The Caenorhabditis elegans gene lin-44 controls the polarity of asymmetric cell divisions

THE GENETICS OF CAENORHABDITIS ELEGANS

Brenner, S. (1974) · Genetics · doi:10.1093/genetics/77.1.71 · Cited by 14,985 · see citing works

The structure of the nervous system of the nematode <i>Caenorhabditis elegans</i>

White, J. G., Southgate, E., Thomson, J. N., & Brenner, S. (1986) · Philosophical Transactions of the Royal Society of London. B, Biological Sciences · doi:10.1098/rstb.1986.0056 · Cited by 5,589 · see citing works

The embryonic cell lineage of the nematode Caenorhabditis elegans

Sulston, J. E., Schierenberg, E., White, J. G., & Thomson, J. N. (1983) · Developmental Biology · doi:10.1016/0012-1606(83)90201-4 · Cited by 4,199 · see citing works

Post-embryonic cell lineages of the nematode, Caenorhabditis elegans

Sulston, J. E., & Horvitz, H. R. (1977) · Developmental Biology · doi:10.1016/0012-1606(77)90158-0 · Cited by 3,479 · see citing works

The Nematode Caenorhabditis elegans

Wood, W. B. (1988) · Cold Spring Harbor Laboratory eBooks · Cited by 2,821 · see citing works

Genetic Control of the Cell Division Cycle in Yeast

Hartwell, L. H., Culotti, J. G., Pringle, J. R., & Reid, B. J. (1974) · Science · doi:10.1126/science.183.4120.46 · Cited by 1,567 · see citing works

The origin of pattern and polarity in the Drosophila embryo

Johnston, D. S., & Nüsslein‐Volhard, C. (1992) · Cell · doi:10.1016/0092-8674(92)90466-p · Cited by 1,337 · see citing works

Mutant sensory cilia in the nematode Caenorhabditis elegans

Perkins, L. A., Hedgecock, E. M., Thomson, J. N., & Culotti, J. G. (1986) · Developmental Biology · doi:10.1016/0012-1606(86)90314-3 · Cited by 907 · see citing works

The postembryonic cell lineages of the hermaphrodite and male gonads in Caenorhabditis elegans

Kimble, J. E., & Hirsh, D. (1979) · Developmental Biology · doi:10.1016/0012-1606(79)90035-6 · Cited by 886 · see citing works

oskar organizes the germ plasm and directs localization of the posterior determinant nanos

Ephrussi, A., Dickinson, L. K., & Lehmann, R. (1991) · Cell · doi:10.1016/0092-8674(91)90137-n · Cited by 803 · see citing works

Electron microscopical reconstruction of the anterior sensory anatomy of the nematode caenorhabditis elegans

Ward, S. F., Thomson, N., White, J. G., & Brenner, S. (1975) · The Journal of Comparative Neurology · doi:10.1002/cne.901600305 · Cited by 782 · see citing works

NONDISJUNCTION MUTANTS OF THE NEMATODE CAENORHABDITIS ELEGANS

Hodgkin, J., Horvitz, H. R., & Brenner, S. (1979) · Genetics · doi:10.1093/genetics/91.1.67 · Cited by 769 · see citing works

GENETIC CONTROL OF THE CELL DIVISION CYCLE IN YEAST: V. GENETIC ANALYSIS OF cdc MUTANTS

Hartwell, L. H., Mortimer, R., Culotti, J. G., & Culotti, M. (1973) · Genetics · doi:10.1093/genetics/74.2.267 · Cited by 740 · see citing works

EGG-LAYING DEFECTIVE MUTANTS OF THE NEMATODE CAENORHABDITIS ELEGANS

Trent, C., Tsung, N., & Horvitz, H. R. (1983) · Genetics · doi:10.1093/genetics/104.4.619 · Cited by 729 · see citing works

staufen, a gene required to localize maternal RNAs in the Drosophila egg

Johnston, D. S., Beuchle, D., & Nüsslein‐Volhard, C. (1991) · Cell · doi:10.1016/0092-8674(91)90138-o · Cited by 631 · see citing works

CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae.

Adams, A. E., Johnson, D. I., Longnecker, R., Sloat, B. F., & Pringle, J. R. (1990) · The Journal of Cell Biology · doi:10.1083/jcb.111.1.131 · Cited by 603 · see citing works

The Caenorhabditis elegans male: Postembryonic development of nongonadal structures

Sulston, J. E., Albertson, D. G., & Thomson, J. N. (1980) · Developmental Biology · doi:10.1016/0012-1606(80)90352-8 · Cited by 584 · see citing works

Serotonin and Octopamine in the Nematode Caenorhabditis elegans

Horvitz, H. R., Chalfie, M., Trent, C., Sulston, J., & Evans, P. D. (1982) · Science · doi:10.1126/science.6805073 · Cited by 580 · see citing works

Regulation and cell autonomy during postembryonic development of Caenorhabditis elegans

Sulston, J. E., & White, J. G. (1980) · Developmental Biology · doi:10.1016/0012-1606(80)90353-x · Cited by 560 · see citing works

Mechanisms of asymmetric cell division: Two Bs or not two Bs, that is the question

Horvitz, H. R., & Herskowitz, I. (1992) · Cell · doi:10.1016/0092-8674(92)90468-r · Cited by 544 · see citing works

A genetic pathway for the development of the Caenorhabditis elegans HSN motor neurons

