Sex hormone-binding globulin: a marker for hyperinsulinemia and/or insulin resistance?

Insulin Resistance and the Polycystic Ovary Syndrome: Mechanism and Implications for Pathogenesis

Dunaif, A. E. (1997) · Endocrine Reviews · doi:10.1210/edrv.18.6.0318 · Cited by 2,776

Insulin Resistance and the Polycystic Ovary Syndrome Revisited: An Update on Mechanisms and Implications

Diamanti-Kandarakis, E., & Dunaif, A. (2012) · Endocrine Reviews · doi:10.1210/er.2011-1034 · Cited by 1,947

Polycystic ovary syndrome

Lawrence, J., Douglas, P., & Gandy, J. (2016) · doi:10.1002/9781119163411.ch73 · Cited by 1,014

The Insulin-Related Ovarian Regulatory System in Health and Disease

Poretsky, L., Cataldo, N. A., Rosenwaks, Z., & Giudice, L. C. (1999) · Endocrine Reviews · doi:10.1210/edrv.20.4.0374 · Cited by 852

Polycystic ovary syndrome

Franks, S. (1997) · Archives of Disease in Childhood · doi:10.1136/adc.77.1.89 · Cited by 802

Estrogen: A master regulator of bioenergetic systems in the brain and body

Rettberg, J. R., Yao, J., & Brinton, R. D. (2014) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2013.08.001 · Cited by 534

The insulin-sensitizing agent troglitazone improves metabolic and reproductive abnormalities in the polycystic ovary syndrome

Dunaif, A. E., Scott, D., Finegood, D. T., Quintana, B., & Whitcomb, R. W. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.81.9.8784087 · Cited by 561

Premature Adrenarche--Normal Variant or Forerunner of Adult Disease?

Ibáñez, L., DiMartino-Nardi, J., Potau, N., & Saenger, P. H. (2000) · Endocrine Reviews · doi:10.1210/edrv.21.6.0416 · Cited by 414

Polycystic Ovary Syndrome Is Associated with Obstructive Sleep Apnea and Daytime Sleepiness: Role of Insulin Resistance1

Vgontzas, A. N., Legro, R. S., Bixler, E. O., Grayev, A., Kales, A., & Chrousos, G. P. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.2.7185 · Cited by 371

Androgens, insulin resistance and vascular disease in men

Kapoor, D., Malkin, C. J., Channer, K. S., & Jones, T. H. (2005) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2005.02299.x · Cited by 317

Clinical manifestations and insulin resistance (IR) in polycystic ovary syndrome (PCOS) among South Asians and Caucasians: is there a difference?

Wijeyaratne, C. N., Balen, A. H., Barth, J. H., & Belchetz, P. E. (2002) · Clinical Endocrinology · doi:10.1046/j.1365-2265.2002.01603.x · Cited by 315

Molecular mechanisms of insulin resistance in polycystic ovary syndrome

Diamanti-Kandarakis, E., & Papavassiliou, A. G. (2006) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2006.05.006 · Cited by 301

The pathophysiology of polycystic ovary syndrome

Tsilchorozidou, T., Overton, C. E., & Conway, G. S. (2003) · Clinical Endocrinology · doi:10.1046/j.1365-2265.2003.01842.x · Cited by 295

Generalized lipodystrophy, congenital and acquired (lipoatrophy)

Seip, M., & Trygstad, O. (1996) · Acta Paediatrica · doi:10.1111/j.1651-2227.1996.tb14262.x · Cited by 293

Breast Cancer and Obesity: An Update

Stephenson, G. D., & Rose, D. P. (2003) · Nutrition and Cancer · doi:10.1207/s15327914nc4501_1 · Cited by 258

Impact of Five Nights of Sleep Restriction on Glucose Metabolism, Leptin and Testosterone in Young Adult Men

Reynolds, A. C., Dorrian, J., Liu, P. Y., Van Dongen, H. P. A., Wittert, G. A., Harmer, L. J., & Banks, S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0041218 · Cited by 231

Decreased testosterone and dehydroepiandrosterone sulfate concentrations are associated with increased insulin and glucose concentrations in nondiabetic men.

