Cited by 1,410Dementia and Cognitive Impairment ResearchHistorical and Modern Theater StudiesNeurological Disease Mechanisms and Treatments

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Practice parameter: Diagnosis of dementia (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology

Knopman, D. S., DeKosky, S. T., Cummings, J. L., Chui, H., Corey–Bloom, J., Relkin, N., Small, G. W., Miller, B., Stevens, J. C.·2001·Neurology

DOI 10.1212/wnl.56.9.1143

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Abstract

Objective To update the 1994 practice parameter for the diagnosis of dementia in the elderly. Background The AAN previously published a practice parameter on dementia in 1994. New research and clinical developments warrant an update of some aspects of diagnosis. Methods Studies published in English from 1985 through 1999 were identified that addressed four questions: 1) Are the current criteria for the diagnosis of dementia reliable? 2) Are the current diagnostic criteria able to establish a diagnosis for the prevalent dementias in the elderly? 3) Do laboratory tests improve the accuracy of the clinical diagnosis of dementing illness? 4) What comorbidities should be evaluated in elderly patients undergoing an initial assessment for dementia? Recommendations Based on evidence in the literature, the following recommendations are made. 1) The DSM-III-R definition of dementia is reliable and should be used (Guideline). 2) The National Institute of Neurologic, Communicative Disorders and Stroke--AD and Related Disorders Association (NINCDS-ADRDA) or the Diagnostic and Statistical Manual, 3rd edition, revised (DSM-IIIR) diagnostic criteria for AD and clinical criteria for Creutzfeldt--Jakob disease (CJD) have sufficient reliability and validity and should be used (Guideline). Diagnostic criteria for vascular dementia, dementia with Lewy bodies, and frontotemporal dementia may be of use in clinical practice (Option) but have imperfect reliability and validity. 3) Structural neuroima…

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Authors: Knopman, D. S., DeKosky, S. T., Cummings, J. L., Chui, H., Corey–Bloom, J., Relkin, N., Small, G. W., Miller, B., & Stevens, J. C.
Affiliations: University of Southern California (US)
From the Department of Neurology (Dr. Knopman), Mayo Clinic, Rochester, MN; Departments of Neurology and Psychiatry (Dr. DeKosky), University of Pittsburgh, PA; Departments of Neurology and Psychiatry & Biobehavioral Science (Dr. Cummings), University of California at Los Angeles; Department of Neurology (Dr. Chui), University of Southern California, Los Angeles; Department of Neurosciences (Dr. Corey–Bloom), University of California at San Diego; Department of Neurology and Neuroscience (Dr....
ORCID: Knopman, D. S.
DeKosky, S. T.
Cummings, J. L.
Chui, H.
Relkin, N.
Small, G. W.
Miller, B.
Venue: Neurology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2001-05-08
Volume: 56
Issue: 9
Pages: 1143-1153
ISSN: 0028-3878 (ISSN-L)
1526-632X
DOI: 10.1212/wnl.56.9.1143
OpenAlex: W4210965305
Cited by: 1,410
References: 142
Citations by year: 2026: 23 · 2025: 32 · 2024: 51 · 2023: 34 · 2022: 52 · 2021: 44 · 2020: 74 · 2019: 40 · 2018: 46 · 2017: 54 · 2016: 49 · 2015: 64 · 2014: 60 · 2013: 67 · 2012: 68
FWCI: 37.05
Type: journal article
Language: en
Open access: closed
Locations: Neurology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Social Sciences › Psychology › Clinical Psychology › Historical and Modern Theater Studies
Life Sciences › Neuroscience › Neurology › Neurological Disease Mechanisms and Treatments
Keywords: dementia diagnosis, diagnostic criteria, Alzheimer's disease, Creutzfeldt-Jakob disease, vascular dementia, dementia with Lewy bodies, frontotemporal dementia, NINCDS-ADRDA criteria, DSM-III-R, diagnostic reliability, structural neuroimaging, depression screening, vitamin B12 deficiency, hypothyroidism, syphilis screening
MeSH terms: Dementia, Humans

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