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Cited by 698

The DOI matches its Crossref record; 193 of the 193 references it cites were found in a registry or an index.

Development of the human placenta

Open access
Turco, Margherita Y., Moffett, Ashley·2019·Development

Abstract

The placenta is essential for normal in utero development in mammals. In humans, defective placental formation underpins common pregnancy disorders such as pre-eclampsia and fetal growth restriction. The great variation in placental types across mammals means that animal models have been of limited use in understanding human placental development. However, new tools for studying human placental development, including 3D organoids, stem cell culture systems and single cell RNA sequencing, have brought new insights into this field. Here, we review the morphological, molecular and functional aspects of human placental formation, with a focus on the defining cell of the placenta – the trophoblast.

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Show all 193 references

Research works printed but not linked: 18

  1. Abou-Kheir, 2017, HTR-8/SVneo cell line contains a mixed population of cells, Placenta, 50, 1, 10.1016/j.placenta.2016.12.007 · doi:10.1016/j.placenta.2016.12.007
  2. Arias-Stella, 1954, Atypical endometrial changes associated with the presence of chorionic tissue, AMA Arch. Pathol., 52, 112
  3. Gaunt, 1986, Microinjection of human placenta. II: Biological application, Placenta, 7, 325, 10.1016/S0143-4004(86)80150-3 · doi:10.1016/s0143-4004(86)80150-3
  4. Gerbaud, 2011, Mesenchymal activin-A overcomes defective human trisomy 21 trophoblast fusion, Endocrinology, 152, 5017, 10.1210/en.2011-1193 · doi:10.1210/en.2011-1193
  5. Hayward, 2007, Distribution of human endogenous retrovirus type W receptor in normal human villous placenta, Pathology, 39, 406, 10.1080/00313020701444572 · doi:10.1080/00313020701444572
  6. Hertz, 1959, Choriocarcinoma of women maintained in serial passage in hamster and rat, Proc. Soc. Exp. Biol. Med., 102, 77, 10.3181/00379727-102-25149 · doi:10.3181/00379727-102-25149
  7. Jain, 2017, Deciphering transcriptional regulation in human embryonic stem cells specified towards a trophoblast fate, Sci. Rep., 7, 17257, 10.1038/s41598-017-17614-5 · doi:10.1038/s41598-017-17614-5
  8. James, 2007, The isolation and characterization of a population of extravillous trophoblast progenitors from first trimester human placenta, Hum. Reprod., 22, 2111, 10.1093/humrep/dem144 · doi:10.1093/humrep/dem144
  9. Jokhi, 1994, Reciprocal expression of epidermal growth factor receptor (EGF-R) and c-erbB2 by non-invasive and invasive human trophoblast populations, Cytokine, 6, 433, 10.1016/1043-4666(94)90068-X · doi:10.1016/1043-4666(94)90068-x
  10. Kagami, 2012, Paternal uniparental disomy 14 and related disorders, Epigenetics, 7, 1142, 10.4161/epi.21937 · doi:10.4161/epi.21937
  11. Kauma, 1997, The differential expression of hepatocyte growth factor and met in human placenta, J. Clin. Endocrinol. Metab., 82, 949, 10.1210/jc.82.3.949 · doi:10.1210/jc.82.3.949
  12. Ladines-Llave, 2013, Cytologic localization of epidermal growth factor and its receptor in developing human placenta varies over the course of pregnancy, Am. J. Obstet. Gynecol., 165, 1377, 10.1016/0002-9378(91)90372-X · doi:10.1016/0002-9378(91)90372-x
  13. Liang, 2010, GCM1 regulation of the expression of syncytin 2 and its cognate receptor MFSD2A in human placenta, Biol. Reprod., 83, 387, 10.1095/biolreprod.110.083915 · doi:10.1095/biolreprod.110.083915
  14. Male, 2012, Isolation of cells from the feto-maternal interface, Curr. Protoc. Immunol., 97, 7.40.1, 10.1002/0471142735.im0740s97 · doi:10.1002/0471142735.im0740s97
  15. Mirkovic, 2015, GATA3 expression in gestational trophoblastic tissues and tumours, Histopathology, 67, 636, 10.1111/his.12681 · doi:10.1111/his.12681
  16. Pijnenborg, 2013, A.A.W. Hubrecht and the naming of the trophoblast, Placenta, 34, 314, 10.1016/j.placenta.2013.01.002 · doi:10.1016/j.placenta.2013.01.002
  17. Stefanoska, 2013, Prolactin stimulates cell migration and invasion by human trophoblast in vitro, Placenta, 34, 775, 10.1016/j.placenta.2013.06.305 · doi:10.1016/j.placenta.2013.06.305
  18. Xu, 2000, Expression of matrix metalloproteinase-2, -9, and -14, tissue inhibitors of metalloproteinase-1, and matrix proteins in human placenta during the first trimester, Biol. Reprod., 62, 988, 10.1095/biolreprod62.4.988 · doi:10.1095/biolreprod62.4.988

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Metadata

Authors
Turco, M. Y., & Moffett, A.
Venue
Development
Published
2019-11-15
Volume
146
Issue
22
ISSN
  • 0950-1991 (ISSN-L)
  • 1477-9129
OpenAlex
W2990237704
Cited by
698
References
193
FWCI
59.53
Type
journal article
Language
en
Open access
hybrid
Funders
  • Wellcome Trust (200841/Z/16/Z)
  • Medical Research Council (MR/P001092/1)
  • Royal Society (DH160216 RGF\R1\180028)

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CoChat. (2026). Citation check: Development of the human placenta. https://app.cochat.ai/papers/10.1242/dev.163428
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Turco, M. Y., & Moffett, A. (2019). Development of the human placenta. Development. https://doi.org/10.1242/dev.163428

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