited by 29

Epicardial Adipose Tissue in the General Middle-aged Population and Its Association With Metabolic Syndrome

Goena, Á. C., Barba, J., Guembe, M. J., Dı́ez, J., Berjón, J., Martínez‐Vila, E., Irimia, P., & Toledo, E. (2016) · Revista Española de Cardiología (English Edition) · doi:10.1016/j.rec.2016.08.001 · Cited by 31

Impaired Adipogenesis and Insulin Resistance in Epicardial Fat‐Mesenchymal Cells From Patients With Cardiovascular Disease

Fernández‐Trasancos, Á., Fandiño‐Vaquero, R., Agra, R. M., Fernández, Á. L., Viñuela, J. E., González‐Juanatey, J. R., & Eiras-Penas, S. (2014) · Journal of Cellular Physiology · doi:10.1002/jcp.24619 · Cited by 29

The role of cardiac fat in insulin resistance

Gastaldelli, A., Morales, M. A., Marraccini, P., & Sicari, R. (2012) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0b013e328358be7b · Cited by 28

Increased epicardial adipose tissue thickness is a predictor of new-onset diabetes mellitus in patients with coronary artery disease treated with high-intensity statins

Kang, J., Kim, Y.-C., Park, J. J., Kim, S., Kang, S., Cho, Y. J., Yoon, Y. E., Oh, I., Yoon, C., Suh, J., et al. (2018) · Cardiovascular Diabetology · doi:10.1186/s12933-017-0650-3 · Cited by 28

Assessment of epicardial adipose tissue on virtual non-contrast images derived from photon-counting detector coronary CTA datasets

Risch, F., Schwarz, F., Braun, F. M., Bette, S. J., Becker, J., Scheurig‐Muenkler, C., Kröncke, T. J., & Decker, J. A. (2022) · European Radiology · doi:10.1007/s00330-022-09257-6 · Cited by 28

Race and epicardial fat: the impact of anthropometric measurements, percent body fat and sex.

Salami, S., Tucciarone, M., Bess, R. L., Kolluru, A., Szpunar, S. M., Rosman, H., & Cohen, G. I. (2013) · PubMed · Cited by 28

Pericardial Fat and Atrial Conduction Abnormalities in the Multiethnic Study of Atherosclerosis (MESA)

Babcock, M. J., Soliman, E. Z., Ding, J., Kronmal, R. A., & Goff‐Jr, D. C. (2010) · Obesity · doi:10.1038/oby.2010.121 · Cited by 28

Association Between Epicardial Fat Thickness and Weight Homeostasis Hormones in Patients With Noncachectic Heart Failure

Karayannis, G., Giamouzis, G., Tziolas, N., Georgoulias, P., Skoularigis, J. S., Mikhailidis, D. P., & Triposkiadis, F. K. (2012) · Angiology · doi:10.1177/0003319712447978 · Cited by 27

Differential behaviour of epicardial adipose tissue-secretomes with high and low orosomucoid levels from patients with cardiovascular disease in H9C2 cells

Lage, R., Moscoso, I., Fernández‐Trasancos, Á., Cebro-Márquez, M., Couselo‐Seijas, M., Fandiño‐Vaquero, R., Bravo, S. B., Sierra, J. C., González‐Juanatey, J. R., & Eirás, S. (2015) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2015.08.025 · Cited by 26

Epicardial Fat from Guinea Pig: A Model to Study the Paracrine Network of Interactions between Epicardial Fat and Myocardium?

Swifka, J., Weiß, J., Addicks, K., Eckel, J., & Rosen, P. (2008) · Cardiovascular Drugs and Therapy · doi:10.1007/s10557-008-6085-z · Cited by 26

Thiazolidinedione insulin sensitizers and the heart: a tale of two organs?

