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Zebrafish sparse corresponds to an orthologue of c-kit and is required for the morphogenesis of a subpopulation of melanocytes, but is not essential for hematopoiesis or primordial germ cell development
Abstract
The relative roles of the Kit receptor in promoting the migration and survival of amniote melanocytes are unresolved. We show that, in the zebrafish, Danio rerio, the pigment pattern mutation sparse corresponds to an orthologue of c-kit. This finding allows us to further elucidate morphogenetic roles for this c-kit-related gene in melanocyte morphogenesis. Our analyses of zebrafish melanocyte development demonstrate that the c-kit orthologue identified in this study is required both for normal migration and for survival of embryonic melanocytes. We also find that, in contrast to mouse, the zebrafish c-kit gene that we have identified is not essential for hematopoiesis or primordial germ cell development. These unexpected differences may reflect evolutionary divergence in c-kit functions following gene duplication events in teleosts.
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Citations
Cites
Analyzing Tables of Statistical Tests
Rice, W. R. (1989) · Evolution · doi:10.2307/2409177 · Cited by 14,571
ANALYZING TABLES OF STATISTICAL TESTS
Rice, W. R. (1989) · Evolution · doi:10.1111/j.1558-5646.1989.tb04220.x · Cited by 14,547
Stages of embryonic development of the zebrafish
Kimmel, C. B., Ballard, W. W., Kimmel, S. R., Ullmann, B., & Schilling, T. F. (1995) · Developmental Dynamics · doi:10.1002/aja.1002030302 · Cited by 12,037
Preservation of Duplicate Genes by Complementary, Degenerative Mutations
Force, A., Lynch, M., Pickett, F. B., Amores, A., Yan, Y.-L., & Postlethwait, J. (1999) · Genetics · doi:10.1093/genetics/151.4.1531 · Cited by 3,529
Zebrafish hox Clusters and Vertebrate Genome Evolution
Amores, A., Force, A., Yan, Y.-L., Joly, L., Amemiya, C., Fritz, A., Ho, R. K., Langeland, J., Prince, V., Wang, Y.-L., et al. (1998) · Science · doi:10.1126/science.282.5394.1711 · Cited by 1,736
Zsebo, K. M., Williams, D. A., Geissler, E. N., Broudy, V. C., Martin, F. H., Atkins, H. L., Hsu, R.-Y., Birkett, N. C., Okino, K. H., Murdock, D. C., et al. (1990) · Cell · doi:10.1016/0092-8674(90)90302-u · Cited by 1,388
Receptor Protein-Tyrosine Kinases and Their Signal Transduction Pathways
van der Geer, P., Hunter, T., & Lindberg, R. A. (1994) · Annual Review of Cell Biology · doi:10.1146/annurev.cb.10.110194.001343 · Cited by 1,326
Huang, E., Nocka, K., Beier, D. R., Chu, T.-Y., Buck, J., Lahm, H.-W., Wellner, D., Leder, P., & Besmer, P. (1990) · Cell · doi:10.1016/0092-8674(90)90303-v · Cited by 1,155
Stem Cell Factor and Hematopoiesis
Broudy, V. C. (1997) · Blood · doi:10.1182/blood.v90.4.1345 · Cited by 858
Anderson, D. M., Lyman, S. D., Baird, A., Wignall, J. M., Eisenman, J., Rauch, C., March, C. J., Boswell, H. S., Gimpel, S. D., Cosman, D., et al. (1990) · Cell · doi:10.1016/0092-8674(90)90304-w · Cited by 831
Hereditary Anemias of the Mouse: A Review for Geneticists
Russell, E. S. (1979) · Advances in Genetics · doi:10.1016/s0065-2660(08)60549-0 · Cited by 766
Qiu, F. H., Ray, P., Brown, K., Barker, P. E., Jhanwar, S., Ruddle, F. H., & Besmer, P. (1988) · The EMBO Journal · doi:10.1002/j.1460-2075.1988.tb02907.x · Cited by 697
Requirement of c-kit for development of intestinal pacemaker system
Maeda, H., Yamagata, A., Nishikawa, S., Yoshinaga, K., Kobayashi, S., Nishi, K., & Nishikawa, S.-I. (1992) · Development · doi:10.1242/dev.116.2.369 · Cited by 697
c-kit Ligand and Flt3 Ligand: Stem/Progenitor Cell Factors With Overlapping Yet Distinct Activities
Lyman, S. D., & Jacobsen, S. E. W. (1998) · Blood · doi:10.1182/blood.v91.4.1101 · Cited by 696
Silvers, W. K. (1979) · Springer eBooks · doi:10.1007/978-1-4612-6164-3 · Cited by 642
Yoon, C., Kawakami, K., & Hopkins, N. (1997) · Development · doi:10.1242/dev.124.16.3157 · Cited by 602
Intraembryonic hematopoietic cell migration during vertebrate development.
