Cited by 52Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatmentsCancer-related cognitive impairment studies

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Cued memory decline in biomarker-defined preclinical Alzheimer disease

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Papp, Kathryn V., Rentz, Dorene M., Mormino, Elizabeth C., Schultz, Aaron P., Amariglio, Rebecca E., Quiroz, Yakeel, Johnson, Keith A., Sperling, Reisa A.·2017·Neurology

DOI 10.1212/wnl.0000000000003812PMC PMC5386436

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Abstract

Objective: To determine whether a decline in cued recall is observable in the preclinical stage of Alzheimer disease (AD) in clinically normal older adults with elevated β-amyloid (Aβ) burden on PET imaging. Methods: Clinically normal older adults underwent baseline neuroimaging (PET to assess Aβ+/− status and MRI) and annual neuropsychological testing. Cox proportional hazards models were used to assess the relative risk of cued memory decline (drop of 1, 2, 3, or 4 points on the total score of the Free and Cued Selective Reminding Test) in relation to neuroimaging measures, functional status, age, sex, and education. Results: A total of 276 older adults (Clinical Dementia Rating = 0, mean Mini-Mental State Examination score = 29 ± 1.06) were followed up for a mean of 3.6 ± 1.2 years. Despite the infrequency of cued memory decline (only 19% of participants scored ≤46/48 in total recall by year 3), Aβ+ participants were 3.55 times (95% confidence interval = 1.77–7.12) more likely to exhibit decline in total recall (≤46/48) compared with their Aβ− peers. Furthermore, Aβ+ participants who scored ≤46/48 had smaller hippocampal volumes (t = 3.37, p = 0.001) and evidence of early functional decline, i.e., greater risk of progression to global Clinical Dementia Rating of 0.5 (χ2 = 14.30, p < 0.001), compared with their Aβ+ peers with intact total recall. Conclusions: Cued memory decline in healthy older adults may be particularly indicative of Aβ-related decline during the preclinical stage of AD and useful for identifying Aβ+ clinically normal individuals at greatest risk of short-term clinical progression.

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Morris, J. C. (1993) · Neurology · doi:10.1212/wnl.43.11.2412-a · Cited by 9,882
Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease
Sperling, R. A., Aisen, P. S., Beckett, L. A., Bennett, D. A., Craft, S., Fagan, A. M., Iwatsubo, T., Jack, C. R., Kaye, J., Montine, T. J., et al. (2011) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2011.03.003 · Cited by 7,155
Self-citation
Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound‐B
Klunk, W. E., Engler, H., Nordberg, A., Wang, Y., Blomqvist, G., Holt, D. P., Bergström, M., Savitcheva, I., Huang, G., Estrada, S., et al. (2004) · Annals of Neurology · doi:10.1002/ana.20009 · Cited by 4,496
Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS–ADRDA criteria
Dubois, B., Feldman, H. H., Jacova, C., DeKosky, S. T., Barberger-Gateau, P., Cummings, J., Delacourte, A., Galasko, D., Gauthier, S., Jicha, G., et al. (2007) · The Lancet Neurology · doi:10.1016/s1474-4422(07)70178-3 · Cited by 4,411
Population-Based Norms for the Mini-Mental State Examination by Age and Educational Level
Crum, R. M. (1993) · JAMA · doi:10.1001/jama.1993.03500180078038 · Cited by 2,958
The Medial Temporal Lobe and Recognition Memory
Eichenbaum, H., Yonelinas, A. P., & Ranganath, C. (2007) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.30.051606.094328 · Cited by 2,580
Revising the definition of Alzheimer's disease: a new lexicon
Dubois, B., Feldman, H. H., Jacova, C., Cummings, J. L., DeKosky, S. T., Barberger-Gateau, P., Delacourte, A., Frisoni, G., Fox, N. C., Galasko, D., et al. (2010) · The Lancet Neurology · doi:10.1016/s1474-4422(10)70223-4 · Cited by 1,869
Genuine memory deficits in dementia
Grober, E. H., & Herman Buschke, L. (1987) · Developmental Neuropsychology · doi:10.1080/87565648709540361 · Cited by 1,045
Amyloid Deposition Is Associated with Impaired Default Network Function in Older Persons without Dementia
Sperling, R. A., LaViolette, P. S., O'Keefe, K., O'Brien, J., Rentz, D. M., Pihlajamaki, M., Marshall, G., Hyman, B. T., Selkoe, D. J., Hedden, T., et al. (2009) · Neuron · doi:10.1016/j.neuron.2009.07.003 · Cited by 1,027
Self-citation
Synthesis and Evaluation of 11C-Labeled 6-Substituted 2-Arylbenzothiazoles as Amyloid Imaging Agents
Mathis, C. A., Wang, Y., Holt, D. P., Huang, G.-F., Debnath, M. L., & Klunk, W. E. (2003) · Journal of Medicinal Chemistry · doi:10.1021/jm030026b · Cited by 976