Buckingham, R. E., & Hanna, A. (2007) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2006.00700.x · Cited by 26

Clinical physiology of NAFLD: a critical overview of pathogenesis and treatment

Lonardo, A., Caldwell, S. H., & Loria, P. (2010) · Expert Review of Endocrinology & Metabolism · doi:10.1586/eem.10.5 · Cited by 25

Assessment of epicardial adipose tissue and carotid/femoral intima media thickness in insulin resistance

Altın, C., Sade, L. E., Gezmiş, E., Yılmaz, M., Özen, N., & Müderrisoğlu, H. (2016) · Journal of Cardiology · doi:10.1016/j.jjcc.2016.08.006 · Cited by 26

Threshold Values of High-risk Echocardiographic Epicardial Fat Thickness

Iacobellis, G., Willens, H. J., Bárbaro, G., & Sharma, A. M. (2008) · Obesity · doi:10.1038/oby.2008.145 · Cited by 25

Diabesity in Elderly Cardiovascular Disease Patients: Mechanisms and Regulators

García‐Vega, D., González‐Juanatey, J. R., & Eirás, S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23147886 · Cited by 26

Targeting epicardial adipose tissue: A potential therapeutic strategy for heart failure with preserved ejection fraction with type 2 diabetes mellitus

Shi, Y., Dong, G., & Guo, M. (2023) · World Journal of Diabetes · doi:10.4239/wjd.v14.i6.724 · Cited by 28

Glucose and Inflammatory Cells Decrease Adiponectin in Epicardial Adipose Tissue Cells: Paracrine Consequences on Vascular Endothelium

Fernández‐Trasancos, Á., Guerola-Segura, R., Paradela‐Dobarro, B., Álvarez, E., García‐Acuña, J. M., Fernández, Á. L., González‐Juanatey, J. R., & Eirás, S. (2015) · Journal of Cellular Physiology · doi:10.1002/jcp.25189 · Cited by 24

Obesity and the Heart

López-Jiménez, F. A., & Cortés-Bergoderi, M. (2011) · Revista Española de Cardiología (English Edition) · doi:10.1016/j.rec.2010.10.011 · Cited by 24

An association study between epicardial fat thickness and cognitive impairment in the elderly

Mazzoccoli, G., Dagostino, M. P., Vinciguerra, M., Ciccone, F., Paroni, G., Seripa, D., Addante, F., Montella, R. C., Cosmo, S. D., Sera, F., et al. (2014) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00175.2014 · Cited by 24

Tissue-specific activation of insulin signaling as a potential target for obesity-related metabolic disorders

Okuma, H., & Tsuchiya, K. (2024) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2024.108699 · Cited by 23

Transcriptome and Molecular Endocrinology Aspects of Epicardial Adipose Tissue in Cardiovascular Diseases: A Systematic Review and Meta-Analysis of Observational Studies

Maghbooli, Z., & Hossein‐Nezhad, A. (2015) · BioMed Research International · doi:10.1155/2015/926567 · Cited by 22

Effects of metformin on epicardial adipose tissue and atrial electromechanical delay of obese children with insulin resistance

Güneş, H., Güneş, H., Özmen, Ş., Çelik, E., & Temiz, F. (2020) · Cardiology in the Young · doi:10.1017/s1047951120002103 · Cited by 22

Higher pericardial adiposity is associated with prevalent diabetes: The Coronary Artery Risk Development in Young Adults study

Alman, A. C., Jacobs, D. R., Lewis, C. E., Snell‐Bergeon, J. K., Carnethon, M. R., Terry, J. G., Goff, D. C., Ding, J., & Carr, J. J. (2015) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2015.12.011 · Cited by 21

Punto de corte de espesor de tejido adiposo epicárdico para predecir síndrome metabólico en población venezolana

Lima-Martínez, M. M., Paoli, M., Donis, J. H., Odreman, R., Torres, C., & Iacobellis, G. (2013) · Endocrinología y Nutrición · doi:10.1016/j.endonu.2013.03.004 · Cited by 21

Perivascular adipose tissue: epiphenomenon or local risk factor?

Schäfer, K., Drosos, I., & Konstantinides, S. (2017) · International Journal of Obesity · doi:10.1038/ijo.2017.121 · Cited by 21

Statins and Higher Diabetes Mellitus Risk: Incidence, Proposed Mechanisms, and Clinical Implications

Guber, K., Pemmasani, G., Malik, A. H., Aronow, W. S., Yandrapalli, S., & Frishman, W. H. (2020) · Cardiology in Review · doi:10.1097/crd.0000000000000348 · Cited by 23

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Wolf, P. S., Winhofer, Y., Krššák, M., & Krebs, M. (2017) · Endocrine Connections · doi:10.1530/ec-17-0031 · Cited by 23

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Alman, A. C., Smith, S. R., Eckel, R. H., Hokanson, J. E., Burkhardt, B. R., Sudini, P. R., Wu, Y., Schauer, I. E., Pereira, R. I., & Snell‐Bergeon, J. K. (2017) · Obesity · doi:10.1002/oby.21875 · Cited by 22

