Predictive Accuracy of Surrogate Indices for Hepatic and Skeletal Muscle Insulin Sensitivity

Muniyappa, Ranganath; Tella, Sri Harsha; Sortur, Shrayus; Mszar, Reed; Grewal, Shivraj; Abel, Brent S; Auh, Sungyoung; Chang, Douglas C; Krakoff, Jonathan; Skarulis, Monica C

doi:10.1210/js.2018-00206

Predictive Accuracy of Surrogate Indices for Hepatic and Skeletal Muscle Insulin Sensitivity

Context Surrogate indices of muscle and hepatic insulin sensitivity derived from an oral glucose tolerance test (OGTT) are frequently used in clinical studies. However, the predictive accuracy of these indices has not been validated. Design In this cross-sectional study, hyperinsulinemic-euglycem…