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Cited by 505

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Relationships Between Fasting Plasma Glucose Levels and Insulin Secretion During Intravenous Glucose Tolerance Tests

BRUNZELL, JOHN D., ROBERTSON, R. PAUL, LERNER, ROGER L., HAZZARD, WILLIAM R., ENSINCK, JOHN W., BIERMAN, EDWIN L., PORTE, DANIEL·1976·The Journal of Clinical Endocrinology & Metabolism

Abstract

Insulin secretion and glucose disappearance rate were measured in 66 subjects with a wide range of fasting plasma glucose levels. The acute insulin response was present in subjects with fasting glucose levels below 115 mg/dl but was absent above this level. The glucose disappearance rate related to the relative acute insulin response in subjects with fasting glucose below 115 mg/dl and to total insulin response when fasting glucose levels were above 115 mg/dl. A calculated glucose disappearance rate of 1.06 per cent per minute was found when the acute isulin response was zero. All subjects with fasting glucose levels greater than 115 mg/dl had glucose disappearance rates greater than 1.06. These studies support 1) epidemiological data indicating 115 mg/dl as an upper limit of normal for fasting plasma glucose levels and 1.0 per cent per minute as a lower limit of normal for the glucose disappearance rate, and 2) evidence for an important role for the acute insulin response in the determination of glucose disappearance rates during intravenous glucose tolerance tests.

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Crossref · 10.1210/jcem-42-2-222

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Metadata

Authors
BRUNZELL, J. D., ROBERTSON, R. P., LERNER, R. L., HAZZARD, W. R., ENSINCK, J. W., BIERMAN, E. L., & PORTE, D.
Venue
The Journal of Clinical Endocrinology & Metabolism
Published
1976-02
Volume
42
Issue
2
Pages
222-229
ISSN
  • 0021-972X (ISSN-L)
  • 1945-7197
OpenAlex
W2160812382
Cited by
505
References
7
FWCI
12.18
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Relationships Between Fasting Plasma Glucose Levels and Insulin Secretion During Intravenous Glucose Tolerance Tests. https://app.cochat.ai/papers/10.1210/jcem-42-2-222
The paper
BRUNZELL, J. D., ROBERTSON, R. P., LERNER, R. L., HAZZARD, W. R., ENSINCK, J. W., BIERMAN, E. L., & PORTE, D. (1976). Relationships Between Fasting Plasma Glucose Levels and Insulin Secretion During Intravenous Glucose Tolerance Tests. The Journal of Clinical Endocrinology & Metabolism. https://doi.org/10.1210/jcem-42-2-222

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.