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Liu, Y., Fu, W., Lu, M., Huai, S., Song, Y., & Wei, Y. (2016) · BioMed Research International · doi:10.1155/2016/1629236 · Cited by 22

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Apfaltrer, P., Schindler, A., Schoepf, U. J., Nance, J. W., Tricarico, F., Ebersberger, U., McQuiston, A. D., Meyer, M., Henzler, T., Schoenberg, S. O., et al. (2013) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2013.10.014 · Cited by 20

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Wolf, P. S., Winhofer, Y., Smajis, S., Janković, D., Anderwald, C. H., Trattnig, S., Luger, A., Krebs, M., & Krššák, M. (2016) · PLoS ONE · doi:10.1371/journal.pone.0151301 · Cited by 20

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Goena, Á. C., Barba, J., Guembe, M. J., Díez, J., Berjón, J., Martínez‐Vila, E., Irimia, P., & Toledo, E. (2017) · Revista Española de Cardiología · doi:10.1016/j.recesp.2016.07.025 · Cited by 21

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Yafei, S., El-sewy, F. Z., Youssef, E. A., Ayman, M., Elshafei, M. N., & Abayazeed, R. M. (2019) · Diabetes and Vascular Disease Research · doi:10.1177/1479164119827602 · Cited by 19

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Silaghi, A. C., Poanta, L. I., Valea, A., Pais, R., & Silaghi, H. (2011) · PubMed · Cited by 19

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Şengül, C., Özveren, O., Duman, D., Eroğlu, E., Oduncu, V., Tanboğa, İ. H., Can, M. M., Akgün, T., & Dindar, İ. (2011) · Blood Pressure · doi:10.3109/08037051.2011.569992 · Cited by 19

Epicardial adipose tissue and idiopathic deep venous thrombosis: An association study

Mazzoccoli, G., Copetti, M., Dagostino, M. P., Grilli, M., Fontana, A., Pellegrini, F., & Greco, A. (2012) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2012.05.033 · Cited by 20

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Gökdeniz, T., Erkol, A., Kalaycıoğlu, E., Aykan, A. Ç., Gül, İ., Boyacı, F., Turan, B., & Özkan, M. (2014) · Echocardiography · doi:10.1111/echo.12635 · Cited by 17

Obesity and Preclinical Changes of Cardiac Geometry and Function

Sung, J. K., & Kim, J. (2010) · Korean Circulation Journal · doi:10.4070/kcj.2010.40.2.55 · Cited by 18

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Alnabelsi, T. S., Alhamshari, Y., Mulki, R., Codolosa, J. N., Koshkelashvili, N., Goykhman, I., Pressman, G. S., & Romero‐Corral, A. (2016) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2016.07.012 · Cited by 18

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Hogea, T., Suciu, B. A., Ivănescu, A. D., Carașcă, C., Chinezu, L., Arbănași, E. M., Russu, E., Kaller, R., Arbănași, E. M., Mureșan, A. V., et al. (2023) · Diagnostics · doi:10.3390/diagnostics13010142 · Cited by 17

Meta-Inflammation and New Anti-Diabetic Drugs: A New Chance to Knock Down Residual Cardiovascular Risk

d’Aiello, A., Bonanni, A., Vinci, R., Pedicino, D., Severino, A., Vita, A. D., Filomia, S., Brecciaroli, M., & Liuzzo, G. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24108643 · Cited by 18

Epicardial fat tissue thickness is increased in patients with lichen planus and is linked to inflammation and dyslipidemia

Ertem, A. G., Erdoğan, M., Köseoğlu, C., Akoğlu, G., Özdemir, E., Koseoglu, G., Sivri, S., Keleş, T., Durmaz, T., Aktaş, A., et al. (2016) · Revista Portuguesa de Cardiologia · doi:10.1016/j.repc.2016.04.010 · Cited by 17

Quantification of Epicardial Adipose Tissue

Saremi, F., Mekhail, S., Sefidbakht, S., Thonar, B., Malik, S., & Sarlaty, T. (2011) · Academic Radiology · doi:10.1016/j.acra.2011.03.011 · Cited by 17

Cut-off point of epicardial adipose tissue thickness for predicting metabolic syndrome in Venezuelan population

Lima-Martínez, M. M., Paoli, M., Donis, J. H., Odreman, R., Torres, C., & Iacobellis, G. (2013) · Endocrinología y Nutrición (English Edition) · doi:10.1016/j.endoen.2013.12.007 · Cited by 18

