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Cited by 193

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Disappearance Rates of Endogenous Follicle-Stimulating Hormone in Serum Following Surgical Hypophysectomy in Man

YEN, S. S. C., LLERENA, L. A., PEARSON, O. H., LITTELL, A. S.·1970·The Journal of Clinical Endocrinology & Metabolism
DOI 10.1210/jcem-30-3-325
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Abstract

The disappearance rates of endogenous FSH in serum following complete hypophysectomy were determined in 5 patients. Simultaneous determinations of serum FSH and LH were made in one patient. The hormone concentrations were measured by specific radioimmunoassays. Endogenous FSH disappears from circulation at a much slower rate than endogenous LH (approximately 10-fold). The disappearance rates for FSH, like that of LH, could be resolved into at least 2 exponential components. The initial fast component has a mean t½ of 3.9 hr, which was followed by a second slow component with a mean t½ of 70.4 hr.

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Metadata

Authors
YEN, S. S. C., LLERENA, L. A., PEARSON, O. H., & LITTELL, A. S.
Venue
The Journal of Clinical Endocrinology & Metabolism
Publisher
The Endocrine Society
Published
1970-03
Volume
30
Issue
3
Pages
325-329
ISSN
  • 0021-972X (ISSN-L)
  • 1945-7197
DOI
10.1210/jcem-30-3-325
OpenAlex
W2116374770
Cited by
193
References
0
FWCI
8.83
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Disappearance Rates of Endogenous Follicle-Stimulating Hormone in Serum Following Surgical Hypophysectomy in Man. https://app.cochat.ai/papers/10.1210/jcem-30-3-325
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YEN, S. S. C., LLERENA, L. A., PEARSON, O. H., & LITTELL, A. S. (1970). Disappearance Rates of Endogenous Follicle-Stimulating Hormone in Serum Following Surgical Hypophysectomy in Man. The Journal of Clinical Endocrinology & Metabolism. https://doi.org/10.1210/jcem-30-3-325

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.