The DOI matches its Crossref record; 88 of the 88 references it cites were found in a registry or an index.
Zebrafish sparse corresponds to an orthologue of c-kit and is required for the morphogenesis of a subpopulation of melanocytes, but is not essential for hematopoiesis or primordial germ cell development
Abstract
The relative roles of the Kit receptor in promoting the migration and survival of amniote melanocytes are unresolved. We show that, in the zebrafish, Danio rerio, the pigment pattern mutation sparse corresponds to an orthologue of c-kit. This finding allows us to further elucidate morphogenetic roles for this c-kit-related gene in melanocyte morphogenesis. Our analyses of zebrafish melanocyte development demonstrate that the c-kit orthologue identified in this study is required both for normal migration and for survival of embryonic melanocytes. We also find that, in contrast to mouse, the zebrafish c-kit gene that we have identified is not essential for hematopoiesis or primordial germ cell development. These unexpected differences may reflect evolutionary divergence in c-kit functions following gene duplication events in teleosts.
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CSF-1 receptor signaling in myeloid cells.
Stanley, E. R., & Chitu, V. (2014) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a021857 · Cited by 825
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Self-citationZebrafish colourless encodes sox10 and specifies non-ectomesenchymal neural crest fates
Dutton, K. A., Pauliny, A., Lopes, S. S., Elworthy, S., Carney, T. J., Rauch, J., Geisler, R., Haffter, P., & Kelsh, R. N. (2001) · Development · doi:10.1242/dev.128.21.4113 · Cited by 511
Parichy, D. M., Ransom, D. G., Paw, B., Zon, L. I., & Johnson, S. L. (2000) · Development · doi:10.1242/dev.127.14.3031 · Cited by 384
Self-citationSorting out Sox10 functions in neural crest development
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Metadata
- Authors
- Parichy, D. M., Rawls, J. F., Pratt, S. J., Whitfield, T. T., & Johnson, S. L.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 1999-08-01
- Volume
- 126
- Issue
- 15
- Pages
- 3425-3436
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W1718193936
- Cited by
- 311
- References
- 88
- FWCI
- 4.78
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Zebrafish sparse corresponds to an orthologue of c-kit and is required for the morphogenesis of a subpopulation of melanocytes, but is not essential for hematopoiesis or primordial germ cell development. https://app.cochat.ai/papers/10.1242/dev.126.15.3425
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- Parichy, D. M., Rawls, J. F., Pratt, S. J., Whitfield, T. T., & Johnson, S. L. (1999). Zebrafish sparse corresponds to an orthologue of c-kit and is required for the morphogenesis of a subpopulation of melanocytes, but is not essential for hematopoiesis or primordial germ cell development. Development. https://doi.org/10.1242/dev.126.15.3425
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