Haffner, S. M., Valdez, R. A., Mykkänen, L., Stern, M. P., & Katz, M. S. (1994) · Metabolism · doi:10.1016/0026-0495(94)90202-x · Cited by 226

Hyperinsulinemia and Decreased Insulin-Like Growth Factor-Binding Protein-1 Are Common Features in Prepubertal and Pubertal Girls with a History of Premature Pubarche1

Ibáñez, L., Potau, N., Zampolli, M., RiquÉ, S., Saenger, P., & Carrascosa, A. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.7.4084 · Cited by 199

Hyperinsulinemia and bone mineral density in an elderly population: The Rotterdam study

Stolk, R. P., van Daele, P. L. A., Pols, H. A. P., Burger, H., Hofman, A., Birkenhäger, J. C., Lamberts, S. W. J., & Grobbee, D. E. (1996) · Bone · doi:10.1016/8756-3282(96)00079-8 · Cited by 194

Sex hormone-binding globulin and type 2 diabetes mellitus

Le, T. N., Nestler, J. E., Strauss, J. F., & Wickham, E. P. (2012) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2011.09.005 · Cited by 191

Hormonal Profile of Women with Self-Reported Symptoms of Oligomenorrhea and/or Hirsutism: Northern Finland Birth Cohort 1966 Study

Taponen, S., Martikainen, H. K., Järvelin, M., Laitinen, J. H., Pouta, A. M., Hartikainen, A., Sovio, U., McCarthy, M. I., Franks, S., & Ruokonen, A. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-020982 · Cited by 190

The relationships between AMH, androgens, insulin resistance and basal ovarian follicular status in non-obese subfertile women with and without polycystic ovary syndrome

Nardo, L. G., Yates, A. P., Roberts, S. A., Pemberton, P. W., & Laing, I. (2009) · Human Reproduction · doi:10.1093/humrep/dep225 · Cited by 188

Early Puberty-Menarche After Precocious Pubarche: Relation to Prenatal Growth

Ibáñez, L., Jiménez, R., & de Zegher, F. (2006) · PEDIATRICS · doi:10.1542/peds.2005-0664 · Cited by 183

INSULIN ACTION IN THE POLYCYSTIC OVARY SYNDROME

Dunaif, A. E. (1999) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(05)70073-6 · Cited by 180

Association of Endogenous Sex Hormones and Insulin Resistance among Postmenopausal Women: Results from the Postmenopausal Estrogen/Progestin Intervention Trial

Kalish, G., Barrett-Connor, E. L., Laughlin, G. A., & Gulanski, B. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021375 · Cited by 155

Visceral fat accumulation in relation to sex hormones in obese men and women undergoing weight loss therapy

Leenen, R. C. A., Kooy, K. V. D., Seidell, J. C., Deurenberg, P., & Koppeschaar, H. P. F. (1994) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.78.6.8200956 · Cited by 155

Reconciling the Definitions of Polycystic Ovary Syndrome: The Ovarian Follicle Number and Serum Anti-Müllerian Hormone Concentrations Aggregate with the Markers of Hyperandrogenism

Dewailly, D., Pigny, P., Soudan, B., Catteau-Jonard, S., Decanter, C., Poncelet, É., & Duhamel, A. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-0334 · Cited by 155

Portal insulin concentrations rather than insulin sensitivity regulate serum sex hormone-binding globulin and insulin-like growth factor binding protein 1 in vivo

Yki‐Järvinen, H., Mäkimattila, S., Utriainen, T., & Rutanen, E. ‐. (1995) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.80.11.7593430 · Cited by 150

Is there a menopausal metabolic syndrome?

Spencer, C. P., Godsland, I. F., & Stevenson, J. C. (1997) · Gynecological Endocrinology · doi:10.3109/09513599709152559 · Cited by 144

Polycystic Ovary Syndrome in Adolescence

Buggs, C., & Rosenfield, R. L. (2005) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2005.04.005 · Cited by 147

Sex Hormone-Binding Globulin and Insulin-Like Growth Factor-Binding Protein-1 as Indicators of Metabolic Syndrome, Cardiovascular Risk, and Mortality in Elderly Men

Kalme, T., Seppälä, M. T., Qiao, Q., Koistinen, R. A., Nissinen, A. M., Harrela, M., Loukovaara, M. J., Leinonen, P. J., & Tuomilehto, J. O. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0762 · Cited by 141

17 -Hydroxyprogesterone Responses to Leuprolide and Serum Androgens in Obese Women with and without Polycystic Ovary Syndrome after Dietary Weight Loss

Jakubowicz, D. J., & Nestler, J. E. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.2.3753 · Cited by 138

Determinants of sex hormone—binding globulin blood concentrations in premenopausal and postmenopausal women with different estrogen status