Interplay between epicardial adipose tissue, metabolic and cardiovascular diseases

Bornachea, O., Vea, À., & Llorente‐Cortés, V. (2018) · Clínica e Investigación en Arteriosclerosis · doi:10.1016/j.arteri.2018.03.003 · Cited by 18

Is there an increased cardiovascular risk in patients with prolactinoma? A challenging question

Yazıcı, D., Sünbül, M., Yasar, M., Deyneli, O., & Yavuz, D. G. (2021) · Journal of Clinical Ultrasound · doi:10.1002/jcu.23030 · Cited by 16

Epicardial Adipose Tissue Thickness and Carotid Intima-Media Thickness in Hemodialysis Patients.

Aydın, E., Altın, C., Sakallıoğlu, O., Yılmaz, M., Gezmiş, E., Sade, L. E., & Müderrisoğlu, H. (2017) · Europe PMC (PubMed Central) · doi:10.6515/acs20161023a · Cited by 15

Depot-specific adipose tissue modulation by SGLT2 inhibitors and GLP1 agonists mediates their cardioprotective effects in metabolic disease

Bakkar, N. Z., AlZaim, I., & EL‐Yazbi, A. F. (2022) · Clinical Science · doi:10.1042/cs20220404 · Cited by 19

Correlation between reduction of superior interventricular groove epicardial fat thickness and improvement of insulin resistance after weight loss in obese men

Liang, K., Tsai, I., Lee, W., Lin, S., Lee, W.-L., Lee, I., Fu, C., Wang, J., & Sheu, W. H. (2014) · Diabetology & Metabolic Syndrome · doi:10.1186/1758-5996-6-115 · Cited by 15

Determinants of echocardiographic epicardial adipose tissue in a general middle-aged population - The Cardiovascular Risk in Young Finns Study

Gustafsson, B., Rovio, S., Ruohonen, S., Hutri‐Kähönen, N., Kähönen, M. A. P., Viikari, J. S. A., Pahkala, K., & Raitakari, O. T. (2024) · Scientific Reports · doi:10.1038/s41598-024-61727-7 · Cited by 14

Epicardial fat thickness can predict severity and multivessel distribution in Egyptian patients with atherosclerotic coronary artery stenosis

Kamal, D., Elmoteleb, A. M. A., Samir, R., & Saeed, M. (2018) · The Egyptian Heart Journal · doi:10.1016/j.ehj.2018.04.002 · Cited by 14

Epicardial Fat Tissue Predicts Increased Long-Term Major Adverse Cardiac Event in Patients With Moderate Cardiovascular Risk

Ulucan, Ş., Kaya, Z., Efe, D., Keser, A., Katlandur, H., Aygün, F., Ülgen, M. S., Avcı, A., Çalapkorur, B., & Kaya, M. G. (2014) · Angiology · doi:10.1177/0003319714548211 · Cited by 14

Grasa epicárdica: una nueva herramienta para la evaluación del riesgo cardiometabólico

Lima-Martínez, M. M., & Iacobellis, G. (2011) · Hipertensión y Riesgo Vascular · doi:10.1016/j.hipert.2010.12.003 · Cited by 14

The Relationship between Epicardial Adipose Tissue and Insulin Resistance in Overweight and Obesity Adults

Yong-yuan, X. (2008) · Prevention and Treatment of Cardio-Cerebral-Vascular Disease

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Tan-Ramos, K. C., Sy, R. A., & Choa, V. (2014) · Journal of the ASEAN Federation of Endocrine Societies · doi:10.15605/jafes.029.02.05 · Cited by 1

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Rego, J. O. C., Mesa, A. D. B., Sarmientos, J. C. G., Díaz, I. G., Mustelier, J. V., & Rojas, N. D. A. (2010) · DOAJ (DOAJ: Directory of Open Access Journals)

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Gupta, R., Yadav, K., & Priya, N. (2023) · INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH · doi:10.36106/ijsr/9104329 · Cited by 1

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Muñoz, M. J. F., Acevedo, L. B., Pérez, N. C., Martinez, A. L., Gutiérrez, N. T., Vega-García, S., Cruz, A. R., Martínez, A. D., García, R. S., Treviño, A. Z., et al. (2014) · Revista Española de Cardiología (English Edition) · doi:10.1016/j.rec.2013.10.011 · Cited by 56