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Pax6-dependent regulation of adhesive patterning, R-cadherin expression and boundary formation in developing forebrain
Open accessAbstract
Mutations in the gene for the transcription factor, Pax6, induce marked developmental abnormalities in the CNS and the eye, but the cellular mechanisms that underlie the phenotype are unknown. We have examined the adhesive properties of cells from the developing forebrain in Small eye, the Pax6 mutant mouse. We have found that the seg-regation normally observed in aggregates of cortical and striatal cells in an in vitro assay is lost in Small eye. This correlates with an alteration of in vivo expression of the homophilic adhesion molecule, R-cadherin. Moreover, the boundary between cortical and striatal regions of the telencephalon is dramatically altered in Small eye: radial glial fascicles do not form at the border, and the normal expression of R-cadherin and tenascin-C at the border is lost. These data suggest a link between the transcription factor, Pax6, R-cadherin expression, cellular adhesion and boundary formation between developing forebrain regions.
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Citations
Cites
Gene regulation by steroid hormones
Beato, M. (1989) · Cell · doi:10.1016/0092-8674(89)90237-7 · Cited by 3,383
Growth of a rat neuroblastoma cell line in serum-free supplemented medium.
Bottenstein, J. E., & Sato, G. H. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.1.514 · Cited by 2,276
Hox genes in vertebrate development
Krumlauf, R. (1994) · Cell · doi:10.1016/0092-8674(94)90290-9 · Cited by 2,073
A protein related to extracellular matrix proteins deleted in the mouse mutant reeler
D'Arcangelo, G., G. Miao, G., Chen, S.-C., Scares, H. D., Morgan, J. I., & Curran, T. (1995) · Nature · doi:10.1038/374719a0 · Cited by 1,748
Erratum: Mouse Small eye results from mutation in a paired-like homebox-containing gene
Hill, R. E., Favor, J., Hogan, B. L. M., Ton, C. C. T., Saunders, G. F., Hanson, I. M., Prosser, J., Jordan, T., Hastie, N. D., & van Heyningen, V. (1992) · Nature · doi:10.1038/355750a0 · Cited by 1,270
Pax-6, a murine paired box gene, is expressed in the developing CNS
Walther, C., & Gruss, P. (1991) · Development · doi:10.1242/dev.113.4.1435 · Cited by 1,255
Self-citationMouse Small eye results from mutations in a paired-like homeobox-containing gene
Hill, R. E., Favor, J., Hogan, B. L. M., Ton, C. C. T., Saunders, G. F., Hanson, I. M., Prosser, J., Jordan, T., Hastie, N. D., & Heyningen, V. V. (1991) · Nature · doi:10.1038/354522a0 · Cited by 1,158
Patterning the Vertebrate Neuraxis
Lumsden, A., & Krumlauf, R. (1996) · Science · doi:10.1126/science.274.5290.1109 · Cited by 1,146
Ogawa, M., Miyata, T., Nakajimat, K., Yagyu, K., Seike, M., Ikenaka, K., Yamamoto, H., & Mikoshibat, K. (1995) · Neuron · doi:10.1016/0896-6273(95)90329-1 · Cited by 889
Nusse, R., & Varmus, H. E. (1992) · Cell · doi:10.1016/0092-8674(92)90630-u · Cited by 815
Puelles, L., & Rubenstein, J. L. R. (1993) · Trends in Neurosciences · doi:10.1016/0166-2236(93)90080-6 · Cited by 783
Glaser, T., Jepeal, L., Edwards, J. G., Young, S. R., Favor, J., & Maas, R. L. (1994) · Nature Genetics · doi:10.1038/ng0894-463 · Cited by 713
Simeone, A., Acampora, D., Mallamaci, A., Stornaiuolo, A., D'Apice, M. R., Nigro, V., & Boncinelli, E. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb05935.x · Cited by 617
Miller, M. W., & Nowakowski, R. S. (1988) · Brain Research · doi:10.1016/0006-8993(88)90055-8 · Cited by 610
Guidance of neurons migrating to the fetal monkey neocortex
Rakic, P. (1971) · Brain Research · doi:10.1016/0006-8993(71)90119-3 · Cited by 589
Roles of Pax-genes in developing and adult brain as suggested by expression patterns
Stoykova, A., & Gruss, P. (1994) · The Journal of Neuroscience · doi:10.1523/jneurosci.14-03-01395.1994 · Cited by 579
Self-citationBulfone, A., Puelles, L., Porteus, M., Frohman, M., Martin, G., & Rubenstein, J. (1993) · The Journal of Neuroscience · doi:10.1523/jneurosci.13-07-03155.1993 · Cited by 574
Simeone, A., Gulisano, M., Acampora, D., Stornaiuolo, A., Rambaldi, M., & Boncinelli, E. (1992) · The EMBO Journal · doi:10.1002/j.1460-2075.1992.tb05319.x · Cited by 473
POU-domain transcription factors: pou-er-ful developmental regulators.