Pasquali, R., Vicennati, V., Bertazzo, D., Casimirri, F., Pascal, G., Tortelli, O., & Labate, A. M. M. (1997) · Metabolism · doi:10.1016/s0026-0495(97)90159-1 · Cited by 130

Influence ofSHBGGene Pentanucleotide TAAAA Repeat and D327N Polymorphism on Serum Sex Hormone-Binding Globulin Concentration in Hirsute Women

Cousin, P., Michel‐Calemard, L., Lejeune, H., Raverot, G., Yessaad, N., Emptoz-Bonneton, A., Morel, Y., & PUGEAT, M. M. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021553 · Cited by 123

Body fat distribution has weight-independent effects on clinical, hormonal, and metabolic features of women with polycystic ovary syndrome

Pasquali, R., Casimirri, F., Venturoli, S., Antonio, M., Morselli, L., Reho, S., Pezzoli, A., & Paradisi, R. (1994) · Metabolism · doi:10.1016/0026-0495(94)90118-x · Cited by 119

Interrelations between sex hormone-binding globulin (SHBG), plasma lipoproteins and cardiovascular risk

Pugeat, M., Moulin, P., Cousin, P., Fimbel, S., Nicolas, M. H., Crave, J. C., & Lejeune, H. (1995) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(95)00102-6 · Cited by 118

The pubertal timing controversy in the USA, and a review of possible causative factors for the advance in timing of onset of puberty

Slyper, A. H. (2006) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2006.02539.x · Cited by 113

Direct Thiazolidinedione Action in the Human Ovary: Insulin-Independent and Insulin-Sensitizing Effects on Steroidogenesis and Insulin-Like Growth Factor Binding Protein-1 Production

Seto‐Young, D., Paliou, M., Schlosser, J., Avtanski, D. B., Park, A., Patel, P., Holcomb, K., Chang, P., & Poretsky, L. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-0469 · Cited by 107

Relationships between endogenous steroid hormone, sex hormone-binding globulin and lipoprotein levels in men: contribution of visceral obesity, insulin levels and other metabolic variables

Tchernof, A., Labrie, F., Bélanger, A., Prud'homme, D., Bouchard, C., Tremblay, A., Nadeau, A., & Després, J.-P. (1997) · Atherosclerosis · doi:10.1016/s0021-9150(97)00125-1 · Cited by 107

Clinical spectrum of premature pubarche: Links to metabolic syndrome and ovarian hyperandrogenism

Ibáñez, L., Díaz, R., López-Bermejo, A., & Marcos, M. V. (2009) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-008-9096-y · Cited by 106

Incidence of elevated LH/FSH ratio in polycystic ovary syndrome women with normo- and hyperinsulinemia.

Banaszewska, B., Spaczyński, R., Pelesz, M., & Pawelczyk, L. A. (2003) · PubMed · Cited by 103

The Role of Obesity in the Development of Polycystic Ovary Syndrome

Motta, A. B. (2012) · Current Pharmaceutical Design · doi:10.2174/13816128112092482 · Cited by 104

Low sex hormone-binding globulin is associated with the metabolic syndrome in postmenopausal women

Weinberg, M. E., Manson, J. E., Buring, J. E., Cook, N. R., Seely, E. W., Ridker, P. M., & Rexrode, K. M. (2006) · Metabolism · doi:10.1016/j.metabol.2006.06.017 · Cited by 101

Endogenous sex hormones: Impact on lipids, lipoproteins, and insulin

Haffner, S. M., & Valdez, R. A. (1995) · The American Journal of Medicine · doi:10.1016/s0002-9343(99)80058-8 · Cited by 101

Decreased bone mineral density at the distal radius, but not at the lumbar spine or the femoral neck, in Japanese type 2 diabetic patients

Majima, T., Komatsu, Y., Yamada, T., Koike, Y., Shigemoto, M., Takagi, C., Hatanaka, I., & Nakao, K. (2004) · Osteoporosis International · doi:10.1007/s00198-004-1786-z · Cited by 99

Prospective study on the role of glucose metabolism in breast cancer occurrence

Sieri, S., Muti, P. C., Agnoli, C., Berrino, F., Pala, V. M., Grioni, S., Abagnato, C. A., Blandino, G., Contiero, P., Schünemann, H. J., et al. (2011) · International Journal of Cancer · doi:10.1002/ijc.26071 · Cited by 99