Desai, C. J., Garriga, G., Mclntire, S. L., & Horvitz, H. R. (1988) · Nature · doi:10.1038/336638a0 · Cited by 479 · see citing works

Axonal guidance mutants of Caenorhabditis elegans identified by filling sensory neurons with fluorescein dyes

Hedgecock, E. M., Culotti, J. G., Thomson, J. N., & Perkins, L. A. (1985) · Developmental Biology · doi:10.1016/0012-1606(85)90443-9 · Cited by 435 · see citing works

The let-23 gene necessary for Caenorhabditis elegans vulval induction encodes a tyrosine kinase of the EGF receptor subfamily

Aroian, R. V., Koga, M., Mendel, J., Ohshima, Y., & Sternberg, P. W. (1990) · Nature · doi:10.1038/348693a0 · Cited by 416 · see citing works

Caenorhabditis elegans ras gene let-60 acts as a switch in the pathway of vulval induction

Beitel, G. J., Clark, S. G., & Horvitz, H. (1990) · Nature · doi:10.1038/348503a0 · Cited by 414 · see citing works

Genetic control of bud site selection in yeast by a set of gene products that constitute a morphogenetic pathway

Chant, J., & Herskowitz, I. (1991) · Cell · doi:10.1016/0092-8674(91)90015-q · Cited by 407 · see citing works

let-60, a gene that specifies cell fates during C. elegans vulval induction, encodes a ras protein

Han, M., & Sternberg, P. W. (1990) · Cell · doi:10.1016/0092-8674(90)90495-z · Cited by 394 · see citing works

The gene lin-3 encodes an inductive signal for vulval development in C. elegans

Hill, R. J., & Sternberg, P. W. (1992) · Nature · doi:10.1038/358470a0 · Cited by 392 · see citing works

The nerve ring of the nematode Caenorhabditis elegans: Sensory input and motor output

Ware, R. W., Clark, D., Crossland, K. M., & Russell, R. L. (1975) · The Journal of Comparative Neurology · doi:10.1002/cne.901620106 · Cited by 296 · see citing works

A cell that dies during wild-type C. elegans development can function as a neuron in a ced-3 mutant.

Avery, L., & Horvitz, H. (1987) · Cell · doi:10.1016/0092-8674(87)90593-9 · Cited by 295 · see citing works

The posterior nervous system of the nematode Caenorhabditis elegans: serial reconstruction of identified neurons and complete pattern of synaptic interactions

Hall, D., & Russell, R. (1991) · The Journal of Neuroscience · doi:10.1523/jneurosci.11-01-00001.1991 · Cited by 268 · see citing works

Yeast BUD5, encoding a putative GDP-GTP exchange factor, is necessary for bud site selection and interacts with bud formation gene BEM1

Chant, J., Corrado, K., Pringle, J. R., & Herskowitz, I. (1991) · Cell · doi:10.1016/0092-8674(91)90016-r · Cited by 265 · see citing works

Multiple intercellular signalling systems control the development of the Caenorhabditis elegans vulva

Horvitz, H. R., & Sternberg, P. W. (1991) · Nature · doi:10.1038/351535a0 · Cited by 247 · see citing works

cappuccino and spire: two unique maternal-effect loci required for both the anteroposterior and dorsoventral patterns of the Drosophila embryo.Preprint

Manseau, L. J., & Schüpbach, T. (1989) · Genes & Development · doi:10.1101/gad.3.9.1437 · Cited by 243 · see citing works

Courtship in S. cerevisiae: Both cell types choose mating partners by responding to the strongest pheromone signal

Jackson, C. L., & Hartwell, L. H. (1990) · Cell · doi:10.1016/0092-8674(90)90507-b · Cited by 208 · see citing works

Multiple functions of let-23, a Caenorhabditis elegans receptor tyrosine kinase gene required for vulval induction.

Aroian, R. V., & Sternberg, P. W. (1991) · Genetics · doi:10.1093/genetics/128.2.251 · Cited by 173 · see citing works

Studies concerning the temporal and genetic control of cell polarity in Saccharomyces cerevisiae.

Snyder, M., Gehrung, S., & Page, B. D. (1991) · The Journal of Cell Biology · doi:10.1083/jcb.114.3.515 · Cited by 137 · see citing works

S. cerevisiae α pheromone receptors activate a novel signal transduction pathway for mating partner discrimination

Jackson, C. L., Konopka, J. B., & Hartwell, L. H. (1991) · Cell · doi:10.1016/0092-8674(91)90190-a · Cited by 126 · see citing works

lin-17 mutations of Caenorhabditis elegans disrupt certain asymmetric cell divisions

Sternberg, P. W., & Horvitz, H. R. (1988) · Developmental Biology · doi:10.1016/0012-1606(88)90414-9 · Cited by 124 · see citing works

Gonadal cell lineages of the nematode Panagrellus redivivus and implications for evolution by the modification of cell lineage

Sternberg, P. W., & Horvitz, H. R. (1981) · Developmental Biology · doi:10.1016/0012-1606(81)90226-8 · Cited by 107 · see citing works

Postembryonic nongonadal cell lineages of the nematode Panagrellus redivivus: Description and comparison with those of Caenorhabditis elegans

Sternberg, P. W., & Horvitz, H. R. (1982) · Developmental Biology · doi:10.1016/0012-1606(82)90251-2 · Cited by 100 · see citing works