Detrich, H. W., Kieran, M. W., Chan, F. Y., Barone, L. M., Yee, K., Rundstadler, J. A., Pratt, S., Ransom, D., & Zon, L. I. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.23.10713 · Cited by 599
Self-citationNocka, K., Tan, J. C., Chiu, E., Chu, T. Y., Ray, P., Traktman, P., & Besmer, P. (1990) · The EMBO Journal · doi:10.1002/j.1460-2075.1990.tb08305.x · Cited by 588
Gene‐induced embryological modifications of primordial germ cells in the mouse
Mintz, B., & Russell, E. S. (1957) · Journal of Experimental Zoology · doi:10.1002/jez.1401340202 · Cited by 541
Schilling, T. F., & Kimmel, C. B. (1994) · Development · doi:10.1242/dev.120.3.483 · Cited by 496
Efficient recovery of ENU-induced mutations from the zebrafish germline.
Solnica-Krezel, L., Schier, A. F., & Driever, W. (1994) · Genetics · doi:10.1093/genetics/136.4.1401 · Cited by 492
Zebrafish pigmentation mutations and the processes of neural crest development
Kelsh, R. N., Brand, M., Jiang, Y.-J., Heisenberg, C.-P., Lin, S., Haffter, P., Odenthal, J., Mullins, M. C., Eeden, F. J. M. V., Furutani-Seiki, M., et al. (1996) · Development · doi:10.1242/dev.123.1.369 · Cited by 455
The Pigmentary System: Physiology and Pathophysiology
Hsin-Su, Y. (1999) · Archives of Dermatology · doi:10.1001/archderm.135.4.478 · Cited by 429
Kim, C. H., & Broxmeyer, H. E. (1998) · Blood · doi:10.1182/blood.v91.1.100 · Cited by 414
Steel, K. P., Davidson, D. R., & Jackson, I. J. (1992) · Development · doi:10.1242/dev.115.4.1111 · Cited by 412
Cell-autonomous action of zebrafish spt-1 mutation in specific mesodermal precursors
Ho, R. K., & Kane, D. A. (1990) · Nature · doi:10.1038/348728a0 · Cited by 386
Mutation of the KIT (mast/stem cell growth factor receptor) protooncogene in human piebaldism.
Giebel, L. B., & Spritz, R. A. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.19.8696 · Cited by 383
Besmer, P., Manova, K., Duttlinger, R., Huang, E. J., Packer, A., Gyssler, C., & Bachvarova, R. F. (1993) · Development · doi:10.1242/dev.119.supplement.125 · Cited by 375
The genetics of pigmentation: from fancy genes to complex traits
Barsh, G. S. (1996) · Trends in Genetics · doi:10.1016/0168-9525(96)10031-7 · Cited by 360
Developmental expression of c-kit, a proto-oncogene encoded by the W locus
Orr-Urtreger, A., Avivi, A., Zimmer, Y., Givol, D., Yarden, Y., & Lonai, P. (1990) · Development · doi:10.1242/dev.109.4.911 · Cited by 347
Mackenzie, M. A. F., Jordan, S. A., Budd, P. S., & Jackson, I. J. (1997) · Developmental Biology · doi:10.1006/dbio.1997.8738 · Cited by 331
Pathways of trunk neural crest cell migration in the mouse embryo as revealed by vital dye labelling
Serbedzija, G. N., Fraser, S. E., & Bronner-Fraser, M. (1990) · Development · doi:10.1242/dev.108.4.605 · Cited by 317
Opdecamp, K., Nakayama, A., Nguyen, M.-T. T., Hodgkinson, C. A., Pavan, W. J., & Arnheiter, H. (1997) · Development · doi:10.1242/dev.124.12.2377 · Cited by 299
Contiguous patterns of c-kit and steel expression: analysis of mutations at the W and Sl loci
Motro, B., Kooy, D. V. D., Rossant, J., Reith, A., & Bernstein, A. (1991) · Development · doi:10.1242/dev.113.4.1207 · Cited by 296
Wehrle-Haller, B., & Weston, J. A. (1995) · Development · doi:10.1242/dev.121.3.731 · Cited by 283
A Laboratory Guide to RNA—Isolation, analysis and synthesis
(1997) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/s1357-2725(97)88592-5 · Cited by 281
The Dominant W 42 Spotting Phenotype Results from a Missense Mutation in the c- kit Receptor Kinase
