The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Association of Pace of Aging Measured by Blood-Based DNA Methylation With Age-Related Cognitive Impairment and Dementia
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“In observational studies with long-term follow-up, individuals with slower DunedinPACE are better-off on a range of healthspan metrics, including showing reduced incidence of morbidity and increased survival24,29.”
From Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial (2023) · cites this paper as [29]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“The methods proposed to quantify biological aging analyzed in this study are predictive of aging-related health decline and mortality.”
From Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial (2023) · cites this paper as [29]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“All three measures have evidence for validity as biomarkers of aging, in particular, evidence of association with aging-related morbidity and mortality and with exposures associated with shortened healthy lifespan24,29,30.”
From Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial (2023) · cites this paper as [29]
Experimental — accuracy not yet measuredIn the citing paper
“DunedinPACE has high test–retest reliability and shows strong associations with healthspan endpoints in validation analyses24,29.”
From Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial (2023) · cites this paper as [29]
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Cites
The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment
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DNA methylation age of human tissues and cell types
Horvath, S. (2013) · Genome Biology · doi:10.1186/gb-2013-14-10-r115 · Cited by 7,075
DNA methylation arrays as surrogate measures of cell mixture distribution
Houseman, E. A., Accomando, W. P., Koestler, D. C., Christensen, B. C., Marsit, C. J., Nelson, H. H., Wiencke, J. K., & Kelsey, K. T. (2012) · BMC Bioinformatics · doi:10.1186/1471-2105-13-86 · Cited by 3,175
Geroscience: Linking Aging to Chronic Disease
Kennedy, B. K., Berger, S. L., Brunet, A., Campisi, J., Cuervo, A. M., Epel, E. S., Franceschi, C., Lithgow, G. J., Morimoto, R. I., Pessin, J. E., et al. (2014) · Cell · doi:10.1016/j.cell.2014.10.039 · Cited by 2,764
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DNA methylation GrimAge strongly predicts lifespan and healthspan
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Incidence of dementia over three decades in the Framingham heart study
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Cited by
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Waziry, R., Ryan, C. P., Corcoran, D. L., Huffman, K. M., Kobor, M. S., Kothari, M., Graf, G. H., Kraus, V. B., Kraus, W. E., Lin, D. T. S., et al. (2023) · Nature Aging · doi:10.1038/s43587-022-00357-y · Cited by 217
Self-citationWhitman, E. T., Elliott, M. L., Knodt, A. R., Abraham, W. C., Anderson, T. J., Cutfield, N. J., Hogan, S., Ireland, D., Melzer, T. R., Ramrakha, S., et al. (2025) · Nature Aging · doi:10.1038/s43587-025-00897-z · Cited by 37
Self-citation
Metadata
- Authors
- Sugden, K., Caspi, A., Elliott, M. L., Bourassa, K. J., Chamarti, K., Corcoran, D. L., Hariri, A. R., Houts, R. M., Kothari, M., Kritchevsky, S., Kuchel, G. A., Mill, J. S., Williams, B. S., Belsky, D. W., Moffitt, T. E., & Initiative*, F. T. A. D. N.
- Venue
- Neurology
- Published
- 2022-09-27
- Volume
- 99
- Issue
- 13
- ISSN
- 0028-3878
- 1526-632X
- PMC
- PMC9576288
- Cited by
- 156
- References
- 13
- Language
- en
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