RSR1, a ras -Like Gene Homologous to Krev-1 ( smg21A/rap1A ): Role in the Development of Cell Polarity and Interactions with the Ras Pathway in Saccharomyces cerevisiae

Ruggieri, R., Bender, A., Matsui, Y., Powers, S., Takai, Y., Pringle, J. R., & Matsumoto, K. (1992) · Molecular and Cellular Biology · doi:10.1128/mcb.12.2.758-766.1992 · Cited by 98 · see citing works

A SECOND INFORMATIONAL SUPPRESSOR, SUP-7 X, IN CAENORHABDITIS ELEGANS

Waterston, R. (1981) · Genetics · doi:10.1093/genetics/97.2.307 · Cited by 81 · see citing works

Genetic analysis of a large autosomal region inCaenorhabditis elegansby the use of a free duplication

Howell, A. M., Gilmour, S. G., Mancebo, R., & Rose, A. M. (1987) · Genetics Research · doi:10.1017/s0016672300027099 · Cited by 46 · see citing works

Genes That Affect Cell Fates during the Development of Caenorhabditis elegansPreprint

Fixsen, W. D., Sternberg, P. W., Ellis, H., & Horvitz, R. (1985) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.1985.050.01.014 · Cited by 46 · see citing works

Chromosome I duplications in Caenorhabditis elegans.

McKim, K. S., & Rose, A. M. (1990) · Genetics · doi:10.1093/genetics/124.1.115 · Cited by 42 · see citing works

Essential genes in the hDf6 region of chromosome I in Caenorhabditis elegans.

Howell, A. M., & Rose, A. M. (1990) · Genetics · doi:10.1093/genetics/126.3.583 · Cited by 38 · see citing works

The mab-9 gene controls the fate of B, the major male-specific blast cell in the tail region of Caenorhabditis elegans.Preprint

Chisholm, A. D., & Hodgkin, J. (1989) · Genes & Development · doi:10.1101/gad.3.9.1413 · Cited by 35 · see citing works

APPENDIX 4 GeneticsPreprint

Hodgkin, J., Edgley, M. L., Riddle, D. L., & Albertson, D. G. (1988) · Cold Spring Harbor Monograph Archive · doi:10.1101/087969307.17.491 · Cited by 24 · see citing works

A new member of the frizzled family from Drosophila functions as a Wingless receptor

Bhanot, P., van den Brink, M. R. M., Samos, C. H., Hsieh, J.-C., Wang, Y., Macke, J. P., Andrew, D. J., Nathans, J., & Nusse, R. (1996) · Nature · doi:10.1038/382225a0 · Cited by 1,504 · see citing works

Wnt Signaling and the Polarity of the Primary Body Axis

Petersen, C. P., & Reddien, P. W. (2009) · Cell · doi:10.1016/j.cell.2009.11.035 · Cited by 544 · see citing works

Wnt Signaling Polarizes an Early C. elegans Blastomere to Distinguish Endoderm from Mesoderm

Thorpe, C. J., Schlesinger, A., Carter, J. C., & Bowerman, B. A. (1997) · Cell · doi:10.1016/s0092-8674(00)80530-9 · Cited by 514 · see citing works

Identification and behavior of epithelial stem cells in the Drosophila ovary

Margolis, J. S., & Spradling, A. C. (1995) · Development · doi:10.1242/dev.121.11.3797 · Cited by 448 · see citing works

A Role for the Wnt Gene Family in Hematopoiesis: Expansion of Multilineage Progenitor Cells

Austin, T. W., Solar, G. P., Ziegler, F. C., Liem, L. M., & Matthews, W. (1997) · Blood · doi:10.1182/blood.v89.10.3624 · Cited by 358 · see citing works

A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion

Harterink, M., Port, F., Lorenowicz, M. J., McGough, I. J., Silhankova, M., Betist, M. C., van Weering, J. R. T., van Heesbeen, R. G. H. P., Middelkoop, T. C., Basler, K., et al. (2011) · Nature Cell Biology · doi:10.1038/ncb2281 · Cited by 337 · see citing works

Mutations affecting the chemosensory neurons of Caenorhabditis elegans.

Starich, T. A., Herman, R. K., Kari, C. K., Yeh, W. H., Schackwitz, W., Schuyler, M. W., Collet, J., Thomas, J. H., & Riddle, D. L. (1995) · Genetics · doi:10.1093/genetics/139.1.171 · Cited by 262 · see citing works

Wnt Signaling Requires Retromer-Dependent Recycling of MIG-14/Wntless in Wnt-Producing Cells

Yang, P., Lorenowicz, M. J., Macůrková, M., Coudreuse, D. Y. M., Betist, M. C., & Korswagen, H. C. (2007) · Developmental Cell · doi:10.1016/j.devcel.2007.12.004 · Cited by 257 · see citing works

The β-catenin homolog BAR-1 and LET-60 Ras coordinately regulate the Hox gene lin-39 during Caenorhabditis elegans vulval development

Eisenmann, D. M., Maloof, J., Simske, J. S., Kenyon, C. J., & Kim, S. K. (1998) · Development · doi:10.1242/dev.125.18.3667 · Cited by 256 · see citing works

Wnt Gradient Formation Requires Retromer Function in Wnt-Producing Cells

Coudreuse, D. Y. M., Roël, G., Betist, M. C., Destrée, O., & Korswagen, H. C. (2006) · Science · doi:10.1126/science.1124856 · Cited by 252 · see citing works

