The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Reduction of optic nerve fibers in patients with Alzheimer disease identified by laser imaging
Open accessAbstract
In this case-control study, we compared the optic nerves (ONs) by clinical examination and scanning laser ophthalmoscopy (SLO) of 40 patients with Alzheimer disease (AD) and 50 controls. There was a reduction in the number of ON fibers in patients with AD, with a threefold greater odds ratio for a larger optic cup-to-disc ratio in patients with AD.
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In the citing paper
“However, in the last few decades it has been demonstrated that patients with AD often develop visual anomalies, which are correlated with abnormalities in the eye.”
From The role of microglia in retinal neurodegeneration: Alzheimer’s disease, parkinson, and glaucoma. (2017) · cites this paper as Danesh-Meyer et al., 2006
In the citing paper
“Among them, there is a reduction in the number of optic nerve head axons and a decrease in the thickness of the peripapillary and macular retinal nerve fiber layer (RNFL) (Tsai et al., 1991; Hedges et al., 1996; Danesh-Meyer et al., 2006; Iseri et al., 2006; Paquet et al., 2007; Garcia-Martin et al., 2014; Salobrar-Garcia et al., 2015; Salobrar-García et al., 2016c) (Table 1).”
From The role of microglia in retinal neurodegeneration: Alzheimer’s disease, parkinson, and glaucoma. (2017) · cites this paper as Danesh-Meyer et al., 2006
Citations
Cites
Optic-Nerve Degeneration in Alzheimer's Disease
Hinton, D. R., Sadun, A. A., Blanks, J. C., & Miller, C. A. (1986) · New England Journal of Medicine · doi:10.1056/nejm198608213150804 · Cited by 700
İşeri, P., Altıntaş, Ö., Tokay, T., & Yüksel, N. (2006) · Journal of Neuro-Ophthalmology · doi:10.1097/01.wno.0000204645.56873.26 · Cited by 402
Optic Nerve Damage in Alzheimer's Disease
Sadun, A. A., & Bassi, C. J. (1990) · Ophthalmology · doi:10.1016/s0161-6420(90)32621-0 · Cited by 351
Retinal ganglion cells in Alzheimer's disease and aging
Curcio, C., & Drucker, D. (1993) · Annals of Neurology · doi:10.1002/ana.410330305 · Cited by 323
Retinal ganglion cell degeneration in Alzheimer's disease
Blanks, J. C., Hinton, D. R., Sadun, A. A., & Miller, C. A. (1989) · Brain Research · doi:10.1016/0006-8993(89)90653-7 · Cited by 297
Caspase activation and amyloid precursor protein cleavage in rat ocular hypertension.
McKinnon, S. J., Lehman, D. M., Kerrigan, L. A., Merges, C. A., Pease, M. E., Kerrigan, D., Ransom, N. L., Tahzib, N. G., Reitsamer, H. A., Levkovitch-Verbin, H., et al. (2002) · PubMed · Cited by 296
Glaucoma ocular Alzheimer s disease
McKinnon, S. J. (2003) · Frontiers in bioscience · doi:10.2741/1172 · Cited by 229
Optic nerve head and nerve fiber layer in Alzheimer's disease
Tsai, C. S. (1991) · Archives of Ophthalmology · doi:10.1001/archopht.1991.01080020045040 · Cited by 163
Qiu, C. (2004) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2003.021493 · Cited by 115
Research works printed but not linked: 1
- Quigley HA, Nickells RW, Kerrigan LA, Pease ME, Thibault DJ, Zack DF. Retinal ganglion cell death in experimental glaucoma after axotomy occurs by apoptosis. Invest Ophthalmol Vis Sci 1995;36:774–786.
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The retina as a window to the brain—from eye research to CNS disorders
London, A., Benhar, I., & Schwartz, M. (2012) · Nature Reviews Neurology · doi:10.1038/nrneurol.2012.227 · Cited by 1,458
Retinal Abnormalities in Early Alzheimer’s Disease
Berisha, F., Feke, G. T., Trempe, C. L., McMeel, J. W., & Schepens, C. L. (2007) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.06-1029 · Cited by 505
The role of microglia in retinal neurodegeneration: Alzheimer’s disease, parkinson, and glaucoma.
Ramirez, A. I., de Hoz, R., Salobrar-Garcia, E., Salazar, J. J., Rojas, B., Ajoy, D., López-Cuenca, I., Rojas, P., Triviño, A., & Ramírez, J. M. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00214 · Cited by 466
Innovative diagnostic tools for early detection of Alzheimer's disease
Laske, C., Sohrabi, H. R., Frost, S. M., López-de-Ipiña, K., Garrard, P., Buscema, M., Dauwels, J., Soekadar, S. R., Mueller, S., Linnemann, C., et al. (2015) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2014.06.004 · Cited by 316
Amyloid-β Deposits Lead to Retinal Degeneration in a Mouse Model of Alzheimer Disease
Ning, A., Cui, J., To, E., Ashe, K. H., & Matsubara, J. (2008) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.08-1849 · Cited by 303
Metadata
- Authors
- Danesh-Meyer, H. V., Birch, H., Ku, J. Y.-F., Carroll, S., & Gamble, G.
- Affiliations
- University of Auckland (NZ)
- Venue
- Neurology
- Published
- 2006-11-28
- Volume
- 67
- Issue
- 10
- Pages
- 1852-1854
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- OpenAlex
- W2047691268
- Cited by
- 164
- References
- 9
- Citations by year
- 2026: 3 · 2025: 7 · 2024: 1 · 2023: 6 · 2022: 8 · 2021: 11 · 2020: 13 · 2019: 8 · 2018: 6 · 2017: 9 · 2016: 19 · 2015: 10 · 2014: 9 · 2013: 10 · 2012: 12
- FWCI
- 2.55
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- cc-by
- Locations
- Neurology (publishedVersion)
- PubMed (publishedVersion)
- ResearchSpace (University of Auckland) (submittedVersion, cc-by)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Ophthalmology › Glaucoma and retinal disorders
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Retinal Imaging and Analysis
- Keywords
- Alzheimer's disease, optic nerve fibers, optic nerve head, scanning laser ophthalmoscopy, cup-to-disc ratio, neurodegeneration, retinal imaging biomarkers
- MeSH terms
- Aged, Aged, 80 and over, Alzheimer Disease, Cell Count, Female, Humans, Male, Optic Nerve, Optic Nerve Diseases, Predictive Value of Tests, Retinal Ganglion Cells, Wallerian Degeneration, Case-Control Studies, Microscopy, Confocal, Ophthalmoscopes
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