The DOI matches its Crossref record; 59 of the 59 references it cites were found in a registry or an index.
Pax6-dependent regulation of adhesive patterning, R-cadherin expression and boundary formation in developing forebrain
Open accessAbstract
Mutations in the gene for the transcription factor, Pax6, induce marked developmental abnormalities in the CNS and the eye, but the cellular mechanisms that underlie the phenotype are unknown. We have examined the adhesive properties of cells from the developing forebrain in Small eye, the Pax6 mutant mouse. We have found that the seg-regation normally observed in aggregates of cortical and striatal cells in an in vitro assay is lost in Small eye. This correlates with an alteration of in vivo expression of the homophilic adhesion molecule, R-cadherin. Moreover, the boundary between cortical and striatal regions of the telencephalon is dramatically altered in Small eye: radial glial fascicles do not form at the border, and the normal expression of R-cadherin and tenascin-C at the border is lost. These data suggest a link between the transcription factor, Pax6, R-cadherin expression, cellular adhesion and boundary formation between developing forebrain regions.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Gene regulation by steroid hormones
Beato, M. (1989) · Cell · doi:10.1016/0092-8674(89)90237-7 · Cited by 3,383
Growth of a rat neuroblastoma cell line in serum-free supplemented medium.
Bottenstein, J. E., & Sato, G. H. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.1.514 · Cited by 2,276
Hox genes in vertebrate development
Krumlauf, R. (1994) · Cell · doi:10.1016/0092-8674(94)90290-9 · Cited by 2,073
A protein related to extracellular matrix proteins deleted in the mouse mutant reeler
D'Arcangelo, G., G. Miao, G., Chen, S.-C., Scares, H. D., Morgan, J. I., & Curran, T. (1995) · Nature · doi:10.1038/374719a0 · Cited by 1,748
Erratum: Mouse Small eye results from mutation in a paired-like homebox-containing gene
Hill, R. E., Favor, J., Hogan, B. L. M., Ton, C. C. T., Saunders, G. F., Hanson, I. M., Prosser, J., Jordan, T., Hastie, N. D., & van Heyningen, V. (1992) · Nature · doi:10.1038/355750a0 · Cited by 1,270
Pax-6, a murine paired box gene, is expressed in the developing CNS
Walther, C., & Gruss, P. (1991) · Development · doi:10.1242/dev.113.4.1435 · Cited by 1,255
Self-citationMouse Small eye results from mutations in a paired-like homeobox-containing gene
Hill, R. E., Favor, J., Hogan, B. L. M., Ton, C. C. T., Saunders, G. F., Hanson, I. M., Prosser, J., Jordan, T., Hastie, N. D., & Heyningen, V. V. (1991) · Nature · doi:10.1038/354522a0 · Cited by 1,158
Patterning the Vertebrate Neuraxis
Lumsden, A., & Krumlauf, R. (1996) · Science · doi:10.1126/science.274.5290.1109 · Cited by 1,146
Ogawa, M., Miyata, T., Nakajimat, K., Yagyu, K., Seike, M., Ikenaka, K., Yamamoto, H., & Mikoshibat, K. (1995) · Neuron · doi:10.1016/0896-6273(95)90329-1 · Cited by 889
Nusse, R., & Varmus, H. E. (1992) · Cell · doi:10.1016/0092-8674(92)90630-u · Cited by 815
Cited by
The Glial Nature of Embryonic and Adult Neural Stem Cells
Kriegstein, A., & Alvarez-Buylla, A. (2009) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.051508.135600 · Cited by 2,475
Puelles, L., Kuwana, E., Puelles, E., Bulfone, A., Shimamura, K., Keleher, J., Smiga, S., & Rubenstein, J. L. R. (2000) · The Journal of Comparative Neurology · doi:10.1002/1096-9861(20000828)424:3<409::aid-cne3>3.0.co;2-7 · Cited by 933
Glial cells generate neurons: the role of the transcription factor Pax6
Heins, N., Malatesta, P., Cecconi, F., Nakafuku, M., Tucker, K. L., Hack, M. A., Chapouton, P., Barde, Y.-A., & Götz, M. (2002) · Nature Neuroscience · doi:10.1038/nn828 · Cited by 775