A wound-induced Wnt expression program controls planarian regeneration polarity

Petersen, C. P., & Reddien, P. W. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0906823106 · Cited by 251 · see citing works

WRM-1 Activates the LIT-1 Protein Kinase to Transduce Anterior/Posterior Polarity Signals in C. elegans

Rocheleau, C. E., Yasuda, J., Shin, T. H., Lin, R., Sawa, H., Okano, H., Priess, J. R., Davis, R. J., & Mello, C. C. (1999) · Cell · doi:10.1016/s0092-8674(00)80784-9 · Cited by 276 · see citing works

Wnt signaling establishes anteroposterior neuronal polarity and requires retromer in C. elegans

Prasad, B. C., & Clark, S. G. (2006) · Development · doi:10.1242/dev.02357 · Cited by 219 · see citing works

Regulation of Lymphoid Enhancer Factor 1/T-Cell Factor by Mitogen-Activated Protein Kinase-Related Nemo-Like Kinase-Dependent Phosphorylation in Wnt/β-Catenin Signaling

Ishitani, T., Ninomiya-Tsuji, J., & Matsumoto, K. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.4.1379-1389.2003 · Cited by 212 · see citing works

The Caenorhabditis elegans gene lin-17, which is required for certain asymmetric cell divisions, encodes a putative seven-transmembrane protein similar to the Drosophila frizzled protein.Preprint

Sawa, H., Lobel, L. I., & Horvitz, H. R. (1996) · Genes & Development · doi:10.1101/gad.10.17.2189 · Cited by 209 · see citing works

Genetics of RAS signaling in C. elegans

Sternberg, P. W., & Han, M. (1998) · Trends in Genetics · doi:10.1016/s0168-9525(98)01592-3 · Cited by 205 · see citing works

Wnt Signals and Frizzled Activity Orient Anterior-Posterior Axon Outgrowth in C. elegans

Hilliard, M. A., & Bargmann, C. I. (2006) · Developmental Cell · doi:10.1016/j.devcel.2006.01.013 · Cited by 199 · see citing works

C. elegans LIN-18 Is a Ryk Ortholog and Functions in Parallel to LIN-17/Frizzled in Wnt Signaling

Inoue, T., Oz, H. S., Wiland, D., Gharib, S., Deshpande, R., Hill, R. J., Katz, W. S., & Sternberg, P. W. (2004) · Cell · doi:10.1016/j.cell.2004.09.001 · Cited by 183 · see citing works

The C. elegans gene lin-44, which controls the polarity of certain asymmetric cell divisions, encodes a Wnt protein and acts cell nonautonomously

Herman, M. A., Vassilieva, L. L., Horvitz, H. R., Shaw, J. E., & Herman, R. K. (1995) · Cell · doi:10.1016/0092-8674(95)90238-4 · Cited by 199 · see citing works

Wnt Signals Can Function as Positional Cues in Establishing Cell Polarity

Goldstein, B., Takeshita, H., Mizumoto, K., & Sawa, H. (2006) · Developmental Cell · doi:10.1016/j.devcel.2005.12.016 · Cited by 163 · see citing works

Molecular pathways that influence human tau-induced pathology in Caenorhabditis elegans

Kraemer, B. C., Burgess, J. K., Chen, J. H., Thomas, J. H., & Schellenberg, G. D. (2006) · Human Molecular Genetics · doi:10.1093/hmg/ddl067 · Cited by 150 · see citing works

Canonical and non‐canonical Wnt signaling pathways in Caenorhabditis elegans : variations on a common signaling theme

Korswagen, H. C. (2002) · BioEssays · doi:10.1002/bies.10145 · Cited by 133 · see citing works

Reciprocal asymmetry of SYS-1/β-catenin and POP-1/TCF controls asymmetric divisions in Caenorhabditis elegans

Phillips, B. T., Kidd, A. R., King, R., Hardin, J. D., & Kimble, J. E. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0611507104 · Cited by 132 · see citing works

Protruding Vulva Mutants Identify Novel Loci and Wnt Signaling Factors That Function During Caenorhabditis elegans Vulva Development

Eisenmann, D. M., & Kim, S. K. (2000) · Genetics · doi:10.1093/genetics/156.3.1097 · Cited by 119 · see citing works

The Caenorhabditis elegans genes egl-27 and egr-1 are similar to MTA1, a member of a chromatin regulatory complex, and are redundantly required for embryonic patterning

Solari, F., Bateman, A. G., & Ahringer, J. (1999) · Development · doi:10.1242/dev.126.11.2483 · Cited by 112 · see citing works

POP-1 controls axis formation during early gonadogenesis in<i>C. elegans</i>

Siegfried, K. R., & Kimble, J. (2002) · Development · doi:10.1242/dev.129.2.443 · Cited by 136 · see citing works

Neuroblast migration along the anteroposterior axis of C. elegans is controlled by opposing gradients of Wnts and a secreted Frizzled-related protein

Harterink, M., Kim, D. H., Middelkoop, T. C., Doan, T. D., van Oudenaarden, A., & Korswagen, H. C. (2011) · Development · doi:10.1242/dev.064733 · Cited by 109 · see citing works

The sys-1 and sys-3 Genes Cooperate With Wnt Signaling to Establish the Proximal-Distal Axis of the Caenorhabditis elegans Gonad

