The DOI matches its Crossref record; 119 of the 119 references it cites were found in a registry or an index.
Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network
Abstract
Neuronal subtype specification in the vertebrate neural tube is one of the best-studied examples of embryonic pattern formation. Distinct neuronal subtypes are generated in a precise spatial order from progenitor cells according to their location along the anterior-posterior and dorsal-ventral axes. Underpinning this organization is a complex network of multiple extrinsic and intrinsic factors. This review focuses on the molecular mechanisms and general strategies at play in ventral regions of the forming spinal cord, where sonic hedgehog-based morphogen signaling is a key determinant. We discuss recent advances in our understanding of these events and highlight unresolved questions.
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Cites
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Self-citationNeuronal specification in the spinal cord: inductive signals and transcriptional codes
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Vertebrate Smoothened functions at the primary cilium
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Cited by
The mechanisms of Hedgehog signalling and its roles in development and disease
Briscoe, J., & Thérond, P. P. (2013) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3598 · Cited by 1,751
Self-citationThe Primary Cilium as a Complex Signaling Center
Berbari, N. F., O'Connor, A. K., Haycraft, C. J., & Yoder, B. K. (2009) · Current Biology · doi:10.1016/j.cub.2009.05.025 · Cited by 621
Primary Cilia and Mammalian Hedgehog Signaling
Bangs, F., & Anderson, K. V. (2017) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a028175 · Cited by 642
Mechanisms and functions of Hedgehog signalling across the metazoa
Ingham, P. W., Nakano, Y., & Seger, C. (2011) · Nature Reviews Genetics · doi:10.1038/nrg2984 · Cited by 605
A highlight on Sonic hedgehog pathway
Carballo, G. B., Honorato, J. R., de Lopes, G. P. F., & Spohr, T. C. L. D. S. E. (2018) · Cell Communication and Signaling · doi:10.1186/s12964-018-0220-7 · Cited by 460
Metadata
- Authors
- Dessaud, E., McMahon, A. P., & Briscoe, J.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 2008-08-01
- Volume
- 135
- Issue
- 15
- Pages
- 2489-2503
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2075994912
- Cited by
- 734
- References
- 119
- FWCI
- 18.24
- Type
- journal article
- Language
- en
- Open access
- closed
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- Dessaud, E., McMahon, A. P., & Briscoe, J. (2008). Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network. Development. https://doi.org/10.1242/dev.009324
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