Show all 40 references

Research works printed but not linked: 2

Cox PR. Life Tables. New York: John Wiley & Sons; 1972.
10.1037/0882-7974.12.1.183 · DOI

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Johnson, S. C., Suárez‐Calvet, M., Suridjan, I., Minguillón, C., Gispert, J. D., Jonaitis, E., Michna, A., Carboni, M., Bittner, T., Rabe, C., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22613084
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Gagliardi, G. P., Corte, V. L., Houot, M., Dubois, B., & Barba, G. D. (2026) · medRxiv · doi:10.64898/2026.01.30.26345197
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Ayed, I. B. (2021) · theses.fr (ABES) · doi:10.70675/cfcbef75zedfdz48dez80f3zd2a2d4cabbd6
Association between amyloid-β deposition and cognitive function in cognitively normal adults: a multilevel meta-analysis
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Authors: Papp, K. V., Rentz, D. M., Mormino, E. C., Schultz, A. P., Amariglio, R. E., Quiroz, Y., Johnson, K. A., & Sperling, R. A.
Affiliations: Brigham and Women's Hospital (US)
ORCID: Papp, Kathryn V.
Rentz, Dorene M.
Mormino, Elizabeth C.
Schultz, Aaron P.
Amariglio, Rebecca E.
Quiroz, Yakeel
Johnson, Keith A.
Sperling, Reisa A.
Venue: Neurology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2017-04-11
Volume: 88
Issue: 15
Pages: 1431-1438
ISSN: 0028-3878 (ISSN-L)
1526-632X
DOI: 10.1212/wnl.0000000000003812
PMC: PMC5386436
OpenAlex: W2592328671
Cited by: 52
References: 40
Citations by year: 2026: 2 · 2025: 2 · 2024: 7 · 2023: 4 · 2022: 6 · 2021: 11 · 2020: 8 · 2019: 4 · 2018: 7 · 2017: 1
FWCI: 4.49
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Neurology (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: Bristol-Myers Squibb
Eli Lilly and Company
Pfizer
Sanofi
Biogen
Eisai
H. Lundbeck A/S
National Institutes of Health (5u01ag024904-10)
Genentech
National Institute on Aging (U01-AG-024904, R01AG026484, R21AG038994, K24AG035007, R01AG027435, R01AG037497, P50AG005134, U19AG010483, U01AG032438, K23AG053422, R01AG034556, P01AG036694)
National Institute of Mental Health (R01MH090291)
National Institute of Biomedical Imaging and Bioengineering (R01EB014894)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
Health Sciences › Medicine › Oncology › Cancer-related cognitive impairment studies
Keywords: preclinical Alzheimer's disease, cued recall, memory decline, amyloid PET, amyloid burden, hippocampal volume, Free and Cued Selective Reminding Test, Clinical Dementia Rating, functional decline
MeSH terms: Aged, Aged, 80 and over, Alzheimer Disease, Amyloid, Aniline Compounds, Cues, Female, Hippocampus, Humans, Longitudinal Studies, Magnetic Resonance Imaging, Male, Memory Disorders, Mental Status Schedule, Neuropsychological Tests, Mental Recall, Thiazoles, Biomarkers, Disease Progression, Positron-Emission Tomography

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Cued memory decline in biomarker-defined preclinical Alzheimer disease

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