Siegfried, K. R., Kidd, A. R., Chesney, M. A., & Kimble, J. E. (2004) · Genetics · doi:10.1534/genetics.166.1.171 · Cited by 107 · see citing works

The putative Wnt receptor Xenopus frizzled-7 functions upstream of β-catenin in vertebrate dorsoventral mesoderm patterning

Sumanas, S., Strege, P. R., Heasman, J., & Ekker, S. C. (2000) · Development · doi:10.1242/dev.127.9.1981 · Cited by 105 · see citing works

Wnt Signaling Regulates Acetylcholine Receptor Translocation and Synaptic Plasticity in the Adult Nervous System

Jensen, M., Hoerndli, F. J., Brockie, P. J., Wang, R., Johnson, E., Maxfield, D., Francis, M. M., Madsen, D. M., & Maricq, A. V. (2012) · Cell · doi:10.1016/j.cell.2011.12.038 · Cited by 103 · see citing works

Cortical β-Catenin and APC Regulate Asymmetric Nuclear β-Catenin Localization during Asymmetric Cell Division in C. elegans

Mizumoto, K., & Sawa, H. (2007) · Developmental Cell · doi:10.1016/j.devcel.2007.01.004 · Cited by 101 · see citing works

<i>C. elegans</i> POP-1/TCF functions in a canonical Wnt pathway that controls cell migration and in a noncanonical Wnt pathway that controls cell polarity

Herman, M. A. (2001) · Development · doi:10.1242/dev.128.4.581 · Cited by 118 · see citing works

Interactions of EGF, Wnt and HOM-C genes specify the P12 neuroectoblast fate in C. elegans

Jiang, L. I., & Sternberg, P. W. (1998) · Development · doi:10.1242/dev.125.12.2337 · Cited by 98 · see citing works

Components of the SWI/SNF Complex Are Required for Asymmetric Cell Division in C. elegans

Sawa, H., Kouike, H., & Okano, H. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)00060-5 · Cited by 95 · see citing works

The epidermal growth factor system in caenorhabditis elegans

Moghal, N. (2003) · Experimental Cell Research · doi:10.1016/s0014-4827(02)00097-6 · Cited by 95 · see citing works

Components of the transcriptional Mediator complex are required for asymmetric cell division inC. elegans

Yoda, A., Kouike, H., Okano, H., & Sawa, H. (2005) · Development · doi:10.1242/dev.01776 · Cited by 87 · see citing works

Wnt signalling in the development of axon, dendrites and synapses

He, C.-W., Liao, C., & Pan, C. (2018) · Open Biology · doi:10.1098/rsob.180116 · Cited by 82 · see citing works

Lineage-specific regulators couple cell lineage asymmetry to the transcription of the Caenorhabditis elegans POU gene unc-86 during neurogenesis.Preprint

Baumeister, R., Liu, Y., & Ruvkun, G. (1996) · Genes & Development · doi:10.1101/gad.10.11.1395 · Cited by 85 · see citing works

Complex Network of Wnt Signaling Regulates Neuronal Migrations DuringCaenorhabditis elegansDevelopment

Zinovyeva, A., Yamamoto, Y., Sawa, H., & Forrester, W. C. (2008) · Genetics · doi:10.1534/genetics.108.090290 · Cited by 84 · see citing works

Morphogenesis of theCaenorhabditis elegansMale Tail Tip

Nguyen, C. Q., Hall, D. H., Yang, Y., & Fitch, D. H. A. (1999) · Developmental Biology · doi:10.1006/dbio.1998.9173 · Cited by 75 · see citing works

Asymmetric cell division: from A to ZPreprint

Hawkins, N., & Garriga, G. (1998) · Genes & Development · doi:10.1101/gad.12.23.3625 · Cited by 71 · see citing works

EGL-27 is similar to a metastasis-associated factor and controls cell polarity and cell migration in C. elegans

Herman, M. A., Ch'ng, Q.-L., Hettenbach, S. M., Ratliff, T. M., Kenyon, C. J., & Herman, R. K. (1999) · Development · doi:10.1242/dev.126.5.1055 · Cited by 70 · see citing works

From “the Worm” to “the Worms” and Back Again: The Evolutionary Developmental Biology of Nematodes

Haag, E. S., Fitch, D. H. A., & Delattre, M. (2018) · Genetics · doi:10.1534/genetics.118.300243 · Cited by 68 · see citing works

The C. elegans Frizzled CFZ-2 is required for cell migration and interacts with multiple Wnt signaling pathways

Zinovyeva, A., & Forrester, W. C. (2005) · Developmental Biology · doi:10.1016/j.ydbio.2005.07.014 · Cited by 68 · see citing works

Asymmetric distribution of the C. elegans HAM-1 protein in neuroblasts enables daughter cells to adopt distinct fates

Guenther, C. A., & Garriga, G. (1996) · Development · doi:10.1242/dev.122.11.3509 · Cited by 64 · see citing works

Wnt signaling controls the stem cell-like asymmetric division of the epithelial seam cells during C. elegans larval development

Gleason, J. E., & Eisenmann, D. M. (2010) · Developmental Biology · doi:10.1016/j.ydbio.2010.09.005 · Cited by 60 · see citing works

A novel noncanonical Wnt pathway is involved in the regulation of the asymmetric B cell division in C. elegans

Wu, M., & Herman, M. A. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2005.12.024 · Cited by 59 · see citing works

