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Practice parameter: Diagnosis of dementia (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology
Abstract
Objective To update the 1994 practice parameter for the diagnosis of dementia in the elderly. Background The AAN previously published a practice parameter on dementia in 1994. New research and clinical developments warrant an update of some aspects of diagnosis. Methods Studies published in English from 1985 through 1999 were identified that addressed four questions: 1) Are the current criteria for the diagnosis of dementia reliable? 2) Are the current diagnostic criteria able to establish a diagnosis for the prevalent dementias in the elderly? 3) Do laboratory tests improve the accuracy of the clinical diagnosis of dementing illness? 4) What comorbidities should be evaluated in elderly patients undergoing an initial assessment for dementia? Recommendations Based on evidence in the literature, the following recommendations are made. 1) The DSM-III-R definition of dementia is reliable and should be used (Guideline). 2) The National Institute of Neurologic, Communicative Disorders and Stroke--AD and Related Disorders Association (NINCDS-ADRDA) or the Diagnostic and Statistical Manual, 3rd edition, revised (DSM-IIIR) diagnostic criteria for AD and clinical criteria for Creutzfeldt--Jakob disease (CJD) have sufficient reliability and validity and should be used (Guideline). Diagnostic criteria for vascular dementia, dementia with Lewy bodies, and frontotemporal dementia may be of use in clinical practice (Option) but have imperfect reliability and validity. 3) Structural neuroima…
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“Major consensus dementia investigation guidelines all recommend structural brain imaging as part of the investigation of bvFTD (Knopman et al. , 2001; Filippi et al. , 2012; Soucy et al. , 2013).”
From Recommendations to distinguish behavioural variant frontotemporal dementia from psychiatric disorders (2020) · cites this paper as Knopman et al. , 2001
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Metadata
- Authors
- Knopman, D. S., DeKosky, S. T., Cummings, J. L., Chui, H., Corey–Bloom, J., Relkin, N., Small, G. W., Miller, B., & Stevens, J. C.
- Affiliations
- University of Southern California (US)
- From the Department of Neurology (Dr. Knopman), Mayo Clinic, Rochester, MN; Departments of Neurology and Psychiatry (Dr. DeKosky), University of Pittsburgh, PA; Departments of Neurology and Psychiatry & Biobehavioral Science (Dr. Cummings), University of California at Los Angeles; Department of Neurology (Dr. Chui), University of Southern California, Los Angeles; Department of Neurosciences (Dr. Corey–Bloom), University of California at San Diego; Department of Neurology and Neuroscience (Dr....
- Venue
- Neurology
- Published
- 2001-05-08
- Volume
- 56
- Issue
- 9
- Pages
- 1143-1153
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- OpenAlex
- W4210965305
- Cited by
- 1,410
- References
- 142
- Citations by year
- 2026: 23 · 2025: 32 · 2024: 51 · 2023: 34 · 2022: 52 · 2021: 44 · 2020: 74 · 2019: 40 · 2018: 46 · 2017: 54 · 2016: 49 · 2015: 64 · 2014: 60 · 2013: 67 · 2012: 68
- FWCI
- 37.05
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neurology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Social Sciences › Psychology › Clinical Psychology › Historical and Modern Theater Studies
- Life Sciences › Neuroscience › Neurology › Neurological Disease Mechanisms and Treatments
- Keywords
- dementia diagnosis, diagnostic criteria, Alzheimer's disease, Creutzfeldt-Jakob disease, vascular dementia, dementia with Lewy bodies, frontotemporal dementia, NINCDS-ADRDA criteria, DSM-III-R, diagnostic reliability, structural neuroimaging, depression screening, vitamin B12 deficiency, hypothyroidism, syphilis screening
- MeSH terms
- Dementia, Humans
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