Tan, J. C., Nocka, K., Ray, P., Traktman, P., & Besmer, P. (1990) · Science · doi:10.1126/science.1688471 · Cited by 273
Characterization of zebrafish mutants with defects in embryonic hematopoiesis
Ransom, D. G., Haffter, P., Odenthal, J., Brownlie, A., Vogelsang, E., Kelsh, R. N., Brand, M., Eeden, F. J. M. V., Furutani-Seiki, M., Granato, M., et al. (1996) · Development · doi:10.1242/dev.123.1.311 · Cited by 265
SEGREGATION ANALYSES AND GENE-CENTROMERE DISTANCES IN ZEBRAFISH
Streisinger, G., Singer, F., Walker, C., Knauber, D., & Dower, N. (1986) · Genetics · doi:10.1093/genetics/112.2.311 · Cited by 245
Spatial and temporal patterns of c-kit-expressing cells in WlacZ/+ and WlacZ/WlacZ mouse embryos
Bernex, F., Sepulveda, P. D., Kress, C., Elbaz, C., Delouis, C., & Panthier, J.-J. (1996) · Development · doi:10.1242/dev.122.10.3023 · Cited by 242
Kunisada, T., Yoshida, H., Yamazaki, H., Miyamoto, A., Hemmi, H., Nishimura, E., Shultz, L. D., Nishikawa, S.-I., & Hayashi, S.-I. (1998) · Development · doi:10.1242/dev.125.15.2915 · Cited by 240
Geissler, E. N., McFarland, E. C., & Russell, E. S. (1981) · Genetics · doi:10.1093/genetics/97.2.337 · Cited by 237
Restriction of neural crest cell fate in the trunk of the embryonic zebrafish
Raible, D. W., & Eisen, J. S. (1994) · Development · doi:10.1242/dev.120.3.495 · Cited by 237
Manova, K., & Bachvarova, R. F. (1991) · Developmental Biology · doi:10.1016/0012-1606(91)90233-s · Cited by 229
Hematopoietic mutations in the zebrafish
Weinstein, B. M., Schier, A. F., Abdelilah, S., Malicki, J., Solnica-Krezel, L., Stemple, D. L., Stainier, D. Y. R., Zwartkruis, F., Driever, W., & Fishman, M. C. (1996) · Development · doi:10.1242/dev.123.1.303 · Cited by 225
Molecular Basis for the Dominant White Phenotype in the Domestic Pig
Marklund, S., Kijas, J., Rodriguez-Martinez, H., Rönnstrand, L., Funa, K., Moller, M., Lange, D., Edfors-Lilja, I., & Andersson, L. (1998) · Genome Research · doi:10.1101/gr.8.8.826 · Cited by 197
Weston, J. A. (1991) · Current Topics in Developmental Biology · doi:10.1016/s0070-2153(08)60414-7 · Cited by 192
Genetic Control of Adult Pigment Stripe Development in Zebrafish
Johnson, S. L., Africa, D., Walker, C., & Weston, J. A. (1995) · Developmental Biology · doi:10.1006/dbio.1995.1004 · Cited by 190
Self-citationYoshida, H., Kunisada, T., Kusakabe, M., Nishikawa, S., & Nishikawa, S.-I. (1996) · Development · doi:10.1242/dev.122.4.1207 · Cited by 186
Centromere-Linkage Analysis and Consolidation of the Zebrafish Genetic Map
Johnson, S. L., Gates, M. A., Johnson, M., Talbot, W. S., Horne, S., Baik, K., Rude, S., Wong, J. R., & Postlethwait, J. H. (1996) · Genetics · doi:10.1093/genetics/142.4.1277 · Cited by 180
Self-citationSteel factor and c-kit regulate cell-matrix adhesion
Kinashi, T., & Springer, T. (1994) · Blood · doi:10.1182/blood.v83.4.1033.1033 · Cited by 173
The Role of Cell-Cell and Cell-Matrix Interactions in the Morphogenesis of the Neural Crest
Erickson, C. A., & Perris, R. (1993) · Developmental Biology · doi:10.1006/dbio.1993.1221 · Cited by 168
Mutations affecting xanthophore pigmentation in the zebrafish, Danio rerio
Odenthal, J., Rossnagel, K., Haffter, P., Kelsh, R. N., Vogelsang, E., Brand, M., van Eeden, F. J. M., Furutani-Seiki, M., Granato, M., Hammerschmidt, M., et al. (1996) · Development · doi:10.1242/dev.123.1.391 · Cited by 161
Vincent, S. D., Segretain, D., Nishikawa, S., et al. (1998) · Development · doi:10.1242/dev.125.22.4585 · Cited by 158