Rosenfeld, M. G. (1991) · Genes & Development · doi:10.1101/gad.5.6.897 · Cited by 447
Bulfone, A., Smiga, S. M., Shimamura, K., Peterson, A., Puelles, L., & Rubenstein, J. L. R. (1995) · Neuron · doi:10.1016/0896-6273(95)90065-9 · Cited by 425
Misson, J.-P., Edwards, M. A., Yamamoto, M., & Caviness, V. S. (1988) · Developmental Brain Research · doi:10.1016/0165-3806(88)90121-6 · Cited by 422
Dynamic expression of the murine Achaete-Scute homologue Mash-1 in the developing nervous system
Guillemot, F., & Joyner, A. L. (1993) · Mechanisms of Development · doi:10.1016/0925-4773(93)90006-j · Cited by 413
Dynamics of Cell Migration from the Lateral Ganglionic Eminence in the Rat
De Carlos, J. A., López-Mascaraque, L., & Valverde, F. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-19-06146.1996 · Cited by 403
Altered segmental identity and abnormal migration of motor neurons in mice lacking Hoxb-1
Studer, M., Lumsden, A., Ariza-McNaughton, L., Bradley, A., & Krumlauf, R. (1996) · Nature · doi:10.1038/384630a0 · Cited by 400
Forebrain patterning defects in Small eye mutant mice
Stoykova, A., Fritsch, R., Walther, C., & Gruss, P. (1996) · Development · doi:10.1242/dev.122.11.3453 · Cited by 378
Self-citationProx 1, a prospero-related homeobox gene expressed during mouse development
OLIVER, G., SOSAPINEDA, B., GEISENDORF, S., SPANA, E., DOE, C., & GRUSS, P. (1993) · Mechanisms of Development · doi:10.1016/0925-4773(93)90012-m · Cited by 369
Self-citationEmx1 and Emx2 functions in development of dorsal telencephalon
Yoshida, M., Suda, Y., Matsuo, I., Miyamoto, N., Takeda, N., Kuratani, S., & Aizawa, S. (1997) · Development · doi:10.1242/dev.124.1.101 · Cited by 364
Atlas of prenatal rat brain development
Altman, J., Bayer, S. A., & Gedney, C. (1994) · Cited by 360
Atlas Of The Developing Rat Brain
Paxinos, G., & Fritchle, A. L. R. (1991) · Medical Entomology and Zoology · Cited by 342
Matsuo, T., Osumi-Yamashita, N., Noji, S., Ohuchi, H., Koyama, E., Myokai, F., Matsuo, N., Taniguchi, S., Doi, H., Iseki, S., et al. (1993) · Nature Genetics · doi:10.1038/ng0493-299 · Cited by 316
Baird, A. (1994) · Current Opinion in Neurobiology · doi:10.1016/0959-4388(94)90035-3 · Cited by 297
Atlas of prenatal rat brain development
Puelles, L. (1996) · Trends in Neurosciences · doi:10.1016/s0166-2236(96)80042-7 · Cited by 289
Epilepsy and brain abnormalities in mice lacking the Otx1 gene
Acampora, D., Mazan, S., Avantaggiato, V., Barone, P., Tuorto, F., Lallemand, Y., Brûlet, P., & Simeone, A. (1996) · Nature Genetics · doi:10.1038/ng1096-218 · Cited by 281
A mouse gene related to Distal-less shows a restricted expression in the developing forebrain
Price, M., Lemaistre, M., Pischetola, M., Di Lauro, R., & Duboule, D. (1991) · Nature · doi:10.1038/351748a0 · Cited by 274
Dispersion of neural progenitors within the germinal zones of the forebrain
Fishell, G., Mason, C. A., & Hatten, M. E. (1993) · Nature · doi:10.1038/362636a0 · Cited by 269
Pax-6 functions in boundary formation and axon guidance in the embryonic mouse forebrain
Mastick, G. S., Davis, N. M., Andrews, G. L., & Easter, S. S. (1997) · Development · doi:10.1242/dev.124.10.1985 · Cited by 268
Redies, C., & Takeichi, M. (1996) · Developmental Biology · doi:10.1006/dbio.1996.0315 · Cited by 250
Edwards, M. A., Yamamoto, M., & caviness, V. S. (1990) · Neuroscience · doi:10.1016/0306-4522(90)90356-9 · Cited by 249
Dentate gyrus formation requires Emx2
Pellegrini, M., Mansouri, A., Simeone, A., Boncinelli, E., & Gruss, P. (1996) · Development · doi:10.1242/dev.122.12.3893 · Cited by 242
Self-citationSchmahl, W., Knoedlseder, M., Favor, J., & Davidson, D. (1993) · Acta Neuropathologica · doi:10.1007/bf00334879 · Cited by 206
Chazaud, C., Oulad-Abdelghani, M., Bouillet, P., Décimo, D., Chambon, P., & Dollé, P. (1996) · Mechanisms of Development · doi:10.1016/0925-4773(95)00463-7 · Cited by 184
Shimamura, K., Hirano, S., McMahon, A. P., & Takeichi, M. (1994) · Development · doi:10.1242/dev.120.8.2225 · Cited by 176
Matsunami, H., & Takeichi, M. (1995) · Developmental Biology · doi:10.1006/dbio.1995.8029 · Cited by 153
1 Homeobox Gene Expression during Development of the Vertebrate Brain