Self-citationMalatesta, P., Hack, M. A., Hartfuss, E., Kettenmann, H., Klinkert, W., Kirchhoff, F., & Götz, M. (2003) · Neuron · doi:10.1016/s0896-6273(03)00116-8 · Cited by 746
Self-citationForebrain gene expression domains and the evolving prosomeric model
Puelles, L., & Rubenstein, J. L. R. (2003) · Trends in Neurosciences · doi:10.1016/s0166-2236(03)00234-0 · Cited by 734
Pax6 Controls Radial Glia Differentiation in the Cerebral Cortex
Götz, M., Stoykova, A., & Gruss, P. (1998) · Neuron · doi:10.1016/s0896-6273(00)80621-2 · Cited by 665
Self-citationAlcántara, S., Ruiz, M., D’Arcangelo, G., Ezan, F., de Lecea, L., Curran, T., Sotelo, C., & Soriano, E. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-19-07779.1998 · Cited by 568
Kukekov, V. G., Laywell, E. D., Suslov, O., Davies, K., Scheffler, B., Thomas, L. B., O'Brien, T. F., Kusakabe, M., & Steindler, D. A. (1999) · Experimental Neurology · doi:10.1006/exnr.1999.7028 · Cited by 522
Gsh2 and Pax6 play complementary roles in dorsoventral patterning of the mammalian telencephalon
Yun, K., Potter, S., & Rubenstein, J. L. R. (2001) · Development · doi:10.1242/dev.128.2.193 · Cited by 450
Genetic control of dorsal-ventral identity in the telencephalon: opposing roles for Pax6 and Gsh2
Toresson, H., Potter, S. S., & Campbell, K. (2000) · Development · doi:10.1242/dev.127.20.4361 · Cited by 391
Radial glia: multi-purpose cells for vertebrate brain development
Campbell, K., & Götz, M. (2002) · Trends in Neurosciences · doi:10.1016/s0166-2236(02)02156-2 · Cited by 388
Self-citationRadial glia diversity: A matter of cell fate
Kriegstein, A. R., & Götz, M. (2003) · Glia · doi:10.1002/glia.10250 · Cited by 370
Self-citationFernandez, A. S., Pieau, C., Repérant, J., Boncinelli, E., & Wassef, M. (1998) · Development · doi:10.1242/dev.125.11.2099 · Cited by 362
Osumi, N., Shinohara, H., Numayama-Tsuruta, K., & Maekawa, M. (2008) · Stem Cells · doi:10.1634/stemcells.2007-0884 · Cited by 344
Tarabykin, V., Stoykova, A., Usman, N., & Gruss, P. (2001) · Development · doi:10.1242/dev.128.11.1983 · Cited by 326
Self-citationLhx2 Selector Activity Specifies Cortical Identity and Suppresses Hippocampal Organizer Fate
Mangale, V. S., Hirokawa, K. E., Satyaki, P. R. V., Gokulchandran, N., Chikbire, S., Subramanian, L., Shetty, A. S., Martynoga, B., Paul, J., Mai, M. V., et al. (2008) · Science · doi:10.1126/science.1151695 · Cited by 316
Cadherins and tissue formation: integrating adhesion and signaling
Vleminckx, K., & Kemler, R. (1999) · BioEssays · doi:10.1002/(sici)1521-1878(199903)21:3<211::aid-bies5>3.0.co;2-p · Cited by 314
Distinctcis-Essential Modules Direct the Time–Space Pattern of thePax6Gene Activity
Kammandel, B., Chowdhury, K., Stoykova, A., Aparicio, S., Brenner, S., & Gruss, P. (1999) · Developmental Biology · doi:10.1006/dbio.1998.9128 · Cited by 279
Self-citationHevner, R. F., Miyashita‐Lin, E., & Rubenstein, J. L. R. (2002) · Journal of Comparative Neurology · doi:10.1002/cne.10219 · Cited by 202
Structural and Functional Aberrations in the Cerebral Cortex of Tenascin-C Deficient Mice
Irintchev, A., Rollenhagen, A., Troncoso, E., Kiss, J. Z., & Schachner, M. (2005) · Cerebral Cortex · doi:10.1093/cercor/bhh195 · Cited by 137
Gene networks controlling early cerebral cortex arealization
Mallamaci, A., & Stoykova, A. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.04634.x · Cited by 95
Self-citationSwanson, D. J., & Goldowitz, D. (2011) · Developmental Biology · doi:10.1016/j.ydbio.2010.11.018 · Cited by 40
Metadata
- Authors
- Stoykova, A., Götz, M., Gruss, P., & Price, J.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 1997-10-01
- Volume
- 124
- Issue
- 19
- Pages
- 3765-3777
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2170563276
- Cited by
- 285
- References
- 59
- FWCI
- 5.68
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