Tsujimura, T., Hirota, S., Nomura, S., Niwa, Y., Yamazaki, M., Tono, T., Morii, E., Kim, H., Kondo, K., & Nishimune, Y. (1991) · Blood · doi:10.1182/blood.v78.8.1942.1942 · Cited by 151
Lin, S., Long, W., Chen, J., & Hopkins, N. H. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.10.4519 · Cited by 149
An experimental analysis of the pigment defect caused by mutations at the W and Sl loci in mice
Mayer, T. C., & Green, M. C. (1968) · Developmental Biology · doi:10.1016/0012-1606(68)90023-7 · Cited by 137
Mutations at the W locus affect survival of neural crest-derived melanocytes in the mouse
Cable, J., Jackson, I. J., & Steel, K. P. (1995) · Mechanisms of Development · doi:10.1016/0925-4773(94)00331-g · Cited by 137
Adachi, S., Ebi, Y., Nishikawa, S., Hayashi, S., Yamazaki, M., Kasugai, T., Yamamura, T., Nomura, S., & Kitamura, Y. (1992) · Blood · doi:10.1182/blood.v79.3.650.650 · Cited by 110
Genetic and epigenetic control in neural crest development
Douarin, N. M. L., Dupin, É., & Ziller, C. (1994) · Current Opinion in Genetics & Development · doi:10.1016/0959-437x(94)90135-p · Cited by 110
KIT Expression Reveals a Population of Precursor Melanocytes in Human Skin
Grichnik, J. M., Ali, W. N., Burch, J. A., Byers, J. D., Garcia, C. A. S., Clark, R. E., & Shea, C. R. (1996) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12338471 · Cited by 103
Hirata, T., Morii, E., Morimoto, M., Kasugai, T., Tsujimura, T., Hirota, S., Kanakura, Y., Nomura, S., & Kitamura, Y. (1993) · Development · doi:10.1242/dev.119.1.49 · Cited by 99
Murphy, M., Reid, K., Williams, D. E., Lyman, S. D., & Bartlett, P. F. (1992) · Developmental Biology · doi:10.1016/0012-1606(92)90124-y · Cited by 95
Iuchi, I., & Yamamoto, M. (1983) · Journal of Experimental Zoology · doi:10.1002/jez.1402260311 · Cited by 92
From the Crest to the Periphery: Control of Pigment Cell Migration and Lineage Segregation
Erickson, C. A. (1993) · Pigment Cell Research · doi:10.1111/j.1600-0749.1993.tb00611.x · Cited by 80
Wehrle‐Haller, B., & Weston, J. A. (1997) · BioEssays · doi:10.1002/bies.950190411 · Cited by 77
Effects of Monoclonal Anti-c-Kit Antibody (ACK2) on Melanocytes in Newborn Mice
Okura, M., Maeda, H., Nishikawa, S., & Mizoguchi, M. (1995) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12319939 · Cited by 75
Contact stimulation of cell migration
Thomas, L. A., & Yamada, K. M. (1992) · Journal of Cell Science · doi:10.1242/jcs.103.4.1211 · Cited by 64
Transient Steel Factor Dependence by Neural Crest-Derived Melanocyte Precursors
Morrison‐Graham, K., & Weston, J. A. (1993) · Developmental Biology · doi:10.1006/dbio.1993.1246 · Cited by 64
Molecular evolution of the genes encoding receptor tyrosine kinase with immunoglobulinlike domains
Rousset, D., Agn�s, F., Lachaume, P., Andr�, C., & Galibert, F. (1995) · Journal of Molecular Evolution · doi:10.1007/bf00160313 · Cited by 63
Reid, K., Nishikawa, S., Bartlett, P. F., & Murphy, M. (1995) · Developmental Biology · doi:10.1006/dbio.1995.1170 · Cited by 63
Avian neural crest-derived neurogenic precursors undergo apoptosis on the lateral migration pathway
Wakamatsu, Y., Mochii, M., Vogel, K. S., & Weston, J. A. (1998) · Development · doi:10.1242/dev.125.21.4205 · Cited by 62
A study of the hereditary anaemia of mice
Aberle, S. B. D. (1927) · American Journal of Anatomy · doi:10.1002/aja.1000400203 · Cited by 61
Russell, E. S. (1949) · Genetics · doi:10.1093/genetics/34.6.708 · Cited by 57