Evolution of Male Tail Development in Rhabditid Nematodes Related to Caenorhabditis Elegans

Fitch, D. H. A. (1997) · Systematic Biology · doi:10.1093/sysbio/46.1.145 · Cited by 56 · see citing works

Multiple Wnts Redundantly Control Polarity Orientation in Caenorhabditis elegans Epithelial Stem Cells

Yamamoto, Y., Takeshita, H., & Sawa, H. (2011) · PLoS Genetics · doi:10.1371/journal.pgen.1002308 · Cited by 55 · see citing works

Wnt signal from multiple tissues and lin-3 /EGF signal from the gonad maintain vulval precursor cell competence in Caenorhabditis elegans

Myers, T. R., & Greenwald, I. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0709989104 · Cited by 53 · see citing works

Multiple levels of regulation specify the polarity of an asymmetric cell division in C. elegans

Whangbo, J., Harris, J. M., & Kenyon, C. J. (2000) · Development · doi:10.1242/dev.127.21.4587 · Cited by 51 · see citing works

TLP-1 is an asymmetric cell fate determinant that responds to Wnt signals and controls male tail tip morphogenesis inC. elegans

Zhao, X. J., Yang, Y. L., Fitch, D. H. A., & Herman, M. A. (2002) · Development · doi:10.1242/dev.129.6.1497 · Cited by 50 · see citing works

C. elegansGATA factors EGL-18 and ELT-6 function downstream of Wnt signaling to maintain the progenitor fate during larval asymmetric divisions of the seam cells

Gorrepati, L., Thompson, K. W., & Eisenmann, D. M. (2013) · Development · doi:10.1242/dev.091124 · Cited by 49 · see citing works

Tissue-Specific Regulation of the LIM Homeobox Gene lin-11 during Development of the Caenorhabditis elegans Egg-Laying System

Gupta, B. P., & Sternberg, P. W. (2002) · Developmental Biology · doi:10.1006/dbio.2002.0688 · Cited by 48 · see citing works

lin-35/Rb Cooperates With the SWI/SNF Complex to Control Caenorhabditis elegans Larval Development

Cui, M., Fay, D. S., & Han, M. (2004) · Genetics · doi:10.1534/genetics.103.024554 · Cited by 48 · see citing works

Evidence for a frizzled-mediated wnt pathway required for zebrafish dorsal mesoderm formation

Nasevicius, A., Hyatt, T. M., Kim, H., Guttman, J., Walsh, E., Sumanas, S., Wang, Y., & Ekker, S. C. (1998) · Development · doi:10.1242/dev.125.21.4283 · Cited by 46 · see citing works

A β-Catenin-Dependent Wnt Pathway Mediates Anteroposterior Axon Guidance in C. elegans Motor Neurons

Maro, G. S., Klassen, M. P., & Shen, K. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004690 · Cited by 45 · see citing works

The Tumor Suppressor BCL7B Functions in the Wnt Signaling Pathway

Uehara, T., Kage-Nakadai, E., Yoshina, S., Imae, R., & Mitani, S. (2015) · PLoS Genetics · doi:10.1371/journal.pgen.1004921 · Cited by 40 · see citing works

LIN-44/Wnt Directs Dendrite Outgrowth through LIN-17/Frizzled in C. elegans Neurons

Kirszenblat, L., Pattabiraman, D., & Hilliard, M. A. (2011) · PLoS Biology · doi:10.1371/journal.pbio.1001157 · Cited by 41 · see citing works

MOM-5 Frizzled regulates the distribution of DSH-2 to control C. elegans asymmetric neuroblast divisions

Hawkins, N., Ellis, G. C., Bowerman, B. A., & Garriga, G. (2005) · Developmental Biology · doi:10.1016/j.ydbio.2005.05.024 · Cited by 40 · see citing works

REF-1, a protein with two bHLH domains, alters the pattern of cell fusion inC. elegansby regulating Hox protein activity

Alper, S., & Kenyon, C. J. (2001) · Development · doi:10.1242/dev.128.10.1793 · Cited by 40 · see citing works

lin-17/Frizzled and lin-18 regulate POP-1/TCF-1 localization and cell type specification during C. elegans vulval development

Deshpande, R., Inoue, T., Priess, J. R., & Hill, R. J. (2004) · Developmental Biology · doi:10.1016/j.ydbio.2004.10.020 · Cited by 38 · see citing works

Control of cell polarity by noncanonical Wnt signaling in C. elegans

Herman, M. A. (2002) · Seminars in Cell and Developmental Biology · doi:10.1016/s1084-9521(02)00051-4 · Cited by 36 · see citing works

lin-35/Rb and xnp-1/ATR-X function redundantly to control somatic gonad development in C. elegans

Bender, A. M., Wells, O., & Fay, D. S. (2004) · Developmental Biology · doi:10.1016/j.ydbio.2004.06.009 · Cited by 36 · see citing works

Distinct DNA Binding Sites Contribute to the TCF Transcriptional Switch in C. elegans and Drosophila

Bhambhani, C., Ravindranath, A. J., Mentink, R. A., Chang, M. V., Betist, M. C., Yang, Y. X., Koushika, S. P., Korswagen, H. C., & Cadigan, K. M. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004133 · Cited by 35 · see citing works

