The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Retinoids are produced by glia in the lateral ganglionic eminence and regulate striatal neuron differentiation
Abstract
In order to identify molecular mechanisms involved in striatal development, we employed a subtraction cloning strategy to enrich for genes expressed in the lateral versus the medial ganglionic eminence. Using this approach, the homeobox gene Meis2 was found highly expressed in the lateral ganglionic eminence and developing striatum. Since Meis2 has recently been shown to be upregulated by retinoic acid in P19 EC cells (Oulad-Abdelghani, M., Chazaud, C., Bouillet, P., Sapin, V., Chambon, P. and Dollé,P. (1997) Dev. Dyn. 210, 173-183), we examined a potential role for retinoids in striatal development. Our results demonstrate that the lateral ganglionic eminence, unlike its medial counterpart or the adjacent cerebral cortex, is a localized source of retinoids. Interestingly, glia (likely radial glia) in the lateral ganglionic eminence appear to be a major source of retinoids. Thus, as lateral ganglionic eminence cells migrate along radial glial fibers into the developing striatum, retinoids from these glial cells could exert an effect on striatal neuron differentiation. Indeed, the treatment of lateral ganglionic eminence cells with retinoic acid or agonists for the retinoic acid receptors or retinoid X receptors, specifically enhances their striatal neuron characteristics. These findings, therefore, strongly support the notion that local retinoid signalling within the lateral ganglionic eminence regulates striatal neuron differentiation.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Retinoic acid biosynthesis and metabolism
Napoli, J. L. (1996) · The FASEB Journal · doi:10.1096/fasebj.10.9.8801182 · Cited by 378
Embryonic development and pattern formation
Morriss‐Kay, G. M., & Sokolova, N. (1996) · The FASEB Journal · doi:10.1096/fasebj.10.9.8801178 · Cited by 203
Cited by
Neuronal replacement from endogenous precursors in the adult brain after stroke
Arvidsson, A., Collin, T., Kirik, D., Kokaia, Z., & Lindvall, O. (2002) · Nature Medicine · doi:10.1038/nm747 · Cited by 2,799
Decreased expression of striatal signaling genes in a mouse model of Huntington's disease
Luthi-Carter, R. (2000) · Human Molecular Genetics · doi:10.1093/hmg/9.9.1259 · Cited by 720
Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation
Park, H. L., Bai, C., Platt, K. A., Matise, M. P., Beeghly, A., Hui, C. C., Nakashima, M., & Joyner, A. L. (2000) · Development · doi:10.1242/dev.127.8.1593 · Cited by 718
Origin and Molecular Specification of Striatal Interneurons
Marı́n, O., Anderson, S. A., & Rubenstein, J. L. R. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-16-06063.2000 · Cited by 631
The caudal ganglionic eminence is a source of distinct cortical and subcortical cell populations
Nery, S., Fishell, G., & Corbin, J. G. (2002) · Nature Neuroscience · doi:10.1038/nn971 · Cited by 558
T HE R OLE OF V ITAMIN A IN M AMMALIAN R EPRODUCTION AND E MBRYONIC D EVELOPMENT
Clagett-Dame, M., & DeLuca, H. F. (2002) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.22.010402.102745e · Cited by 461
Genetic control of dorsal-ventral identity in the telencephalon: opposing roles for Pax6 and Gsh2
Toresson, H., Potter, S. S., & Campbell, K. (2000) · Development · doi:10.1242/dev.127.20.4361 · Cited by 391
Self-citationRadial glia: multi-purpose cells for vertebrate brain development
Campbell, K., & Götz, M. (2002) · Trends in Neurosciences · doi:10.1016/s0166-2236(02)02156-2 · Cited by 388
Self-citationRadial glia diversity: A matter of cell fate
Kriegstein, A. R., & Götz, M. (2003) · Glia · doi:10.1002/glia.10250 · Cited by 370
A role for Gbx2 in repression of Otx2 and positioning the mid/hindbrain organizer
Millet, S., Campbell, K., Epstein, D. J., Losos, K., Harris, E., & Joyner, A. L. (1999) · Nature · doi:10.1038/43664 · Cited by 358
Self-citationRallu, M., Machold, R., Gaiano, N., Corbin, J. G., McMahon, A. P., & Fishell, G. (2002) · Development · doi:10.1242/dev.129.21.4963 · Cited by 280
Radial glial cell heterogeneity—The source of diverse progeny in the CNS
PINTO, L., & GOTZ, M. (2007) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2007.02.010 · Cited by 260
Ehrman, L. A., Mu, X., Waclaw, R. R., Yoshida, Y., Vorhees, C. V., Klein, W. H., & Campbell, K. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1308275110 · Cited by 79
Self-citationRadial glia in the ventral telencephalon
Turrero García, M., & Harwell, C. C. (2017) · FEBS Letters · doi:10.1002/1873-3468.12829 · Cited by 62
Diverse functions of retinoic acid in brain vascular development.
Bonney, S., Harrison-Uy, S., Mishra, S., MacPherson, A. M., Choe, Y., Li, D., Jaminet, S.-C., Fruttiger, M., Pleasure, S. J., & Siegenthaler, J. A. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.3952-15.2016 · Cited by 40
Effects of retinoic acid on ischemic brain injury-induced neurogenesis.
Jung, D.-S., Baek, S.-Y., Park, K.-H., Chung, Y.-I., Kim, H.-J., Kim, C.-D., Cho, M.-K., Han, M.-E., Park, K.-P., Kim, B.-S., et al. (2007) · Experimental & Molecular Medicine · doi:10.1038/emm.2007.34 · Cited by 10
Metadata
- Authors
- Toresson, H., Urquiza, A. M. D., Fagerström, C., Perlmann, T., & Campbell, K.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 1999-03-15
- Volume
- 126
- Issue
- 6
- Pages
- 1317-1326
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2150207739
- Cited by
- 203
- References
- 2
- FWCI
- 3.46
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