The Occurrence of a Dominant Spotting Mutation in the House Mouse
Little, C. C., & Cloudman, A. M. (1937) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.23.10.535 · Cited by 57
7 Neural Crest Diversification
Groves, A. K., & Bronner-Fraser, M. E. (1998) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/s0070-2153(08)60383-x · Cited by 52
Multiple Actions of Stem Cell Factor in Neural Crest Cell Differentiationin Vitro
Langtimm, C. J., Schroeder, B., Saskowski, J. L., Carnahan, J. F., & Sieber‐Blum, M. (1996) · Developmental Biology · doi:10.1006/dbio.1996.0079 · Cited by 50
Effect of the Steel gene product on melanogenesis in avian neural crest cell cultures
Lahav, R., Lecoin, L., Ziller, C., et al. (1995) · Differentiation · doi:10.1046/j.1432-0436.1995.5820133.x · Cited by 48
Stem Cell Factor Regulates Human Melanocyte‐Matrix Interactions
SCOTT, G. A., Ewing, J. F., Ryan, D. H., & Abboud, C. N. (1994) · Pigment Cell Research · doi:10.1111/j.1600-0749.1994.tb00017.x · Cited by 47
Lecoin, L., Lahav, R., Martin, F. H., Teillet, M., & Douarin, N. M. L. (1995) · Developmental Dynamics · doi:10.1002/aja.1002030111 · Cited by 45
Parichy, D. M. (1996) · Developmental Biology · doi:10.1006/dbio.1996.0114 · Cited by 45
Self-citationThe control of pigment cell pattern formation in the California newt, Taricha torosa
Tucker, R. P., & Erickson, C. A. (1986) · Development · doi:10.1242/dev.97.1.141 · Cited by 34
Baker, C. V. H., Sharpe, C. R., Torpey, N., Heasman, J., & Wylie, C. C. (1995) · Mechanisms of Development · doi:10.1016/0925-4773(94)00338-n · Cited by 30
Expression of Xkl-1, a Xenopus gene related to mammalian c-kit, in dorsal embryonic tissue
Kao, K., & Bernstein, A. (1995) · Mechanisms of Development · doi:10.1016/0925-4773(94)00325-h · Cited by 21
Parichy, D. M. (1996) · The International Journal of Developmental Biology · doi:10.1387/ijdb.8877461 · Cited by 19
Self-citationParichy, D. M., Stigson, M., & Voss, S. R. (1999) · Development Genes and Evolution · doi:10.1007/s004270050263 · Cited by 16
Self-citationThe c‐kit receptor ligand functions as a mast cell chemoattractant
Meininger, C., Yano, H., Rottapel, R., Bernstein, A., Zsebo, K., & Zetter, B. (1992) · Blood · doi:10.1182/blood.v79.4.958.958 · Cited by 10
Direct In Situ End-Labeling for Detection of Apoptotic Cells in Tissue Sections
Zhang, Z., & Galileo, D. S. (1997) · BioTechniques · doi:10.2144/97225bm09 · Cited by 7
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Lister, J. A., Robertson, C. P., Lepage, T., Johnson, S. L., & Raible, D. W. (1999) · Development · doi:10.1242/dev.126.17.3757 · Cited by 819
Self-citationZebrafish colourless encodes sox10 and specifies non-ectomesenchymal neural crest fates
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Parichy, D. M., Ransom, D. G., Paw, B., Zon, L. I., & Johnson, S. L. (2000) · Development · doi:10.1242/dev.127.14.3031 · Cited by 384
Self-citationSorting out Sox10 functions in neural crest development
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Metadata
- Authors
- Parichy, D. M., Rawls, J. F., Pratt, S. J., Whitfield, T. T., & Johnson, S. L.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 1999-08-01
- Volume
- 126
- Issue
- 15
- Pages
- 3425-3436
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W1718193936
- Cited by
- 311
- References
- 88
- FWCI
- 4.78
- Type
- journal article
- Language
- en
- Open access
- closed
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