The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Cellular and molecular analyses of vascular tube and lumen formation in zebrafish
Abstract
Tube and lumen formation are essential steps in forming a functional vasculature. Despite their significance, our understanding of these processes remains limited, especially at the cellular and molecular levels. In this study, we analyze mechanisms of angioblast coalescence in the zebrafish embryonic midline and subsequent vascular tube formation. To facilitate these studies, we generated a transgenic line where EGFP expression is controlled by the zebrafish flk1 promoter. We find that angioblasts migrate as individual cells to form a vascular cord at the midline. This transient structure is stabilized by endothelial cell-cell junctions, and subsequently undergoes lumen formation to form a fully patent vessel. Downregulating the VEGF signaling pathway, while affecting the number of angioblasts, does not appear to affect their migratory behavior. Our studies also indicate that the endoderm, a tissue previously implicated in vascular development, provides a substratum for endothelial cell migration and is involved in regulating the timing of this process, but that it is not essential for the direction of migration. In addition, the endothelial cells in endodermless embryos form properly lumenized vessels, contrary to what has been previously reported in Xenopus and avian embryos. These studies provide the tools and a cellular framework for the investigation of mutations affecting vasculogenesis in zebrafish.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Initiation of hematopoiesis and vasculogenesis in murine yolk sac explants
Palis, J., McGrath, K., & Kingsley, P. (1995) · Blood · doi:10.1182/blood.v86.1.156.bloodjournal861156 · Cited by 198
Cited by
Haematopoietic stem cells derive directly from aortic endothelium during development
Bertrand, J. Y., Chi, N. C., Santoso, B., Teng, S., Stainier, D. Y. R., & Traver, D. (2010) · Nature · doi:10.1038/nature08738 · Cited by 1,025
Self-citationCombinatorial Regulation of Endothelial Gene Expression by Ets and Forkhead Transcription Factors
De Val, S., Chi, N. C., Meadows, S. M., Minovitsky, S., Anderson, J. P., Harris, I. S., Ehlers, M. L., Agarwal, P., Visel, A., Xu, S.-M., et al. (2008) · Cell · doi:10.1016/j.cell.2008.10.049 · Cited by 343
Self-citationDuchemin, A.-L., Vignes, H., & Vermot, J. (2019) · eLife · doi:10.7554/elife.44706 · Cited by 170
Radial glia regulate vascular patterning around the developing spinal cord
Matsuoka, R. L., Marass, M., Avdesh, A., Helker, C. S., Maischein, H.-M., Grosse, A. S., Kaur, H., Lawson, N. D., Herzog, W., & Stainier, D. Y. (2016) · eLife · doi:10.7554/elife.20253 · Cited by 84
Self-citationVegf signaling promotes vascular endothelial differentiation by modulating etv2 expression
Casie Chetty, S., Rost, M. S., Enriquez, J. R., Schumacher, J. A., Baltrunaite, K., Rossi, A., Stainier, D. Y. R., & Sumanas, S. (2017) · Developmental Biology · doi:10.1016/j.ydbio.2017.03.005 · Cited by 76
Self-citationLammert, E., & Axnick, J. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a006619 · Cited by 75
Tight Junction Protein 1a regulates pigment cell organisation during zebrafish colour patterning
Fadeev, A., Krauss, J., Frohnhöfer, H. G., Irion, U., & Nüsslein-Volhard, C. (2015) · eLife · doi:10.7554/elife.06545 · Cited by 60
tfec controls the hematopoietic stem cell vascular niche during zebrafish embryogenesis
Mahony, C. B., Fish, R. J., Pasche, C., & Bertrand, J. Y. (2016) · Blood · doi:10.1182/blood-2016-04-710137 · Cited by 58
Elucidation of the genetic causes of bicuspid aortic valve disease
Gehlen, J., Stundl, A., Debiec, R., Fontana, F., Krane, M., Sharipova, D., Nelson, C. P., Al-Kassou, B., Giel, A.-S., Sinning, J.-M., et al. (2023) · Cardiovascular Research · doi:10.1093/cvr/cvac099 · Cited by 51
Non-collagenous ECM proteins in blood vessel morphogenesis and cancer
Kostourou, V., & Papalazarou, V. (2014) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2014.02.018 · Cited by 41
Quick, R. E., Buck, L. D., Parab, S., Tolbert, Z. R., & Matsuoka, R. L. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.735598 · Cited by 32
Ghaffari, K., Pierce, L. X., Roufaeil, M., Gibson, I., Tae, K., Sahoo, S., Cantrell, J. R., Andersson, O., Lau, J., & Sakaguchi, T. F. (2021) · PLOS Genetics · doi:10.1371/journal.pgen.1009402 · Cited by 5
Pro-Angiogenetic Effects of Purified Extracts from Helix aspersa during Zebrafish Development
Zizioli, D., Mastinu, A., Muscò, A., Bonini, S. A., Finazzi, D., Avisani, R., Kron Morelli, G. B., Pecorelli, S., & Memo, M. (2022) · Current Issues in Molecular Biology · doi:10.3390/cimb44080232 · Cited by 4
Metadata
- Authors
- Jin, S.-W., Beis, D., Mitchell, T., Chen, J.-N., & Stainier, D. Y. R.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 2005-12-01
- Volume
- 132
- Issue
- 23
- Pages
- 5199-5209
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2072890764
- Cited by
- 863
- References
- 1
- FWCI
- 7.30
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