Hirsutism, Normal Androgens and Diagnosis of PCOS

Spritzer, P. M., Marchesan, L. B., dos Santos, B. R., & Fighera, T. M. (2022) · Diagnostics · doi:10.3390/diagnostics12081922 · Cited by 92

Premature pubarche, ovarian hyperandrogenism, hyperinsulinism and the polycystic ovary syndrome: From a complex constellation to a simple sequence of prenatal onset

Ibáñez, L., de Zegher, F., & Potau, N. (1998) · Journal of Endocrinological Investigation · doi:10.1007/bf03350781 · Cited by 88

Sex hormone-binding globulin levels and cardiovascular risk factors in morbidly obese subjects before and after weight reduction induced by diet or malabsorptive surgery

Mingrone, G., Greco, A., Giancaterini, A., Scarfone, A., Castagneto, M., & Pugeat, M. (2002) · Atherosclerosis · doi:10.1016/s0021-9150(01)00667-0 · Cited by 96

The Roles of Insulin Sensitivity, Insulin-Like Growth Factor I (IGF-I), and IGF-Binding Protein-1 and -3 in the Hyperandrogenism of African-American and Caribbean Hispanic Girls with Premature Adrenarche1

Vuguin, P. M., Linder, B. L., Rosenfeld, R. G., Saenger, P. H., & DiMartino-Nardi, J. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.6.5722 · Cited by 89

Body Composition Is Improved During 12 Months' Treatment With Metformin Alone or Combined With Oral Contraceptives Compared With Treatment With Oral Contraceptives in Polycystic Ovary Syndrome

Glintborg, D., Altinok, M. L., Mumm, H., Hermann, A. P., Ravn, P., & Andersen, M. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2014-1135 · Cited by 88

Testicular dysfunction in human immunodeficiency virus—infected men

Poretsky, L., Can, S., & Zumoff, B. (1995) · Metabolism · doi:10.1016/0026-0495(95)90250-3 · Cited by 86

Serum Dioxin, Insulin, Fasting Glucose, and Sex Hormone-Binding Globulin in Veterans of Operation Ranch Hand

Michalek, J. E., Akhtar, F. Z., & Kiel, J. L. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.5.5663 · Cited by 82

Effects of acute hyperinsulinemia on testosterone serum concentrations in adult obese and normal-weight men

Pasquali, R., Macor, C., Vicennati, V., Iasio, F. R. D., Mesini, P., Boschi, S., Casimirri, F., & Vettor, R. (1997) · Metabolism · doi:10.1016/s0026-0495(97)90189-x · Cited by 77

Clinical implications of insulin resistance syndrome

Fournier, A. M. (1996) · The American Journal of Medicine · doi:10.1016/s0002-9343(96)80141-0 · Cited by 81

Clinical implications of insulin resistance syndromes

Davidson, M. B. (1995) · The American Journal of Medicine · doi:10.1016/s0002-9343(99)80191-0 · Cited by 78

Ethnic differences in Rotterdam criteria and metabolic risk factors in a multiethnic group of women with PCOS studied in Denmark

Glintborg, D., Mumm, H., HOUGAARD, D. M., Ravn, P., & Andersen, M. (2010) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2010.03873.x · Cited by 75

Type 2 diabetes is associated with increased bone mineral density in Mexican-American women

Kao, W. H. L., Kammerer, C. M., Schneider, J. L., Bauer, R. L., & Mitchell, B. D. (2003) · Archives of Medical Research · doi:10.1016/j.arcmed.2002.07.001 · Cited by 75

Insulin resistance, its consequences for the clinical course of the disease, and possibilities of correction in endometrial cancer

Berstein, L. M., Kvatchevskaya, J. O., Евгеньевна, П. Т., Kovalenko, I. G., Tsyrlina, E. V., Zimarina, T. S., Ourmantcheeva, A. F., Андреевич, А. Л., & Thijssen, J. H. H. (2004) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-004-0587-2 · Cited by 74

SHBG levels correlate with insulin resistance in postmenopausal women

Akın, F., Baştemir, M., Alkış, E., & Kaptanoğlu, B. (2008) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2007.09.023 · Cited by 74

Common Genetic Variation in the Sex Steroid Hormone-Binding Globulin (SHBG) Gene and Circulating SHBG Levels among Postmenopausal Women: The Multiethnic Cohort

Haiman, C. A., Riley, S. E., Freedman, M. L., Setiawan, V. W., Conti, D. V., & Marchand, L. L. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1417 · Cited by 71