Rubenstein, J. L. R., & Puelles, L. (1994) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/s0070-2153(08)60546-3 · Cited by 132
Development of the endopiriform nucleus and the claustrum in the rat brain
Bayer, S. A., & Altman, J. (1991) · Neuroscience · doi:10.1016/0306-4522(91)90236-h · Cited by 129
Gläser, T., Jepeal, L. I., Edwards, J. G., Young, S. R., Favor, J., & Maas, R. L. (1994) · Nature Genetics · Cited by 125
Smart, I. H. M., & Sturrock, R. R. (1979) · Elsevier eBooks · doi:10.1016/b978-0-08-023174-7.50012-6 · Cited by 124
Expression of N‐cadherin mRNA during development of the mouse brain
Redies, C., & Takeichi, M. (1993) · Developmental Dynamics · doi:10.1002/aja.1001970104 · Cited by 108
Tremblay, P. J., & Gruß, P. (1994) · Pharmacology & Therapeutics · doi:10.1016/0163-7258(94)90063-9 · Cited by 103
Local and transient expression of E-cadherin involved in mouse embryonic brain morphogenesis
Shimamura, K., & Takeichi, M. (1992) · Development · doi:10.1242/dev.116.4.1011 · Cited by 101
Tenascin‐C Synthesis and Influence on Axonal Growth During Rat Cortical Development
Götz, M., Bolz, J., Joester, A., & Faissner, A. (1997) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1997.tb01627.x · Cited by 94
Self-citationFormation and preservation of cortical layers in slice cultures
Götz, M., & Bolz, J. (1992) · Journal of Neurobiology · doi:10.1002/neu.480230702 · Cited by 91
Self-citationSelective Adhesion of Cells from Different Telencephalic Regions
Götz, M., Wizenmann, A., Reinhardt, S., Lumsden, A., & Price, J. (1996) · Neuron · doi:10.1016/s0896-6273(00)80074-4 · Cited by 90
Self-citationNeurogenesis in the rat primary olfactory cortex
Bayer, S. A. (1986) · International Journal of Developmental Neuroscience · doi:10.1016/0736-5748(86)90063-8 · Cited by 79
Development of Dickie's small eye, a mutation in the house mouse
Theiler, K., Varnum, D. S., & Stevens, L. C. (1979) · Anatomy and Embryology · doi:10.1007/bf00315732 · Cited by 78
Small eyes—a new dominant eye mutant in the mouse
Roberts, R. C. (1967) · Genetics Research · doi:10.1017/s0016672300010387 · Cited by 77
Mansouri, A., Stoykova, A., & Gruß, P. (1994) · Journal of Cell Science · doi:10.1242/jcs.1994.supplement_18.5 · Cited by 72
Self-citationR-cadherin expression during nucleus formation in chicken forebrain neuromeres
Ganzler, S., & Redies, C. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-06-04157.1995 · Cited by 71
Development and early postnatal maturation of the primary olfactory cortex
Valverde, F., & Santacana, M. (1994) · Developmental Brain Research · doi:10.1016/0165-3806(94)90093-0 · Cited by 40
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The Glial Nature of Embryonic and Adult Neural Stem Cells
Kriegstein, A., & Alvarez-Buylla, A. (2009) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.051508.135600 · Cited by 2,475
Puelles, L., Kuwana, E., Puelles, E., Bulfone, A., Shimamura, K., Keleher, J., Smiga, S., & Rubenstein, J. L. R. (2000) · The Journal of Comparative Neurology · doi:10.1002/1096-9861(20000828)424:3<409::aid-cne3>3.0.co;2-7 · Cited by 933
Glial cells generate neurons: the role of the transcription factor Pax6
Heins, N., Malatesta, P., Cecconi, F., Nakafuku, M., Tucker, K. L., Hack, M. A., Chapouton, P., Barde, Y.-A., & Götz, M. (2002) · Nature Neuroscience · doi:10.1038/nn828 · Cited by 775
Self-citationMalatesta, P., Hack, M. A., Hartfuss, E., Kettenmann, H., Klinkert, W., Kirchhoff, F., & Götz, M. (2003) · Neuron · doi:10.1016/s0896-6273(03)00116-8 · Cited by 746
Self-citationForebrain gene expression domains and the evolving prosomeric model
Puelles, L., & Rubenstein, J. L. R. (2003) · Trends in Neurosciences · doi:10.1016/s0166-2236(03)00234-0 · Cited by 734
Metadata
- Authors
- Stoykova, A., Götz, M., Gruss, P., & Price, J.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 1997-10-01
- Volume
- 124
- Issue
- 19
- Pages
- 3765-3777
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2170563276
- Cited by
- 285
- References
- 59
- FWCI
- 5.68
- Type
- journal article
- Language
- en
- Open access
- green
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