Nestler, John E.

Clomiphene, metformin, or both for infertility in the polycystic ovary syndrome

Legro, R. S., Barnhart, H. X., Schlaff, W. D., Carr, B. R., Diamond, M. P., Carson, S. A., Steinkampf, M. P., Coutifaris, C., McGovern, P. G., Cataldo, N. A., et al. (2007) · New England Journal of Medicine

Ovarian function and disordersReproductive Health and Technologies

Cited by 1,027

Prevalence and Characteristics of the Metabolic Syndrome in Women with Polycystic Ovary Syndrome

Apridonidze, T., Essah, P. A., Iuorno, M. J., & Nestler, J. E. (2005) · The Journal of Clinical Endocrinology & Metabolism

Ovarian function and disordersDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 931

A Direct Effect of Hyperinsulinemia on Serum Sex Hormone-Binding Globulin Levels in Obese Women with the Polycystic Ovary Syndrome*

NESTLER, J. E., POWERS, L. P., MATT, D. W., STEINGOLD, K. A., PLYMATE, S. R., RITTMASTER, R. S., CLORE, J. N., & BLACKARD, W. G. (1991) · The Journal of Clinical Endocrinology & Metabolism

Ovarian function and disordersHormonal and reproductive studies

Cited by 815

Decreases in Ovarian Cytochrome P450c17α Activity and Serum Free Testosterone after Reduction of Insulin Secretion in Polycystic Ovary Syndrome

Nestler, J. E., & Jakubowicz, D. J. (1996) · New England Journal of Medicine

Ovarian function and disordersDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 743

Insulin Stimulates Testosterone Biosynthesis by Human Thecal Cells from Women with Polycystic Ovary Syndrome by Activating Its Own Receptor and Using Inositolglycan Mediators as the Signal Transduction System1

Nestler, J. E., Jakubowicz, D. J., Falcon de Vargas, A., Brik, C., Quintero, N., & Medina, F. (1998) · The Journal of Clinical Endocrinology & Metabolism

Ovarian function and disordersReproductive Biology and Fertility

Cited by 617

Ovulatory and Metabolic Effects of d-Chiro-Inositol in the Polycystic Ovary Syndrome

Nestler, J. E., Jakubowicz, D. J., Reamer, P., Gunn, R. D., & Allan, G. (1999) · New England Journal of Medicine

Ovarian function and disordersDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 518

Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations

Hayes, M. G., Urbanek, M., Ehrmann, D. A., Armstrong, L. L., Lee, J. Y., Sisk, R., Karaderi, T., Barber, T. M., McCarthy, M. I., Franks, S., et al. (2015) · Nature Communications

Ovarian function and disordersGenetic Associations and Epidemiology

Cited by 478

Dehydroepiandrosterone reduces serum low density lipoprotein levels and body fat but does not alter insulin sensitivity in normal men.

NESTLER, J. E., BARLASCINI, C. O., CLORE, J. N., & BLACKARD, W. G. (1988) · The Journal of Clinical Endocrinology & Metabolism

Hormonal and reproductive studiesAdrenal Hormones and Disorders

Cited by 414

Suppression of Serum Insulin by Diazoxide Reduces Serum Testosterone Levels in Obese Women with Polycystic Ovary Syndrome*

NESTLER, J. E., BARLASCINI, C. O., MATT, D. W., STEINGOLD, K. A., PLYMATE, S. R., CLORE, J. N., & BLACKARD, W. G. (1989) · The Journal of Clinical Endocrinology & Metabolism

Ovarian function and disordersDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 338

Metformin for the treatment of the polycystic ovary syndrome

Nestler, J. E. (2008) · New England Journal of Medicine

Ovarian function and disordersDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 313

Effects of metformin and rosiglitazone, alone and in combination, in nonobese women with polycystic ovary syndrome and normal indices of insulin sensitivity

Baillargeon, J.-P., Jakubowicz, D. J., Iuorno, M. J., Jakubowicz, S., & Nestler, J. E. (2004) · Fertility and Sterility

Ovarian function and disordersDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 300

Total Testosterone Assays in Women with Polycystic Ovary Syndrome: Precision and Correlation with Hirsutism

Legro, R. S., Schlaff, W. D., Diamond, M. P., Coutifaris, C., Casson, P. R., Brzyski, R. G., Christman, G. M., Trussell, J. C., Krawetz, S. A., Snyder, P. J., et al. (2010) · The Journal of Clinical Endocrinology & Metabolism

Ovarian function and disordersClinical Laboratory Practices and Quality Control

Cited by 213

Sex hormone-binding globulin: a marker for hyperinsulinemia and/or insulin resistance?

