Cited by 227Adrenal and Paraganglionic TumorsSexual Differentiation and DisordersAdrenal Hormones and Disorders

Adrenal incidentaloma and patients with homozygous or heterozygous congenital adrenal hyperplasia.

Jaresch, S, Kornely, E, Kley, H K, Schlaghecke, R·1992·The Journal of Clinical Endocrinology & Metabolism

Abstract

Adrenal tumors are being detected more frequently in consequence of the wider application of increasingly sensitive radiological investigation techniques. According to the working hypothesis that more silent adenomas could develop from hyperplastic tissue areas under increased stimulation of the adrenal cortex, heterozygous and homozygous patients with congenital adrenal hyperplasia (CAH) were studied. A high incidence of adrenal masses, nearly 82% in homozygous and 45% in heterozygous patients, was found. There was no correlation between tumor size and serum 17-hydroxyprogesterone concentrations. These tumors are, therefore, probably silent adenomas. On the basis of these results, CAH should always be ruled out in the case of incidentally detected adrenal masses. Since CAH is a relatively frequent disease, and the adrenal carcinoma belongs to the rarest malignant tumors, a malignant transformation of these tumors seems to be unlikely.

Integrity signals

Registry

Crossref · 10.1210/jcem.74.3.1311000

Cites

1 of 1 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Jaresch, S., Kornely, E., Kley, H. K., & Schlaghecke, R.
Affiliations
Heinrich Heine University Düsseldorf (DE)
Venue
The Journal of Clinical Endocrinology & Metabolism
Published
1992-03
Volume
74
Issue
3
Pages
685-689
ISSN
  • 0021-972X (ISSN-L)
  • 1945-7197
OpenAlex
W2037425536
Cited by
227
References
1
Citations by year
2025: 2 · 2024: 6 · 2023: 4 · 2022: 3 · 2021: 9 · 2020: 4 · 2019: 6 · 2018: 6 · 2017: 12 · 2016: 5 · 2015: 8 · 2014: 5 · 2013: 6 · 2012: 6
FWCI
8.33
Type
journal article
Language
en
Open access
closed
Locations
  • The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Surgery › Adrenal and Paraganglionic Tumors
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Sexual Differentiation and Disorders
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
Keywords
adrenal incidentaloma, congenital adrenal hyperplasia, adrenal mass, 17-hydroxyprogesterone, adrenal adenoma, adrenocortical carcinoma, tumor size, adrenal hyperplasia
MeSH terms
Adrenal Gland Neoplasms, Adrenal Hyperplasia, Congenital, Adrenocorticotropic Hormone, Adult, Cortodoxone, Dehydroepiandrosterone, Female, Heterozygote, Homozygote, Humans, Hydroxyprogesterones, Male, Tomography, X-Ray Computed, 17-alpha-Hydroxyprogesterone

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review