Insulin Sensitivity and the Insulin-Like Growth Factor System in Prepubertal Boys with Premature Adrenarche

Denburg, M., Silfen, M. E., Manibo, A. M., Chin, D., Levine, L. S., Ferin, M., McMahon, D. J., Go, C., & Oberfield, S. E. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-020896 · Cited by 70

Dynamics of FSH-induced follicular growth in subfertile women: relationship with age, insulin resistance, oocyte yield and anti-Mullerian hormone

Fleming, R., Deshpande, N., Traynor, I., & Yates, R. W. S. (2006) · Human Reproduction · doi:10.1093/humrep/dei499 · Cited by 69

Effect of pioglitazone on glucose metabolism and luteinizing hormone secretion in women with polycystic ovary syndrome

Glintborg, D., Hermann, A. P., Andersen, M., Hagen, C., Beck‐Nielsen, H., Veldhuis, J. D., & Henriksen, J. E. (2006) · Fertility and Sterility · doi:10.1016/j.fertnstert.2005.12.067 · Cited by 68

Insulin Resistance, Hemostatic Factors, and Hormone Interactions in Pre- and Perimenopausal Women: SWAN

Sowers, M. R., Derby, C. A., Jannausch, M. L., Torréns, J. I., & Pasternak, R. C. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-030350 · Cited by 66

Peroxisome-Proliferator Receptor γ Represses Hepatic Sex Hormone-Binding Globulin Expression

Selva, D. M., & Hammond, G. L. (2009) · Endocrinology · doi:10.1210/en.2008-1289 · Cited by 66

Genetic variants of sex hormone-binding globulin and their biological consequences

Xita, N. V., & Tsatsoulis, A. A. (2009) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2009.08.025 · Cited by 63

Intrauterine Growth Retardation Predisposes to Insulin Resistance But Not to Hyperandrogenism in Young Women

Jaquet, D., Léger, J., Chevenne, D., Czernichow, P., & Lévy‐Marchal, C. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.11.6106 · Cited by 62

Short‐term effects of prednisolone and dexamethasone on circulating concentrations of leptin and sex hormone‐binding globulin in children being treated for acute lymphoblastic leukaemia

Wallace, A. M., Tucker, P., Williams, D. M., Hughes, I. A., & Ahmed, S. F. (2003) · Clinical Endocrinology · doi:10.1046/j.1365-2265.2003.01790.x · Cited by 57

Sex hormone‐binding globulin in gestational diabetes

Bartha, J. L., Comino‐Delgado, R., Romero‐Carmona, R., & Gomez-Jaen, M. D. C. (2000) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1034/j.1600-0412.2000.079010839.x · Cited by 57

Role of the insulin-like growth factors in the endocrine control of glucose homeostasis

LEWITT, M. S. (1994) · Diabetes Research and Clinical Practice · doi:10.1016/0168-8227(94)90121-x · Cited by 57

Association between hyperinsulinemia and endogenous androgen levels in peri- and postmenopausal women

Maturana, M. A., & Spritzer, P. M. (2002) · Metabolism · doi:10.1053/meta.2002.29997 · Cited by 56

POLYCYSTIC OVARY SYNDROME

Legro, R. S. (1999) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(05)70075-x · Cited by 56

Sex hormone-binding globulin as a marker for hyperinsulinemia and/or insulin resistance in obese children

Gascón, F., Valle, M., Martos, R., Rodríguez, F. J. R., Ríos, R., Montilla, P., & Cañete, R. (2000) · European Journal of Endocrinology · doi:10.1530/eje.0.1430085 · Cited by 55

Biological Variation of Homeostasis Model Assessment-Derived Insulin Resistance in Type 2 Diabetes

Jayagopal, V., Kilpatrick, E. S., Jennings, P. E., Hepburn, D. A., & Atkin, S. L. (2002) · Diabetes Care · doi:10.2337/diacare.25.11.2022 · Cited by 53

Polycystic ovary syndrome: relationship between insulin sensitivity ,sex hormone levels and ovarian stromal blood flow

Loverro, G., Vicino, M., Lorusso, F. P., Vimercati, A., Greco, P., & Selvaggi, L. E. (2001) · Gynecological Endocrinology · doi:10.1080/gye.15.2.142.149 · Cited by 52

Optimal use of hormone determinations in the biochemical diagnosis of the polycystic ovary syndrome

