The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Reiterated Wnt signaling during zebrafish neural crest development
Abstract
While Wnt/β-catenin signaling is known to be involved in the development of neural crest cells in zebrafish, it is unclear which Wnts are involved, and when they are required. To address these issues we employed a zebrafish line that was transgenic for an inducible inhibitor of Wnt/β-catenin signaling, and inhibited endogenous Wnt/β-catenin signaling at discrete times in development. Using this approach, we defined a critical period for Wnt signaling in the initial induction of neural crest,which is distinct from the later period of development when pigment cells are specified from neural crest. Blocking Wnt signaling during this early period interfered with neural crest formation without blocking development of dorsal spinal neurons. Transplantation experiments suggest that neural crest precursors must directly transduce a Wnt signal. With regard to identifying which endogenous Wnt is responsible for this initial critical period, we established that wnt8 is expressed in the appropriate time and place to participate in this process. Supporting a role for Wnt8, blocking its function with antisense morpholino oligonucleotides eliminates initial expression of neural crest markers. Taken together, these results demonstrate that Wnt signals are critical for the initial induction of zebrafish neural crest and suggest that this signaling pathway plays reiterated roles in its development.
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Citations
Cites
Dorsky, R. I., Sheldahl, L. C., & Moon, R. T. (2002) · Developmental Biology · doi:10.1006/dbio.2001.0515 · Cited by 287 · cited 2×
“Transgenic TOPdGFP fish (Tg (TOP:dGFP)w25) express d2EGFP under control of four Lef binding sites and have been described previously (Dorsky et al., 2002).”
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Cited by
Goessling, W., North, T. E., Loewer, S., Lord, A. M., Lee, S., Stoick-Cooper, C. L., Weidinger, G., Puder, M., Daley, G. Q., Moon, R. T., et al. (2009) · Cell · doi:10.1016/j.cell.2009.01.015 · Cited by 699
Self-citationBone morphogenetic protein signalling and vertebrate nervous system development
Liu, A., & Niswander, L. A. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1805 · Cited by 332
Essential role of non-canonical Wnt signalling in neural crest migration
De Calisto, J., Araya, C., Marchant, L., Riaz, C. F., & Mayor, R. (2005) · Development · doi:10.1242/dev.01857 · Cited by 304
Sequential actions of Pax3 and Pax7 drive xanthophore development in zebrafish neural crest
Minchin, J. E. N., & Hughes, S. M. (2008) · Developmental Biology · doi:10.1016/j.ydbio.2008.02.058 · Cited by 155
β-catenin/Wnt signaling controls progenitor fate in the developing and regenerating zebrafish retina
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Li, W., & Cornell, R. A. (2007) · Developmental Biology · doi:10.1016/j.ydbio.2006.12.042 · Cited by 147
Zebrafish Foxd3 is required for development of a subset of neural crest derivatives
Lister, J. A., Cooper, C., Nguyen, K., Modrell, M., Grant, K., & Raible, D. W. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2005.11.014 · Cited by 138
Self-citationTfap2a and Foxd3 regulate early steps in the development of the neural crest progenitor population
Wang, W.-D., Melville, D. B., Montero-Balaguer, M., Hatzopoulos, A. K., & Knapik, E. W. (2011) · Developmental Biology · doi:10.1016/j.ydbio.2011.09.019 · Cited by 99
Montero‐Balaguer, M., Lang, M. R., Sachdev, S. W., Knappmeyer, C., Stewart, R. A., De La Guardia, A., Hatzopoulos, A. K., & Knapik, E. W. (2006) · Developmental Dynamics · doi:10.1002/dvdy.20959 · Cited by 95
EGFR is required for Wnt9a/Fzd9b signalling specificity in haematopoietic stem cells
Grainger, S., Nguyen, N., Richter, J., Setayesh, J., Lonquich, B., Oon, C. H., Wozniak, J. M., Barahona, R., Kamei, C. N., Houston, J., et al. (2019) · Nature Cell Biology · doi:10.1038/s41556-019-0330-5 · Cited by 60
An ongoing role for Wnt signaling in differentiating melanocytes in vivo
Vibert, L., Aquino, G., Gehring, I., Subkankulova, T., Schilling, T. F., Rocco, A., & Kelsh, R. N. (2017) · Pigment Cell & Melanoma Research · doi:10.1111/pcmr.12568 · Cited by 35
Quick, R. E., Buck, L. D., Parab, S., Tolbert, Z. R., & Matsuoka, R. L. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.735598 · Cited by 32
Regulation of zebrafish melanocyte development by ligand-dependent BMP signaling
Gramann, A. K., Venkatesan, A. M., Guerin, M., & Ceol, C. J. (2019) · eLife · doi:10.7554/elife.50047 · Cited by 30
Towards a gene regulatory network shaping the fins of the Princess cichlid
Ahi, E. P., & Sefc, K. M. (2018) · Scientific Reports · doi:10.1038/s41598-018-27977-y · Cited by 23
Metadata
- Authors
- Lewis, J. L., Bonner, J., Modrell, M., Ragland, J. W., Moon, R. T., Dorsky, R. I., & Raible, D. W.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 2004-03-15
- Volume
- 131
- Issue
- 6
- Pages
- 1299-1308
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2172096465
- Cited by
- 263
- References
- 1
- FWCI
- 8.53
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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