The role of C. elegans Ena/VASP homolog UNC-34 in neuronal polarity and motility

Fleming, T. C., Chien, S.-C., Vanderzalm, P. J., Dell, M., Gavin, M. K., Forrester, W. C., & Garriga, G. (2010) · Developmental Biology · doi:10.1016/j.ydbio.2010.04.025 · Cited by 35 · see citing works

Chapter 1 Somatic Sexual Differentiation in Caenorhabditis elegans

Wolff, J. R., & Zarkower, D. A. (2008) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/s0070-2153(08)00401-8 · Cited by 35 · see citing works

The C. elegans CBFβ homolog, BRO-1, regulates the proliferation, differentiation and specification of the stem cell-like seam cell lineages

Xia, D., Zhang, Y., Huang, X., Sun, Y., & Zhang, H. (2007) · Developmental Biology · doi:10.1016/j.ydbio.2007.07.020 · Cited by 34 · see citing works

The Flightless I Homolog, fli-1, Regulates Anterior/Posterior Polarity, Asymmetric Cell Division and Ovulation During Caenorhabditis elegans Development

Deng, H., Xia, D., Fang, B., & Zhang, H. (2007) · Genetics · doi:10.1534/genetics.107.078964 · Cited by 34 · see citing works

Asymmetric localizations of LIN-17/Fz and MIG-5/Dsh are involved in the asymmetric B cell division in C. elegans

Wu, M., & Herman, M. A. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2006.12.002 · Cited by 33 · see citing works

The evolution of cell lineage in nematodes

Sommer, R. J., Carta, L. K., & Sternberg, P. W. (1994) · Development · doi:10.1242/dev.1994.supplement.85 · Cited by 33 · see citing works

Noncanonical WNT signaling pathways in C. Elegans converge on POP-1/TCF and control cell polarity

Michael, A. H. (2004) · Frontiers in bioscience · doi:10.2741/1306 · Cited by 33 · see citing works

eor-1 and eor-2 are required for cell-specific apoptotic death in C. elegans

Hoeppner, D. J., Spector, M. S., Ratliff, T. M., Kinchen, J. M., Granat, S., Lin, S., Bhusri, S. S., Conradt, B., Herman, M. A., & Hengartner, M. O. (2004) · Developmental Biology · doi:10.1016/j.ydbio.2004.06.022 · Cited by 32 · see citing works

The C. elegans RUNX transcription factor RNT-1/MAB-2 is required for asymmetrical cell division of the T blast cell

Kagoshima, H., Sawa, H., Mitani, S., Bürglin, T. R., Shigesada, K., & Kohara, Y. (2005) · Developmental Biology · doi:10.1016/j.ydbio.2005.08.034 · Cited by 31 · see citing works

The development of sexual dimorphism: studies of the Caenorhabditis elegans male

Emmons, S. W. (2014) · Wiley Interdisciplinary Reviews Developmental Biology · doi:10.1002/wdev.136 · Cited by 30 · see citing works

Cyclin D Regulation of a Sexually Dimorphic Asymmetric Cell Division

Tilmann, C., & Kimble, J. E. (2005) · Developmental Cell · doi:10.1016/j.devcel.2005.09.004 · Cited by 28 · see citing works

Hermaphrodite cell-fate specification

Herman, M. A. (2006) · WormBook · doi:10.1895/wormbook.1.39.1 · Cited by 27 · see citing works

An HMG1-like protein facilitates Wnt signaling in Caenorhabditis elegansPreprint

Jiang, L. I., & Sternberg, P. W. (1999) · Genes & Development · doi:10.1101/gad.13.7.877 · Cited by 27 · see citing works

Involvement of Wnt Signaling Pathways in the Metamorphosis of the Bryozoan Bugula neritina

Wong, Y. H., Wang, H., Ravasi, T., & Qian, P. (2012) · PLoS ONE · doi:10.1371/journal.pone.0033323 · Cited by 26 · see citing works

Transcriptional control of non-apoptotic developmental cell death in C. elegans

Malin, J. A., Kinet, M., Abraham, M. C., Blum, E. S., & Shaham, S. (2016) · Cell Death and Differentiation · doi:10.1038/cdd.2016.77 · Cited by 21 · see citing works

The LIN-29 Transcription Factor Is Required for Proper Morphogenesis of theCaenorhabditis elegansMale Tail

Euling, S. Y., Bettinger, J. C., & Rougvie, A. E. (1999) · Developmental Biology · doi:10.1006/dbio.1998.9063 · Cited by 21 · see citing works

Development and Evolution of a Variable Left–Right Asymmetry in Nematodes: The Handedness of P11/P12 Migration

Delattre, M., & Félix, M. (2001) · Developmental Biology · doi:10.1006/dbio.2001.0175 · Cited by 21 · see citing works

Cell Identification and Cell Lineage Analysis

Giurumescu, C. A., & Chisholm, A. D. (2011) · Methods in cell biology · doi:10.1016/b978-0-12-544172-8.00012-8 · Cited by 18 · see citing works

Identification of Wnt Pathway Target Genes Regulating the Division and Differentiation of Larval Seam Cells and Vulval Precursor Cells inCaenorhabditis elegans

Gorrepati, L., Krause, M., Chen, W., Brodigan, T. M., Correa-Méndez, M., & Eisenmann, D. M. (2015) · G3 Genes Genomes Genetics · doi:10.1534/g3.115.017715 · Cited by 17 · see citing works