Koskinen, P., Penttilä, T.-A., Anttila, L., Erkkola, R., & Irjala, K. (1996) · Fertility and Sterility · doi:10.1016/s0015-0282(16)58146-1 · Cited by 51

Hemoglobin A1c as a tool for the diagnosis of type 2 diabetes in 208 premenopausal women with polycystic ovary syndrome

Magnussen, L. V., Mumm, H., Andersen, M., & Glintborg, D. (2011) · Fertility and Sterility · doi:10.1016/j.fertnstert.2011.08.035 · Cited by 51

Comparative studies on the regulation of insulin-like growth factor-binding protein-1 (IGFBP-1) and sex hormone-binding globulin (SHBG) production by insulin and insulin-like growth factors in human hepatoma cells

Kalme, T., Koistinen, H. K., Loukovaara, M. J., Koistinen, R. A., & Leinonen, P. J. (2003) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/s0960-0760(03)00268-1 · Cited by 49

Insulin, leptin, IGF-I and insulin-dependent protein concentrations after insulin-sensitizing therapy in obese women with polycystic ovary syndrome

Kowalska, I., Kinalski, M., Strączkowski, M., Wolczyski, S., & Kinalska, I. (2001) · European Journal of Endocrinology · doi:10.1530/eje.0.1440509 · Cited by 49

Genomic variants in polycystic ovary syndrome

Luque‐Ramírez, M., Millán, J. L. S., & Escobar-Morreale, H. F. (2005) · Clinica Chimica Acta · doi:10.1016/j.cca.2005.10.017 · Cited by 48

Relative androgenicity, blood pressure levels, and cardiovascular risk factors in young healthy women*

Mantzoros, C. S., Georgiadis, E. I., Young, R. F., Evagelopoulou, C., Khoury, S., Katsilambros, N. L., & Sowers, J. R. (1995) · American Journal of Hypertension · doi:10.1016/0895-7061(95)00051-p · Cited by 47

The aging male: testosterone deficiency and testosterone replacement. An up-date

Alexandersen, P., & Christiansen, C. (2003) · Atherosclerosis · doi:10.1016/s0021-9150(03)00242-9 · Cited by 45

Sexual dimorphism in the maturation of the pituitary-gonadal axis, assessed by GnRH agonist challenge

Potau, N., Ibáñez, L., Sentis, M., & Carrascosa, A. (1999) · European Journal of Endocrinology · doi:10.1530/eje.0.1410027 · Cited by 45

Serum ghrelin, leptin and resistin levels in adolescent girls with polycystic ovary syndrome

Bıdecı, A., Çamurdan, M. O., Yeşilkaya, E., Demirel, F., & Cınaz, P. (2008) · Journal of obstetrics and gynaecology research · doi:10.1111/j.1447-0756.2008.00819.x · Cited by 41

Sex Hormone–Binding Globulin and Testosterone in Individuals With Childhood Diabetes

Danielson, K. K., Drum, M. L., & Lipton, R. B. (2008) · Diabetes Care · doi:10.2337/dc07-2169 · Cited by 43

Changes in testosterone related to body composition in late midlife: Findings from the 1946 British birth cohort study

Bann, D., Wu, F. C. W., Keevil, B. G., Lashen, H., Adams, J. E., Hardy, R., Terrera, G. M., Kuh, D. J., Ben‐Shlomo, Y., & Ong, K. K. (2015) · Obesity · doi:10.1002/oby.21092 · Cited by 41

Insulin Resistance, Premature Adrenarche, and a Risk of the Polycystic Ovary Syndrome (PCOS)

Ibáñez, L., Potau, N., & Carrascosa, A. (1998) · Trends in Endocrinology and Metabolism · doi:10.1016/s1043-2760(98)00014-9 · Cited by 41

Comparative effects of GH, IGF‐I and insulin on serum sex hormone binding globulin

Gafny, M., Silbergeld, A., Kilnger, B., Wasserman, M., & Laron, Z. (1994) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1994.tb02526.x · Cited by 39

Sex hormone binding globulin concentration as a prepubertal marker for hyperinsulinaemia in obesity

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Haffner, S. M. (1997) · Journal of Hypertension · doi:10.1097/00004872-199715011-00003 · Cited by 35

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Sex hormone-binding globulin genetic variation: associations with type 2 diabetes mellitus and polycystic ovary syndrome.

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Relationship Between Sex Hormone-binding Globulin and Insulin Resistance in Man

Guo-hon, W. (2014) · Biaoji mianyi fenxi yu linchuang