Nestler, J. E. (1993) · The Journal of Clinical Endocrinology & Metabolism

Diabetes, Cardiovascular Risks, and LipoproteinsOvarian function and disorders

Cited by 201

Sex hormone-binding globulin and type 2 diabetes mellitus

Le, T. N., Nestler, J. E., Strauss, J. F., & Wickham, E. P. (2012) · Trends in Endocrinology & Metabolism

Hormonal and reproductive studiesAdipokines, Inflammation, and Metabolic Diseases

Cited by 191

Effects of d-chiro-inositol in lean women with the polycystic ovary syndrome

Iuorno, M. J., Jakubowicz, D. J., Baillargeon, J.-P., Dillon, P., Gunn, R. D., Allan, G., & Nestler, J. E. (2002) · Endocrine Practice

Ovarian function and disordersDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 188

Inositols: From Established Knowledge to Novel Approaches

Dinicola, S., Unfer, V., Facchinetti, F., Soulage, C. O., Greene, N. D., Bizzarri, M., Laganà, A. S., Chan, S.-Y., Bevilacqua, A., Pkhaladze, L., et al. (2021) · International Journal of Molecular Sciences

Ovarian function and disordersReproductive Biology and Fertility

Cited by 154

Reflections on inositol(s) for PCOS therapy: steps toward success

Nestler, J. E., & Unfer, V. (2015) · Gynecological Endocrinology

Ovarian function and disordersReproductive Biology and Fertility

Cited by 106

Inositols in polycystic ovary syndrome: An overview on the advances

Facchinetti, F., Unfer, V., Dewailly, D., Kamenov, Z. A., Diamanti-Kandarakis, E., Laganà, A. S., Nestler, J. E., & Soulage, C. O. (2020) · Trends in Endocrinology & Metabolism

Ovarian function and disordersReproductive Biology and Fertility

Cited by 102

Experts’ opinion on inositols in treating polycystic ovary syndrome and non-insulin dependent diabetes mellitus: a further help for human reproduction and beyond

Facchinetti, F., Appetecchia, M., Aragona, C., Bevilacqua, A., Bezerra Espinola, M. S., Bizzarri, M., D’Anna, R., Dewailly, D., Diamanti-Kandarakis, E., Hernández Marín, I., et al. (2020) · Expert Opinion on Drug Metabolism & Toxicology

Ovarian function and disordersReproductive Biology and Fertility

Cited by 63

Sleep-associated fall in glucose disposal and hepatic glucose output in normal humans. Putative signaling mechanism linking peripheral and hepatic events

Clore, J. N., Nestler, J. E., & Blackard, W. G. (1989) · Diabetes

Pancreatic function and diabetesDiabetes Management and Research

Cited by 62

Changes in glucose tolerance with metformin treatment in polycystic ovary syndrome: A retrospective analysis

Sharma, S. T., Wickham, E. P., & Nestler, J. E. (2007) · Endocrine Practice

Ovarian function and disordersDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 49

Risk of Cardiovascular Events in Mothers of Women with Polycystic Ovary Syndrome

Cheang, K. I., Nestler, J. E., & Futterweit, W. (2008) · Endocrine Practice

Ovarian function and disordersDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 31

Effect on insulin-stimulated release of D-chiro-inositol-containing inositolphosphoglycan mediator during weight loss in obese women with and without polycystic ovary syndrome

Cheang, K. I., Sistrun, S. N., Morel, K. S., & Nestler, J. E. (2016) · International Journal of Endocrinology

Ovarian function and disordersDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 2