Wnt and EGF pathways act together to induce C. elegans male hook development

Yu, H. M., Seah, A., Herman, M. A., Ferguson, E. L., Horvitz, H. R., & Sternberg, P. W. (2008) · Developmental Biology · doi:10.1016/j.ydbio.2008.12.023 · Cited by 17 · see citing works

The nuclear receptor NHR-25 cooperates with the Wnt/β-catenin asymmetry pathway to control differentiation of the T seam cell inC. elegans

Hajdůšková, M., Jindra, M., Herman, M. A., & Asahina, M. (2009) · Journal of Cell Science · doi:10.1242/jcs.052373 · Cited by 17 · see citing works

Anchor cell signaling and vulval precursor cell positioning establish a reproducible spatial context during C. elegans vulval induction

Grimbert, S., Tietze, K., Barkoulas, M., Sternberg, P. W., Félix, M., & Braendle, C. (2016) · Developmental Biology · doi:10.1016/j.ydbio.2016.05.036 · Cited by 16 · see citing works

Cell Fate Determination in Caenorhabditis elegans Ray Development

Emmons, S. W. (1999) · Elsevier eBooks · doi:10.1016/b978-012505255-9/50010-9 · Cited by 16 · see citing works

The Wnt/β-Catenin Asymmetry Pathway Patterns theAtonalOrthologlin-32to Diversify Cell Fate in aCaenorhabditis elegansSensory Lineage

Miller, R. M., & Portman, D. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.6504-10.2011 · Cited by 15 · see citing works

Mechanisms of lineage specification in Caenorhabditis elegans

Liu, J., & Murray, J. I. (2023) · Genetics · doi:10.1093/genetics/iyad174 · Cited by 14 · see citing works

A High-Throughput Small Molecule Screen for C. elegans Linker Cell Death Inhibitors

Schwendeman, A. R., & Shaham, S. (2016) · PLoS ONE · doi:10.1371/journal.pone.0164595 · Cited by 14 · see citing works

Accelerating Gene Discovery by Phenotyping Whole-Genome Sequenced Multi-mutation Strains and Using the Sequence Kernel Association Test (SKAT)

Timbers, T., Garland, S. J., Mohan, S., Flibotte, S., Edgley, M. L., Muncaster, Q., Au, V., Li-Leger, E., Rosell, F. I., Cai, J., et al. (2016) · PLoS Genetics · doi:10.1371/journal.pgen.1006235 · Cited by 13 · see citing works

CWN-1 functions with DSH-2 to regulate C. elegans asymmetric neuroblast division in a β-catenin independent Wnt pathway

Hingwing, K., Lee, S., Nykilchuk, L., Walston, T., Hardin, J. D., & Hawkins, N. (2009) · Developmental Biology · doi:10.1016/j.ydbio.2009.01.025 · Cited by 11 · see citing works

Wnt Signaling in C. elegans

Herman, M. A. (2003) · Cited by 11 · see citing works

Wnts Promote Synaptic Assembly Through T-Cell Specific Transcription Factors in Caenorhabditis elegans

Shi, Y., Li, Q., & Shao, Z. (2018) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2018.00194 · Cited by 10 · see citing works

HOM-C genes, Wnt signaling and axial patterning in the C. elegans posterior ventral epidermis

Li, X., Kulkarni, R., Hill, R. J., & Chamberlin, H. (2009) · Developmental Biology · doi:10.1016/j.ydbio.2009.05.567 · Cited by 10 · see citing works

Cell polarity control by Wnt morphogens

Chen, C., & Pan, C. (2022) · Developmental Biology · doi:10.1016/j.ydbio.2022.04.007 · Cited by 9 · see citing works

Tcl-2 encodes a novel protein that acts synergistically with Wnt signaling pathways in C. elegans

Zhao, X. J., Sawa, H., & Herman, M. A. (2003) · Developmental Biology · doi:10.1016/s0012-1606(02)00128-8 · Cited by 9 · see citing works

Size Matters: How C. elegans Asymmetric Divisions Regulate Apoptosis

Teulière, J., & Garriga, G. (2017) · Results and problems in cell differentiation · doi:10.1007/978-3-319-53150-2_6 · Cited by 8 · see citing works

Getting signals crossed in C. elegans

Hanna-Rose, W., & Han, M. (2000) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(00)00122-2 · Cited by 8 · see citing works

Establishment of PAR Protein Polarity during Asymmetric Cell Divisions in Caenorhabditis Elegans

Trong, P. K. (2009)

Multiple Wnts Redundantly Control Polarity Orientation in Caenorhabditis elegans Epithelial Stem Cells

Yamamoto, Y., Takeshita, H., & Sawa, H. (2011) · PLoS Genetics · doi:10.1371/journal.pgen.1002308 · Cited by 55 · see citing works

Differential functions of multiple Wnts and receptors in cell polarity regulation in Caenorhabditis elegans

Sawa, H., Asakawa, M., & Negishi, T. (2026) · Genetics · doi:10.1093/genetics/iyag004 · Cited by 2 · see citing works

Cell Polarity in One-Cell C. elegans Embryos: Ensuring an Accurate and Precise Spatial Axis During Development

Mikl, M., & Cowan, C. R. (2015) · Springer eBooks · doi:10.1007/978-3-319-14466-5_1 · Cited by 1 · see citing works

Cell polarity and asymmetric cell division: the C. elegans early embryo

Noatynska, A., & Gotta, M. (2012) · Essays in Biochemistry · doi:10.1042/bse0530001 · Cited by 20 · see citing works