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Cited by 256

The DOI matches its Crossref record; 146 of the 146 references it cites were found in a registry or an index.

Endocrine Aspects of Obstructive Sleep Apnea

Attal, Pierre, Chanson, Philippe·2010·The Journal of Clinical Endocrinology & Metabolism

Abstract

Context: Some endocrine and metabolic disorders are associated with a high frequency of obstructive sleep apnea (OSA), and treatment of the underlying endocrine disorder can improve and occasionally cure OSA. On the other hand, epidemiological and interventional studies suggest that OSA increases the cardiovascular risk, and a link between OSA and glucose metabolism has been suggested, via reduced sleep duration and/or quality. Evidence Acquisition: We reviewed the medical literature for key articles through June 2009. Evidence Synthesis: Some endocrine and metabolic conditions (obesity, acromegaly, hypothyroidism, polycystic ovary disease, etc.) can be associated with OSA. The pathophysiological mechanisms of OSA in these cases are reviewed. In rare instances, OSA may be improved or even cured by treatment of underlying endocrine disorders: this is the case of hypothyroidism and acromegaly, situations in which OSA is mainly related to upper airways narrowing due to reversible thickening of the pharyngeal walls. However, when irreversible skeletal defects and/or obesity are present, OSA may persist despite treatment of endocrine disorders and may thus require complementary therapy. This is also frequently the case in patients with obesity, even after substantial weight reduction. Conclusions: Given the potential neurocognitive consequences and increased cardiovascular risk associated with OSA, specific therapy such as continuous positive airway pressure is recommended if OSA persists despite effective treatment of its potential endocrine and metabolic causes. “Apropos of sleep, that sinister adventure of all our nights, we might say that men go to bed daily with an audacity that would be incomprehensible if we did not know that it is the result of ignorance of the danger.” Charles Baudelaire, in “Fusées, IX”

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Metadata

Authors
Attal, P., & Chanson, P.
Venue
The Journal of Clinical Endocrinology & Metabolism
Published
2010-02-01
Volume
95
Issue
2
Pages
483-495
ISSN
  • 0021-972X (ISSN-L)
  • 1945-7197
OpenAlex
W2104719134
Cited by
256
References
146
FWCI
11.79
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Endocrine Aspects of Obstructive Sleep Apnea. https://app.cochat.ai/papers/10.1210/jc.2009-1912
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Attal, P., & Chanson, P. (2010). Endocrine Aspects of Obstructive Sleep Apnea. The Journal of Clinical Endocrinology & Metabolism. https://doi.org/10.1210/jc.2009-1912

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